Control of protein-protein interactions: Structure-based discovery of low molecular weight inhibitors of the interactions between Pin1 WW domain and phosphopeptides

Journal of Medicinal Chemistry

Volumn 48, Issue 15, 2005, Pages 4815-4823

  Smet, Caroline ^a   Duckert, Jean Frédéric ^a   Wieruszeski, Jean Michel ^a   Landrieu, Isabelle ^a   Buée, Luc ^b   Lippens, Guy ^a   Déprez, Benoît ^a  

^a UNIV LILLE   (France)

^b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLTHREONYLPHOSPHONOPROLINAMIDE; DIPEPTIDE; ISOMERASE; LIGAND; PEPTIDYLPROLYL ISOMERASE PIN1; PHOSPHOPEPTIDE; PROLINE; PROTEIN INHIBITOR; SERINE; THREONINE; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR WEIGHT; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

BINDING SITES; BINDING, COMPETITIVE; CELL LINE, TUMOR; DIPEPTIDES; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PEPTIDYLPROLYL ISOMERASE; PHOSPHOPEPTIDES; PHOSPHOPROTEINS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 22744432396     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0500119     Document Type: Article

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