Aryl indanyl ketones: Efficient inhibitors of the human peptidyl prolyl cis/trans isomerase pin1

Angewandte Chemie - International Edition

Volumn 45, Issue 44, 2006, Pages 7454-7458

  Daum, Sebastian ^b   Erdmann, Frank ^b   Fischer, Gunter ^b   De Lacroix, Boris Féaux ^a   Hessamian Alinejad, Anahita ^a   Houben, Sabine ^a   Frank, Walter ^a   Braun, Manfred ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b MAX PLANCK RESEARCH UNIT FOR ENZYMOLOGY OF PROTEIN FOLDING   (Germany)

Author keywords

Antitumor agents; Biological activity; Chirality; Enzymes; Ketones

Indexed keywords

AMINO ACIDS; CATALYSIS; CELLS; ENZYME INHIBITION; ONCOLOGY;

ANTITUMOR AGENTS; BIOLOGICAL ACTIVITY; CHIRALITY; PEPTIDES;

KETONES;

KETONE; NIMA INTERACTING PEPTIDYLPROLYL ISOMERASE; NIMA-INTERACTING PEPTIDYLPROLYL ISOMERASE; PEPTIDYLPROLYL ISOMERASE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ENZYME SPECIFICITY; HUMAN;

HUMANS; KETONES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PEPTIDYLPROLYL ISOMERASE; SUBSTRATE SPECIFICITY;

EID: 33751234234     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200601569     Document Type: Article

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