Modeling breast cancer in vivo and ex vivo reveals an essential role of Pin1 in tumorigenesis

EMBO Journal

Volumn 23, Issue 16, 2004, Pages 3397-3407

  Wulf, Gerburg ^a   Garg, Priti ^a   Liou, Yih Cherng ^a,c   Iglehart, Dirk ^b   Lu, Kun Ping ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Pin1; Protein phosphorylation; Three dimensional culture; Transgenic mice; Tumorigenesis

Indexed keywords

CYCLIN D1; PEPTIDYLPROLYL ISOMERASE PIN1; PROLINE; PROTEIN; SERINE; THREONINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST DEVELOPMENT; BREAST EPITHELIUM; CANCER; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CONTROLLED STUDY; CYCLIN D1 GENE; EX VIVO STUDY; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC PREDISPOSITION; IN VIVO STUDY; MALIGNANT TRANSFORMATION; MOUSE; MOUSE STRAIN; NONHUMAN; ONCOGENE MYC; ONCOGENE NEU; ONCOGENE RAS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; SERINE THREONINE PROLINE MOTIF; TRANSGENE; TRANSGENIC MOUSE;

ANIMALS; BREAST NEOPLASMS; CELL DIFFERENTIATION; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CYCLIN D1; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; MALE; MAMMARY GLANDS, ANIMAL; MICE; MICE, NUDE; MICE, TRANSGENIC; PEPTIDYLPROLYL ISOMERASE; PHENOTYPE; PROTO-ONCOGENE PROTEINS C-MYC; RAS PROTEINS; RECEPTOR, ERBB-2; SEXUAL ABSTINENCE;

ANIMALIA; MUS MUSCULUS;

EID: 4444309643     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600323     Document Type: Article

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