-
1
-
-
0141709594
-
Pin1 is a novel prognostic marker in prostate cancer
-
in press
-
Ayala G., Wang D., Wulf G., Frolov A., Le R., Wheeler T., Sowadski J.M., Lu K.P., Bao L. Pin1 is a novel prognostic marker in prostate cancer. Cancer Res. in press:2003.
-
(2003)
Cancer Res.
-
-
Ayala, G.1
Wang, D.2
Wulf, G.3
Frolov, A.4
Le, R.5
Wheeler, T.6
Sowadski, J.M.7
Lu, K.P.8
Bao, L.9
-
2
-
-
0035902180
-
Oncogenic kinase signalling
-
Blume-Jensen P., Hunter T. Oncogenic kinase signalling. Nature. 411:2001;355-365.
-
(2001)
Nature
, vol.411
, pp. 355-365
-
-
Blume-Jensen, P.1
Hunter, T.2
-
3
-
-
0035253619
-
Juglone, an inhibitor of the peptidyl-prolyl isomerase Pin1, also directly blocks transcription
-
Chao S.H., Greenleaf A.L., Price D.H. Juglone, an inhibitor of the peptidyl-prolyl isomerase Pin1, also directly blocks transcription. Nucleic Acids Res. 29:2001;767-773.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 767-773
-
-
Chao, S.H.1
Greenleaf, A.L.2
Price, D.H.3
-
4
-
-
0038518619
-
Practical management of patients with chronic myeloid leukemia receiving imatinib
-
Deininger M.W., O'Brien S.G., Ford J.M., Druker B.J. Practical management of patients with chronic myeloid leukemia receiving imatinib. J. Clin. Oncol. 21:2003;1637-1647.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 1637-1647
-
-
Deininger, M.W.1
O'Brien, S.G.2
Ford, J.M.3
Druker, B.J.4
-
5
-
-
0035939903
-
Delineation of prognostic biomarkers in prostate cancer
-
Dhanasekaran S.M., Barrette T.R., Ghosh D., Shah R., Varambally S., Kurachi K., Pienta K.J., Rubin M.A., Chinnaiyan A.M. Delineation of prognostic biomarkers in prostate cancer. Nature. 412:2001;822-826.
-
(2001)
Nature
, vol.412
, pp. 822-826
-
-
Dhanasekaran, S.M.1
Barrette, T.R.2
Ghosh, D.3
Shah, R.4
Varambally, S.5
Kurachi, K.6
Pienta, K.J.7
Rubin, M.A.8
Chinnaiyan, A.M.9
-
6
-
-
0036463948
-
Perspectives on the development of a molecularly targeted agent
-
Druker B.J. Perspectives on the development of a molecularly targeted agent. Cancer Cell. 1:2002;31-36.
-
(2002)
Cancer Cell
, vol.1
, pp. 31-36
-
-
Druker, B.J.1
-
7
-
-
0033619755
-
Mice lacking Pin1 develop normally, but are defective in entering cell cycle from G(0) arrest
-
Fujimori F., Takahashi K., Uchida C., Uchida T. Mice lacking Pin1 develop normally, but are defective in entering cell cycle from G(0) arrest. Biochem. Biophys. Res. Commun. 265:1999;658-663.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.265
, pp. 658-663
-
-
Fujimori, F.1
Takahashi, K.2
Uchida, C.3
Uchida, T.4
-
8
-
-
0036323564
-
The development and clinical use of trastuzumab (Herceptin)
-
Harries M., Smith I. The development and clinical use of trastuzumab (Herceptin). Endocr. Relat. Cancer. 9:2002;75-85.
-
(2002)
Endocr. Relat. Cancer
, vol.9
, pp. 75-85
-
-
Harries, M.1
Smith, I.2
-
9
-
-
0032574832
-
Selective inactivation of parvulin-like peptidyl-prolyl cis/trans isomerases by juglone
-
Hennig L., Christner C., Kipping M., Schelbert B., Rucknagel K.P., Grabley S., Kullertz G., Fischer G. Selective inactivation of parvulin-like peptidyl-prolyl cis/trans isomerases by juglone. Biochemistry. 37:1998;5953-5960.
-
(1998)
Biochemistry
, vol.37
, pp. 5953-5960
-
-
Hennig, L.1
Christner, C.2
Kipping, M.3
Schelbert, B.4
Rucknagel, K.P.5
Grabley, S.6
Kullertz, G.7
Fischer, G.8
-
10
-
-
0032559238
-
Prolyl isomerase and nuclear function
-
Hunter T. Prolyl isomerase and nuclear function. Cell. 92:1998;141-143.
-
(1998)
Cell
, vol.92
, pp. 141-143
-
-
Hunter, T.1
-
11
-
-
0034636153
-
Beta-catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression
-
Lin S.Y., Xia W., Wang J.C., Kwong K.Y., Spohn B., Wen Y., Pestell R.G., Hung M.C. Beta-catenin, a novel prognostic marker for breast cancer. its roles in cyclin D1 expression and cancer progression Proc. Natl. Acad. Sci. USA. 97:2000;4262-4266.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 4262-4266
-
-
Lin, S.Y.1
Xia, W.2
Wang, J.C.3
Kwong, K.Y.4
Spohn, B.5
Wen, Y.6
Pestell, R.G.7
Hung, M.C.8
-
12
-
-
0037022355
-
Loss of Pin1 function in the mouse resembles the cyclin D1-null phenotypes
-
Liou Y.C., Ryo R., Huang H.K., Lu P.J., Bronson R., Fujimori F., Uchida U., Hunter T., Lu K.P. Loss of Pin1 function in the mouse resembles the cyclin D1-null phenotypes. Proc. Natl. Acad. Sci. USA. 99:2002;1335-1340.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 1335-1340
-
-
Liou, Y.C.1
Ryo, R.2
Huang, H.K.3
Lu, P.J.4
Bronson, R.5
Fujimori, F.6
Uchida, U.7
Hunter, T.8
Lu, K.P.9
-
13
-
-
0043069764
-
Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration
-
Liou Y.-C., Sun A., Ryo A., Zhou X.Z., Yu Z.-X., Huang H.-K., Bronson R., Bing G., Li X., Hunter T., Lu K.P. Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration. Nature. 424:2003;556-561.
-
(2003)
Nature
, vol.424
, pp. 556-561
-
-
Liou, Y.-C.1
Sun, A.2
Ryo, A.3
Zhou, X.Z.4
Yu, Z.-X.5
Huang, H.-K.6
Bronson, R.7
Bing, G.8
Li, X.9
Hunter, T.10
Lu, K.P.11
-
14
-
-
0029916122
-
A human peptidyl-prolyl isomerase essential for regulation of mitosis
-
Lu K.P., Hanes S.D., Hunter T. A human peptidyl-prolyl isomerase essential for regulation of mitosis. Nature. 380:1996;544-547.
-
(1996)
Nature
, vol.380
, pp. 544-547
-
-
Lu, K.P.1
Hanes, S.D.2
Hunter, T.3
-
15
-
-
0033600242
-
The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein
-
a
-
Lu P.J., Wulf G., Zhou X.Z., Davies P., Lu K.P. The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein. Nature. 399:1999;784-788. a.
-
(1999)
Nature
, vol.399
, pp. 784-788
-
-
Lu, P.J.1
Wulf, G.2
Zhou, X.Z.3
Davies, P.4
Lu, K.P.5
-
16
-
-
0040017910
-
A function of WW domains as phosphoserine- or phosphothreonine-binding modules
-
b
-
Lu P.J., Zhou X.Z., Shen M., Lu K.P. A function of WW domains as phosphoserine- or phosphothreonine-binding modules. Science. 283:1999;1325-1328. b.
-
(1999)
Science
, vol.283
, pp. 1325-1328
-
-
Lu, P.J.1
Zhou, X.Z.2
Shen, M.3
Lu, K.P.4
-
17
-
-
0037169479
-
Critical role of WW domain phosphorylation in regulating its phosphoserine-binding activity and the Pin1 function
-
a
-
Lu P.J., Zhou X.Z., Liou Y.C., Noel J.P., Lu K.P. Critical role of WW domain phosphorylation in regulating its phosphoserine-binding activity and the Pin1 function. J. Biol. Chem. 277:2002;2381-2384. a.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 2381-2384
-
-
Lu, P.J.1
Zhou, X.Z.2
Liou, Y.C.3
Noel, J.P.4
Lu, K.P.5
-
18
-
-
0036535975
-
Pinning down the proline-directed phosphorylation signaling
-
b
-
Lu K.P., Liou Y.C., Zhou X.Z. Pinning down the proline-directed phosphorylation signaling. Trends Cell Biol. 12:2002;164-172. b.
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 164-172
-
-
Lu, K.P.1
Liou, Y.C.2
Zhou, X.Z.3
-
19
-
-
0035063183
-
The Rb/E2F pathway and cancer
-
Nevins J.R. The Rb/E2F pathway and cancer. Hum. Mol. Genet. 10:2001;699-703.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 699-703
-
-
Nevins, J.R.1
-
20
-
-
0008233581
-
Structural and functional analysis of the mitotic peptidyl-prolyl isomerase Pin1 suggests that substrate recognition is phosphorylation dependent
-
Ranganathan R., Lu K.P., Hunter T., Noel J.P. Structural and functional analysis of the mitotic peptidyl-prolyl isomerase Pin1 suggests that substrate recognition is phosphorylation dependent. Cell. 89:1997;875-886.
-
(1997)
Cell
, vol.89
, pp. 875-886
-
-
Ranganathan, R.1
Lu, K.P.2
Hunter, T.3
Noel, J.P.4
-
21
-
-
0033854422
-
Phosphorylation-dependent proline isomerization catalyzed by Pin1 is essential for tumor cell survival and entry into mitosis
-
Rippmann J.F., Hobbie S., Daiber C., Guilliard B., Bauer M., Birk J., Nar H., Garin-Chesa P., Rettig W.J., Schnapp A. Phosphorylation-dependent proline isomerization catalyzed by Pin1 is essential for tumor cell survival and entry into mitosis. Cell Growth Differ. 11:2000;409-416.
-
(2000)
Cell Growth Differ.
, vol.11
, pp. 409-416
-
-
Rippmann, J.F.1
Hobbie, S.2
Daiber, C.3
Guilliard, B.4
Bauer, M.5
Birk, J.6
Nar, H.7
Garin-Chesa, P.8
Rettig, W.J.9
Schnapp, A.10
-
22
-
-
0034840950
-
Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC
-
Ryo A., Nakamura N., Wulf G., Liou Y.C., Lu K.P. Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC. Nat. Cell Biol. 3:2001;793-801.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 793-801
-
-
Ryo, A.1
Nakamura, N.2
Wulf, G.3
Liou, Y.C.4
Lu, K.P.5
-
23
-
-
0036315162
-
Pin1 is an E2F target gene essential for the Neu/Ras-induced transformation of mammary epithelial cells
-
Ryo A., Liou Y.C., Wulf G., Nakamura N., Lee S.W., Lu K.P. Pin1 is an E2F target gene essential for the Neu/Ras-induced transformation of mammary epithelial cells. Mol. Cell. Biol. 22:2002;5281-5295.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 5281-5295
-
-
Ryo, A.1
Liou, Y.C.2
Wulf, G.3
Nakamura, N.4
Lee, S.W.5
Lu, K.P.6
-
24
-
-
0037351048
-
Prolyl isomerase Pin1, a catalyst for oncogenesis and a potential anticancer target
-
Ryo A., Liou Y.C., Lu K.P., Wulf G. Prolyl isomerase Pin1, a catalyst for oncogenesis and a potential anticancer target. J. Cell Sci. 116:2003;773-783.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 773-783
-
-
Ryo, A.1
Liou, Y.C.2
Lu, K.P.3
Wulf, G.4
-
25
-
-
0032031634
-
The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins
-
Shen M., Stukenberg P.T., Kirschner M.W., Lu K.P. The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins. Genes Dev. 12:1998;706-720.
-
(1998)
Genes Dev.
, vol.12
, pp. 706-720
-
-
Shen, M.1
Stukenberg, P.T.2
Kirschner, M.W.3
Lu, K.P.4
-
26
-
-
19044391072
-
Gene expression correlates of clinical prostate cancer behavior
-
Singh D., Febbo P.G., Ross K., Jackson D.G., Manola J., Ladd C., Tamayo P., Renshaw A.A., D'Amico A.V., Richie J.P.et al. Gene expression correlates of clinical prostate cancer behavior. Cancer Cell. 1:2002;203-209.
-
(2002)
Cancer Cell
, vol.1
, pp. 203-209
-
-
Singh, D.1
Febbo, P.G.2
Ross, K.3
Jackson, D.G.4
Manola, J.5
Ladd, C.6
Tamayo, P.7
Renshaw, A.A.8
D'Amico, A.V.9
Richie, J.P.10
-
27
-
-
0037256548
-
Pin1 and Par14 peptidyl prolyl isomerase inhibitors block cell proliferation
-
Uchida T., Takamiya M., Takahashi M., Miyashita H., Ikeda H., Terada T., Matsuo Y., Shirouzu M., Yokoyama S., Fujimori F., Hunter T. Pin1 and Par14 peptidyl prolyl isomerase inhibitors block cell proliferation. Chem. Biol. 10:2003;15-24.
-
(2003)
Chem. Biol.
, vol.10
, pp. 15-24
-
-
Uchida, T.1
Takamiya, M.2
Takahashi, M.3
Miyashita, H.4
Ikeda, H.5
Terada, T.6
Matsuo, Y.7
Shirouzu, M.8
Yokoyama, S.9
Fujimori, F.10
Hunter, T.11
-
28
-
-
0342322902
-
Evidence that the substrate backbone conformation is critical to phosphorylation by p42 MAP kinase
-
Weiwad M., Kullertz G., Schutkowski M., Fischer G. Evidence that the substrate backbone conformation is critical to phosphorylation by p42 MAP kinase. FEBS Lett. 478:2000;39-42.
-
(2000)
FEBS Lett.
, vol.478
, pp. 39-42
-
-
Weiwad, M.1
Kullertz, G.2
Schutkowski, M.3
Fischer, G.4
-
29
-
-
0035796405
-
Pin1 is overexpressed in breast cancer and potentiates the transcriptional activity of phosphorylated c-Jun towards the cyclin D1 gene
-
Wulf G.M., Ryo A., Wulf G.G., Lee S.W., Niu T., Lu K.P. Pin1 is overexpressed in breast cancer and potentiates the transcriptional activity of phosphorylated c-Jun towards the cyclin D1 gene. EMBO J. 20:2001;3459-3472.
-
(2001)
EMBO J.
, vol.20
, pp. 3459-3472
-
-
Wulf, G.M.1
Ryo, A.2
Wulf, G.G.3
Lee, S.W.4
Niu, T.5
Lu, K.P.6
-
30
-
-
0037073713
-
Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage
-
Wulf G.M., Liou Y.C., Ryo A., Lee S.W., Lu K.P. Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage. J. Biol. Chem. 277:2002;47976-47979.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 47976-47979
-
-
Wulf, G.M.1
Liou, Y.C.2
Ryo, A.3
Lee, S.W.4
Lu, K.P.5
-
31
-
-
0031438929
-
Sequence-specific and phosphorylation-dependent proline isomerization: A potential mitotic regulatory mechanism
-
Yaffe M.B., Schutkowski M., Shen M., Zhou X.Z., Stukenberg P.T., Rahfeld J., Xu J., Kuang J., Kirschner M.W., Fischer G.et al. Sequence-specific and phosphorylation-dependent proline isomerization. A potential mitotic regulatory mechanism Science. 278:1997;1957-1960.
-
(1997)
Science
, vol.278
, pp. 1957-1960
-
-
Yaffe, M.B.1
Schutkowski, M.2
Shen, M.3
Zhou, X.Z.4
Stukenberg, P.T.5
Rahfeld, J.6
Xu, J.7
Kuang, J.8
Kirschner, M.W.9
Fischer, G.10
-
32
-
-
0035963435
-
Specific protection against breast cancers by cyclin D1 ablation
-
Yu Q., Geng Y., Sicinski P. Specific protection against breast cancers by cyclin D1 ablation. Nature. 411:2001;1017-1021.
-
(2001)
Nature
, vol.411
, pp. 1017-1021
-
-
Yu, Q.1
Geng, Y.2
Sicinski, P.3
-
33
-
-
18644384283
-
The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults
-
Zacchi P., Gostissa M., Uchida T., Salvagno C., Avolio A., Voliniak S., Ronai Z., Blandino G., Schneider C., Del Sal G. The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults. Nature. 419:2002;853-857.
-
(2002)
Nature
, vol.419
, pp. 853-857
-
-
Zacchi, P.1
Gostissa, M.2
Uchida, T.3
Salvagno, C.4
Avolio, A.5
Voliniak, S.6
Ronai, Z.7
Blandino, G.8
Schneider, C.9
Del Sal, G.10
-
34
-
-
18644384688
-
The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response
-
Zheng H., You H., Zhou X.Z., Murray S.A., Uchida T., Wulf G., Gu L., Tang X., Lu K.P., Xiao Z.X.J. The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response. Nature. 419:2002;849-853.
-
(2002)
Nature
, vol.419
, pp. 849-853
-
-
Zheng, H.1
You, H.2
Zhou, X.Z.3
Murray, S.A.4
Uchida, T.5
Wulf, G.6
Gu, L.7
Tang, X.8
Lu, K.P.9
Xiao, Z.X.J.10
-
35
-
-
0033638180
-
Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins
-
Zhou X.Z., Kops O., Werner A., Lu P.J., Shen M., Stoller G., Küllertz G., Stark M., Fischer G., Lu K.P. Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins. Mol. Cell. 6:2000;873-883.
-
(2000)
Mol. Cell
, vol.6
, pp. 873-883
-
-
Zhou, X.Z.1
Kops, O.2
Werner, A.3
Lu, P.J.4
Shen, M.5
Stoller, G.6
Küllertz, G.7
Stark, M.8
Fischer, G.9
Lu, K.P.10
|