메뉴 건너뛰기




Volumn 4, Issue 3, 2003, Pages 175-180

Prolyl isomerase Pin1 as a molecular target for cancer diagnostics and therapeutics

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; CYCLOPHILIN; FK 506 BINDING PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; ISOMERASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOTRANSFERASE; PROLINE; PROLYL ISOMERASE; RAS PROTEIN; SERINE; THREONINE; UNCLASSIFIED DRUG;

EID: 0141457429     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1535-6108(03)00218-6     Document Type: Review
Times cited : (116)

References (35)
  • 2
    • 0035902180 scopus 로고    scopus 로고
    • Oncogenic kinase signalling
    • Blume-Jensen P., Hunter T. Oncogenic kinase signalling. Nature. 411:2001;355-365.
    • (2001) Nature , vol.411 , pp. 355-365
    • Blume-Jensen, P.1    Hunter, T.2
  • 3
    • 0035253619 scopus 로고    scopus 로고
    • Juglone, an inhibitor of the peptidyl-prolyl isomerase Pin1, also directly blocks transcription
    • Chao S.H., Greenleaf A.L., Price D.H. Juglone, an inhibitor of the peptidyl-prolyl isomerase Pin1, also directly blocks transcription. Nucleic Acids Res. 29:2001;767-773.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 767-773
    • Chao, S.H.1    Greenleaf, A.L.2    Price, D.H.3
  • 4
    • 0038518619 scopus 로고    scopus 로고
    • Practical management of patients with chronic myeloid leukemia receiving imatinib
    • Deininger M.W., O'Brien S.G., Ford J.M., Druker B.J. Practical management of patients with chronic myeloid leukemia receiving imatinib. J. Clin. Oncol. 21:2003;1637-1647.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 1637-1647
    • Deininger, M.W.1    O'Brien, S.G.2    Ford, J.M.3    Druker, B.J.4
  • 6
    • 0036463948 scopus 로고    scopus 로고
    • Perspectives on the development of a molecularly targeted agent
    • Druker B.J. Perspectives on the development of a molecularly targeted agent. Cancer Cell. 1:2002;31-36.
    • (2002) Cancer Cell , vol.1 , pp. 31-36
    • Druker, B.J.1
  • 7
    • 0033619755 scopus 로고    scopus 로고
    • Mice lacking Pin1 develop normally, but are defective in entering cell cycle from G(0) arrest
    • Fujimori F., Takahashi K., Uchida C., Uchida T. Mice lacking Pin1 develop normally, but are defective in entering cell cycle from G(0) arrest. Biochem. Biophys. Res. Commun. 265:1999;658-663.
    • (1999) Biochem. Biophys. Res. Commun. , vol.265 , pp. 658-663
    • Fujimori, F.1    Takahashi, K.2    Uchida, C.3    Uchida, T.4
  • 8
    • 0036323564 scopus 로고    scopus 로고
    • The development and clinical use of trastuzumab (Herceptin)
    • Harries M., Smith I. The development and clinical use of trastuzumab (Herceptin). Endocr. Relat. Cancer. 9:2002;75-85.
    • (2002) Endocr. Relat. Cancer , vol.9 , pp. 75-85
    • Harries, M.1    Smith, I.2
  • 10
    • 0032559238 scopus 로고    scopus 로고
    • Prolyl isomerase and nuclear function
    • Hunter T. Prolyl isomerase and nuclear function. Cell. 92:1998;141-143.
    • (1998) Cell , vol.92 , pp. 141-143
    • Hunter, T.1
  • 11
    • 0034636153 scopus 로고    scopus 로고
    • Beta-catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression
    • Lin S.Y., Xia W., Wang J.C., Kwong K.Y., Spohn B., Wen Y., Pestell R.G., Hung M.C. Beta-catenin, a novel prognostic marker for breast cancer. its roles in cyclin D1 expression and cancer progression Proc. Natl. Acad. Sci. USA. 97:2000;4262-4266.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 4262-4266
    • Lin, S.Y.1    Xia, W.2    Wang, J.C.3    Kwong, K.Y.4    Spohn, B.5    Wen, Y.6    Pestell, R.G.7    Hung, M.C.8
  • 14
    • 0029916122 scopus 로고    scopus 로고
    • A human peptidyl-prolyl isomerase essential for regulation of mitosis
    • Lu K.P., Hanes S.D., Hunter T. A human peptidyl-prolyl isomerase essential for regulation of mitosis. Nature. 380:1996;544-547.
    • (1996) Nature , vol.380 , pp. 544-547
    • Lu, K.P.1    Hanes, S.D.2    Hunter, T.3
  • 15
    • 0033600242 scopus 로고    scopus 로고
    • The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein
    • a
    • Lu P.J., Wulf G., Zhou X.Z., Davies P., Lu K.P. The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein. Nature. 399:1999;784-788. a.
    • (1999) Nature , vol.399 , pp. 784-788
    • Lu, P.J.1    Wulf, G.2    Zhou, X.Z.3    Davies, P.4    Lu, K.P.5
  • 16
    • 0040017910 scopus 로고    scopus 로고
    • A function of WW domains as phosphoserine- or phosphothreonine-binding modules
    • b
    • Lu P.J., Zhou X.Z., Shen M., Lu K.P. A function of WW domains as phosphoserine- or phosphothreonine-binding modules. Science. 283:1999;1325-1328. b.
    • (1999) Science , vol.283 , pp. 1325-1328
    • Lu, P.J.1    Zhou, X.Z.2    Shen, M.3    Lu, K.P.4
  • 17
    • 0037169479 scopus 로고    scopus 로고
    • Critical role of WW domain phosphorylation in regulating its phosphoserine-binding activity and the Pin1 function
    • a
    • Lu P.J., Zhou X.Z., Liou Y.C., Noel J.P., Lu K.P. Critical role of WW domain phosphorylation in regulating its phosphoserine-binding activity and the Pin1 function. J. Biol. Chem. 277:2002;2381-2384. a.
    • (2002) J. Biol. Chem. , vol.277 , pp. 2381-2384
    • Lu, P.J.1    Zhou, X.Z.2    Liou, Y.C.3    Noel, J.P.4    Lu, K.P.5
  • 18
    • 0036535975 scopus 로고    scopus 로고
    • Pinning down the proline-directed phosphorylation signaling
    • b
    • Lu K.P., Liou Y.C., Zhou X.Z. Pinning down the proline-directed phosphorylation signaling. Trends Cell Biol. 12:2002;164-172. b.
    • (2002) Trends Cell Biol. , vol.12 , pp. 164-172
    • Lu, K.P.1    Liou, Y.C.2    Zhou, X.Z.3
  • 19
    • 0035063183 scopus 로고    scopus 로고
    • The Rb/E2F pathway and cancer
    • Nevins J.R. The Rb/E2F pathway and cancer. Hum. Mol. Genet. 10:2001;699-703.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 699-703
    • Nevins, J.R.1
  • 20
    • 0008233581 scopus 로고    scopus 로고
    • Structural and functional analysis of the mitotic peptidyl-prolyl isomerase Pin1 suggests that substrate recognition is phosphorylation dependent
    • Ranganathan R., Lu K.P., Hunter T., Noel J.P. Structural and functional analysis of the mitotic peptidyl-prolyl isomerase Pin1 suggests that substrate recognition is phosphorylation dependent. Cell. 89:1997;875-886.
    • (1997) Cell , vol.89 , pp. 875-886
    • Ranganathan, R.1    Lu, K.P.2    Hunter, T.3    Noel, J.P.4
  • 22
    • 0034840950 scopus 로고    scopus 로고
    • Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC
    • Ryo A., Nakamura N., Wulf G., Liou Y.C., Lu K.P. Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC. Nat. Cell Biol. 3:2001;793-801.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 793-801
    • Ryo, A.1    Nakamura, N.2    Wulf, G.3    Liou, Y.C.4    Lu, K.P.5
  • 23
    • 0036315162 scopus 로고    scopus 로고
    • Pin1 is an E2F target gene essential for the Neu/Ras-induced transformation of mammary epithelial cells
    • Ryo A., Liou Y.C., Wulf G., Nakamura N., Lee S.W., Lu K.P. Pin1 is an E2F target gene essential for the Neu/Ras-induced transformation of mammary epithelial cells. Mol. Cell. Biol. 22:2002;5281-5295.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5281-5295
    • Ryo, A.1    Liou, Y.C.2    Wulf, G.3    Nakamura, N.4    Lee, S.W.5    Lu, K.P.6
  • 24
    • 0037351048 scopus 로고    scopus 로고
    • Prolyl isomerase Pin1, a catalyst for oncogenesis and a potential anticancer target
    • Ryo A., Liou Y.C., Lu K.P., Wulf G. Prolyl isomerase Pin1, a catalyst for oncogenesis and a potential anticancer target. J. Cell Sci. 116:2003;773-783.
    • (2003) J. Cell Sci. , vol.116 , pp. 773-783
    • Ryo, A.1    Liou, Y.C.2    Lu, K.P.3    Wulf, G.4
  • 25
    • 0032031634 scopus 로고    scopus 로고
    • The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins
    • Shen M., Stukenberg P.T., Kirschner M.W., Lu K.P. The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins. Genes Dev. 12:1998;706-720.
    • (1998) Genes Dev. , vol.12 , pp. 706-720
    • Shen, M.1    Stukenberg, P.T.2    Kirschner, M.W.3    Lu, K.P.4
  • 28
    • 0342322902 scopus 로고    scopus 로고
    • Evidence that the substrate backbone conformation is critical to phosphorylation by p42 MAP kinase
    • Weiwad M., Kullertz G., Schutkowski M., Fischer G. Evidence that the substrate backbone conformation is critical to phosphorylation by p42 MAP kinase. FEBS Lett. 478:2000;39-42.
    • (2000) FEBS Lett. , vol.478 , pp. 39-42
    • Weiwad, M.1    Kullertz, G.2    Schutkowski, M.3    Fischer, G.4
  • 29
    • 0035796405 scopus 로고    scopus 로고
    • Pin1 is overexpressed in breast cancer and potentiates the transcriptional activity of phosphorylated c-Jun towards the cyclin D1 gene
    • Wulf G.M., Ryo A., Wulf G.G., Lee S.W., Niu T., Lu K.P. Pin1 is overexpressed in breast cancer and potentiates the transcriptional activity of phosphorylated c-Jun towards the cyclin D1 gene. EMBO J. 20:2001;3459-3472.
    • (2001) EMBO J. , vol.20 , pp. 3459-3472
    • Wulf, G.M.1    Ryo, A.2    Wulf, G.G.3    Lee, S.W.4    Niu, T.5    Lu, K.P.6
  • 30
    • 0037073713 scopus 로고    scopus 로고
    • Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage
    • Wulf G.M., Liou Y.C., Ryo A., Lee S.W., Lu K.P. Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage. J. Biol. Chem. 277:2002;47976-47979.
    • (2002) J. Biol. Chem. , vol.277 , pp. 47976-47979
    • Wulf, G.M.1    Liou, Y.C.2    Ryo, A.3    Lee, S.W.4    Lu, K.P.5
  • 32
    • 0035963435 scopus 로고    scopus 로고
    • Specific protection against breast cancers by cyclin D1 ablation
    • Yu Q., Geng Y., Sicinski P. Specific protection against breast cancers by cyclin D1 ablation. Nature. 411:2001;1017-1021.
    • (2001) Nature , vol.411 , pp. 1017-1021
    • Yu, Q.1    Geng, Y.2    Sicinski, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.