-
1
-
-
46349106355
-
Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain
-
DOI 10.1136/gut.2007.138982
-
Akbar A, Yiangou Y, Facer P, Walters JR, Anand P, Ghosh S (2008) Increased capsaicin receptor TRPV1 expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain. Gut. doi:10.1136/gut.2007. 138982 (Pubitemid 351919527)
-
(2008)
Gut
, vol.57
, Issue.7
, pp. 923-929
-
-
Akbar, A.1
Yiangou, Y.2
Facer, P.3
Walters, J.R.F.4
Anand, P.5
Ghosh, S.6
-
2
-
-
2342666609
-
Transient receptor potential vanilloid 4 is essential in chemotherapy-induced neuropathic pain in the rat
-
Alessandri-Haber N, Dina OA, Yeh JJ, Parada CA, Reichling DB, Levine JD (2004) Transient receptor potential vanilloid 4 is essential in chemotherapy-induced neuropathic pain in the rat. J Neurosci 24:4444-4452
-
(2004)
J Neurosci
, vol.24
, pp. 4444-4452
-
-
Alessandri-Haber, N.1
Dina, O.A.2
Yeh, J.J.3
Parada, C.A.4
Reichling, D.B.5
Levine, J.D.6
-
3
-
-
33645557094
-
A transient receptor potential vanilloid 4-dependent mechanism of hyperalgesia is engaged by concerted action of inflammatory mediators
-
Alessandri-Haber N, Dina OA, Joseph EK, Reichling D, Levine JD (2006) A transient receptor potential vanilloid 4-dependent mechanism of hyperalgesia is engaged by concerted action of inflammatory mediators. J Neurosci 26:3864-3874
-
(2006)
J Neurosci
, vol.26
, pp. 3864-3874
-
-
Alessandri-Haber, N.1
Dina, O.A.2
Joseph, E.K.3
Reichling, D.4
Levine, J.D.5
-
4
-
-
38749148787
-
Interaction of transient receptor potential vanilloid 4, integrin, and SRC tyrosine kinase in mechanical hyperalgesia
-
Alessandri-Haber N, Dina OA, Joseph EK, Reichling DB, Levine JD (2008) Interaction of transient receptor potential vanilloid 4, integrin, and SRC tyrosine kinase in mechanical hyperalgesia. J Neurosci 28:1046-1057
-
(2008)
J Neurosci
, vol.28
, pp. 1046-1057
-
-
Alessandri-Haber, N.1
Dina, O.A.2
Joseph, E.K.3
Reichling, D.B.4
Levine, J.D.5
-
5
-
-
1842475312
-
Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin
-
Bandell M, Story GM, Hwang SW, Viswanath V, Eid SR, Petrus MJ, Earley TJ, Patapoutian A (2004) Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron 41:849-857
-
(2004)
Neuron
, vol.41
, pp. 849-857
-
-
Bandell, M.1
Story, G.M.2
Hwang, S.W.3
Viswanath, V.4
Eid, S.R.5
Petrus, M.J.6
Earley, T.J.7
Patapoutian, A.8
-
6
-
-
34548637630
-
Transient receptor potential V2 expressed in sensory neurons is activated by probenecid
-
Bang S, Kim KY, Yoo S, Lee SH, Hwang SW (2007) Transient receptor potential V2 expressed in sensory neurons is activated by probenecid. Neurosci Lett 425:120-125
-
(2007)
Neurosci Lett
, vol.425
, pp. 120-125
-
-
Bang, S.1
Kim, K.Y.2
Yoo, S.3
Lee, S.H.4
Hwang, S.W.5
-
7
-
-
24744446008
-
Pungent products from garlic activate the sensory ion channel TRPA1
-
Bautista DM, Movahed P, Hinman A, Axelsson HE, Sterner O, Hogestatt ED, Julius D, Jordt SE, Zygmunt PM (2005) Pungent products from garlic activate the sensory ion channel TRPA1. Proc Natl Acad Sci USA 102:12248-12252
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 12248-12252
-
-
Bautista, D.M.1
Movahed, P.2
Hinman, A.3
Axelsson, H.E.4
Sterner, O.5
Hogestatt, E.D.6
Julius, D.7
Jordt, S.E.8
Zygmunt, P.M.9
-
8
-
-
33646045075
-
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents
-
Bautista DM, Jordt SE, Nikai T, Tsuruda PR, Read AJ, Poblete J, Yamoah EN, Basbaum AI, Julius D (2006) TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents. Cell 124:1269-1282
-
(2006)
Cell
, vol.124
, pp. 1269-1282
-
-
Bautista, D.M.1
Jordt, S.E.2
Nikai, T.3
Tsuruda, P.R.4
Read, A.J.5
Poblete, J.6
Yamoah, E.N.7
Basbaum, A.I.8
Julius, D.9
-
9
-
-
34447542435
-
The menthol receptor TRPM8 is the principal detector of environmental cold
-
Bautista DM, Siemens J, Glazer JM, Tsuruda PR, Basbaum AI, Stucky CL, Jordt SE, Julius D (2007) The menthol receptor TRPM8 is the principal detector of environmental cold. Nature 448:204-208
-
(2007)
Nature
, vol.448
, pp. 204-208
-
-
Bautista, D.M.1
Siemens, J.2
Glazer, J.M.3
Tsuruda, P.R.4
Basbaum, A.I.5
Stucky, C.L.6
Jordt, S.E.7
Julius, D.8
-
10
-
-
1842453817
-
Characterization of the mouse coldmenthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay
-
Behrendt HJ, Germann T, Gillen C, Hatt H, Jostock R (2004) Characterization of the mouse coldmenthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. Br J Pharmacol 141:737-745
-
(2004)
Br J Pharmacol
, vol.141
, pp. 737-745
-
-
Behrendt, H.J.1
Germann, T.2
Gillen, C.3
Hatt, H.4
Jostock, R.5
-
11
-
-
0026767602
-
Capsazepine: A competitive antagonist of the sensory neurone excitant capsaicin
-
Bevan S, Hothi S, Hughes G, James IF, Rang HP, Shah K, Walpole CS, Yeats JC (1992) Capsazepine: a competitive antagonist of the sensory neurone excitant capsaicin. Br J Pharmacol 107:544-552
-
(1992)
Br J Pharmacol
, vol.107
, pp. 544-552
-
-
Bevan, S.1
Hothi, S.2
Hughes, G.3
James, I.F.4
Rang, H.P.5
Shah, K.6
Walpole, C.S.7
Yeats, J.C.8
-
12
-
-
34548814494
-
[3H]A-778317 [1-((R)-5-tert-butyl-indan-1-yl)-3-isoquinolin- 5-yl-urea]: A novel, stereoselective, high-affinity antagonist is a useful radioligand for the human transient receptor potential vanilloid-1 (TRPV1) receptor
-
BianchiBR,ElKouhenRet al (2007) [3H]A-778317 [1-((R)-5-tert-butyl-indan- 1-yl)-3-isoquinolin- 5-yl-urea]: a novel, stereoselective, high-affinity antagonist is a useful radioligand for the human transient receptor potential vanilloid-1 (TRPV1) receptor. J Pharmacol Exp Ther 323:285-293
-
(2007)
J Pharmacol Exp Ther
, vol.323
, pp. 285-293
-
-
Bianchi, B.R.1
Elkouhen, R.2
-
13
-
-
34748877218
-
Characterisation of TRPM8 as a pharmacophore receptor
-
Bodding M, Wissenbach U, Flockerzi V (2007) Characterisation of TRPM8 as a pharmacophore receptor. Cell Calcium 42:618-628
-
(2007)
Cell Calcium
, vol.42
, pp. 618-628
-
-
Bodding, M.1
Wissenbach, U.2
Flockerzi, V.3
-
14
-
-
0035823409
-
Peripheral capsaicin receptors increase in the inflamed rat hindpaw: A possible mechanism for peripheral sensitization
-
Carlton SM, Coggeshall RE (2001) Peripheral capsaicin receptors increase in the inflamed rat hindpaw: a possible mechanism for peripheral sensitization. Neurosci Lett 310:53-56
-
(2001)
Neurosci Lett
, vol.310
, pp. 53-56
-
-
Carlton, S.M.1
Coggeshall, R.E.2
-
15
-
-
0030777012
-
The capsaicin receptor: A heat-activated ion channel in the pain pathway
-
Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D (1997) The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389:816-824
-
(1997)
Nature
, vol.389
, pp. 816-824
-
-
Caterina, M.J.1
Schumacher, M.A.2
Tominaga, M.3
Rosen, T.A.4
Levine, J.D.5
Julius, D.6
-
16
-
-
0033119629
-
A capsaicin-receptor homologue with a high threshold for noxious heat
-
Caterina MJ, Rosen TA, Tominaga M, Brake AJ, Julius D (1999) A capsaicin-receptor homologue with a high threshold for noxious heat. Nature 398:436-441
-
(1999)
Nature
, vol.398
, pp. 436-441
-
-
Caterina, M.J.1
Rosen, T.A.2
Tominaga, M.3
Brake, A.J.4
Julius, D.5
-
17
-
-
0034646740
-
Impaired nociception and pain sensation in mice lacking the capsaicin receptor
-
Caterina MJ, Leffler A, Malmberg AB, Martin WJ, Trafton J, Petersen-Zeitz KR, Koltzenburg M, Basbaum AI, Julius D (2000) Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science 288:306-313
-
(2000)
Science
, vol.288
, pp. 306-313
-
-
Caterina, M.J.1
Leffler, A.2
Malmberg, A.B.3
Martin, W.J.4
Trafton, J.5
Petersen-Zeitz, K.R.6
Koltzenburg, M.7
Basbaum, A.I.8
Julius, D.9
-
18
-
-
33746888290
-
Transient receptor potential vanilloid 1-immunopositive neurons in the mouse are more prevalent within colon afferents compared to skin and muscle afferents
-
Christianson JA, McIlwrath SL, Koerber HR, Davis BM (2006) Transient receptor potential vanilloid 1-immunopositive neurons in the mouse are more prevalent within colon afferents compared to skin and muscle afferents. Neuroscience 140:247-257
-
(2006)
Neuroscience
, vol.140
, pp. 247-257
-
-
Christianson, J.A.1
McIlwrath, S.L.2
Koerber, H.R.3
Davis, B.M.4
-
19
-
-
33749050585
-
Silencing of vanilloid receptor TRPV1 by RNAi reduces neuropathic and visceral pain in vivo
-
Christoph T, Grunweller A et al (2006) Silencing of vanilloid receptor TRPV1 by RNAi reduces neuropathic and visceral pain in vivo. Biochem Biophys Res Commun 350:238-243
-
(2006)
Biochem Biophys Res Commun
, vol.350
, pp. 238-243
-
-
Christoph, T.1
Grunweller, A.2
-
20
-
-
33845343959
-
Antinociceptive effect of antisense oligonucleotides against the vanilloid receptor VR1/TRPV1
-
Christoph T, Gillen C et al (2007) Antinociceptive effect of antisense oligonucleotides against the vanilloid receptor VR1/TRPV1. Neurochem Int 50:281-290
-
(2007)
Neurochem Int
, vol.50
, pp. 281-290
-
-
Christoph, T.1
Gillen, C.2
-
21
-
-
39749089798
-
Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice
-
Christoph T, Bahrenberg G et al (2008) Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice. Mol Cell Neurosci 37:579-589
-
(2008)
Mol Cell Neurosci
, vol.37
, pp. 579-589
-
-
Christoph, T.1
Bahrenberg, G.2
-
22
-
-
2642568616
-
2-Aminoethoxydiphenyl borate activates and sensitizes the heat-gated ion channel TRPV3
-
Chung MK, Lee H, Mizuno A, Suzuki M, Caterina MJ (2004) 2-Aminoethoxydiphenyl borate activates and sensitizes the heat-gated ion channel TRPV3. J Neurosci 24:5177-5182
-
(2004)
J Neurosci
, vol.24
, pp. 5177-5182
-
-
Chung, M.K.1
Lee, H.2
Mizuno, A.3
Suzuki, M.4
Caterina, M.J.5
-
23
-
-
34547864302
-
The transient receptor potential vanilloid-responsive 1 and 4 cation channels: Role in neuronal osmosensing and renal physiology
-
Cohen DM (2007) The transient receptor potential vanilloid-responsive 1 and 4 cation channels: role in neuronal osmosensing and renal physiology. Curr Opin Nephrol Hypertens 16:451-458
-
(2007)
Curr Opin Nephrol Hypertens
, vol.16
, pp. 451-458
-
-
Cohen, D.M.1
-
24
-
-
34247472646
-
Attenuated cold sensitivity in TRPM8 null mice
-
Colburn RW, Lubin ML et al (2007) Attenuated cold sensitivity in TRPM8 null mice. Neuron 54:379-386
-
(2007)
Neuron
, vol.54
, pp. 379-386
-
-
Colburn, R.W.1
Lubin, M.L.2
-
25
-
-
10644290199
-
TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells
-
Corey DP, Garcia-Anoveros J et al (2004) TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells. Nature 432:723-730
-
(2004)
Nature
, vol.432
, pp. 723-730
-
-
Corey, D.P.1
Garcia-Anoveros, J.2
-
26
-
-
0034816158
-
The tissue distribution and functional characterization of human VR1
-
Cortright DN, Crandall M, Sanchez JF, Zou T, Krause JE, White G (2001) The tissue distribution and functional characterization of human VR1. Biochem Biophys Res Commun 281:1183-1189
-
(2001)
Biochem Biophys Res Commun
, vol.281
, pp. 1183-1189
-
-
Cortright, D.N.1
Crandall, M.2
Sanchez, J.F.3
Zou, T.4
Krause, J.E.5
White, G.6
-
27
-
-
0036291431
-
Activation of protein kinase C sensitizes human VR1 to capsaicin and to moderate decreases in pH at physiological temperatures in xenopus oocytes
-
Crandall M, Kwash J, Yu W, White G (2002) Activation of protein kinase C sensitizes human VR1 to capsaicin and to moderate decreases in pH at physiological temperatures in Xenopus oocytes. Pain 98:109-117
-
(2002)
Pain
, vol.98
, pp. 109-117
-
-
Crandall, M.1
Kwash, J.2
Yu, W.3
White, G.4
-
28
-
-
33748680717
-
TRPV1 receptors in the CNS play a key role in broad-spectrum analgesia of TRPV1 antagonists
-
Cui M, Honore P et al (2006) TRPV1 receptors in the CNS play a key role in broad-spectrum analgesia of TRPV1 antagonists. J Neurosci 26:9385-9393
-
(2006)
J Neurosci
, vol.26
, pp. 9385-9393
-
-
Cui, M.1
Honore, P.2
-
29
-
-
44449092146
-
Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3
-
D'Hoedt D, Owsianik G, Prenen J, Cuajungco MP, Grimm C, Heller S, Voets T, Nilius B (2008) Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3. J Biol Chem 283:6272-6280
-
(2008)
J Biol Chem
, vol.283
, pp. 6272-6280
-
-
D'Hoedt, D.1
Owsianik, G.2
Prenen, J.3
Cuajungco, M.P.4
Grimm, C.5
Heller, S.6
Voets, T.7
Nilius, B.8
-
30
-
-
34447121851
-
Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain
-
Dai Y, Wang S et al (2007) Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain. J Clin Invest 117:1979-1987
-
(2007)
J Clin Invest
, vol.117
, pp. 1979-1987
-
-
Dai, Y.1
Wang, S.2
-
31
-
-
0034636441
-
Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia
-
Davis JB, Gray J et al (2000) Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. Nature 405:183-187
-
(2000)
Nature
, vol.405
, pp. 183-187
-
-
Davis, J.B.1
Gray, J.2
-
32
-
-
0348142491
-
Identification and characterization of a novel human vanilloid receptor-like protein, VRL-2
-
Delany NS, Hurle M et al (2001) Identification and characterization of a novel human vanilloid receptor-like protein, VRL-2. Physiol Genomics 4:165-174
-
(2001)
Physiol Genomics
, vol.4
, pp. 165-174
-
-
Delany, N.S.1
Hurle, M.2
-
34
-
-
34247487011
-
TRPM8 is required for cold sensation in mice
-
Dhaka A, Murray AN, Mathur J, Earley TJ, Petrus MJ, Patapoutian A (2007) TRPM8 is required for cold sensation in mice. Neuron 54:371-378
-
(2007)
Neuron
, vol.54
, pp. 371-378
-
-
Dhaka, A.1
Murray, A.N.2
Mathur, J.3
Earley, T.J.4
Petrus, M.J.5
Patapoutian, A.6
-
35
-
-
34347256804
-
NGF up-regulates TRPA1: Implications for orofacial pain
-
Diogenes A, Akopian AN, Hargreaves KM (2007) NGF up-regulates TRPA1: implications for orofacial pain. J Dent Res 86:550-555
-
(2007)
J Dent Res
, vol.86
, pp. 550-555
-
-
Diogenes, A.1
Akopian, A.N.2
Hargreaves, K.M.3
-
36
-
-
34250379970
-
Transient receptor potential channel A1 is directly gated by calcium ions
-
Doerner JF, Gisselmann G, Hatt H, Wetzel CH (2007) Transient receptor potential channel A1 is directly gated by calcium ions. J Biol Chem 282:13180-13189
-
(2007)
J Biol Chem
, vol.282
, pp. 13180-13189
-
-
Doerner, J.F.1
Gisselmann, G.2
Hatt, H.3
Wetzel, C.H.4
-
37
-
-
34250857978
-
Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy
-
Facer P, Casula MA, Smith GD, Benham CD, Chessell IP, Bountra C, Sinisi M, Birch R, Anand P (2007) Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy. BMC Neurol 7:11
-
(2007)
BMC Neurol
, vol.7
, pp. 11
-
-
Facer, P.1
Casula, M.A.2
Smith, G.D.3
Benham, C.D.4
Chessell, I.P.5
Bountra, C.6
Sinisi, M.7
Birch, R.8
Anand, P.9
-
38
-
-
34249693460
-
Increased TRPA1, TRPM8, and TRPV2 expression in dorsal root ganglia by nerve injury
-
Frederick J, Buck ME, Matson DJ, Cortright DN (2007) Increased TRPA1, TRPM8, and TRPV2 expression in dorsal root ganglia by nerve injury. Biochem Biophys Res Commun 358:1058-1064
-
(2007)
Biochem Biophys Res Commun
, vol.358
, pp. 1058-1064
-
-
Frederick, J.1
Buck, M.E.2
Matson, D.J.3
Cortright, D.N.4
-
39
-
-
36049028276
-
Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding
-
Gevaert T, Vriens J et al (2007) Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding. J Clin Invest 117:3453-3462
-
(2007)
J Clin Invest
, vol.117
, pp. 3453-3462
-
-
Gevaert, T.1
Vriens, J.2
-
40
-
-
40249111593
-
TRPV1 channels mediate long-term depression at synapses on hippocampal interneurons
-
Gibson HE, Edwards JG, Page RS, Van Hook MJ, Kauer JA (2008) TRPV1 channels mediate long-term depression at synapses on hippocampal interneurons. Neuron 57:746-759
-
(2008)
Neuron
, vol.57
, pp. 746-759
-
-
Gibson, H.E.1
Edwards, J.G.2
Page, R.S.3
Van Hook, M.J.4
Kauer, J.A.5
-
41
-
-
0036703646
-
Heat-evoked activation of the ion channel, TRPV4
-
Guler AD, Lee H, Iida T, Shimizu I, Tominaga M, Caterina M (2002) Heat-evoked activation of the ion channel, TRPV4. J Neurosci 22:6408-6414
-
(2002)
J Neurosci
, vol.22
, pp. 6408-6414
-
-
Guler, A.D.1
Lee, H.2
Iida, T.3
Shimizu, I.4
Tominaga, M.5
Caterina, M.6
-
42
-
-
0025743390
-
Discharge patterns of human C-fibers induced by itching and burning stimuli
-
Handwerker HO, Forster C, Kirchhoff C (1991) Discharge patterns of human C-fibers induced by itching and burning stimuli. J Neurophysiol 66:307-315
-
(1991)
J Neurophysiol
, vol.66
, pp. 307-315
-
-
Handwerker, H.O.1
Forster, C.2
Kirchhoff, C.3
-
44
-
-
4143090688
-
2-Aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3
-
Hu HZ, Gu Q, Wang C, Colton CK, Tang J, Kinoshita-Kawada M, Lee LY, Wood JD, Zhu MX (2004) 2-Aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3. J Biol Chem 279:35741-35748
-
(2004)
J Biol Chem
, vol.279
, pp. 35741-35748
-
-
Hu, H.Z.1
Gu, Q.2
Wang, C.3
Colton, C.K.4
Tang, J.5
Kinoshita-Kawada, M.6
Lee, L.Y.7
Wood, J.D.8
Zhu, M.X.9
-
45
-
-
33744916763
-
Potentiation of TRPV3 channel function by unsaturated fatty acids
-
Hu HZ, Xiao R, Wang C, Gao N, Colton CK, Wood JD, Zhu MX (2006) Potentiation of TRPV3 channel function by unsaturated fatty acids. J Cell Physiol 208:201-212
-
(2006)
J Cell Physiol
, vol.208
, pp. 201-212
-
-
Hu, H.Z.1
Xiao, R.2
Wang, C.3
Gao, N.4
Colton, C.K.5
Wood, J.D.6
Zhu, M.X.7
-
46
-
-
1642430679
-
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
-
Jordt SE, Bautista DM, Chuang HH, McKemy DD, Zygmunt PM, Hogestatt ED, Meng ID, Julius D (2004) Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature 427:260-265
-
(2004)
Nature
, vol.427
, pp. 260-265
-
-
Jordt, S.E.1
Bautista, D.M.2
Chuang, H.H.3
McKemy, D.D.4
Zygmunt, P.M.5
Hogestatt, E.D.6
Meng, I.D.7
Julius, D.8
-
47
-
-
0033162068
-
Translocation of a calciumpermeable cation channel induced by insulin-like growth factor-I
-
Kanzaki M, Zhang YQ, Mashima H, Li L, Shibata H, Kojima I (1999) Translocation of a calciumpermeable cation channel induced by insulin-like growth factor-I. Nat Cell Biol 1:165-170
-
(1999)
Nat Cell Biol
, vol.1
, pp. 165-170
-
-
Kanzaki, M.1
Zhang, Y.Q.2
Mashima, H.3
Li, L.4
Shibata, H.5
Kojima, I.6
-
48
-
-
34249990908
-
RNA interferencemediated knock-down of transient receptor potential vanilloid 1 prevents forepaw inflammatory hyperalgesia in rat
-
Kasama S, Kawakubo M, Suzuki T, Nishizawa T, Ishida A, Nakayama J (2007) RNA interferencemediated knock-down of transient receptor potential vanilloid 1 prevents forepaw inflammatory hyperalgesia in rat. Eur J Neurosci 25:2956-2963
-
(2007)
Eur J Neurosci
, vol.25
, pp. 2956-2963
-
-
Kasama, S.1
Kawakubo, M.2
Suzuki, T.3
Nishizawa, T.4
Ishida, A.5
Nakayama, J.6
-
49
-
-
33746083982
-
Antisense knock down of TRPA1, but not TRPM8, alleviates cold hyperalgesia after spinal nerve ligation in rats
-
Katsura H, Obata K et al (2006) Antisense knock down of TRPA1, but not TRPM8, alleviates cold hyperalgesia after spinal nerve ligation in rats. Exp Neurol 200:112-123
-
(2006)
Exp Neurol
, vol.200
, pp. 112-123
-
-
Katsura, H.1
Obata, K.2
-
50
-
-
34247536405
-
Caenorhabditis elegans TRPA-1 functions in mechanosensation
-
Kindt KS, Viswanath V, Macpherson L, Quast K, Hu H, Patapoutian A, Schafer WR (2007) Caenorhabditis elegans TRPA-1 functions in mechanosensation. Nat Neurosci 10:568-577
-
(2007)
Nat Neurosci
, vol.10
, pp. 568-577
-
-
Kindt, K.S.1
Viswanath, V.2
MacPherson, L.3
Quast, K.4
Hu, H.5
Patapoutian, A.6
Schafer, W.R.7
-
51
-
-
33749013892
-
A polyclonal antibody to the pre-pore loop of TRPV1 blocks channel activation
-
Klionsky L, Tamir R et al (2006) A polyclonal antibody to the pre-pore loop of TRPV1 blocks channel activation. J Pharmacol Exp Ther 319:192-198
-
(2006)
J Pharmacol Exp Ther
, vol.319
, pp. 192-198
-
-
Klionsky, L.1
Tamir, R.2
-
52
-
-
1542329731
-
Activation of bronchopulmonary vagal afferent nerves with bradykinin, acid and vanilloid receptor agonists in wild-type and TRPV1-/- mice
-
Kollarik M, Undem BJ (2004) Activation of bronchopulmonary vagal afferent nerves with bradykinin, acid and vanilloid receptor agonists in wild-type and TRPV1-/- mice. J Physiol 555:115-123
-
(2004)
J Physiol
, vol.555
, pp. 115-123
-
-
Kollarik, M.1
Undem, B.J.2
-
53
-
-
0026749526
-
Dynamic and static components of mechanical hyperalgesia in human hairy skin
-
Koltzenburg M, Lundberg LE, Torebjork HE (1992) Dynamic and static components of mechanical hyperalgesia in human hairy skin. Pain 51:207-219
-
(1992)
Pain
, vol.51
, pp. 207-219
-
-
Koltzenburg, M.1
Lundberg, L.E.2
Torebjork, H.E.3
-
54
-
-
12544259812
-
Transient receptor potential ion channels as targets for the discovery of pain therapeutics
-
Krause JE, Chenard BL, Cortright DN (2005) Transient receptor potential ion channels as targets for the discovery of pain therapeutics. Curr Opin Investig Drugs 6:48-57
-
(2005)
Curr Opin Investig Drugs
, vol.6
, pp. 48-57
-
-
Krause, J.E.1
Chenard, B.L.2
Cortright, D.N.3
-
55
-
-
33646061333
-
TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for haircell transduction
-
Kwan KY, Allchorne AJ, Vollrath MA, Christensen AP, Zhang DS, Woolf CJ, Corey DP (2006) TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for haircell transduction. Neuron 50:277-289
-
(2006)
Neuron
, vol.50
, pp. 277-289
-
-
Kwan, K.Y.1
Allchorne, A.J.2
Vollrath, M.A.3
Christensen, A.P.4
Zhang, D.S.5
Woolf, C.J.6
Corey, D.P.7
-
56
-
-
13944255381
-
Altered thermal selection behavior in mice lacking transient receptor potential vanilloid 4
-
Lee H, Iida T, Mizuno A, Suzuki M, Caterina MJ (2005) Altered thermal selection behavior in mice lacking transient receptor potential vanilloid 4. J Neurosci 25:1304-1310
-
(2005)
J Neurosci
, vol.25
, pp. 1304-1310
-
-
Lee, H.1
Iida, T.2
Mizuno, A.3
Suzuki, M.4
Caterina, M.J.5
-
57
-
-
45749092572
-
Antihyperalgesic effects of AMG8562, a novel vanilloid receptor TRPV1 modulator that does not cause hyperthermia in rats
-
Lehto S, Tamir R et al (2008) Antihyperalgesic effects of AMG8562, a novel vanilloid receptor TRPV1 modulator that does not cause hyperthermia in rats. J Pharmacol Exp Ther 326:218-229
-
(2008)
J Pharmacol Exp Ther
, vol.326
, pp. 218-229
-
-
Lehto, S.1
Tamir, R.2
-
58
-
-
1242296878
-
Immunoreactive TRPV-2 (VRL-1), a capsaicin receptor homolog, in the spinal cord of the rat
-
Lewinter RD, Skinner K, Julius D, Basbaum AI (2004) Immunoreactive TRPV-2 (VRL-1), a capsaicin receptor homolog, in the spinal cord of the rat. J Comp Neurol 470:400-408
-
(2004)
J Comp Neurol
, vol.470
, pp. 400-408
-
-
Lewinter, R.D.1
Skinner, K.2
Julius, D.3
Basbaum, A.I.4
-
59
-
-
38049058793
-
Dense transient receptor potential cation channel, vanilloid family, type 2 (TRPV2) immunoreactivity defines a subset of motoneurons in the dorsal lateral nucleus of the spinal cord, the nucleus ambiguus and the trigeminal motor nucleus in rat
-
Lewinter RD, Scherrer G, Basbaum AI (2008) Dense transient receptor potential cation channel, vanilloid family, type 2 (TRPV2) immunoreactivity defines a subset of motoneurons in the dorsal lateral nucleus of the spinal cord, the nucleus ambiguus and the trigeminal motor nucleus in rat. Neuroscience 151:164-173
-
(2008)
Neuroscience
, vol.151
, pp. 164-173
-
-
Lewinter, R.D.1
Scherrer, G.2
Basbaum, A.I.3
-
60
-
-
0034721648
-
Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor
-
Liedtke W, Choe Y, Marti-Renom MA, Bell AM, Denis CS, Sali A, Hudspeth AJ, Friedman JM, Heller S (2000) Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor. Cell 103:525-535
-
(2000)
Cell
, vol.103
, pp. 525-535
-
-
Liedtke, W.1
Choe, Y.2
Marti-Renom, M.A.3
Bell, A.M.4
Denis, C.S.5
Sali, A.6
Hudspeth, A.J.7
Friedman, J.M.8
Heller, S.9
-
61
-
-
0345659198
-
Abnormal osmotic regulation in TRPV4-/- mice
-
Liedtke W, Friedman JM (2003) Abnormal osmotic regulation in TRPV4-/- mice. Proc Natl Acad Sci USA 100:13698-13703
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 13698-13703
-
-
Liedtke, W.1
Friedman, J.M.2
-
62
-
-
14044261739
-
Functional control of cold- and menthol-sensitive TRPM8 ion channels by phosphatidylinositol 4,5-bisphosphate
-
Liu B, Qin F (2005) Functional control of cold- and menthol-sensitive TRPM8 ion channels by phosphatidylinositol 4,5-bisphosphate. J Neurosci 25:1674-1681
-
(2005)
J Neurosci
, vol.25
, pp. 1674-1681
-
-
Liu, B.1
Qin, F.2
-
63
-
-
34347354387
-
Dual regulation of TRPV1 by phosphoinositides
-
Lukacs V, Thyagarajan B, Varnai P, Balla A, Balla T, Rohacs T (2007) Dual regulation of TRPV1 by phosphoinositides. J Neurosci 27:7070-7080
-
(2007)
J Neurosci
, vol.27
, pp. 7070-7080
-
-
Lukacs, V.1
Thyagarajan, B.2
Varnai, P.3
Balla, A.4
Balla, T.5
Rohacs, T.6
-
64
-
-
20144371097
-
The pungency of garlic: Activation of TRPA1 and TRPV1 in response to allicin
-
Macpherson LJ, Geierstanger BH, Viswanath V, Bandell M, Eid SR, Hwang S, Patapoutian A (2005) The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin. Curr Biol 15:929-934
-
(2005)
Curr Biol
, vol.15
, pp. 929-934
-
-
MacPherson, L.J.1
Geierstanger, B.H.2
Viswanath, V.3
Bandell, M.4
Eid, S.R.5
Hwang, S.6
Patapoutian, A.7
-
65
-
-
33746716158
-
More than cool: Promiscuous relationships of menthol and other sensory compounds
-
Macpherson LJ, Hwang SW, Miyamoto T, Dubin AE, Patapoutian A, Story GM (2006) More than cool: Promiscuous relationships of menthol and other sensory compounds. Mol Cell Neurosci 32(4):335-343
-
(2006)
Mol Cell Neurosci
, vol.32
, Issue.4
, pp. 335-343
-
-
MacPherson, L.J.1
Hwang, S.W.2
Miyamoto, T.3
Dubin, A.E.4
Patapoutian, A.5
Story, G.M.6
-
66
-
-
33846692923
-
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
-
Macpherson LJ, Dubin AE, Evans MJ, Marr F, Schultz PG, Cravatt BF, Patapoutian A (2007a) Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines. Nature 445:541-545
-
(2007)
Nature
, vol.445
, pp. 541-545
-
-
MacPherson, L.J.1
Dubin, A.E.2
Evans, M.J.3
Marr, F.4
Schultz, P.G.5
Cravatt, B.F.6
Patapoutian, A.7
-
67
-
-
35449008419
-
An ion channel essential for sensing chemical damage
-
Macpherson LJ, Xiao B, Kwan KY, Petrus MJ, Dubin AE, Hwang S, Cravatt B, Corey DP, Patapoutian A (2007b) An ion channel essential for sensing chemical damage. J Neurosci 27:11412-11415
-
(2007)
J Neurosci
, vol.27
, pp. 11412-11415
-
-
MacPherson, L.J.1
Xiao, B.2
Kwan, K.Y.3
Petrus, M.J.4
Dubin, A.E.5
Hwang, S.6
Cravatt, B.7
Corey, D.P.8
Patapoutian, A.9
-
68
-
-
0037034931
-
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
-
McKemy DD, Neuhausser WM, Julius D (2002) Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature 416:52-58
-
(2002)
Nature
, vol.416
, pp. 52-58
-
-
McKemy, D.D.1
Neuhausser, W.M.2
Julius, D.3
-
69
-
-
33646043767
-
Increasingly irritable and close to tears: TRPA1 in inflammatory pain
-
McMahon SB, Wood JN (2006) Increasingly irritable and close to tears: TRPA1 in inflammatory pain. Cell 124:1123-1125
-
(2006)
Cell
, vol.124
, pp. 1123-1125
-
-
McMahon, S.B.1
Wood, J.N.2
-
71
-
-
0034724402
-
Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human
-
Mezey E, Toth ZE, Cortright DN, Arzubi MK, Krause JE, Elde R, Guo A, Blumberg PM, Szallasi A (2000) Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human. Proc Natl Acad Sci USA 97:3655-3660
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3655-3660
-
-
Mezey, E.1
Toth, Z.E.2
Cortright, D.N.3
Arzubi, M.K.4
Krause, J.E.5
Elde, R.6
Guo, A.7
Blumberg, P.M.8
Szallasi, A.9
-
72
-
-
0002215411
-
-
Churchill Livingstone, New York
-
Meyer RA, Campbell JN, Raja SN (1994) Peripheral neural mechanisms of nociception, 4th edn, Churchill Livingstone, New York
-
(1994)
Peripheral Neural Mechanisms of Nociception, 4th Edn
-
-
Meyer, R.A.1
Campbell, J.N.2
Raja, S.N.3
-
73
-
-
14644392188
-
Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin
-
Moqrich A, Hwang SW, Earley TJ, Petrus MJ, Murray AN, Spencer KS, Andahazy M, Story GM, Patapoutian A (2005) Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin. Science 307:1468-1472
-
(2005)
Science
, vol.307
, pp. 1468-1472
-
-
Moqrich, A.1
Hwang, S.W.2
Earley, T.J.3
Petrus, M.J.4
Murray, A.N.5
Spencer, K.S.6
Andahazy, M.7
Story, G.M.8
Patapoutian, A.9
-
74
-
-
0242266967
-
TRPV2 is a component of osmotically sensitive cation channels in murine aortic myocytes
-
Muraki K, Iwata Y, Katanosaka Y, Ito T, Ohya S, Shigekawa M, Imaizumi Y (2003) TRPV2 is a component of osmotically sensitive cation channels in murine aortic myocytes. Circ Res 93:829-838
-
(2003)
Circ Res
, vol.93
, pp. 829-838
-
-
Muraki, K.1
Iwata, Y.2
Katanosaka, Y.3
Ito, T.4
Ohya, S.5
Shigekawa, M.6
Imaizumi, Y.7
-
75
-
-
33846648488
-
Chemotactic peptide fMetLeuPhe induces translocation of the TRPV2 channel in macrophages
-
Nagasawa M, Nakagawa Y, Tanaka S, Kojima I (2007) Chemotactic peptide fMetLeuPhe induces translocation of the TRPV2 channel in macrophages. J Cell Physiol 210:692-702
-
(2007)
J Cell Physiol
, vol.210
, pp. 692-702
-
-
Nagasawa, M.1
Nakagawa, Y.2
Tanaka, S.3
Kojima, I.4
-
76
-
-
21344456496
-
TRPA1 and TRPM8 activation in humans: Effects of cinnamaldehyde and menthol
-
Namer B, Seifert F, Handwerker HO, Maihofner C (2005) TRPA1 and TRPM8 activation in humans: effects of cinnamaldehyde and menthol. Neuroreport 16:955-959
-
(2005)
Neuroreport
, vol.16
, pp. 955-959
-
-
Namer, B.1
Seifert, F.2
Handwerker, H.O.3
Maihofner, C.4
-
77
-
-
34447134440
-
Activation properties of heterologously expressed mammalian TRPV2: Evidence for species dependence
-
Neeper MP, Liu Y, Hutchinson TL, Wang Y, Flores CM, Qin N (2007) Activation properties of heterologously expressed mammalian TRPV2: evidence for species dependence. J Biol Chem 282:15894-15902
-
(2007)
J Biol Chem
, vol.282
, pp. 15894-15902
-
-
Neeper, M.P.1
Liu, Y.2
Hutchinson, T.L.3
Wang, Y.4
Flores, C.M.5
Qin, N.6
-
78
-
-
18344386202
-
A TRP channel that senses cold stimuli and menthol
-
Peier AM, Moqrich A et al (2002a) A TRP channel that senses cold stimuli and menthol. Cell 108:705-715
-
(2002)
Cell
, vol.108
, pp. 705-715
-
-
Peier, A.M.1
Moqrich, A.2
-
79
-
-
0037077041
-
A heat-sensitive TRP channel expressed in keratinocytes
-
Peier AM, Reeve AJ et al (2002b) A heat-sensitive TRP channel expressed in keratinocytes. Science 296:2046-2049
-
(2002)
Science
, vol.296
, pp. 2046-2049
-
-
Peier, A.M.1
Reeve, A.J.2
-
80
-
-
38949175353
-
A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition
-
Petrus M, Peier AM, Bandell M, Hwang SW, Huynh T, Olney N, Jegla T, Patapoutian A (2007) A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition. Mol Pain 3:40
-
(2007)
Mol Pain
, vol.3
, pp. 40
-
-
Petrus, M.1
Peier, A.M.2
Bandell, M.3
Hwang, S.W.4
Huynh, T.5
Olney, N.6
Jegla, T.7
Patapoutian, A.8
-
81
-
-
38949175353
-
A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition
-
Patapoutian A (2007) A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition. Mol Pain 3, 40
-
(2007)
Mol Pain
, vol.3
, pp. 40
-
-
Patapoutian, A.1
-
82
-
-
0034700494
-
Induction of vanilloid receptor channel activity by protein kinase C
-
Premkumar LS, Ahern GP (2000) Induction of vanilloid receptor channel activity by protein kinase C. Nature 408:985-990
-
(2000)
Nature
, vol.408
, pp. 985-990
-
-
Premkumar, L.S.1
Ahern, G.P.2
-
83
-
-
0037799198
-
A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity
-
Prescott ED, Julius D (2003) A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity. Science 300:1284-1288
-
(2003)
Science
, vol.300
, pp. 1284-1288
-
-
Prescott, E.D.1
Julius, D.2
-
84
-
-
33747179334
-
Analgesia mediated by the TRPM8 cold receptor in chronic neuropathic pain
-
Proudfoot CJ, Garry EM, Cottrell DF, Rosie R, Anderson H, Robertson DC, Fleetwood-Walker SM, Mitchell R (2006) Analgesia mediated by the TRPM8 cold receptor in chronic neuropathic pain. Curr Biol 16:1591-1605
-
(2006)
Curr Biol
, vol.16
, pp. 1591-1605
-
-
Proudfoot, C.J.1
Garry, E.M.2
Cottrell, D.F.3
Rosie, R.4
Anderson, H.5
Robertson, D.C.6
Fleetwood-Walker, S.M.7
Mitchell, R.8
-
85
-
-
0002840342
-
Peripheral neural mechanisms of nociception
-
Wall PD, Melzack R (eds) Churchill Livingston, Edinburgh
-
Raja SN, Meyer RA et al (1999) Peripheral neural mechanisms of nociception. In: Wall PD, Melzack R (eds) Textbook of pain. Churchill Livingston, Edinburgh
-
(1999)
Textbook of Pain
-
-
Raja, S.N.1
Meyer, R.A.2
-
86
-
-
0037373066
-
Novel expression of vanilloid receptor 1 on capsaicin-insensitive fibers accounts for the analgesic effect of capsaicin cream in neuropathic pain
-
Rashid MH, Inoue M, Kondo S, Kawashima T, Bakoshi S, Ueda H (2003) Novel expression of vanilloid receptor 1 on capsaicin-insensitive fibers accounts for the analgesic effect of capsaicin cream in neuropathic pain. J Pharmacol Exp Ther 304:940-948
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 940-948
-
-
Rashid, M.H.1
Inoue, M.2
Kondo, S.3
Kawashima, T.4
Bakoshi, S.5
Ueda, H.6
-
87
-
-
33845382786
-
TRPV1+ sensory neurons control beta cell stress and islet inflammation in autoimmune diabetes
-
Razavi R, Chan Y et al (2006) TRPV1+ sensory neurons control beta cell stress and islet inflammation in autoimmune diabetes. Cell 127:1123-1135
-
(2006)
Cell
, vol.127
, pp. 1123-1135
-
-
Razavi, R.1
Chan, Y.2
-
88
-
-
0022524574
-
Does neurogenic inflammation alter the sensitivity of unmyelinated nociceptors in the rat?
-
Reeh PW, Kocher L, Jung S (1986) Does neurogenic inflammation alter the sensitivity of unmyelinated nociceptors in the rat? Brain Res 384:42-50
-
(1986)
Brain Res
, vol.384
, pp. 42-50
-
-
Reeh, P.W.1
Kocher, L.2
Jung, S.3
-
89
-
-
17844373771
-
PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain
-
Rohacs T, Lopes CM, Michailidis I, Logothetis DE (2005) PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain. Nat Neurosci 8:626-634
-
(2005)
Nat Neurosci
, vol.8
, pp. 626-634
-
-
Rohacs, T.1
Lopes, C.M.2
Michailidis, I.3
Logothetis, D.E.4
-
90
-
-
0035940785
-
The distribution and regulation of vanilloid receptor VR1 and VR1 50 splice variant RNA expression in rat
-
Sanchez JF, Krause JE, Cortright DN (2001) The distribution and regulation of vanilloid receptor VR1 and VR1 50 splice variant RNA expression in rat. Neuroscience 107:373-381
-
(2001)
Neuroscience
, vol.107
, pp. 373-381
-
-
Sanchez, J.F.1
Krause, J.E.2
Cortright, D.N.3
-
91
-
-
0033787359
-
Sensory fibers of the pelvic nerve innervating the Rat's urinary bladder
-
Shea VK, Cai R, Crepps B, Mason JL, Perl ER (2000) Sensory fibers of the pelvic nerve innervating the Rat's urinary bladder. J Neurophysiol 84:1924-1933
-
(2000)
J Neurophysiol
, vol.84
, pp. 1924-1933
-
-
Shea, V.K.1
Cai, R.2
Crepps, B.3
Mason, J.L.4
Perl, E.R.5
-
92
-
-
28644439935
-
Peripheral inflammation induces up-regulation of TRPV2 expression in rat DRG
-
Shimosato G, Amaya F, Ueda M, Tanaka Y, Decosterd I, Tanaka M (2005) Peripheral inflammation induces up-regulation of TRPV2 expression in rat DRG. Pain 119:225-232
-
(2005)
Pain
, vol.119
, pp. 225-232
-
-
Shimosato, G.1
Amaya, F.2
Ueda, M.3
Tanaka, Y.4
Decosterd, I.5
Tanaka, M.6
-
93
-
-
18444408683
-
TRPV3 is a temperature-sensitive vanilloid receptor-like protein
-
Smith GD, Gunthorpe MJ et al (2002) TRPV3 is a temperature-sensitive vanilloid receptor-like protein. Nature 418:186-190
-
(2002)
Nature
, vol.418
, pp. 186-190
-
-
Smith, G.D.1
Gunthorpe, M.J.2
-
94
-
-
33749562292
-
Bisandrographolide from andrographis paniculata activates TRPV4 channels
-
Smith PL, Maloney KN, Pothen RG, Clardy J, Clapham DE (2006) Bisandrographolide from Andrographis paniculata activates TRPV4 channels. J Biol Chem 281:29897-29904
-
(2006)
J Biol Chem
, vol.281
, pp. 29897-29904
-
-
Smith, P.L.1
Maloney, K.N.2
Pothen, R.G.3
Clardy, J.4
Clapham, D.E.5
-
95
-
-
34447504896
-
Nonthermal activation of transient receptor potential vanilloid- 1 channels in abdominal viscera tonically inhibits autonomic cold-defense effectors
-
Steiner AA, Turek VF et al (2007) Nonthermal activation of transient receptor potential vanilloid- 1 channels in abdominal viscera tonically inhibits autonomic cold-defense effectors. J Neurosci 27:7459-7468
-
(2007)
J Neurosci
, vol.27
, pp. 7459-7468
-
-
Steiner, A.A.1
Turek, V.F.2
-
96
-
-
0345616438
-
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures
-
Story GM, Peier AM et al (2003) ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell 112:819-829
-
(2003)
Cell
, vol.112
, pp. 819-829
-
-
Story, G.M.1
Peier, A.M.2
-
97
-
-
0033178342
-
Isolectin B(4)-positive and -negative nociceptors are functionally distinct
-
Stucky CL, Lewin GR (1999) Isolectin B(4)-positive and -negative nociceptors are functionally distinct. J Neurosci 19:6497-6505
-
(1999)
J Neurosci
, vol.19
, pp. 6497-6505
-
-
Stucky, C.L.1
Lewin, G.R.2
-
98
-
-
0038604287
-
Impaired pressure sensation in mice lacking TRPV4
-
DOI 10.1074/jbc.M302561200
-
Suzuki M, Mizuno A, Kodaira K, Imai M (2003) Impaired pressure sensation in mice lacking TRPV4. J Biol Chem 278:22664-22668 (Pubitemid 36830325)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.25
, pp. 22664-22668
-
-
Suzuki, M.1
Mizuno, A.2
Kodaira, K.3
Imai, M.4
-
99
-
-
20144376596
-
Identification and biological evaluation of 4-(3-trifluoromethylpyridin- 2-yl)piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl)amide, a high affinity TRPV1 (VR1) vanilloid receptor antagonist
-
Swanson DM, Dubin AE et al (2005) Identification and biological evaluation of 4-(3-trifluoromethylpyridin- 2-yl)piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl)amide, a high affinity TRPV1 (VR1) vanilloid receptor antagonist. J Med Chem 48:1857-1872
-
(2005)
J Med Chem
, vol.48
, pp. 1857-1872
-
-
Swanson, D.M.1
Dubin, A.E.2
-
100
-
-
0032970173
-
Vanilloid (Capsaicin) receptors and mechanisms
-
Szallasi A, Blumberg PM (1999) Vanilloid (Capsaicin) receptors and mechanisms. Pharmacol Rev 51:159-212
-
(1999)
Pharmacol Rev
, vol.51
, pp. 159-212
-
-
Szallasi, A.1
Blumberg, P.M.2
-
101
-
-
34248138496
-
The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept
-
Szallasi A, Cortright DN, Blum CA, Eid SR (2007) The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept. Nat Rev Drug Discov 6:357-372
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 357-372
-
-
Szallasi, A.1
Cortright, D.N.2
Blum, C.A.3
Eid, S.R.4
-
102
-
-
42949108141
-
Design and Synthesis of Peripherally Restricted Transient Receptor Potential Vanilloid 1 (TRPV1) Antagonists
-
Tamayo N, Liao H et al (2008) Design and Synthesis of Peripherally Restricted Transient Receptor Potential Vanilloid 1 (TRPV1) Antagonists. J Med Chem 51:2744-2757
-
(2008)
J Med Chem
, vol.51
, pp. 2744-2757
-
-
Tamayo, N.1
Liao, H.2
-
103
-
-
38549092780
-
Prostaglandin-induced activation of nociceptive neurons via direct interaction with transient receptor potential A1 (TRPA1)
-
Taylor-Clark TE, Undem BJ, Macglashan DW Jr, Ghatta S, Carr MJ, McAlexander MA (2008) Prostaglandin-induced activation of nociceptive neurons via direct interaction with transient receptor potential A1 (TRPA1). Mol Pharmacol 73:274-281
-
(2008)
Mol Pharmacol
, vol.73
, pp. 274-281
-
-
Taylor-Clark, T.E.1
Undem, B.J.2
Jr M.Dw3
Ghatta, S.4
Carr, M.J.5
McAlexander, M.A.6
-
104
-
-
4143079214
-
Warm temperature-sensitive transient receptor potential vanilloid 4 (TRPV4) plays an essential role in thermal hyperalgesia
-
Todaka H, Taniguchi J, Satoh J, Mizuno A, Suzuki M (2004) Warm temperature-sensitive transient receptor potential vanilloid 4 (TRPV4) plays an essential role in thermal hyperalgesia. J Biol Chem 279:35133-35138
-
(2004)
J Biol Chem
, vol.279
, pp. 35133-35138
-
-
Todaka, H.1
Taniguchi, J.2
Satoh, J.3
Mizuno, A.4
Suzuki, M.5
-
105
-
-
33846918649
-
Nociception and TRP channels
-
Tominaga M (2007) Nociception and TRP channels. Handb Exp Pharmacol, 489-505
-
(2007)
Handb Exp Pharmacol
, pp. 489-505
-
-
Tominaga, M.1
-
106
-
-
0032169804
-
The cloned capsaicin receptor integrates multiple pain-producing stimuli
-
Tominaga M, Caterina MJ, Malmberg AB, Rosen TA, Gilbert H, Skinner K, Raumann BE, Basbaum AI, Julius D (1998) The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron 21:531-543
-
(1998)
Neuron
, vol.21
, pp. 531-543
-
-
Tominaga, M.1
Caterina, M.J.2
Malmberg, A.B.3
Rosen, T.A.4
Gilbert, H.5
Skinner, K.6
Raumann, B.E.7
Basbaum, A.I.8
Julius, D.9
-
107
-
-
34548094044
-
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
-
Trevisani M, Siemens J et al (2007) 4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1. Proc Natl Acad Sci USA 104:13519-13524
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 13519-13524
-
-
Trevisani, M.1
Siemens, J.2
-
108
-
-
34250160572
-
Monoterpenoid agonists of TRPV3
-
Vogt-Eisele AK, Weber K, Sherkheli MA, Vielhaber G, Panten J, Gisselmann G, Hatt H (2007) Monoterpenoid agonists of TRPV3. Br J Pharmacol 151:530-540
-
(2007)
Br J Pharmacol
, vol.151
, pp. 530-540
-
-
Vogt-Eisele, A.K.1
Weber, K.2
Sherkheli, M.A.3
Vielhaber, G.4
Panten, J.5
Gisselmann, G.6
Hatt, H.7
-
109
-
-
33644987046
-
A novel mechanism contributing to development of Dahl salt-sensitive hypertension: Role of the transient receptor potential vanilloid type 1
-
Wang Y, Wang DH (2006) A novel mechanism contributing to development of Dahl salt-sensitive hypertension: role of the transient receptor potential vanilloid type 1. Hypertension 47:609-614
-
(2006)
Hypertension
, vol.47
, pp. 609-614
-
-
Wang, Y.1
Wang, D.H.2
-
110
-
-
0030070938
-
A comparison of the effects of noxious and innocuous counterstimuli on experimentally induced itch and pain
-
Ward L, Wright E, McMahon SB (1996) A comparison of the effects of noxious and innocuous counterstimuli on experimentally induced itch and pain. Pain 64:129-138
-
(1996)
Pain
, vol.64
, pp. 129-138
-
-
Ward, L.1
Wright, E.2
McMahon, S.B.3
-
111
-
-
23044500197
-
Conservation of functional and pharmacological properties in the distantly related temperature sensors TRVP1 and TRPM8
-
Weil A, Moore SE, Waite NJ, Randall A, Gunthorpe MJ (2005) Conservation of functional and pharmacological properties in the distantly related temperature sensors TRVP1 and TRPM8. Mol Pharmacol 68:518-527
-
(2005)
Mol Pharmacol
, vol.68
, pp. 518-527
-
-
Weil, A.1
Moore, S.E.2
Waite, N.J.3
Randall, A.4
Gunthorpe, M.J.5
-
112
-
-
44449102835
-
Calcium plays a central role in the sensitization of TRPV3 channel to repetitive stimulations
-
Xiao R, Tang J, Wang C, Colton CK, Tian J, Zhu MX (2008) Calcium plays a central role in the sensitization of TRPV3 channel to repetitive stimulations. J Biol Chem 283:6162-6174
-
(2008)
J Biol Chem
, vol.283
, pp. 6162-6174
-
-
Xiao, R.1
Tang, J.2
Wang, C.3
Colton, C.K.4
Tian, J.5
Zhu, M.X.6
-
113
-
-
37249065119
-
TRPM8 mechanism of cold allodynia after chronic nerve injury
-
Xing H, Chen M, Ling J, Tan W, Gu JG (2007) TRPM8 mechanism of cold allodynia after chronic nerve injury. J Neurosci 27:13680-13690
-
(2007)
J Neurosci
, vol.27
, pp. 13680-13690
-
-
Xing, H.1
Chen, M.2
Ling, J.3
Tan, W.4
Gu, J.G.5
-
114
-
-
0037062915
-
TRPV3 is a calcium-permeable temperature-sensitive cation channel
-
Xu H, Ramsey IS et al (2002) TRPV3 is a calcium-permeable temperature-sensitive cation channel. Nature 418:181-186
-
(2002)
Nature
, vol.418
, pp. 181-186
-
-
Xu, H.1
Ramsey, I.S.2
-
115
-
-
0038175469
-
Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress
-
Xu H, Zhao H, Tian W, Yoshida K, Roullet JB, Cohen DM (2003) Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress. J Biol Chem 278:11520-11527
-
(2003)
J Biol Chem
, vol.278
, pp. 11520-11527
-
-
Xu, H.1
Zhao, H.2
Tian, W.3
Yoshida, K.4
Roullet, J.B.5
Cohen, D.M.6
-
116
-
-
25644433563
-
Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism
-
Xu H, Blair NT, Clapham DE (2005) Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism. J Neurosci 25:8924-8937
-
(2005)
J Neurosci
, vol.25
, pp. 8924-8937
-
-
Xu, H.1
Blair, N.T.2
Clapham, D.E.3
-
117
-
-
33745742247
-
Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels
-
Xu H, Delling M, Jun JC, Clapham DE (2006) Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels. Nat Neurosci 9:628-635
-
(2006)
Nat Neurosci
, vol.9
, pp. 628-635
-
-
Xu, H.1
Delling, M.2
Jun, J.C.3
Clapham, D.E.4
-
118
-
-
33847241778
-
Direct activation of the ion channel TRPA1 by Ca2+
-
Zurborg S, Yurgionas B, Jira JA, Caspani O, Heppenstall PA (2007) Direct activation of the ion channel TRPA1 by Ca2+. Nat Neurosci 10:277-279
-
(2007)
Nat Neurosci
, vol.10
, pp. 277-279
-
-
Zurborg, S.1
Yurgionas, B.2
Jira, J.A.3
Caspani, O.4
Heppenstall, P.A.5
|