Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay

British Journal of Pharmacology

Volumn 141, Issue 4, 2004, Pages 737-745

  Behrendt, H J ^a,b   Germann, T ^a   Gillen, C ^a   Hatt, H ^b   Jostock, R ^a  

^a GRÜNENTHAL GMBH   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

CMR1; Cold; FLIPR; Menthol; Odorants; Pain; Proton activation; TRPM8; VR1

Indexed keywords

1 (2 HYDROXYPHENYL) 4 (3 NITROPHENYL) 1,2,3,6 TETRAHYDROPYRIMIDIN 2 ONE; AMIDE; CALCIUM CHANNEL; CALCIUM ION; CAPSAZEPINE; CINEOLE; COLD MENTHOL RECEPTOR; COOLACTP; COOLING AGENT 10; FRESCOLATMGA; FRESCOLATML; GERANIOL; HYDROXYCITRONELLAL; LINALOOL; MEMBRANE RECEPTOR; MENTHOL; N (4 TERT BUTYLPHENYL) 4 (3 CHLOROPYRIDIN 2 YL)TETRAHYDROPYRAZINE 1(2H) CARBOXAMIDE; N (4 TERT BUTYLPHENYL) 4 (3 CHLOROPYRIDIN 2 YL)TETRAHYDROPYRAZINE 1(2H) THIOCARBOXAMIDE; N ARACHIDONOYLDOPAMINE; PMD38; PROTEIN TRPM8; RECOMBINANT PROTEIN; RECOMBINANT PROTEIN TRPM8; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 1 AGONIST; VANILLOID RECEPTOR 1 ANTAGONIST; WS 23; WS 3;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG POTENTIATION; FLUOROMETRIC IMAGING PLATE READER ASSAY; FLUOROMETRY; HUMAN; HUMAN CELL; IC 50; INHIBITION KINETICS; LOW TEMPERATURE PROCEDURES; MEMBRANE PERMEABILITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTON TRANSPORT; RECEPTOR POTENTIAL;

ANIMALS; CALCIUM SIGNALING; CELL LINE; CLONING, MOLECULAR; DIAGNOSTIC IMAGING; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUOROMETRY; HYDROGEN-ION CONCENTRATION; ION CHANNELS; LIGANDS; MICE; NEOPLASM PROTEINS; ODORS; RECEPTORS, DRUG; TRANSFECTION; TRPM CATION CHANNELS;

EID: 1842453817     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705652     Document Type: Article

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