Activation of protein kinase C sensitizes human VR1 to capsaicin and to moderate decreases in pH at physiological temperatures in Xenopus oocytes

Pain

Volumn 98, Issue 1-2, 2002, Pages 109-117

  Crandall, Marci ^a   Kwash, Jennifer ^a   Yu, Weifeng ^a   White, Geoffrey ^a  

^a NEUROGEN CORPORATION   (United States)

Author keywords

Capsaicin; Hyperalgesia; Protein kinase C; Vanilloid receptor 1

Indexed keywords

CAPSAICIN; PHORBOL DIBUTYRATE; PROTEIN KINASE C; RNA; STAUROSPORINE; VANILLOID RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; ELECTRODE; ENZYME ACTIVATION; EVOKED RESPONSE; INTRACELLULAR RECORDING; ION CURRENT; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PH; PRIORITY JOURNAL; RECEPTOR SENSITIVITY; ROOM TEMPERATURE; SENSITIZATION; SKIN TEMPERATURE; VOLTAGE CLAMP; XENOPUS LAEVIS;

ANIMALS; CAPSAICIN; ELECTROPHYSIOLOGY; ENZYME ACTIVATION; FEMALE; HUMANS; HYDROGEN; HYDROGEN-ION CONCENTRATION; OOCYTES; PROTEIN KINASE C; RECEPTORS, DRUG; TEMPERATURE; XENOPUS LAEVIS;

EID: 0036291431     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(02)00034-9     Document Type: Article

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