Engineering the substrate binding site of benzoylformate decarboxylase

Biochemistry

Volumn 48, Issue 35, 2009, Pages 8387-8395

  Yep, Alejandra ^a   McLeish, Michael J ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC ACTIVITY; DECARBOXYLASES; DIFFERENT SUBSTRATES; DOUBLE MUTANTS; INHIBITOR MOLECULES; KETO ACIDS; PYRUVATE DECARBOXYLASE; PYRUVATES; SATURATION MUTAGENESIS; SEMI-RANDOM; SUBSTRATE UTILIZATION; SUBSTRATE-BINDING SITES; THIAMIN DIPHOSPHATE-DEPENDENT ENZYMES; THREE-DIMENSIONAL STRUCTURE; WILD-TYPE ENZYMES; ZYMOMONAS MOBILIS;

BINDING ENERGY; BINDING SITES; CARBOXYLATION; ENZYMES; MUTAGENESIS;

SUBSTRATES;

BENZOYLFORMATE DECARBOXYLASE; CARBOXYLYASE; PYRUVATE DECARBOXYLASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CATALYSIS; CONTROLLED STUDY; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SUBSTITUTION; BINDING SITES; CARBOXY-LYASES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; MODELS, CHEMICAL; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN ENGINEERING; PYRUVATE DECARBOXYLASE; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

ZYMOMONAS MOBILIS;

EID: 69749101294     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9008402     Document Type: Article

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