Structural and kinetic analysis of catalysis by a thiamin diphosphate-dependent enzyme, benzoylformate decarboxylase

Biochemistry

Volumn 42, Issue 7, 2003, Pages 1820-1830

  Polovnikova, Elena S ^a,d   McLeish, Michael J ^b   Sergienko, Eduard A ^c   Burgner, John T ^a   Anderson, Natalie L ^a   Bera, Asim K ^a   Jordan, Frank ^c   Kenyon, George L ^b   Hasson, Miriam S ^a  

^a PURDUE UNIVERSITY   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c RUTGERS UNIVERSITY   (United States)

^d Kilpatrick Stockton LLP   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; ENZYME INHIBITION; HYDROGEN BONDS; MOLECULAR STRUCTURE; REACTION KINETICS; SUBSTRATES;

PROTONATION;

ENZYMES;

4 NITROBENZOIC ACID; BENZOYLFORMATE DECARBOXYLASE; CARBOXYLASE; ENAMINE; ENZYME INHIBITOR; MANDELIC ACID; PHENYLGLYOXYLIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; DECARBOXYLATION; ENZYME BINDING; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; KINETICS; PRIORITY JOURNAL; PROTON TRANSPORT; STEADY STATE; STRUCTURE ANALYSIS;

ALANINE; BINDING SITES; BINDING, COMPETITIVE; CARBOXY-LYASES; CATALYSIS; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; HISTIDINE; KINETICS; LIGANDS; MANDELIC ACIDS; MUTAGENESIS, SITE-DIRECTED; PSEUDOMONAS PUTIDA; SERINE; SPECTROPHOTOMETRY; THIAMINE PYROPHOSPHATE;

EID: 0344754095     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi026490k     Document Type: Article

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