Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates

Genes and Development

Volumn 18, Issue 6, 2004, Pages 641-659

  Chen, Miao Hsueh ^a   Li, Ya Jun ^a   Kawakami, Takatoshi ^a   Xu, Shan Mei ^a   Chuang, Pao Tien ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cholesterol; Hedgehog; Lipid modification; Multimerization; Palmitoylation; Signaling

Indexed keywords

SONIC HEDGEHOG PROTEIN;

ARTICLE; BIOCHEMISTRY; CATALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; DROSOPHILA SKI GENE; EMBRYO DEVELOPMENT; GENE TARGETING; GENETIC ANALYSIS; KNOCKOUT GENE; KNOCKOUT MOUSE; LIPID METABOLISM; LIPID SOLUBILITY; MEMBRANE BINDING; MOLECULAR MECHANICS; MORPHOGENESIS; NONHUMAN; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; SIGNAL PROCESSING; VERTEBRATE;

ANIMALS; HEDGEHOG PROTEINS; MEMBRANE MICRODOMAINS; MICE; MICE, TRANSGENIC; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

ERINACEIDAE; MURINAE; VERTEBRATA;

EID: 1842853184     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1185804     Document Type: Article

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