Dihydroxyacetone phosphate aldolase catalyzed synthesis of structurally diverse polyhydroxylated pyrrolidine derivatives and evaluation of their glycosidase inhibitory properties

Chemistry - A European Journal

Volumn 15, Issue 30, 2009, Pages 7310-7328

  Calveras, Jordi ^a   Egido Gabás, Meritxell ^a   Gómez, Livia ^a   Casas, Josefina ^a   Parella, Teodor ^b   Joglar, Jesús ^a   Bujons, Jordi ^a   Clapés, Pere ^a  

^a INSTITUTE OF ADVANCED CHEMISTRY OF CATALONIA IQAC CSIC   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Aldol reaction; Amino aldehydes; Cyclitols; Enzyme catalysis; Glycosidase inhibitors

Indexed keywords

ALDOL REACTION; AMINO ALDEHYDES; CYCLITOLS; ENZYME CATALYSIS; GLYCOSIDASE INHIBITORS;

ALCOHOLS; ALDEHYDES; AMINATION; AMINES; CATALYSIS; ENZYMES; ESCHERICHIA COLI; HYDROXYLATION; STEREOSELECTIVITY;

ALKYLATION;

ALDEHYDE; DIHYDROXYACETONE PHOSPHATE; GLYCOSIDASE; L FUCULOSEPHOSPHATE ALDOLASE; L-FUCULOSEPHOSPHATE ALDOLASE; LYASE; PYRROLIDINE DERIVATIVE; RHAMNULOSE 1 PHOSPHATE ADOLASE; RHAMNULOSE-1-PHOSPHATE ADOLASE;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; ESCHERICHIA COLI; METABOLISM; STEREOISOMERISM; SYNTHESIS;

ALDEHYDE-LYASES; ALDEHYDES; CATALYSIS; DIHYDROXYACETONE PHOSPHATE; ESCHERICHIA COLI; GLYCOSIDE HYDROLASES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PYRROLIDINES; STEREOISOMERISM;

EID: 67651067950     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.200900838     Document Type: Article

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