Combinatorial library of five-membered iminocyclitol and the inhibitory activities against glyco-enzymes

Chemistry and Biology

Volumn 8, Issue 11, 2001, Pages 1061-1070

  Saotome, Chikako ^a   Wong, Chi Huey ^b   Kanie, Osamu ^a  

^a MITSUBISHI KAGAKU INSTITUTE OF LIFE SCIENCES   (Japan)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Combinatorial library; Glycosidase; Glycosyltransferase; Iminocyclitol; Inhibitor

Indexed keywords

1 DEOXYMANNONOJIRIMYCIN; ALDEHYDE; ALKYL GROUP; ALPHA MANNOSIDASE; COMBINATORIAL LIBRARY; CONCENTRATION (PARAMETERS); ENZYME INHIBITION; ENZYME INHIBITOR; GLYCOSIDASE; GLYCOSYLTRANSFERASE; IMINOCYCLITOL; OLIGOSACCHARIDE; REACTION MECHANISM; SPECIFICITY;

AMINO SUGARS; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; GLYCOSIDE HYDROLASES; HEXOSYLTRANSFERASES; IMINES; MOLECULAR MIMICRY; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; SUGAR ALCOHOLS;

EID: 0035194309     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(01)00074-6     Document Type: Article

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