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Volumn 118, Issue 4, 2009, Pages 405-418

An elegant miRror: microRNAs in stem cells, developmental timing and cancer

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; OCTAMER TRANSCRIPTION FACTOR 4; ONCOPROTEIN; PROTEIN LET 7; PROTEIN LIN 28; PROTEIN LIN 29; PROTEIN LIN 4; PROTEIN LIN 41; RNA POLYMERASE II; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DAF 12; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; TRIPARTITE MOTIF PROTEIN 5; UNCLASSIFIED DRUG;

EID: 67649556287     PISSN: 00095915     EISSN: 14320886     Source Type: Journal    
DOI: 10.1007/s00412-009-0210-z     Document Type: Review
Times cited : (117)

References (115)
  • 1
    • 24144494563 scopus 로고    scopus 로고
    • The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans
    • Abbott AL, Alvarez-Saavedra E, Miska EA, Lau NC, Bartel DP, Horvitz HR, Ambros V (2005) The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Dev Cell 9:403-414
    • (2005) Dev Cell , vol.9 , pp. 403-414
    • Abbott, A.L.1    Alvarez-Saavedra, E.2    Miska, E.A.3    Lau, N.C.4    Bartel, D.P.5    Horvitz, H.R.6    Ambros, V.7
  • 2
    • 0038708326 scopus 로고    scopus 로고
    • The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs
    • Abrahante JE, Daul AL, Li M, Volk ML, Tennessen JM, Miller EA, Rougvie AE (2003) The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs. Dev Cell 4:625-637
    • (2003) Dev Cell , vol.4 , pp. 625-637
    • Abrahante, J.E.1    Daul, A.L.2    Li, M.3    Volk, M.L.4    Tennessen, J.M.5    Miller, E.A.6    Rougvie, A.E.7
  • 3
    • 0035966319 scopus 로고    scopus 로고
    • microRNAs: Tiny regulators with great potential
    • Ambros V (2001) microRNAs: Tiny regulators with great potential. Cell 107:823-826
    • (2001) Cell , vol.107 , pp. 823-826
    • Ambros, V.1
  • 4
    • 0021771445 scopus 로고
    • Heterochronic mutants of the nematode Caenorhabditis elegans
    • (New York, NY)
    • Ambros V, Horvitz HR (1984) Heterochronic mutants of the nematode Caenorhabditis elegans. Science (New York, NY) 226:409-416
    • (1984) Science , vol.226 , pp. 409-416
    • Ambros, V.1    Horvitz, H.R.2
  • 6
    • 34447530917 scopus 로고    scopus 로고
    • Localization of the developmental timing regulator Lin28 to mRNP complexes, P-bodies and stress granules
    • Balzer E, Moss EG (2007) Localization of the developmental timing regulator Lin28 to mRNP complexes, P-bodies and stress granules. RNA Biol 4:16-25
    • (2007) RNA Biol , vol.4 , pp. 16-25
    • Balzer, E.1    Moss, E.G.2
  • 7
    • 42649112047 scopus 로고    scopus 로고
    • An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
    • Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, Regev A, Weinberg RA (2008) An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Gen 40:499-507
    • (2008) Nat Gen , vol.40 , pp. 499-507
    • Ben-Porath, I.1    Thomson, M.W.2    Carey, V.J.3    Ge, R.4    Bell, G.W.5    Regev, A.6    Weinberg, R.A.7
  • 8
    • 33646027006 scopus 로고    scopus 로고
    • Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells
    • Betschinger J, Mechtler K, Knoblich JA (2006) Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells. Cell 124:1241-1253
    • (2006) Cell , vol.124 , pp. 1241-1253
    • Betschinger, J.1    Mechtler, K.2    Knoblich, J.A.3
  • 9
    • 33947273235 scopus 로고    scopus 로고
    • Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila
    • Brennecke J, Aravin AA, Stark A, Dus M, Kellis M, Sachidanandam R, Hannon GJ (2007) Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell 128:1089-1103
    • (2007) Cell , vol.128 , pp. 1089-1103
    • Brennecke, J.1    Aravin, A.A.2    Stark, A.3    Dus, M.4    Kellis, M.5    Sachidanandam, R.6    Hannon, G.J.7
  • 11
    • 45849084987 scopus 로고    scopus 로고
    • Temporal regulation of metamorphic processes in Drosophila by the let-7 and miR-125 heterochronic microRNAs
    • Caygill EE, Johnston LA (2008) Temporal regulation of metamorphic processes in Drosophila by the let-7 and miR-125 heterochronic microRNAs. Curr Biol 18:943-950
    • (2008) Curr Biol , vol.18 , pp. 943-950
    • Caygill, E.E.1    Johnston, L.A.2
  • 13
    • 54249117763 scopus 로고    scopus 로고
    • A SNP in a let-7 microRNA complementary site in the KRAS 3′ untranslated region increases non-small cell lung cancer risk
    • Chin LJ, Ratner E, Leng S, Zhai R, Nallur S, Babar I, Muller RU, Straka E, Su L, Burki EA et al (2008) A SNP in a let-7 microRNA complementary site in the KRAS 3′ untranslated region increases non-small cell lung cancer risk. Cancer Res 68:8535-8540
    • (2008) Cancer Res , vol.68 , pp. 8535-8540
    • Chin, L.J.1    Ratner, E.2    Leng, S.3    Zhai, R.4    Nallur, S.5    Babar, I.6    Muller, R.U.7    Straka, E.8    Su, L.9    Burki, E.A.10
  • 16
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs - Micrornas with a role in cancer
    • Esquela-Kerscher A, Slack FJ (2006) Oncomirs - microRNAs with a role in cancer. Nat Rev 6:259-269
    • (2006) Nat Rev , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 17
    • 28444441562 scopus 로고    scopus 로고
    • Post-embryonic expression of C. elegans microRNAs belonging to the lin-4 and let-7 families in the hypodermis and the reproductive system
    • Esquela-Kerscher A, Johnson SM, Bai L, Saito K, Partridge J, Reinert KL, Slack FJ (2005) Post-embryonic expression of C. elegans microRNAs belonging to the lin-4 and let-7 families in the hypodermis and the reproductive system. Dev Dyn 234:868-877
    • (2005) Dev Dyn , vol.234 , pp. 868-877
    • Esquela-Kerscher, A.1    Johnson, S.M.2    Bai, L.3    Saito, K.4    Partridge, J.5    Reinert, K.L.6    Slack, F.J.7
  • 20
    • 33745336617 scopus 로고    scopus 로고
    • A germline-specific class of small RNAs binds mammalian Piwi proteins
    • Girard A, Sachidanandam R, Hannon GJ, Carmell MA (2006) A germline-specific class of small RNAs binds mammalian Piwi proteins. Nature 442:199-202
    • (2006) Nature , vol.442 , pp. 199-202
    • Girard, A.1    Sachidanandam, R.2    Hannon, G.J.3    Carmell, M.A.4
  • 21
    • 17844364875 scopus 로고    scopus 로고
    • Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
    • Grishok A, Pasquinelli AE, Conte D, Li N, Parrish S, Ha I, Baillie DL, Fire A, Ruvkun G, Mello CC (2001) Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106:23-34
    • (2001) Cell , vol.106 , pp. 23-34
    • Grishok, A.1    Pasquinelli, A.E.2    Conte, D.3    Li, N.4    Parrish, S.5    Ha, I.6    Baillie, D.L.7    Fire, A.8    Ruvkun, G.9    Mello, C.C.10
  • 22
    • 33745621037 scopus 로고    scopus 로고
    • A novel class of small RNAs in mouse spermatogenic cells
    • Grivna ST, Beyret E, Wang Z, Lin H (2006) A novel class of small RNAs in mouse spermatogenic cells. Genes Dev 20:1709-1714
    • (2006) Genes Dev , vol.20 , pp. 1709-1714
    • Grivna, S.T.1    Beyret, E.2    Wang, Z.3    Lin, H.4
  • 23
    • 14644398601 scopus 로고    scopus 로고
    • The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans
    • Grosshans H, Johnson T, Reinert KL, Gerstein M, Slack FJ (2005) The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans. Dev Cell 8:321-330
    • (2005) Dev Cell , vol.8 , pp. 321-330
    • Grosshans, H.1    Johnson, T.2    Reinert, K.L.3    Gerstein, M.4    Slack, F.J.5
  • 24
    • 33751042873 scopus 로고    scopus 로고
    • Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma
    • Guo Y, Chen Y, Ito H, Watanabe A, Ge X, Kodama T, Aburatani H (2006) Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma. Gene 384:51-61
    • (2006) Gene , vol.384 , pp. 51-61
    • Guo, Y.1    Chen, Y.2    Ito, H.3    Watanabe, A.4    Ge, X.5    Kodama, T.6    Aburatani, H.7
  • 25
    • 0032480236 scopus 로고    scopus 로고
    • lin-14 regulates the timing of synaptic remodelling in Caenorhabditis elegans
    • Hallam SJ, Jin Y (1998) lin-14 regulates the timing of synaptic remodelling in Caenorhabditis elegans. Nature 395:78-82
    • (1998) Nature , vol.395 , pp. 78-82
    • Hallam, S.J.1    Jin, Y.2
  • 26
    • 61349169058 scopus 로고    scopus 로고
    • nhl-2 Modulates microRNA activity in Caenorhabditis elegans
    • Hammell CM, Lubin I, Boag PR, Blackwell TK, Ambros V (2009) nhl-2 Modulates microRNA activity in Caenorhabditis elegans. Cell 136:926-938
    • (2009) Cell , vol.136 , pp. 926-938
    • Hammell, C.M.1    Lubin, I.2    Boag, P.R.3    Blackwell, T.K.4    Ambros, V.5
  • 27
    • 34250636791 scopus 로고    scopus 로고
    • Misexpression of the Caenorhabditis elegans miRNA let-7 is sufficient to drive developmental programs
    • Hayes GD, Ruvkun G (2006) Misexpression of the Caenorhabditis elegans miRNA let-7 is sufficient to drive developmental programs. Cold Spring Harbor Symp Quant Biol 71:21-27
    • (2006) Cold Spring Harbor Symp Quant Biol , vol.71 , pp. 21-27
    • Hayes, G.D.1    Ruvkun, G.2
  • 28
    • 53949088050 scopus 로고    scopus 로고
    • Lin28 mediates the terminal uridylation of let-7 precursor microRNA
    • Heo I, Joo C, Cho J, Ha M, Han J, Kim VN (2008) Lin28 mediates the terminal uridylation of let-7 precursor microRNA. Mol Cell 32:276-284
    • (2008) Mol Cell , vol.32 , pp. 276-284
    • Heo, I.1    Joo, C.2    Cho, J.3    Ha, M.4    Han, J.5    Kim, V.N.6
  • 29
    • 37249031072 scopus 로고    scopus 로고
    • A role for microRNAs in maintenance of mouse mammary epithelial progenitor cells
    • Ibarra I, Erlich Y, Muthuswamy SK, Sachidanandam R, Hannon GJ (2007) A role for microRNAs in maintenance of mouse mammary epithelial progenitor cells. Genes Dev 21:3238-3243
    • (2007) Genes Dev , vol.21 , pp. 3238-3243
    • Ibarra, I.1    Erlich, Y.2    Muthuswamy, S.K.3    Sachidanandam, R.4    Hannon, G.J.5
  • 30
    • 0033527724 scopus 로고    scopus 로고
    • Similarity of the C. elegans developmental timing protein LIN-42 to circadian rhythm proteins
    • (New York, NY)
    • Jeon M, Gardner HF, Miller EA, Deshler J, Rougvie AE (1999) Similarity of the C. elegans developmental timing protein LIN-42 to circadian rhythm proteins. Science (New York, NY) 286:1141-1146
    • (1999) Science , vol.286 , pp. 1141-1146
    • Jeon, M.1    Gardner, H.F.2    Miller, E.A.3    Deshler, J.4    Rougvie, A.E.5
  • 31
    • 33947106486 scopus 로고    scopus 로고
    • Dcr-1 maintains Drosophila ovarian stem cells
    • Jin Z, Xie T (2007) Dcr-1 maintains Drosophila ovarian stem cells. Curr Biol 17:539-544
    • (2007) Curr Biol , vol.17 , pp. 539-544
    • Jin, Z.1    Xie, T.2
  • 32
    • 0037772254 scopus 로고    scopus 로고
    • The time of appearance of the C. elegans let-7 microRNA is transcriptionally controlled utilizing a temporal regulatory element in its promoter
    • Johnson SM, Lin SY, Slack FJ (2003) The time of appearance of the C. elegans let-7 microRNA is transcriptionally controlled utilizing a temporal regulatory element in its promoter. Dev Biol 259:364-379
    • (2003) Dev Biol , vol.259 , pp. 364-379
    • Johnson, S.M.1    Lin, S.Y.2    Slack, F.J.3
  • 35
    • 33645461834 scopus 로고    scopus 로고
    • Cloning and regulation of the vertebrate homologue of lin-41 that functions as a heterochronic gene in Caenorhabditis elegans
    • Kanamoto T, Terada K, Yoshikawa H, Furukawa T (2006) Cloning and regulation of the vertebrate homologue of lin-41 that functions as a heterochronic gene in Caenorhabditis elegans. Dev Dyn 235:1142-1149
    • (2006) Dev Dyn , vol.235 , pp. 1142-1149
    • Kanamoto, T.1    Terada, K.2    Yoshikawa, H.3    Furukawa, T.4
  • 42
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • (New York, NY)
    • Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T (2001) Identification of novel genes coding for small expressed RNAs. Science (New York, NY) 294:853-858
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 45
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • (New York, NY)
    • Lau NC, Lim LP, Weinstein EG, Bartel DP (2001) An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science (New York, NY) 294:858-862
    • (2001) Science , vol.294 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 47
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • (New York, NY)
    • Lee RC, Ambros V (2001) An extensive class of small RNAs in Caenorhabditis elegans. Science (New York, NY) 294:862-864
    • (2001) Science , vol.294 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 48
    • 34247565615 scopus 로고    scopus 로고
    • The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
    • Lee YS, Dutta A (2007) The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev 21:1025-1030
    • (2007) Genes Dev , vol.21 , pp. 1025-1030
    • Lee, Y.S.1    Dutta, A.2
  • 49
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee RC, Feinbaum RL, Ambros V (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75:843-854
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 50
    • 20444440706 scopus 로고    scopus 로고
    • Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation
    • Lee YS, Kim HK, Chung S, Kim KS, Dutta A (2005) Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation. J Biol Chem 280:16635-16641
    • (2005) J Biol Chem , vol.280 , pp. 16635-16641
    • Lee, Y.S.1    Kim, H.K.2    Chung, S.3    Kim, K.S.4    Dutta, A.5
  • 51
    • 34250637210 scopus 로고    scopus 로고
    • Function and localization of microRNAs in mammalian cells
    • Leung AK, Sharp PA (2006) Function and localization of microRNAs in mammalian cells. Cold Spring Harbor Symp Quant Biol 71:29-38
    • (2006) Cold Spring Harbor Symp Quant Biol , vol.71 , pp. 29-38
    • Leung, A.K.1    Sharp, P.A.2
  • 53
    • 35848966558 scopus 로고    scopus 로고
    • Human TRIM71 and its nematode homologue are targets of let-7 microRNA and its zebrafish orthologue is essential for development
    • Lin YC, Hsieh LC, Kuo MW, Yu J, Kuo HH, Lo WL, Lin RJ, Yu AL, Li WH (2007) Human TRIM71 and its nematode homologue are targets of let-7 microRNA and its zebrafish orthologue is essential for development. Mol Biol Evol 24:2525-2534
    • (2007) Mol Biol Evol , vol.24 , pp. 2525-2534
    • Lin, Y.C.1    Hsieh, L.C.2    Kuo, M.W.3    Yu, J.4    Kuo, H.H.5    Lo, W.L.6    Lin, R.J.7    Yu, A.L.8    Li, W.H.9
  • 55
    • 58049208169 scopus 로고    scopus 로고
    • The let-7 microRNA target gene, Mlin41/Trim71 is required for mouse embryonic survival and neural tube closure
    • (Georgetown, Tex
    • Maller Schulman BR, Liang X, Stahlhut C, DelConte C, Stefani G, Slack FJ (2008) The let-7 microRNA target gene, Mlin41/Trim71 is required for mouse embryonic survival and neural tube closure. Cell Cycle (Georgetown, Tex 7:3935-3942
    • (2008) Cell Cycle , vol.7 , pp. 3935-3942
    • Maller Schulman, B.R.1    Liang, X.2    Stahlhut, C.3    DelConte, C.4    Stefani, G.5    Slack, F.J.6
  • 57
    • 33947431322 scopus 로고    scopus 로고
    • Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
    • (New York, NY)
    • Mayr C, Hemann MT, Bartel DP (2007) Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science (New York, NY) 315:1576-1579
    • (2007) Science , vol.315 , pp. 1576-1579
    • Mayr, C.1    Hemann, M.T.2    Bartel, D.P.3
  • 58
    • 30444452500 scopus 로고    scopus 로고
    • TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases
    • Meroni G, Diez-Roux G (2005) TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases. Bioessays 27:1147-1157
    • (2005) Bioessays , vol.27 , pp. 1147-1157
    • Meroni, G.1    Diez-Roux, G.2
  • 59
    • 33845709215 scopus 로고    scopus 로고
    • Multiple mechanisms are involved in regulating the expression of the developmental timing regulator lin-28 in Caenorhabditis elegans
    • Morita K, Han M (2006) Multiple mechanisms are involved in regulating the expression of the developmental timing regulator lin-28 in Caenorhabditis elegans. EMBO J 25:5794-5804
    • (2006) EMBO J , vol.25 , pp. 5794-5804
    • Morita, K.1    Han, M.2
  • 60
    • 34249665533 scopus 로고    scopus 로고
    • Heterochronic genes and the nature of developmental time
    • Moss EG (2007) Heterochronic genes and the nature of developmental time. Curr Biol 17:R425-R434
    • (2007) Curr Biol , vol.17
    • Moss, E.G.1
  • 61
    • 0030970775 scopus 로고    scopus 로고
    • The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA
    • Moss EG, Lee RC, Ambros V (1997) The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell 88:637-646
    • (1997) Cell , vol.88 , pp. 637-646
    • Moss, E.G.1    Lee, R.C.2    Ambros, V.3
  • 63
    • 47949100595 scopus 로고    scopus 로고
    • Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
    • (New York, NY)
    • Newman MA, Thomson JM, Hammond SM (2008) Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA (New York, NY) 14:1539-1549
    • (2008) RNA , vol.14 , pp. 1539-1549
    • Newman, M.A.1    Thomson, J.M.2    Hammond, S.M.3
  • 64
    • 43049164296 scopus 로고    scopus 로고
    • A mis-expression study of factors affecting Drosophila PNS cell identity
    • O'Farrell F, Kylsten P (2008) A mis-expression study of factors affecting Drosophila PNS cell identity. Biochem Biophys Res Commun 370:657-662
    • (2008) Biochem Biophys Res Commun , vol.370 , pp. 657-662
    • O'Farrell, F.1    Kylsten, P.2
  • 65
    • 38149087481 scopus 로고    scopus 로고
    • Regulation of the Drosophila lin-41 homologue dappled by let-7 reveals conservation of a regulatory mechanism within the LIN-41 subclade
    • O'Farrell F, Esfahani SS, Engstrom Y, Kylsten P (2008) Regulation of the Drosophila lin-41 homologue dappled by let-7 reveals conservation of a regulatory mechanism within the LIN-41 subclade. Dev Dyn 237:196-208
    • (2008) Dev Dyn , vol.237 , pp. 196-208
    • O'Farrell, F.1    Esfahani, S.S.2    Engstrom, Y.3    Kylsten, P.4
  • 66
    • 44349084754 scopus 로고    scopus 로고
    • The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs
    • Okamura K, Chung WJ, Ruby JG, Guo H, Bartel DP, Lai EC (2008) The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs. Nature 453:803-806
    • (2008) Nature , vol.453 , pp. 803-806
    • Okamura, K.1    Chung, W.J.2    Ruby, J.G.3    Guo, H.4    Bartel, D.P.5    Lai, E.C.6
  • 69
    • 2542563401 scopus 로고    scopus 로고
    • The C. elegans heterochronic gene lin-46 affects developmental timing at two larval stages and encodes a relative of the scaffolding protein gephyrin
    • Pepper AS, McCane JE, Kemper K, Yeung DA, Lee RC, Ambros V, Moss EG (2004) The C. elegans heterochronic gene lin-46 affects developmental timing at two larval stages and encodes a relative of the scaffolding protein gephyrin. Development 131:2049-2059
    • (2004) Development , vol.131 , pp. 2049-2059
    • Pepper, A.S.1    McCane, J.E.2    Kemper, K.3    Yeung, D.A.4    Lee, R.C.5    Ambros, V.6    Moss, E.G.7
  • 71
    • 34247589770 scopus 로고    scopus 로고
    • Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency
    • Polesskaya A, Cuvellier S, Naguibneva I, Duquet A, Moss EG, Harel-Bellan A (2007) Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency. Genes Dev 21:1125-1138
    • (2007) Genes Dev , vol.21 , pp. 1125-1138
    • Polesskaya, A.1    Cuvellier, S.2    Naguibneva, I.3    Duquet, A.4    Moss, E.G.5    Harel-Bellan, A.6
  • 73
    • 0346250854 scopus 로고    scopus 로고
    • The transcriptome profile of human embryonic stem cells as defined by SAGE
    • (Dayton, Ohio)
    • Richards M, Tan SP, Tan JH, Chan WK, Bongso A (2004) The transcriptome profile of human embryonic stem cells as defined by SAGE. Stem Cells (Dayton, Ohio) 22:51-64
    • (2004) Stem Cells , vol.22 , pp. 51-64
    • Richards, M.1    Tan, S.P.2    Tan, J.H.3    Chan, W.K.4    Bongso, A.5
  • 74
    • 26244440240 scopus 로고    scopus 로고
    • Intrinsic and extrinsic regulators of developmental timing: From miRNAs to nutritional cues
    • Rougvie AE (2005) Intrinsic and extrinsic regulators of developmental timing: From miRNAs to nutritional cues. Development 132:3787-3798
    • (2005) Development , vol.132 , pp. 3787-3798
    • Rougvie, A.E.1
  • 75
    • 52949091534 scopus 로고    scopus 로고
    • The let-7 family of microRNAs
    • Roush S, Slack FJ (2008) The let-7 family of microRNAs. Trends Cell Biol 18:505-516
    • (2008) Trends Cell Biol , vol.18 , pp. 505-516
    • Roush, S.1    Slack, F.J.2
  • 76
    • 33845436047 scopus 로고    scopus 로고
    • Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans
    • Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP (2006) Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans. Cell 127:1193-1207
    • (2006) Cell , vol.127 , pp. 1193-1207
    • Ruby, J.G.1    Jan, C.2    Player, C.3    Axtell, M.J.4    Lee, W.5    Nusbaum, C.6    Ge, H.7    Bartel, D.P.8
  • 77
    • 53549133101 scopus 로고    scopus 로고
    • The perfect storm of tiny RNAs
    • Ruvkun G (2008) The perfect storm of tiny RNAs. Nat Med 14:1041-1045
    • (2008) Nat Med , vol.14 , pp. 1041-1045
    • Ruvkun, G.1
  • 78
    • 2142765354 scopus 로고    scopus 로고
    • The 20 years it took to recognize the importance of tiny RNAs
    • 92 p following S96
    • Ruvkun G, Wightman B, Ha I (2004) The 20 years it took to recognize the importance of tiny RNAs. Cell 116:S93-S96 92 p following S96
    • (2004) Cell , vol.116
    • Ruvkun, G.1    Wightman, B.2    Ha, I.3
  • 79
    • 48649103982 scopus 로고    scopus 로고
    • A feedback loop comprising lin-28 and let-7 controls pre- let-7 maturation during neural stem-cell commitment
    • Rybak A, Fuchs H, Smirnova L, Brandt C, Pohl EE, Nitsch R, Wulczyn FG (2008) A feedback loop comprising lin-28 and let-7 controls pre- let-7 maturation during neural stem-cell commitment. Nat Cell Biol 10:987-993
    • (2008) Nat Cell Biol , vol.10 , pp. 987-993
    • Rybak, A.1    Fuchs, H.2    Smirnova, L.3    Brandt, C.4    Pohl, E.E.5    Nitsch, R.6    Wulczyn, F.G.7
  • 80
    • 46249092601 scopus 로고    scopus 로고
    • Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites
    • (New York, NY)
    • Sandberg R, Neilson JR, Sarma A, Sharp PA, Burge CB (2008) Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites. Science (New York, NY) 320:1643-1647
    • (2008) Science , vol.320 , pp. 1643-1647
    • Sandberg, R.1    Neilson, J.R.2    Sarma, A.3    Sharp, P.A.4    Burge, C.B.5
  • 81
    • 28444475503 scopus 로고    scopus 로고
    • Reciprocal expression of lin-41 and the microRNAs let-7 and mir-125 during mouse embryogenesis
    • Schulman BR, Esquela-Kerscher A, Slack FJ (2005) Reciprocal expression of lin-41 and the microRNAs let-7 and mir-125 during mouse embryogenesis. Dev Dyn 234:1046-1054
    • (2005) Dev Dyn , vol.234 , pp. 1046-1054
    • Schulman, B.R.1    Esquela-Kerscher, A.2    Slack, F.J.3
  • 82
    • 61349191567 scopus 로고    scopus 로고
    • The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors
    • Schwamborn JC, Berezikov E, Knoblich JA (2009) The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell 136:913-925
    • (2009) Cell , vol.136 , pp. 913-925
    • Schwamborn, J.C.1    Berezikov, E.2    Knoblich, J.A.3
  • 83
    • 0037085968 scopus 로고    scopus 로고
    • Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation
    • Seggerson K, Tang L, Moss EG (2002) Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation. Dev Biol 243:215-225
    • (2002) Dev Biol , vol.243 , pp. 215-225
    • Seggerson, K.1    Tang, L.2    Moss, E.G.3
  • 84
    • 0036535323 scopus 로고    scopus 로고
    • The expression of the let-7 small regulatory RNA is controlled by ecdysone during metamorphosis in Drosophila melanogaster
    • Sempere LF, Dubrovsky EB, Dubrovskaya VA, Berger EM, Ambros V (2002) The expression of the let-7 small regulatory RNA is controlled by ecdysone during metamorphosis in Drosophila melanogaster. Dev Biol 244:170-179
    • (2002) Dev Biol , vol.244 , pp. 170-179
    • Sempere, L.F.1    Dubrovsky, E.B.2    Dubrovskaya, V.A.3    Berger, E.M.4    Ambros, V.5
  • 85
    • 0037790717 scopus 로고    scopus 로고
    • Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity
    • Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V (2003) Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity. Dev Biol 259:9-18
    • (2003) Dev Biol , vol.259 , pp. 9-18
    • Sempere, L.F.1    Sokol, N.S.2    Dubrovsky, E.B.3    Berger, E.M.4    Ambros, V.5
  • 86
    • 1942494040 scopus 로고    scopus 로고
    • Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation
    • Sempere LF, Freemantle S, Pitha-Rowe I, Moss E, Dmitrovsky E, Ambros V (2004) Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biology 5:R13
    • (2004) Genome Biology , vol.5
    • Sempere, L.F.1    Freemantle, S.2    Pitha-Rowe, I.3    Moss, E.4    Dmitrovsky, E.5    Ambros, V.6
  • 87
    • 0035281741 scopus 로고    scopus 로고
    • RNA interference - 02001
    • Sharp PA (2001) RNA interference - 2001. Genes Dev 15:485-490
    • (2001) Genes Dev , vol.15 , pp. 485-490
    • Sharp, P.A.1
  • 88
    • 0031468448 scopus 로고    scopus 로고
    • Temporal pattern formation by heterochronic genes
    • Slack F, Ruvkun G (1997) Temporal pattern formation by heterochronic genes. Annu Rev Genet 31:611-634
    • (1997) Annu Rev Genet , vol.31 , pp. 611-634
    • Slack, F.1    Ruvkun, G.2
  • 89
    • 33646780266 scopus 로고    scopus 로고
    • MicroRNAs as a potential magic bullet in cancer
    • (London, England)
    • Slack FJ, Weidhaas JB (2006) MicroRNAs as a potential magic bullet in cancer. Future Oncol (London, England) 2:73-82
    • (2006) Future Oncol , vol.2 , pp. 73-82
    • Slack, F.J.1    Weidhaas, J.B.2
  • 90
    • 0033634943 scopus 로고    scopus 로고
    • The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
    • Slack FJ, Basson M, Liu Z, Ambros V, Horvitz HR, Ruvkun G (2000) The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol Cell 5:659-669
    • (2000) Mol Cell , vol.5 , pp. 659-669
    • Slack, F.J.1    Basson, M.2    Liu, Z.3    Ambros, V.4    Horvitz, H.R.5    Ruvkun, G.6
  • 92
    • 45349099216 scopus 로고    scopus 로고
    • Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis
    • Sokol NS, Xu P, Jan YN, Ambros V (2008) Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis. Genes Dev 22:1591-1596
    • (2008) Genes Dev , vol.22 , pp. 1591-1596
    • Sokol, N.S.1    Xu, P.2    Jan, Y.N.3    Ambros, V.4
  • 93
    • 39749110083 scopus 로고    scopus 로고
    • Small non-coding RNAs in animal development
    • Stefani G, Slack FJ (2008) Small non-coding RNAs in animal development. Nat Rev Mol Cell Biol 9:219-230
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 219-230
    • Stefani, G.1    Slack, F.J.2
  • 94
    • 0017618537 scopus 로고
    • Post-embryonic cell lineages of the nematode, Caenorhabditis elegans
    • Sulston JE, Horvitz HR (1977) Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. Dev Biol 56:110-156
    • (1977) Dev Biol , vol.56 , pp. 110-156
    • Sulston, J.E.1    Horvitz, H.R.2
  • 95
    • 0018962395 scopus 로고
    • The Caenorhabditis elegans male: Postembryonic development of nongonadal structures
    • Sulston JE, Albertson DG, Thomson JN (1980) The Caenorhabditis elegans male: Postembryonic development of nongonadal structures. Dev Biol 78:542-576
    • (1980) Dev Biol , vol.78 , pp. 542-576
    • Sulston, J.E.1    Albertson, D.G.2    Thomson, J.N.3
  • 98
    • 13944262052 scopus 로고    scopus 로고
    • A custom microarray platform for analysis of microRNA gene expression
    • Thomson JM, Parker J, Perou CM, Hammond SM (2004) A custom microarray platform for analysis of microRNA gene expression. Nat Methods 1:47-53
    • (2004) Nat Methods , vol.1 , pp. 47-53
    • Thomson, J.M.1    Parker, J.2    Perou, C.M.3    Hammond, S.M.4
  • 100
    • 33947262696 scopus 로고    scopus 로고
    • AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2
    • Vasudevan S, Steitz JA (2007) AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2. Cell 128:1105-1118
    • (2007) Cell , vol.128 , pp. 1105-1118
    • Vasudevan, S.1    Steitz, J.A.2
  • 101
    • 36749026906 scopus 로고    scopus 로고
    • Switching from repression to activation: microRNAs can up-regulate translation
    • (New York, NY)
    • Vasudevan S, Tong Y, Steitz JA (2007) Switching from repression to activation: MicroRNAs can up-regulate translation. Science (New York, NY) 318:1931-1934
    • (2007) Science , vol.318 , pp. 1931-1934
    • Vasudevan, S.1    Tong, Y.2    Steitz, J.A.3
  • 102
    • 45849091123 scopus 로고    scopus 로고
    • Cell-cycle control of microRNA-mediated translation regulation
    • (Georgetown, Tex)
    • Vasudevan S, Tong Y, Steitz JA (2008) Cell-cycle control of microRNA-mediated translation regulation. Cell Cycle (Georgetown, Tex) 7:1545-1549
    • (2008) Cell Cycle , vol.7 , pp. 1545-1549
    • Vasudevan, S.1    Tong, Y.2    Steitz, J.A.3
  • 103
    • 0942301280 scopus 로고    scopus 로고
    • The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3′ UTR
    • Vella MC, Choi EY, Lin SY, Reinert K, Slack FJ (2004a) The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3′ UTR. Genes Dev 18:132-137
    • (2004) Genes Dev , vol.18 , pp. 132-137
    • Vella, M.C.1    Choi, E.Y.2    Lin, S.Y.3    Reinert, K.4    Slack, F.J.5
  • 104
    • 10644253787 scopus 로고    scopus 로고
    • Architecture of a validated microRNA: Target interaction
    • Vella MC, Reinert K, Slack FJ (2004b) Architecture of a validated microRNA: Target interaction. Chem Biol 11:1619-1623
    • (2004) Chem Biol , vol.11 , pp. 1619-1623
    • Vella, M.C.1    Reinert, K.2    Slack, F.J.3
  • 105
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
    • Visvader JE, Lindeman GJ (2008) Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev 8:755-768
    • (2008) Nat Rev , vol.8 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 106
    • 40849108663 scopus 로고    scopus 로고
    • Selective blockade of microRNA processing by Lin28
    • (New York, NY)
    • Viswanathan SR, Daley GQ, Gregory RI (2008) Selective blockade of microRNA processing by Lin28. Science (New York, NY) 320:97-100
    • (2008) Science , vol.320 , pp. 97-100
    • Viswanathan, S.R.1    Daley, G.Q.2    Gregory, R.I.3
  • 107
    • 33847323881 scopus 로고    scopus 로고
    • DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal
    • Wang Y, Medvid R, Melton C, Jaenisch R, Blelloch R (2007) DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat Genet 39:380-385
    • (2007) Nat Genet , vol.39 , pp. 380-385
    • Wang, Y.1    Medvid, R.2    Melton, C.3    Jaenisch, R.4    Blelloch, R.5
  • 109
    • 27144475302 scopus 로고    scopus 로고
    • Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells
    • Wu L, Belasco JG (2005) Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells. Mol Cell Biol 25:9198-9208
    • (2005) Mol Cell Biol , vol.25 , pp. 9198-9208
    • Wu, L.1    Belasco, J.G.2
  • 111
    • 60849116964 scopus 로고    scopus 로고
    • Lin28 modulates cell growth and associates with a subset of cell cycle regulator mRNAs in mouse embryonic stem cells
    • (New York, NY)
    • Xu B, Zhang K, Huang Y (2009) Lin28 modulates cell growth and associates with a subset of cell cycle regulator mRNAs in mouse embryonic stem cells. RNA (New York, NY) 15:357-361
    • (2009) RNA , vol.15 , pp. 357-361
    • Xu, B.1    Zhang, K.2    Huang, Y.3
  • 112
    • 0344013522 scopus 로고    scopus 로고
    • Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse
    • Yang DH, Moss EG (2003) Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse. Gene Expr Patterns 3:719-726
    • (2003) Gene Expr Patterns , vol.3 , pp. 719-726
    • Yang, D.H.1    Moss, E.G.2


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