The expression of the let-7 small regulatory RNA is controlled by ecdysone during metamorphosis in Drosophila melanogaster

Developmental Biology

Volumn 244, Issue 1, 2002, Pages 170-179

  Sempere, Lorenzo F ^a   Dubrovsky, Edward B ^b   Dubrovskaya, Veronica A ^b   Berger, Edward M ^b   Ambros, Victor ^a  

^a DARTMOUTH COLLEGE   (United States)

^b Lamont Doherty Earth Observatory   (United States)

Author keywords

Ecdysone; Heterochronic genes; Let 7; Metamorphosis

Indexed keywords

ECDYSONE; GENE PRODUCT; PROTEIN BR C; PROTEIN LET 7; RNA; STEROID HORMONE; UNCLASSIFIED DRUG;

ARTICLE; CAENORHABDITIS ELEGANS; CELL CULTURE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; GENE CONTROL; GENE EXPRESSION; HORMONAL REGULATION; INSECT DEVELOPMENT; INVERTEBRATE; LARVA; METAMORPHOSIS; NONHUMAN; NORTHERN BLOTTING; ORGAN CULTURE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALIA; CAENORHABDITIS; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; HEXAPODA; INVERTEBRATA; MELANOGASTER;

EID: 0036535323     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2002.0594     Document Type: Article

References (54)

1. A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans
2. Control of developmental timing in Caenorhabditis elegans
3. Heterochronic genes and the temporal control of C. elegans development
4. Methods in quantitative analysis of transcription in larvae and prepupae
5. daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans
6. Mutations in the beta-propeller domain of the Drosophila brain tumor (brat) protein induce neoplasm in the larval brain
7. Temporal control of puffing activity in polytene chromosomes
8. A switch in broad-complex zinc-finger isoform expression is regulated post-transcriptionally during the metamorphosis of Drosophila imaginal discs
9. Cytogenetic analysis of the 2B3-4-2B11 region of the X chromosome of Drosophila melanogaster. II. Changes in 20-OH ecdysone puffing caused by genetic defects of puff 2B5
10. The Drosophila 74EF early puff contains E74, a complex ecdysone-inducible gene that encodes two ets-related proteins
11. The effects of ecdysteroid hormones on Drosophila melanogaster cell lines
12. Cell culture
13. Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways
14. The Drosophila Broad-Complex early gene directly regulates late gene transcription during the ecdysone-induced puffing cascade
15. The Drosophila Broad-Complex encodes a family of related proteins containing zinc fingers
16. The Broad-Complex gene is a tissue-specific modulator of the ecdysone response of the Drosophila hsp23 gene
17. Selective binding of Drosophila BR-C isoforms to a distal regulatory element in the hsp23 promoter
18. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
19. Isolation, regulation, and DNA-binding properties of three Drosophila nuclear hormone receptor superfamily members
20. Roles of ecdysone in Drosophila development
21. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
22. A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation
23. A cellular function for the RNA-interference enzyme dicer in the maturation of the let-7 small temporal RNA
24. The Drosophila Broad-Complex plays a key role in controlling ecdysone- regulated gene expression at the onset of metamorphosis
25. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
26. The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA
27. The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation
28. Genetic studies of mei-P26 reveal a link between the processes that control germ cell proliferation in both sexes and those that control meiotic exchange in Drosophila
29. Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
30. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
31. The radioimmune assay of ecdysteroid titres in Drosophila melanogaster
32. The ecdysone regulatory cascades in Drosophila
33. Hormones and Drosophila development
34. Identification of immune system and response genes, and novel mutations causing melanotic tumor formation in Drosophila melanogaster
35. The Caenorhabditis elegans heterochronic gene lin-14 encodes a nuclear protein that forms a temporal developmental switch
36. The E75 ecdysone-inducible gene responsible for the 75B early puff in Drosophila encodes two new members of the steroid receptor superfamily
37. Temporal pattern formation by heterochronic genes
38. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
39. A novel repeat domain that is often associated with RING finger and B- box motifs
40. Nuclear receptors in nematodes: Themes and variations
41. Drosophila Brain Tumor is a translational repressor
42. Post-embryonic cell lineages of the nematode, Caenorhabditis elegans
43. Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle
44. Spatial and temporal patterns of E74 transcription during Drosophila development
45. From embryogenesis to metamorphosis: The regulation and function of Drosophila nuclear receptor superfamily members
46. Files on steroids - Drosophila metamorphosis and the mechanisms of steroid hormone action
47. Molecular analysis of a steroid-induced regulatory hierarchy: The Drosophila E74A protein directly regulates L71-6 transcription
48. Steroid and high-temperature induction of the small heat-shock protein genes in Drosophila
49. The Broad Complex directly controls a tissue specific response to the steroid hormone ecdysone at the onset of Drosophila metamorphosis
50. Functional ecdysone receptor is the product of EcR and Ultraspiracle genes
51. Method of selection of synchronously developing larvae of Drosophila melanogaster
52. Cytogenetic analysis of the 2B3-4-2B11 region of the X chromosome of Drosophila melanogaster. III. Puffing disturbance in salivary gland chromosomes of homozygotes for mutation 1(1)pp1t10