Regulation of the Drosophila lin-41 homologue dappled by let-7 reveals conservation of a regulatory mechanism within the LIN-41 subclade

Developmental Dynamics

Volumn 237, Issue 1, 2008, Pages 196-208

  O'Farrell, Fergal ^a,b   Esfahani, Shiva Seyedoleslami ^c   Engström, Ylva ^c   Kylsten, Per ^a  

^a SÖDERTÖRN UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

dappled; Drosophila; let 7; LIN 41; miRNA; RBCC TRIM

Indexed keywords

MICRORNA;

ARTICLE; DAPPLED GENE; DROSOPHILA; EYE DEVELOPMENT; EYE MALFORMATION; GENE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENETIC REGULATION; INSECT GENETICS; LET 7 GENE; LIN 41 GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REGULATORY MECHANISM; RNA ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELLS, CULTURED; DROSOPHILA; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; METALLOPROTEINS; MICRORNAS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; PHYLOGENY; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 38149087481     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.21396     Document Type: Article

References (46)

1. Arama E, Dickman D, Kimchie Z, Shearn A, Lev Z. 2000. Mutations in the beta-propeller domain of the Drosophila brain tumor (brat) protein induce neoplasm in the larval brain. Oncogene 19:3706-3716.
2. Bartel DP. 2004. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281-297.
3. Bashirullah A, Pasquinelli AE, Kiger AA, Perrimon N, Ruvkun G, Thummel CS. 2003. Coordinate regulation of small temporal RNAs at the onset of Drosophila metamorphosis. Dev Biol 259:1-8.
4. Bello B, Reichert H, Hirth F. 2006. The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila. Development 133:2639-2648.
5. Betschinger J, Mechtler K, Knoblich JA. 2006. Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells. Cell 124:1241-1253.
6. Brachmann CB, Cagan RL. 2003. Patterning the fly eye: the role of apoptosis. Trends Genet 19:91-96.
7. Brand AH, Perrimon N. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118:401-415.
8. Brody T, Stivers C, Nagle J, Odenwald WF. 2002. Identification of novel Drosophila neural precursor genes using a differential embryonic head cDNA screen. Mech Dev 113:41-59.
9. Burgler C, Macdonald PM. 2005. Prediction and verification of microRNA targets by MovingTargets, a highly adaptable prediction method. BMC Genomics 6:88.
10. Campos-Ortega JA, Hartenstein V. 1985. The embryonic development of Drosophila melanogaster. Berlin, Heidelberg: Springer Verlag.
11. Chien CT, Wang S, Rothenberg M, Jan LY, Jan YN. 1998. Numb-associated kinase interacts with the phosphotyrosine binding domain of Numb and antagonizes the function of Numb in vivo. Mol Cell Biol 18:598-607.
12. Edwards TA, Wilkinson BD, Wharton RP, Aggarwal AK. 2003. Model of the brain tumor-Pumilio translation repressor complex. Genes Dev 17:2508-2513.
13. Enright AJ, John B, Gaul U, Tuschl T, Sander C, Marks DS. 2003. MicroRNA targets in Drosophila. Genome Biol 5:R1.
14. Frank DJ, Edgar BA, Roth MB. 2002. The Drosophila melanogaster gene brain tumor negatively regulates cell growth and ribosomal RNA synthesis. Development 129:399-407.
15. Freeman M. 1996. Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye. Cell 87:651-660.
16. Freeman M. 1997. Cell determination strategies in the Drosophila eye. Development 124:261-270.
17. Gallio M, Englund C, Kylsten P, Samakovlis C. 2004. Rhomboid 3 orchestrates Slit-independent repulsion of tracheal branches at the CNS midline. Development 131:3605-3614.
18. Gudgen M, Chandrasekaran A, Frazier T, Boyd L. 2004. Interactions within the ubiquitin pathway of Caenorhabditis elegans. Biochem Biophys Res Commun 325:479-486.
19. Horn EJ, Albor A, Liu Y, El-Hizawi S, Vanderbeek GE, Babcock M, Bowden GT, Hennings H, Lozano G, Weinberg WC, Kulesz-Martin M. 2004. RING protein Trim32 associated with skin carcinogenesis has anti-apoptotic and E3-ubiquitin ligase properties. Carcinogenesis 25:157-167.
20. Hoskins RA, Nelson CR, Berman BP, Laverty TR, George RA, Ciesiolka L, Naeemuddin M, Arenson AD, Durbin J, David RG, Tabor PE, Bailey MR, DeShazo DR, Catanese J, Mammoser A, Osoegawa K, de Jong PJ, Celniker SE, Gibbs RA, Rubin GM, Scherer SE. 2000. A BAC-based physical map of the major autosomes of Drosophila melanogaster. Science 287:2271-2274.
21. Kanamoto T, Terada K, Yoshikawa H, Furukawa T. 2006. Cloning and regulation of the vertebrate homologue of lin-41 that functions as a heterochronic gene in Caenorhabditis elegans. Dev Dyn 235:1142-1149.
22. Lancman JJ, Caruccio NC, Harfe BD, Pasquinelli AE, Schageman JJ, Pertsemlidis A, Fallon JF. 2005. Analysis of the regulation of lin-41 during chick and mouse limb development. Dev Dyn 234:948-960.
23. Lee RC, Feinbaum RL, Ambros V. 1993. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75:843-854.
24. Lee CY, Wilkinson BD, Siegrist SE, Wharton RP, Doe CQ. 2006. Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal. Dev Cell 10:441-449.
25. Loop T, Leemans R, Stiefel U, Hermida L, Egger B, Xie F, Primig M, Certa U, Fischbach KF, Reichert H, Hirth F. 2004. Transcriptional signature of an adult brain tumor in Drosophila. BMC Genomics 5:24.
26. McKay SJ, Johnsen R, Khattra J, Asano J, Baillie DL, Chan S, Dube N, Fang L, Goszczynski B, Ha E, Halfnight E, Hollebakken R, Huang P, Hung K, Jensen V, Jones SJ, Kai H, Li D, Mah A, Marra M, McGhee J, Newbury R, Pouzyrev A, Riddle DL, Sonnhammer E, Tian H, Tu D, Tyson JR, Vatcher G, Warner A, Wong K, Zhao Z, Moerman DG. 2003. Gene expression profiling of cells, tissues, and developmental stages of the nematode C. elegans. Cold Spring Harb Symp Quant Biol 68:159-169.
27. Meroni G, Diez-Roux G. 2005. TRIM/RBCC, a novel class of "single protein RING finger" E3 ubiquitin ligases. Bioessays 27:1147-1157.
28. Page SL, McKim KS, Deneen B, Van Hook TL, Hawley RS. 2000. Genetic studies of mei-P26 reveal a link between the processes that control germ cell proliferation in both sexes and those that control meiotic exchange in Drosophila. Genetics 155:1757-1772.
29. Pasquinelli AE, Reinhart BJ, Slack F, Martindale MQ, Kuroda MI, Maller B, Hayward DC, Ball EE, Degnan B, Muller P, Spring J, Srinivasan A, Fishman M, Finnerty J, Corbo J, Levine M, Leahy P, Davidson E, Ruvkun G. 2000. Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature 408:86-89.
30. Pasquinelli AE, McCoy A, Jimenez E, Salo E, Ruvkun G, Martindale MQ, Baguna J. 2003. Expression of the 22 nucleotide let-7 heterochronic RNA throughout the Metazoa: a role in life history evolution? Evol Dev 5:372-378.
31. Petersen UM, Bjorklund G, Ip YT, Engstrom Y. 1995. The dorsal-related immunity factor, Dif, is a sequence-specific trans-activator of Drosophila Cecropin gene expression. EMBO J 14:3146-3158.
32. Ready DF, Hanson TE, Benzer S. 1976. Development of the Drosophila retina, a neurocrystalline lattice. Dev Biol 53:217-240.
33. Rehmsmeier M, Steffen P, Hochsmann M, Giegerich R. 2004. Fast and effective prediction of microRNA/target duplexes. RNA 10:1507-1517.
34. Reinhart BJ, Slack FJ, Basson M, Pasquinelli AE, Bettinger JC, Rougvie AE, Horvitz HR, Ruvkun G. 2000. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 403:901-906.
35. Rodriguez A, Zhou Z, Tang ML, Meller S, Chen J, Bellen H, Kimbrell DA. 1996. Identification of immune system and response genes, and novel mutations causing melanotic tumor formation in Drosophila melanogaster. Genetics 143:929-940.
36. Ryder E, Blows F, Ashburner M, Bautista-Llacer R, Coulson D, Drummond J, Webster J, Gubb D, Gunton N, Johnson G, O'Kane CJ, Huen D, Sharma P, Asztalos Z, Baisch H, Schulze J, Kube M, Kittlaus K, Reuter G, Maroy P, Szidonya J, Rasmuson-Lestander A, Ekstrom K, Dickson B, Hugentobler C, Stocker H, Hafen E, Lepesant JA, Pflugfelder G, Heisenberg M, Mechler B, Serras F, Corominas M, Schneuwly S, Preat T, Roote J, Russell S. 2004. The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster. Genetics 167:797-813.
37. Sakuma R, Noser JA, Ohmine S, Ikeda Y. 2007. Rhesus monkey TRIM5alpha restricts HIV-1 production through rapid degradation of viral Gag polyproteins. Nat Med 13:631-635.
38. Schulman BR, Esquela-Kerscher A, Slack FJ. 2005. Reciprocal expression of lin-41 and the microRNAs let-7 and mir-125 during mouse embryogenesis. Dev Dyn 234:1046-1054.
39. Selleck SB, Steller H. 1991. The influence of retinal innervation on neurogenesis in the first optic ganglion of Drosophila. Neuron 6:83-99.
40. Sempere LF, Dubrovsky EB, Dubrovskaya VA, Berger EM, Ambros V. 2002. The expression of the let-7 small regulatory RNA is controlled by ecdysone during metamorphosis in Drosophila melanogaster. Dev Biol 244:170-179.
41. Slack FJ, Ruvkun G. 1998. A novel repeat domain that is often associated with RING finger and B-box motifs. Trends Biochem Sci 23:474-475.
42. Slack FJ, Basson M, Liu Z, Ambros V, Horvitz HR, Ruvkun G. 2000. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol Cell 5:659-669.
43. Sonoda J, Wharton RP. 2001. Drosophila Brain Tumor is a translational repressor. Genes Dev 15:762-773.
44. Tomancak P, Beaton A, Weiszmann R, Kwan E, Shu S, Lewis SE, Richards S, Ashburner M, Hartenstein V, Celniker SE, Rubin GM. 2002. Systematic determination of patterns of gene expression during Drosophila embryogenesis. Genome Biol 3:RESEARCH0088.0081-0014.
45. Torok M, Etkin LD. 2001. Two B or not two B? Overview of the rapidly expanding B-box family of proteins. Differentiation 67:63-71.
46. Woodhouse E, Hersperger E, Shearn A. 1998. Growth, metastasis, and invasiveness of Drosophila tumors caused by mutations in specific tumor suppressor genes. Dev Genes Evol 207:542-550.