Regulation of CYP1A1 by heavy metals and consequences for drug metabolism

Expert Opinion on Drug Metabolism and Toxicology

Volumn 5, Issue 5, 2009, Pages 501-521

  Anwar Mohamed, Anwar ^a   Elbekai, Reem H ^a   El Kadi, Ayman O S ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Aryl hydrocarbon receptor; CYP1A1; Drug metabolism; Heavy metals

Indexed keywords

2 (4 AMINO 3 METHYLPHENYL)BENZOTHIAZOLE; AFP 464; AMIODARONE; AROMATIC HYDROCARBON RECEPTOR; ARSENIC; BERGAMOTTIN; CADMIUM; CHROMIUM; CIPROFIBRATE; CLOFIBRATE; COPPER; CURCUMIN; CYTOCHROME P450 1A1; CYTOTOXIC AGENT; DEXAMETHASONE; ELLIPTICINE; ESTRADIOL; FLUOROURACIL; FLUTAMIDE; FLUVOXAMINE; KETOCONAZOLE; LANSOPRAZOLE; LEAD; MERCURY; NORFLUOXETINE; OLTIPRAZ; OMEPRAZOLE; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VANADIUM;

DRUG METABOLISM; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME REGULATION; ENZYME REPRESSION; HUMAN; NONHUMAN; REVIEW; XENOBIOTIC METABOLISM;

ANIMALS; CYTOCHROME P-450 CYP1A1; DRUG INTERACTIONS; ENZYME INDUCTION; ENZYME INHIBITORS; HUMANS; METALS, HEAVY; PHARMACEUTICAL PREPARATIONS; PRODRUGS; SPECIES SPECIFICITY;

EID: 67649373380     PISSN: 17425255     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425250902918302     Document Type: Review

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