Monitoring expression of genes involved in drug metabolism and toxicology using DNA microarrays

Physiological Genomics

Volumn 2001, Issue 5, 2001, Pages 161-170

  Gerhold, David ^a   Lu, Meiqing ^a   Xu, Jian ^a   Austin, Christopher ^a   Caskey, C Thomas ^a   Rushmore, Thomas ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Cytochrome P 450; DNA microarray; Drug metabolism; Gene regulation

Indexed keywords

ANIMALIA;

3 METHYLCHOLANTHRENE; CLOFIBRATE; CYTOCHROME P450; DEXAMETHASONE; MESSENGER RNA; PHENOBARBITAL; XENOBIOTIC AGENT;

ANIMAL; ARTICLE; BIOSYNTHESIS; DNA MICROARRAY; DRUG EFFECT; DRUG SCREENING; ENERGY METABOLISM; ENZYMOLOGY; EVALUATION; GENE EXPRESSION PROFILING; GENETICS; LIVER; MALE; METHODOLOGY; RAT; REPRODUCIBILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SPRAGUE DAWLEY RAT; STRESS; TRANSACTIVATION;

ANIMALS; CLOFIBRATE; CYTOCHROME P-450 ENZYME SYSTEM; DEXAMETHASONE; DRUG EVALUATION, PRECLINICAL; ENERGY METABOLISM; GENE EXPRESSION PROFILING; LIVER; MALE; METHYLCHOLANTHRENE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOBARBITAL; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY; STRESS; TRANS-ACTIVATION (GENETICS); XENOBIOTICS;

EID: 0346942394     PISSN: 15312267     EISSN: None     Source Type: Journal    
DOI: 10.1152/physiolgenomics.2001.5.4.161     Document Type: Article

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