Inhibition of aryl hydrocarbon-induced cytochrome P-450 1A1 enzyme activity and CYP1A1 expression by resveratrol

Molecular Pharmacology

Volumn 56, Issue 4, 1999, Pages 760-767

  Ciolino, Henry P ^a   Yeh, Grace Chao ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ETHOXYRESORUFIN DEETHYLASE; PHENACETIN O DEETHYLASE; RESVERATROL;

ARTICLE; BREAST CARCINOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANTICARCINOGENIC AGENTS; BENZO(A)PYRENE; CARCINOGENS; CYTOCHROME P-450 CYP1A1; ENZYME ACTIVATION; ENZYME INHIBITORS; GENE EXPRESSION; HUMANS; RECEPTORS, ARYL HYDROCARBON; STILBENES; TUMOR CELLS, CULTURED;

EID: 0032862195     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
2. Chae YH, Marcus CB, Ho DK, Cassady JM and Baird WM (1991) Effects of synthetic and naturally occurring flavonoids on benzo[a]pyrene metabolism by hepatic microsomes prepared from rats treated with cytochrome P-450 inducers. Cancer Lett 60:15-24.
3. Chen YH and Tukey RH (1996) Protein kinase C modulates regulation of the CYP1A1 gene by the aryl hydrocarbon receptor. J Biol Chem 271:26261-26266.
4. Christou M, Mitchell MJ, Aoyama T, Gelboin HV, Gonzalez FJ and Jefcoate CR (1992) Selective suppression of the catalytic activity of cDNA-expressed cytochrome P4502B1 toward polycyclic hydrocarbons in the microsomal membrane: Modification of this effect by specific amino acid substitutions. Biochemistry 31: 2835-41.
5. Chung I and Bresnick E (1994) 3-Methylcholanthrene-mediated induction of cytochrome P4501A2 in human hepatoma HepG2 cells as quantified by the reverse transcription-polymerase chain reaction. Arch Biochem Biophys 314:75-81.
6. Ciolino HP, Daschner PJ, Wang TT and Yeh GC (1998a) Effect of curcumin on the aryl hydrocarbon receptor and cytochrome P450 1A1 in MCF-7 human breast carcinoma cells. Biochem Pharmacol 56:197-206.
7. Ciolino HP, Daschner PJ and Yeh GC (1998b) Resveratrol inhibits transcription of CYP1A1 in vitro by preventing activation of the aryl hydrocarbon receptor. Cancer Res 58:5707-5712.
8. Constant J (1997) Alcohol, ischemic heart disease, and the French paradox. Coron Artery Dis 8:645-649.
9. Denison MS, Fisher JM and Whitlock JP Jr (1988) The DNA recognition site for the dioxin-Ah receptor complex: Nucleotide sequence and functional analysis. J Biol Chem 263:17221-17224.
10. Dertinger SD, Silverstone AE and Gasiewicz TA (1998) Influence of aromatic hydrocarbon receptor-mediated events on the genotoxicity of cigarette smoke condensate. Carcinogenesis 19:2037-2042.
11. Dohr O, Vogel C and Abel J (1995) Different response of 2,3,7,8-tetrachlorodibenzo-p-dioxin [TCDD]-sensitive genes in human breast cancer MCF-7 and MDA-MB 231 cells. Arch Biochem Biophys 321:405-412.
12. Grove AD, Kessler FK, Metz RP and Ritter JK (1997) Identification of a rat oltipraz-inducible UDP-glucuronosyltransferase (UGT1A7) with activity towards benzo-(a)pyrene-7,8-dihydrodiol. J Biol Chem 272:1621-1627.
13. Guengerich FP and Shimada T (1998) Activation of procarcinogens by human cytochrome P450 enzymes. Mutat Res 400:201-213.
14. Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CW, Fong HH, Farnsworth NH, Kinghorn AD, Mehta RG, Moon RC and Pezzuto JM (1997) Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science (Wash DC) 275:218-220.
15. Kellermann G, Shaw CR and Luyten-Kellermann M (1973) Aryl hydrocarbon hydroxylase inducibility and bronchogenic carcinoma. N Engl J Med 289:934-937.
16. Kennedy S and Jones S (1994) Simultaneous measurement of cytochrome P4501A catalytic activity and total protein concentration with a fluorescence plate reader. Anal Biochem 222:217-223.
17. Kouri RE, McKinney CE, Slomiany DJ, Snodgrass DR, Wray NP and McLemore TL (1982) Positive correlation between high aryl hydrocarbon hydroxylase activity and primary lung cancer as analyzed in cryopreserved lymphocytes. Cancer Res 42:5030-5037.
18. Kress S and Greenlee WF (1997) Cell-specific regulation of human CYP1A1 and CYP1B1 genes. Cancer Res 57:1264-1269.
19. Larsen MC, Angus WG, Brake PB, Eltom SE, Sukow KA and Jefcoate CR (1998) Characterization of CYP1B1 and CYP1A1 expression in human mammary epithelial cells: Role of the aryl hydrocarbon receptor in polycyclic aromatic hydrocarbon metabolism. Cancer Res 58:2366-2374.
20. Lijinsky W (1991) The formation and occurrence of polynuclear aromatic hydrocarbons associated with food. Mutat Res 259:251-261.
21. Long WP, Pray-Grant M, Tsai JC and Perdew GH (1998) Protein kinase C activity is required for aryl hydrocarbon receptor pathway-mediated signal transduction. Mol Pharmacol 53:691-700.
22. Moore M, Wang X, Lu YF, Wormke M, Craig A, Gerlach JH, Burghardt R, Barhoumi R and Safe S (1994) Benzo[a]pyrene-resistant MCF-7 human breast cancer cells: A unique aryl hydrocarbon-nonresponsive clone. J Biol Chem 269:11751-11759.
23. Petruzzelli S, Celi A, Pulera N, Baliva F, Viegi G, Carrozzi L, Ciacchini G, Bottai M, Di Pede F, Paoletti P and Giuntini C (1998) Serum antibodies to benzo(a)pyrene diol epoxide-DNA adducts in the general population: Effects of air pollution, tobacco smoking, and family history of lung diseases. Cancer Res 58:4122-4126.
24. Phillips DH (1983) Fifty years of benzo(a)pyrene. Nature (Lond) 303:468-472.
25. Polzer RJ, Coffing SL, Marcus CB, Park SS, Gelboin HV and Baird WM (1995) Inhibition of benzo[a]pyrene metabolism by insulin, FITC-insulin and an FITC-insulin-antibody conjugate in the human hepatoma cell line HepG2. Chem Biol Interact 97:307-318.
26. Puisieux A, Lim S, Groopman J and Ozturk M (1991) Selective targeting of p53 gene mutational hotspots in human cancers by etiologically defined carcinogens. Cancer Res 51:6185-6189.
27. Raha A, Reddy V, Houser W and Bresnick EJ (1990) Binding characteristics of 4S PAH-binding protein and Ah receptor from rats and mice. Toxicol Environ Health 29:339-355.
28. Rosenthal N (1987) Identification of regulatory elements of cloned genes with functional assays. Methods Enzymol 152:704.
29. Rowlands JC and Gustafsson JA (1997) Aryl hydrocarbon receptor-mediated signal transduction. J Crit Rev Toxicol 27:109-134.
30. Santostefano M, Merchant M, Arellano L, Morrison V, Denison MS and Safe S (1993) α-Naphthoflavone-induced CYP1A1 gene expression and cytosolic aryl hydrocarbon receptor transformation. Mol Pharmacol 43:200-206.
31. Singh SV, Benson PJ, Hu X, Pal A, Xia H, Srivastava SK, Awasthi S, Zaren HA, Orchard JL and Awasthi YC (1998) Gender-related differences in susceptibility of A/J mouse to benzo[a]pyrene-induced pulmonary and forestomach tumorigenesis. Cancer Lett 128:197-204.
32. Sogawa K, Fujisawa-Sehara A, Yamane M and Fujii-Kuriyama Y (1986) Location of regulatory elements responsible for drug induction in the rat cytochrome P-450c gene. Proc Natl Acad Sci USA 83:8044-8048.
33. Soleas GJ, Diamandis, EP and Goldberg DM (1997) Wine as a biological fluid: History, production, and role in disease prevention. J Clin Lab Anal 11:287-313.
34. Steinmetz KA and Potter JD (1996) Vegetables, fruit, and cancer prevention: A review. J Am Diet Assoc 96:1027-39.
35. Szeliga J and Dipple A (1998) DNA adduct formation by polycyclic aromatic hydrocarbon dihydrodiol epoxides. Chem Res Toxicol 11:1-11.
36. Wattenberg LW (1996) Inhibition of tumorigenesis in animals. IARC Sci Publ 139: 151-158.
37. Xia H, Pan SS, Hu X, Srivastava SK, Pal A and Singh SV (1998) Cloning, expression, and biochemical characterization of a functionally novel alpha class glutathione S-transferase with exceptional activity in the glutathione conjugation of (+)-anti-7,8-dihydroxy-9,10-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene. Arch Biochem Biophys 353:337-348.