Role of CYP1A1 in modulation of antitumor properties of the novel agent 2-(4-amino-3-methylphenyl)benzothiazole (DF 203, NSC 674495) in human breast cancer cells

Cancer Research

Volumn 60, Issue 18, 2000, Pages 5196-5203

  Chua, M S ^a   Kashiyama, E ^a   Bradshaw, T D ^a   Stinson, S F ^a   Brantley, E ^a   Sausville, E A ^a   Stevens, M F G ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 (3 METHYL 4 AMINOPHENYL)BENZOTHIAZOLE; 2 (4 AMINO 3 METHYLPHENYL)BENZOTHIAZOLE; ANTINEOPLASTIC AGENT; CJM 126; CYTOCHROME P450 1B1; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; CYTOCHROME P450 ISOENZYME; DEBRISOQUINE 4 HYDROXYLASE; DF 203; ETHOXYRESORUFIN DEETHYLASE; IH 224; NSC 34445; NSC 703785; NSC 705627; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MICROSOME; PRIORITY JOURNAL;

ANILINE COMPOUNDS; ANTINEOPLASTIC AGENTS; BENZOFLAVONES; BREAST NEOPLASMS; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 ENZYME SYSTEM; DRUG INTERACTIONS; ENZYME INHIBITORS; HUMAN; HYDROXYLATION; ISOENZYMES; MIXED FUNCTION OXYGENASES; PROTEIN BINDING; SUBSTRATE SPECIFICITY; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; THIAZOLES; TUMOR CELLS, CULTURED;

EID: 0034665390     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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