The effect of bergamottin on diazepam plasma levels and P450 enzymes in beagle dogs

Drug Metabolism and Disposition

Volumn 30, Issue 2, 2002, Pages 135-140

  Sahi, Jasminder ^a   Reyner, Eric L ^a   Bauman, Jonathan N ^a   Gueneva Boucheva, Kristina ^a   Burleigh, James E ^a   Thomas, V Hayden ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BERGAMOTTIN; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2B11; CYTOCHROME P450 3A12; DIAZEPAM; FUROCOUMARIN DERIVATIVE; OXYGENASE; PLACEBO; TOLBUTAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DOG; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG EFFECT; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INDUCTION; ENZYME INHIBITION; GRAPEFRUIT JUICE; HYDROXYLATION; JEJUNUM; LIQUID CHROMATOGRAPHY; LIVER MICROSOME; MALE; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; ANIMALS; ANTI-ANXIETY AGENTS; BEVERAGES; CITRUS; CYTOCHROME P-450 ENZYME SYSTEM; DIAZEPAM; DOGS; DRUG INTERACTIONS; INJECTIONS, INTRAVENOUS; INTESTINAL MUCOSA; LIVER; MALE; PLANT COMPONENTS; PSORALENS;

ANIMALIA; CANIS FAMILIARIS; CITRUS X PARADISI;

EID: 0036146639     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.30.2.135     Document Type: Article

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