Consequences of calcium interactions with phytate and phytase for poultry and pigs

Livestock Science

Volumn 124, Issue 1-3, 2009, Pages 126-141

  Selle, Peter H ^a   Cowieson, Aaron J ^b   Ravindran, V ^c  

^a UNIVERSITY OF SYDNEY   (Australia)

^b AB VISTA   (United Kingdom)

^c MASSEY UNIVERSITY   (New Zealand)

Author keywords

Calcium; Phosphorus; Phytase; Phytate; Pigs; Poultry

Indexed keywords

SUIDAE;

EID: 67349266576     PISSN: 18711413     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.livsci.2009.01.006     Document Type: Article

References (205)

1. Abelson P.H. A potential phosphorus crisis. Science 283 (1999) 2015
2. Abugassa S., and Svensson O. Rickets induced by calcium or phosphate depletion. Int. J. Expt. Path. 71 (1990) 631-638
3. Adeola O., and Sands J.S. Does supplementary microbial phytase improve amino acid utilization? A perspective that it does not. J. Anim. Sci. 81 E. Suppl. 2 (2003) E78-E85
4. Adeola O., Olukosi O.A., Jendza J.A., Dilger R.N., and Bedford M.R. Response of growing pigs to Peniophora lycii- and Escherichia coli-derived phytases or varying ratios of calcium to total phosphorus. Anim. Sci. 82 (2006) 637-644
5. Aksakal D.H., and Bilal T. Effects of microbial phytase and 1,25-dihydroxycholecalciferol on the absorption of minerals from broiler chicken diets containing different levels of calcium. Acta Vet. Hung. 50 (2002) 307-313
6. Allen A., and Flemstrom G. Gastroduodenal mucus bicarbonate barrier: protection against acid and pepsin. Amer. J. Physiol. (Cell Physiol.) 288 (2005) C1-C19
7. Anderson R.J. The hydrolysis of phytin by the enzyme phytase contained in wheat bran. J. Biol. Chem. 20 (1915) 475-482
8. Anderson P.A. Interactions between proteins and constituents that affect protein quality. In: Finley J.W., and Hopkins D.T. (Eds). Digestibility and Amino Acid Availability in Cereals and Oilseeds (1985), American Association of Cereal Chemists, St. Paul, Minnesota 31-45
9. Angel R., Tamin N.M., Applegate T.J., Dhandu A.S., and Ellestad L.E. Phytic acid chemistry: influence on phytin-phosphorus availability and phytase efficacy. J. Appl. Poult. Res. 11 (2002) 471-480
10. Applegate T.J., Angel R., and Classen H.L. Effect of dietary calcium, 25-hydroxycholecalciferol, or bird strain on small intestinal phytase activity in broiler chickens. Poult. Sci. 82 (2003) 1140-1148
11. Appurao A.G., and Narasinga Rao M.S. Binding of Ca(II) by the 11S fraction of soybean proteins. Cereal Chem. 52 (1975) 21-33
12. Augspurger N.R., and Baker D.H. Phytase improves dietary calcium utilization in chicks, and oyster shell, carbonate, citrate, and citrate-malate forms of calcium are equally bioavailable. Nutr. Res. 24 (2004) 293-301
13. Ballam G.C., Nelson T.S., and Kirby L.K. Effect of different levels of calcium and phosphorus on phytate hydrolysis by chicks. Nutr. Reports Int. 32 (1985) 909-913
14. Beaulieu A.D., Bedford M.R., and Patience J.F. Supplementing corn or corn-barley diets with an E. coli derived phytase decreases total and soluble P output by weanling and growing pigs. Can. J. Anim. Sci. 87 (2007) 353-364
15. Bedford M.R. New enzyme technologies for poultry feeds. Brit. Poult. Sci. 44 Suppl. (2003) S14-S16
16. Bedford M.R., Murphy C., and Persia M.E. A holo-anlaysis of trials investigating the gain and feed conversion benefits of Quantum™ phytase supplementation to broilers under a variety of managerial, environmental and dietary conditions. Poult. Sci. 86 Suppl. 1 (2007) 673 (Abstr.)
17. Bedford M.R., Parr T., Persia M.E., Batal A., and Wyatt C.L. Influence of dietary calcium and phytase on litter moisture and mineral content. Poult. Sci. 86 Suppl. 1 (2007) 673 (Abstr.)
18. Bhaskaram C., and Reddy V. Role of dietary phytate in the aetiology of nutritional rickets. Indian J. Med. Res. 69 (1979) 265-270
19. Blumenfeld O.A., and Perlmann G.E. The amino acid composition of crystalline pepsin. J. Gen. Physiol. 42 (1958) 553-561
20. Brady S.M., Callan J.J., Cowan D., McGrane M., and O'Doherty J.V. Effect of phytase inclusion and calcium/phosphorus ratio on the performance and nutrient retention of grower-finisher pigs fed barley/wheat/soya bean meal-based diets. J. Sci. Food Agric. 82 (2002) 1780-1790
21. Bruce H.M., and Callow R.K. Cereals and rickets. The role of inositol hexaphosphoric acid. Biochem. J. 28 (1934) 517-528
22. Bunzen S., Rostagno H.S., Albino L.F.T., Nery L.R., and Silva C.R. Calcium and available phosphorus levels at 2:1 ratio for growing broiler chickens. Poult. Sci. 86 Suppl. 1 (2007) 73 (Abstr.)
23. Camden B.J., Morel P.C.H., Thomas D.V., Ravindran V., and Bedford M.R. Effectiveness of exogenous microbial phytase in improving the bioavailabilities of phosphorus and other nutrients in maize-soya-bean meal diets for broilers. Anim. Sci. 73 (2001) 289-297
24. Campbell G.L., and Bedford M.R. Enzyme applications for monogastric feeds: a review. Can. J. Anim. Sci. 72 (1992) 449-466
25. Camus M.C., and Laporte J.C. Inhibition de la protéolyse pesique par le blé. Rôle de l'acide phytique des issues. Annal. Biol. Anim. Biochim. Biophys. 16 (1976) 719-729
26. Centeno C., Arija I., Viveros A., and Brenes A. Effects of citric acid and microbial phytase on amino acid digestibility in broiler chickens. Brit. Poult. Sci. 48 (2007) 469-479
27. Champagne E.T. Effects of Ca(II) ions on Cu(II) ion-phytic acid interactions. J. Inorg. Biochem. 31 (1987) 29-42
28. Champagne E.T. Effects of pH on mineral-phytate, protein-mineral-phytate and mineral-fiber interactions. Possible consequences of atrophic gastritis on mineral bioavailability from high fiber foods. J. Amer. Coll. Nutr. 7 (1988) 499-508
29. Champagne E.T., Fisher M.S., and Hinojosa O. NMR and ESR studies of interactions among divalent cations, phytic acid, and N-acetyl-amino acids. J. Inorg. Biochem. 38 (1990) 199-215
30. Cheryan M., Anderson F.W., and Grynspan F. Magnesiun-phytate complexes: effect of pH and molar ratio on solubility characteristics. Cereal Chem. 60 (1983) 235-237
31. Correll D.L. The role of phosphorus in the eutrophication of receiving waters: a review. J. Environ. Qual. 27 (1998) 261-266
32. Correll D.L. Phosphorus: a rate limiting nutrient in surface waters. Poult. Sci. 78 (1999) 674-682
33. Cosgrove D.J. The chemistry and biochemistry of inositol polyphosphates. Rev. Pure Appl. Chem. 16 (1966) 209-224
34. Cowieson A.J., and Ravindran V. Effect of phytic acid and microbial phytase on the flow and amino acid composition of endogenous protein at the terminal ileum of growing broiler chickens. Brit. J. Nutr. 98 (2007) 745-752
35. Cowieson A.J., and Ravindran V. Energetic implications of endogenous amino acid flow at the terminal ileum of broilers as influenced by phytate and phytase. Poult. Sci. 86 Suppl. 1 (2007) 674 (Abstr.)
36. Cowieson A.J., Acamovic T., and Bedford M.R. The effects of phytase and phytic acid on the loss of endogenous amino acids and minerals from broiler chickens. Brit. Poult. Sci. 45 (2004) 101-108
37. Cowieson, A.J., Ravindran, V., Selle, P.H., 2008. Influence of dietary phytic acid and source of microbial phytase on ileal endogenous amino acid flows in broiler chickens. Poult. Sci. 87, 2287-2299.
38. Debicki-Garnier A.M., and Hruby M. The effect of phytase and betaine on broiler performance and excreta characteristics. Proc. 14th Eur. Symp. Poult. Nutr. (2003), World's Poult. Sci. Assoc, Lillehammer, Norway 14-15
39. Desphande S.S., and Cheryan M. Effects of phytic acid divalent cations and their interactions on α-amylase activity. J. Food Sci. 49 (1984) 516-519
40. Driver J.P., Pesti G.M., Bakalli R.I., and Edwards H.M. Effects of calcium and nonphytate phosphorus concentrations on phytase efficacy in broiler chicks. Poult. Sci. 84 (2005) 1406-1417
41. Driver J.P., Pesti G.M., Bakalli R.I., and Edwards H.M. Calcium requirements of the modern broiler chicken as influenced by dietary protein and age. Poult. Sci. 84 (2005) 1629-1639
42. Dunn B.M., Deyrup C., Moesching W.G., Gilbert W.A., Nolan R.J., and Trach M.L. Inhibition of pepsin by zymogen activation fragments. J. Biol. Chem. 253 (1978) 7269-7275
43. Dykes C.W., and Kay J. The effect of modification of lysine and histidine residues on the potential activity of pig pepsinogen. Biochem. Soc. Trans. 5 (1977) 1535-1537
44. Engelen A.J., van der Heeft F.C., Randsdorp P.H.G., and Smit E.L.C. Simple and rapid determination of phytase activity. J. AOAC Int. 77 (1994) 760-764
45. Evans W.J., and Pierce A.G. Calcium-phytate complex formation studies. J. Amer. Oil Chem. Soc. 58 (1981) 850-851
46. Evans W.J., and Pierce A.G. Interaction of phytic acid with the metal ions, copper (II), cobalt (II). iron (III), magnesium (II), and manganese (II). J. Food Sci. 47 (1982) 1014-1015
47. Evans W.J., Marini M.A., and Martin C.J. Heat of precipitation of calcium phytate. J. Inorg. Biochem. 19 (1983) 129-132
48. Farkvam D.O., Nelson T.S., Kirby L.K., Johnson Z.B., and Stamps A.T. Calcium and phytic acid in chick nutrition. Nutr. Reports Int. 40 (1989) 33-42
49. Favus M.J. Factors that influence absorption and secretion of calcium in the small intestine and colon. Amer. J. Physiol. (Gastro. Liver Physiol. 11) 248 (1985) G147-G157
50. 2+ on beta-propellor phytases. Protein Pept. Letts. 15 (2008) 39-42
51. Gifford S.R., and Clydesdale F.M. Interactions among calcium, zinc and phytate with three protein sources. J. Food Sci. 55 (1990) 1720-1724
52. 32 by chicks and poults. J. Nutr. 62 (1957) 13-26
53. Glynn I.M. All hands to the sodium pump. J. Physiol. 462 (1993) 1-30
54. Godoy S., Chicco C., Meschy F., and Requena F. Phytic phosphorus and phytase activity of animal feed ingredients. Interciencia 30 (2005) 24-28
55. Gosselin R.E., and Coghlan E.R. The stability of complexes between calcium and orthophosphate, polymeric phosphate and phytate. Arch. Biochem. Biophys. 45 (1953) 301-311
56. Graf E. Calcium binding to phytic acid. J. Agric. Food Chem. 31 (1983) 851-855
57. Greiner R., Konietzny U., and Jany Kl.-D. Purification and characterization of two phytases from Escherichia coli. Arch. Biochem. Biophys. 303 (1993) 107-113
58. Greiner R., Lim B.L., Cheng C., and Carlsson N.-G. Pathway of phytate dephosphorylation by β-propeller phytases of different origins. Can. J. Microbiol. 53 (2007) 488-495
59. Grynspan F., and Cheryan M. Calcium phyate: effect of pH and molar ratio on in vitro solubility. J. Amer. Oil Chem. Soc. 60 (1983) 1761-1764
60. Guggenbuhl P., Pinon Quintana A., and Simoes Nunes C. Comparative effects of three phytases on phosphorus and calcium digestibility in the growing pig. Livestock Sci. 109 (2007) 258-260
61. Harms R.H., Waldroup P.W., Shirley R.L., and Ammerman C.B. Availability of phytic acid phosphorus for chick. Poult. Sci. 41 (1962) 1189-1991
62. Hartig T. Uber das Klebermehl. Botanische Zeitung 13 (1855) 881-885
63. Heaney R.P., and Nordin B.E.C. Calcium effects on phosphorus absorption: implications for the prevention and co-therapy of osteoporosis. J. Amer. Coll. Nutr. 21 (2002) 239-244
64. Heubner W., and Stadler H. Uber eine Titration-methode zur Bestimmung des Phytins. Biochem. Zeitschrift 64 (1914) 432-437
65. Hill R., and Tyler C. The influence of time, temperature, pH and calcium carbonate on the activity of the phytase of certain cereals. J. Agric. Sci. 44 (1954) 306-310
66. Hill R., and Tyler C. The reaction between protein and phytate. J. Agric. Sci. 44 (1954) 324-326
67. Holt L.E., La Mer V.K., and Chown H.B. Studies in calcification. I. The solubility of secondary and tertiary calcium phosphate under various conditions. J. Biol. Chem. 64 (1925) 509-565
68. Hoopaw P.D., and Goodman B.L. The influence of intermittent light on growth performance and other traits in young chicks. Poult. Sci. 55 (1976) 2285-2289
69. Hu H.L., Wise A., and Henderson C. Hydrolysis of phytate and inositol tri-, tetra-, and penta-phosphates by the intestinal mucosa of the pig. Nutr. Res. 16 (1996) 781-787
70. Hurwitz S., and Bar A. Calcium and phosphorus interrelationships in the intestine of the fowl. J. Nutr. 101 (1971) 677-686
71. Igbasan F.A., Manner K., Miksch G., Borriss R., Farouk A., and Simon O. Comparative studies of the in vitro properties of phytases from various microbial origins. Arch. Anim. Nutr. 53 (2000) 353-373
72. Igbasan F.A., Simon O., Miksch G., and Manner K. The effectiveness of an Escherichia coli phytase in improving phosphorus and calcium bioavailabilitites in poultry and young pigs. Arch. Anim. Nutr 54 (2001) 117-126
73. Jongbloed A.W., and Kemme P.A. Effect of pelleting mixed feeds on phytase activity and the apparent absorbability of phosphorus and calcium in pigs. Anim. Feed Sci. Technol. 28 (1990) 233-242
74. Jongbloed A.W., Mroz Z., and Kemme P.A. The effect of supplementary Aspergillus niger phytase in diets for pigs on concentration and apparent digestibility of dry matter, total phosphorus, and phytic acid in different sections of the alimentary tract. J. Anim. Sci. 70 (1992) 59-1168
75. Jongbloed A.W., van Diepen J.Th.M., Kemme P.A., and Broz J. Efficacy of microbial phytase on mineral digestibility in diets for gestating and lactating sows. Lives. Prod. Sci. 91 (2004) 143-155
76. Kasim A.B., and Edwards H.M. The analysis for inositol phosphate forms in feed ingredients. J. Sci. Food Agric. 76 (1998) 1-9
77. Kasim A.B., and Edwards H.M. Effect of sources of maize and maize particle size on the utilization of phytate phosphorus in broiler chickens. Anim. Feed Sci. Technol. 86 (2000) 15-26
78. Kaufman H.W., and Kleinberg I. Effect of pH on calcium binding by phytic acid and its inositol phosphoric acid derivatives and on the solubility of their calcium salts. Arch. Oral Biol. 16 (1971) 445-460
79. Kennefick S., and Cahman K.D. Inhibitory effect of wheat fibre extract on calcium absorption in Caco-2 cells: evidence for a role of associated phytate rather than fibre per se. Eur. J. Nutr. 39 (2000) 12-17
80. Kerr M.J., Classen H.L., and Newkirk R.W. The effects of gastrointestinal tract microflora and dietary phytase on inositol hexaphosphate hydrolysis in the chicken. Poult. Sci. 79 Suppl. 1 (2000) 11 (Abstr.)
81. Kies, A.K. 2005. Phytase studies in pigs and poultry. Effect on protein digestion and energy utilization. Doctoral thesis, Wageningen Institute of Animal Sciences, Wageningen University, The Netherlands.
82. Kies A.K., de Jonge L.H., Kemme P.A., and Jongbloed A.W. Interaction between protein, phyate, and microbial phytase. In vitro studies. J. Agric. Food Chem. 54 (2006) 1753-1758
83. Kies A.K., Kemme P.A., Sebek L.B.J., van Diepen J.Th.M., and Jongbloed A.W. Effect of graded doses and a high dose of microbial phytase on the digestibility of various minerals in weaner pigs. J. Anim. Sci. 84 (2006) 1169-1175
84. Kilburn J., and Edwards H.M. The response of broilers to the feeding of mash or pelleted diets containing maize of varying particle size. Brit. Poult. Sci. 42 (2001) 484-492
85. Kim J.C., Mullan B.P., Selle P.H., and Pluske J.R. Levels of total phosphorus, phytate-phosphorus and phytase activity in three varieties of West Australian wheats in response to growing region, growing season and storage. Aust. J. Agric. Res. 53 (2002) 1361-1366
86. Knuckles B.E., Kuzmicky D.D., and Betschart A.A. Effect of phytate and partially hydrolysed phytate on in vitro protein digestibility. J. Food Sci. 50 (1985) 1080-1082
87. Knuckles B.E., Kuzmicky D.D., Gumbmann M.R., and Betschart A.A. Effect of myo-inositol phosphate esters on in vitro and in vivo digestion of protein. J. Food Sci. 54 (1989) 1348-1350
88. Kornegay E.T., Radcliffe J.S., and Denbow D.M. Influence of Natuphos® phytase on calcium bioavailabilioy in plant ingredients and development of calcium equivalency values for swine and poultry. In: Coelho M.B., and Kornegay E.T. (Eds). Phytase in Animal Nutrition and Waste Management (1996), BASF Corporation, Mount Olive NJ 419-434
89. Kornegay E.T., Radcliffe J.S., and Zhang Z. Influence of phytase and diet composition on phosphorus and amino acid digestibilities, and phosphorus and nitrogen excretion in swine. BASF Technical Symposium preceding Carolina Swine Nutrition Conference (1998), BASF Corporation, Mount Olive NJ 125-155
90. Krieger C.H., Bunkfeldt R., and Steenbock H. Cereals and rickets XI. Calcium phytate as a source if calcium. J. Nutr. 20 (1940) 15-18
91. Kroll R.D. Effect of pH on the binding of calcium ions by soybean proteins. Cereal Chem. 61 (1984) 490-495
92. Lantzsch H.-J., Wjst S., and Drochner W. The effect of dietary calcium on the efficacy of microbial phytase in rations for growing pigs. J. Anim. Physiol. Anim. Nutr. 73 (1995) 19-26
93. Lawlor P.G., Lynch P.B., Caffrey P.J., O'Reilly J.J., and O'Connell M.K. Measurements of the acid-binding capacity of ingredients used in pig diets. Irish Vet. J. 58 (2005) 447-452
94. Leeson S. Recent advances in fat utilization by poultry. In: Farrell D.J. (Ed). Recent Advances in Animal Nutrition in Australia (1993), University of New England, Armidale, NSW 170-181
95. Lei X.G., and Stahl C.H. Nutritional benefits of phytase and dietary determinants of its efficacy. J. Appl. Anim. Res. 17 (2000) 97-112
96. Lei X.G., Ku P.K., Miller E.R., Yokoyama M.T., and Ullrey D.E. Calcium level affects the efficacy of supplemental microbial phytase in corn-soybean meal diets of weanling pigs. J. Anim. Sci. 72 (1994) 139-143
97. Leytem A.B., Plumstead P.W., Maguire R.O., Kwanyuen P., and Brake J. What aspect of dietary modification in broilers controls litter water-soluble phosphorus: dietary phosphorus, phytase or calcium?. J. Environ. Qual. 36 (2007) 453-463
98. Leytem A.B., Plumstead P.W., Maguire R.O., Spears J.W., Kwanyuen P., Burton J.W., and Brake J. Interaction of calcium and phytate in broiler diets. 2. Effects on total and soluble phosphorus excretion. Poult. Sci. 87 (2007) 459-467
99. Leytem A.B., Smith D.R., Applegate T.J., and Thacker P.A. The influence of manure phytic acid on phosphorus solubility in calcareous soils. Soil Sci. Soc. Am. J. 70 (2006) 1629-1638
100. Li D., Che X.R., Wang Y.Q., Qiao S.Y., Cao H., Johnson W., and Thacker P. The effect of calcium level on microbial phytase activity and nutrient balance in swine. Asian-Austral. J. Anim. Sci. 12 (1999) 197-202
101. Liebert F., Wecke C., and Schoner F.-J. Phytase activities in different gut contents of chickens as dependent on levels of phosphorus and phytase supplementations. In: Wenk C., and Boessinger M. (Eds). Proc. 1st Symp. Enzymes Anim. Nutr. (1993), Kartause Ittingen, Switzerland 202-205
102. Lien K.A., Sauer W.C., and Fenton M. Mucin output in ileal digesta of pigs fed a protein-free diet. Z. Ernähr.wiss. 36 (1997) 182-190
103. Lillford P.J., and Wright D.J. Influence of isoelectric precipitation on the solubility of soya bean proteins. J. Sci. Food Agric. 32 (1981) 315-327
104. Liu J., Bollinger D.W., Ledoux D.R., and Veum T.L. Lowering the dietary calcium to total phosphorus ratio increases phosphorus utilization in low-phosphorus corn-soybean meal diets supplemented with microbial phytase for growing-finishing pigs. J. Anim. Sci. 76 (1998) 808-813
105. Liu J., Bollinger D.W., Ledoux D.R., and Veum T.L. Effects of dietary calcium:phosphorus ratios an apparent absorption of calcium and phosphorus in the small intestine, cecum, and colon of pigs. J. Anim. Sci 78 (2000) 106-109
106. Lonnerdal B., Sandberg A.-S., Sandstrom B., and Kunz C. Inhibitory effects of phytic acid and other inositol phosphates on zinc and calcium absorption in suckling rats. J. Nutr. 119 (1989) 211-214
107. Lott J.N.A., Ockenden I., Raboy V., and Batten G.D. Phytic acid and phosphorus in crop seed and fruits: a global estimate. Seed Sci. Res. 10 (2000) 11-33
108. Luttrell B.M. The biological relevance of the binding of calcium ions by inositol phosphates. J. Biol. Chem. 268 (1993) 1521-1524
109. Maddaiah V.T., Kurnick A.A., and Reid B.L. Phytic acid studies. Proc. Soc. Expt. Biol. Med. 115 (1964) 391-393
110. Maenz D.D., and Classen H.L. Phytase activity in the small intestinal brush border membrane of the chicken. Poult. Sci. 77 (1998) 557-563
111. Mahajan A., and Dua S. Nonchemical approach for reducing antinutritional factors in rapeseed (Brassica campestris Var. Toria) and characterization of enzyme phytase. J. Agric. Food Chem. 45 (1997) 2504-2508
112. Manangi M.K., and Coon C.N. The effect of calcium carbonate particle size and solubility on the utilization of phosphorus from phytase for broilers. Int. J. Poult. Sci. 6 (2007) 85-90
113. Marini M.A., Evans W.J., and Morris N.M. Calorimetric and potentiometric studies on the binding of calcium by phytic acid. J. Appl. Biochem. 7 (1985) 180-191
114. Martin C.J., and Evans W.J. Phytic acid-metal ion interactions. II. The effect of pH on Ca(II) binding. J. Inorg. Chem. 27 (1986) 17-30
115. Martinez-Amezcua C., Parsons C.M., and Baker D.H. Effect of microbial phytase on phosphorus bioavailability, apparent metabolizable energy, and amino acid digestibility in distillers dried grains with solubles in chicks. Poult. Sci. 85 (2006) 470-475
116. McCance R.A., and Widdowson E.M. Mineral metabolism on dephytinised bread. J. Physiol. 101 (1942) 304-313
117. McDonald M.W., and Solvyns A. Dietary calcium levels and chicken growth. Proc. Aust. Poult. Sci. Conv. (1964), W.P.S.A. 112-116 (Australian Branch)
118. Mellanby A. The rickets-producing and anti-calcifying action of phytate. J. Physiol. 109 (1949) 488-533
119. Miles D.M., Moore P.A., Smith D.R., Rice D.W., Stilborn H.L., Rowe D.R., Lott B.D., Branton S.L., and Simmons J.D. Total and water-soluble phosphorus in broiler litter over three flocks with alum litter treatment and dietary inclusion of high available phosphorus corn and phytase supplementation. Poult. Sci. 82 (2003) 1544-1549
120. Mitchell R.D., and Edwards H.M. Effects of phytase and 1,25-dihydroxycholecalciferol on phytate utilization and the quantitative requirement for calcium and phosphorus in young broiler chickens. Poult. Sci. 75 (1996) 95-110
121. Mroz Z., Jongbloed A.W., and Kemme P. Intraduodenal infusion of microbial phytase to evaluate its effect on the concentration and apparent digestibility of phosphorus posterior to the stomach of pigs (1992), Research Institute for Livestock Feeding and Nutrition, Leystad, The Netherlands IVVO-DLO Report No 356.2002
122. Mroz Z., Jongbloed A.W., and Kemme P. Apparent digestibility and retention of nutrients bound to phytate complexes as influenced by microbial phytase and feeding regimen in pigs. J. Anim. Sci. 72 (1994) 126-132
123. Mullaney E.J., Daly C.B., and Ullah A.H.J. Advances in phytase research. Adv. Appl. Microbiol. 47 (2000) 157-199
124. Murai A., Kita K., Tsuruta S., and Okumura J. Interaction of dietary phytase and glutamic acid on bone ash response in chicken thigh. Jap. Poult. Sci. 38 (2001) 146-151
125. Murukami A.E., Saleh E.A., England J.A., Dickey D.A., Watkins S.E., and Waldroup P.W. Effect of level and source of sodium on performance of male broilers to 56 days. J. Appl. Poult. Sci. 6 (1997) 128-136
126. Nash K.L., Jensen M.P., and Schmidt M.A. Actinide immobilization in the subsurface environment by in-situ treatment with a hydrolytically unstable organophosphorous complexant: uranyl uptake by calcium phytate. J. Alloys Comp. 271-273 (1998) 257-261
127. National Research Council. Nutrient requirements for domestic animals. Nutrient Requirements for Poultry (1994), National Academy Press, Washington, DC (9th revised edition)
128. Nelson T.S. The utilization of phytate phosphorus by the chick-a review. Poult. Sci. 46 (1967) 862-871
129. Nelson T.S. Available calcium for poultry. Proc. Florida Nutr. Conf. Feed Manuf. Pp. 1-7. Orlando, Florida (1984)
130. Nelson T.S., and Kirby L.K. The calcium binding properties of natural phytate in chick diets. Nutr. Reports Int. 35 (1987) 949-956
131. Nyachoti C.M., de Lange C.F.M., McBride B.W., Leeson S., and Gabert V.M. Endogenous gut nitrogen losses in growing pigs are not caused by increased protein synthesis rates in the small intestine. J. Nutr. 130 (2000) 566-572
132. Oberleas D., and Chan H.C. Cation complexation by phytate. Trace Elem. Electrolytes 14 (1997) 173-176
133. Officer D.I., and Batterham E.S. Enzyme supplementation of Linola™ meal for grower pigs. In: Foot J.Z. (Ed). Proc. Aust. Soc. Anim. Prod. vol. 19 (1992), Latrobe University, Vic 288
134. Officer D.I., and Batterham E.S. Enzyme supplementation of Linola™ meal. Fourth Biennial Pig Industry Seminar (1992), Wollongbar Agricultural Institute, Wollongbar, NSW 56
135. 2+ on phytate binding to glycinin. Cereal Sci. Today 19 (1974) 401 (Abstr.)
136. Okubo K., Myers D.V., and Iacobucci G.A. Binding of phytic acid to glycinin. Cereal Sci. Today 19 (1974) 401 (Abstr.)
137. Okubo K., Myers D.V., and Iacobucci G.A. Binding of phytic acid to glycinin. Cereal Chem. 53 (1976) 513-524
138. Okubo K., Waldrop A.B., Iacobucci G.A., and Myers D.V. Preparation of low-phytate soybean protein isolate and concentrate by ultrafiltration. Cereal Chem. 52 (1975) 263-271
139. Olukosi O.A., Cowieson A.J., and Adeola O. Energy utilization and growth performance of broilers receiving diets supplemented with enzymes containing carbohydrase or phytase activity individually or in combination. Brit. J. Nutr. 99 (2008) 682-690
140. Onyango E.M., Bedford M.R., and Adeola O. Efficacy of an evolved Escherichia coli phytase in diets for broiler chicks. Poult. Sci. 84 (2005) 248-255
141. O'Quinn P.R., Knabe D.A., and Gregg E.J. Efficacy of Natuphos® in sorghum-based diets of finishing swine. J. Anim. Sci. 75 (1997) 1299-1307
142. Pagano A.R., Roneker K.R., and Lei X.G. Distribution of supplemental Escherichia coli AppA2 phytase activity in digesta of various gastrointestinal segments of young pigs. J. Anim. Sci. 85 (2007) 1444-1452
143. Pallauf J., Rimbach G., Pippig B., Schindler B., and Most E. Effect of phytase supplementation to a phytate-rich diet based on wheat, barley and soya on the bioavailability of dietary phosphorus, calcium, magnesium, zinc and protein in piglets. Agribiol. Res. 47 (1994) 39-48
144. Pang Y., and Applegate T.J. Effects of dietary copper supplementation and copper source on digesta pH, calcium, zinc, and copper complex size in the gastrointestinal tract of broiler chickens. Poult. Sci. 86 (2007) 531-537
145. Patwardhan V.N. The occurrence of a phytin-splitting enzyme in the intestines of albino rats. Biochem. J. 31 (1937) 560-564
146. Pfeffer W. Untersuchungen uber die Proteinkorner und die Bedeutung des Asparagins bei Kiemen der Samen. Jahrbuch Wissenschaftlicher Botanik 8 (1872) 429-437
147. Plimmer R.H.A. IV. The metabolism of organic phosphorus compounds. Their hydrolysis by the action of enzymes. Biochem. J. 7 (1913) 43-71
148. Plumstead P.W., Leytem A.B., Maguire R.O., Spears J.W., Kwanyuen P., and Brake J. Interaction of calcium and phytate in broiler diets. 1. Effects on apparent prececal digestibility and retention of phosphorus. Poult. Sci. 87 (2007) 449-458
149. Pontoppidan K., Pettersson D., and Sandberg A.-S. Interaction of phytate with protein and minerals in a soybean-maize meal blend depends on pH and calcium addition. J. Sci. Food Agric. 87 (2007) 1886-1892
150. Pos J., Enting H., and Veldman A. Effect of phytase and dietary calcium level on litter quality and broiler performance. Proc. 14th Eur. Symp. Poult. Nutr. (2003), World's Poultry Science Association, Lillehammer, Norway 17-18
151. Prattley C.A., Stanley D.W., and van der Voort F.R. Protein-phytate interactions in soybeans. II. Mechanism of protein-phytate binding as affected by calcium. J Food Biochem. 6 (1982) 255-271
152. Qian H., Gregory E.M., and Kornegay E.T. Characterization if Aspergillus niger phytase and investigation of the inhibitory effect of cations on the phytase activity. J. Anim. Sci. 74 Suppl. 1 (1996) 8 (Abstr.)
153. Qian H., Kornegay E.T., and Conner D.E. Adverse effects of wide calcium:phosphorus ratios on supplemental phytase efficacy for weanling pigs fed two dietary phosphorus levels. J. Anim. Sci. 74 (1996) 1288-1297
154. Qian H., Kornegay E.T., and Denbow D.M. Phosphorus equivalence of microbial phytase in turkey diets as influenced by calcium to phosphorus ratios and phosphorus levels. Poult. Sci. 75 (1996) 69-81
155. Qian H., Kornegay E.T., and Denbow D.M. Utilization of phytate phosphorus and calcium as influenced by microbial phytase, cholecalciferol, and the calcium:total phosphorus ratio in broiler diets. Poult. Sci. 76 (1997) 37-46
156. Radcliffe J.S., Pleasant R.S., and Kornegay E.T. Estimating equivalency values of microbial phytase for amino acids in growing and finishing pigs fitted with steered ileo-caecal valve cannulas. J. Anim. Sci. 84 (2006) 1119-1129
157. Rajendran S., and Prakash V. Kinetics and thermodynamics of the mechanism of interaction of sodium phytate with α-globulin. Biochemistry 32 (1993) 3474-3478
158. Ravindran V., Cabahug S., Ravindran G., Selle P.H., and Bryden W.L. Response of broiler chickens to microbial phytase supplementation as influenced by dietary phytic acid and non-phytate phosphorus levels. II. Effects on apparent metabolisable energy, nutrient digestibility and nutrient retention. Brit. Poult. Sci. 41 (2000) 193-200
159. Ravindran V., Cowieson A.J., and Selle P.H. Influence of dietary electrolyte balance and microbial phytase on growth performance, nutrient utilization and excreta quality of broiler chickens. Poult. Sci. 87 (2008) 677-688
160. Ravindran V., Morel P.C.H., Partridge G.G., Hruby M., and Sands J.S. Influence of an E. coli-derived phytase on nutrient utilization in broiler starters fed diets containing varying concentrations of phytic acid. Poultry Sci. 85 (2006) 82-89
161. Reddy N.R., and Salunkhe D.K. Interactions between phytate, protein, and minerals in whey fractions of black gram. J. Food Sci. 46 (1981) 564-570
162. Rickard S.E., and Thompson L.U. Interactions and biological effects of phytic acid. In: Shahidi F. (Ed). Antinutrients and Phytochemicals in Food (1997), American Chemical Society, Washington DC 294-312
163. Rojas S.W., and Scott M.L. Factors affecting the nutritive value of cottonseed meal as a protein source in chick diets. Poult. Sci. 48 (1969) 819-835
164. Sakakibara M., and Noguchi H. Interaction of 11S fraction of soybean protein with calcium ion. Agric. Biol. Chem. 41 (1977) 1575-1580
165. Sandberg A.-S., Larsen T., and Sandstrom B. High dietary calcium level decreases colonic phytate degradation in pigs fed a rapeseed diet. J. Nutr. 123 (1993) 559-566
166. Scheuermann S.E., Lantzsch H.-J., and Menke K.H. In vitro und in vivo Untersuchungen zur Hydrolyse von Phytat. II. Aktivität pflanzlicher Phytase. J. Anim. Physiol. Nutr. 60 (1988) 64-75
167. Schöner F.J., Schwarz G., Hoppe P.P., and Wiesche H. Effect of microbial phytase on Ca-availability in broilers. Tagung Schweine- und Geflügelernährung (1994), Universitat Halle, Germany
168. Sebastian S., Touchburn S.P., Chavez E.R., and Lague P.C. The effects of supplemental microbial phytase on the performance and utilization of dietary calcium, phosphorus, copper, and zinc in broiler chickens fed corn-soybean diets. Poult. Sci. 75 (1996) 729-736
169. Selle P.H., and Ravindran V. Microbial phytase in poultry nutrition. Anim. Feed Sci. Technol. 135 (2007) 1-41
170. Selle P.H., and Ravindran V. Phytate-degrading enzymes in pig nutrition. Livestock Sci. 113 (2008) 99-122
171. Selle P.H., Ravindran V., Bryden W.L., and Scott T. Influence of dietary phytate and exogenous phytase on amino acid digestibility in poultry: a review. J. Poult. Sci. 43 (2006) 89-103
172. Selle P.H., Ravindran V., Caldwell R.A., and Bryden W.L. Phytate and phytase: consequences for protein utilisation. Nutr. Res. Rev. 13 (2000) 255-278
173. Selle P.H., Ravindran V., Ravindran G., and Bryden W.L. Effects of dietary lysine and microbial phytase on growth performance and nutrient utilisation of broiler chickens. Asian-Austral. J. Anim. Sci. 20 (2007) 1100-1107
174. Selle P.H., Walker A.R., and Bryden W.L. Total and phytate-phosphorus contents and phytase activity of Australian-sourced feed ingredients for pigs and poultry. Aust. J. Expt. Agric. 45 (2003) 475-479
175. Shafey T.M. Effects of high dietary calcium and fat levels on the performance, intestinal pH, body composition and size and weight of organs in growing chickens. Asian-Austral. J. Anim. Sci. 12 (1999) 49-55
176. Shafey T.M., McDonald M.W., and Dingle J.G. Effects of dietary calcium and available phosphorus concentration on digesta pH and on the availability of calcium, iron, magnesium, and zinc from the intestinal contents of meat chickens. Brit. Poult. Sci. 32 (1991) 185-194
177. Sharma C.B., Goel M., and Irshad M. Myoinositol hexaphosphate as a potential inhibitor of α-amylases. Phytochemistry 17 (1978) 201-204
178. Sharpley A. Agricultural phosphorus, water quality and poultry production: are they compatible?. Poult. Sci. 78 (1999) 660-673
179. Sharpley A.N., Robinson J.S., and Smith S.J. Bioavailable phosphprus dynamics in agricultural soils and effects on water quality. Geoderma 67 (1995) 1-15
180. Shelton J.L., Southern L.L., Gaston L.A., and Foster A. Evaluation of nutrient matrix values for phytase in broilers. J. Appl. Poult. Res. 13 (2004) 213-221
181. Shin S., Ha N.-C., Oh B.-C., Oh T.-K., and Oh B.-H. Enzyme mechanism and catalytic property of β propeller phytase. Structure 9 (2001) 851-858
182. Shirley R.B., and Edwards H.M. Dietary calcium affects phytase activity when phytase is supplemented in excess of industry standards. Poult. Sci. 81 Suppl. 1 (2002) 11 (Abstr.)
183. Shirley R.B., and Edwards H.M. Graded levels of phytase past industry standards improves broiler performance. Poult. Sci. 82 (2003) 671-680
184. Simons P.C.M., Versteegh H.A.J., Jongbloed A.W., Kemme P.A., Slump P., Bos K.D., Wolters M.G.E., Beudeker R.F., and Verschoor G.J. Improvement of phosphorus availability by microbial phytase in broilers and pigs. Brit. J. Nutr. 64 (1990) 525-540
185. Sims J.T., Simard R.R., and Joern B.C. Phosphorus loss in agricultural drainage: historical perspective and current research. J. Environ. Qual. 27 (1998) 277-293
186. Singh J., and Sikka S.S. Effect of phytase supplementation at different Ca:tP ratios on the growth performance of broiler chicks. Indian J. Poult. Sci. 41 (2006) 159-164
187. Singh J., and Sikka S.S. Effect of phytase supplementation at different Ca:tP ratios on the utilisation of various nutrients in broiler chicks. Indian J. Poult. Sci. 41 (2006) 171-175
188. Suzucki U., Yoshimura K., and Takaishi M. Uber ein Enzym "Phytase" das Anhydro-oxy-methylen-diphosposaure spaltet. Coll. Agric. Bull. Tokyo Imp. Univ. 7 (1907) 503-505
189. Takemasa M., Murakami H., and Yamazaki M. Reduction of phosphorus excretion of chicks by addition of yeast phytase. Jap. Poult. Sci. 33 (1996) 104-111
190. Tamim N.M., and Angel R. Phytate phosphorus hydrolysis as influenced by dietary calcium and micro-mineral source in broiler diets. J. Agric. Food Chem. 51 (2003) 4687-4693
191. Tamim N.M., Angel R., and Christman M. Influence of dietary calcium and phytase on phytate phosphorus hydrolysis in broiler chickens. Poult. Sci. 83 (2004) 1358-1367
192. Tang J., Sepulveda P., Marciniszyn J., Chen K.C.S., Huang W.-Y., Tao N., Liu D., and Lanier J.P. Amino-acid sequence of porcine pepsin. Proc. Natl. Acad. Sci. 70 (1973) 3437-3439
193. Taylor T.G. The availability of the calcium and phosphorus of plant materials for animals. Proc. Nutr. Soc. 24 (1965) 105-112
194. Thompson L.U. Phytic acid: a factor influencing starch digestibility and blood glucose response. In: Graf E. (Ed). Phytic Acid: Chemistry and Applications (1988), Pilatus Press, Minneapolis 173-194
195. Thompson L.U., Button C.L., and Jenkins D.J.A. Phytic acid and calcium affect the in vitro rate of navy bean starch digestion and blood glucose response in humans. Amer. J. Clin. Nutr. 46 (1987) 467-473
196. Traylor S.L., Cromwell G.L., Lindemann M.D., and Knabe D.A. Effect of level of supplemental phytase on ileal digestibility of amino acids, calcium, and phosphorus in dehulled soyabean meal for grower pigs. J. Anim. Sci. 79 (2001) 2634-2642
197. Vaintraub I.A., and Bulmaga V.P. Effect of phytate on the in vitro activity of digestive proteinases. J. Agric. Food Chem. 39 (1991) 859-861
198. Van der Klis J.D., Versteegh H.A.J., Simons P.C.M., and Kies A.K. The efficacy of phytase in corn-soybean meal-based diets for laying hens. Poult. Sci. 76 (1997) 1535-1542
199. Vohra P., Gray G.A., and Kratzer F.H. Phytic acid-metal complexes. Proc. Soc. Expt. Biol. Med. 120 (1965) 447-449
200. Wasserman R.H. Calcium and phosphorus interactions in nutrition and physiology. Fed. Proc. 19 (1960) 636-642
201. Wise A., and Gilburt D.J. Binding of cadmium and lead to the calcium-phytate complex in vitro. Toxicol. Lett. 9 (1981) 45-50
202. Wise A. Dietary factors determining the biological activity of phytates. Nutr. Abstr. Rev. Clin. Nutr. 53 (1983) 791-806
203. Yan F., Kersey J.H., Fritts C.A., and Waldroup P.W. Effect of phytase supplementation on the calcium requirement of broiler chicks. Int. J. Poult. Sci. 5 (2006) 112-120
204. Yi Z., and Kornegay E.T. Sites of phytase activity in the gastrointestinal tract of young pigs. Anim. Feed Sci. Technol. 61 (1996) 361-368
205. Zyla K., Koreleski J., Swiatkiewicz S., Wikiera A., Kujawski M., Piironen J., and Ledoux D.R. Effects of phosphorolytic and cell wall degrading enzymes on the performance of growing broilers fed wheat-based diets containing different calcium levels. Poult. Sci. 79 (2000) 66-76