Nutritional benefits of phytase and dietary determinants of its efficacy

Journal of Applied Animal Research

Volumn 17, Issue 1, 2000, Pages 97-112

  Lei, X G ^a   Stahl, C H ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

Phosphorus; Phytase; Phytate; Pigs; Poultry

Indexed keywords

SUS SCROFA;

EID: 0002340986     PISSN: 09712119     EISSN: 09741844     Source Type: Journal    
DOI: 10.1080/09712119.2000.9706294     Document Type: Article

References (84)

1. Adeola, O. 1995. Digestive utilization of minerals by weanling pigs fed copper- and phytase-supplemented diets. Can. J. Anim. Sci., 75: 603-610.
2. Adeola, O., Lawrence, B.V., Sutton, A.L. and Cline, T.R. 1995. Phytase-induced changes in mineral utilization in zinc-supplemented diets for pigs. J. Anim. Sci., 73: 3384-3391.
3. Andersson, H., Navert, B., Bingham, S.A., Englyst, H.N. and Cummings, J.H. 1983. The effects of breads containing similar amounts of phytate but different amounts of wheat bran on calcium, zinc and iron balance in man. Brit. J. Nutr., 50: 503-510.
4. Berka, R.M., Rey, M.W., Brown, K.M., Byun, T. and Klotz, A.V. 1998. Molecular characterization and expression of a phytase gene from the thermophilic fungus Thermomyces lanuginosus. Appl. Environ. Microbiol., 64: 4423-4427.
5. Biehl, R.R. and Baker, D.H. 1996. Efficacy of supplemental la-hydroxycholecalciferol and microbial phytase for young pigs fed phosphorus- or amino acid- deficient corn-soybean meal diets. J. Anim. Sci., 74: 2960-2966.
6. Biehl, R.R. and Baker, D.H. 1997. Microbial phytase improves amino acid utilization in young chicks fed diets based on soybean meal but not diets based on peanut meal. Poult. Sci., 76: 355-360.
7. Biehl, R.R., Baker, D.H. and DeLuca, H.F. 1995. Lα-hydroxlated cholecalciferol compounds act additively with microbial phytase to improve phosphorus, zinc and manganese utilization in chicks fed soy-based diets. J. Nutr., 125: 2407-2416.
8. Bitar, K. and Reinhold, J.G. 1972. Phytase and alkaline phosphatase activities in intestinal mucosae of rat, chicken, calf and man. Biochim. Biophys. Acta, 268: 442-452.
9. Bobilya, D.J., Ellersieck, M.R., Gordon, D.T. and Veum, T.L. 1991. Bioavailabilities of zinc from nonfat dry milk, lowfat plain yogurt and soy flour in diets fed to neonatal pigs. J. Agric. Food Chem., 39: 1246-1251.
10. Brune, M., Rossander-Hultén, L., Hallberg, L., Gleerup, A. and Sandberg, A.S. 1992. Iron absorption from bread in humans: inhibiting effects of cereal fiber, phytate and inositol phosphates with different numbers of phosphate groups. J. Nutr., 122: 442-449.
11. Cooper, J.R. and Gowing, H.S. 1983. Mammalian small intestinal phytase. Brit. J. Nutr., 50: 673-678.
12. Cromwell, G.L. 1980. Biological availability of phosphorus in feedstuffs for swine. Feedstuffs, 52: 14-16.
13. Cromwell, G.L., Stahly, T.S., Coffey, R.D., Monegue, H.J. and Randolph, J.H. 1993. Efficacy of phytase in improving the bioavailability of phosphorus in soybean meal and corn-soybean meal diets for pigs. J. Anim. Sci., 71: 1831-1840.
14. Davies, N.T. and Flett, A.A. 1978. The similarity between alkaline phosphatase and phytase activities in rat intestine and their importance in phytate-induced zinc deficiency. Brit. J. Nutr., 39: 307-316.
15. Davies, N.T. and Olpin, S.E. 1979. Studies on the phytate : zinc molar contents in diets as a determinant of Zn availability to young rats. Brit. J. Nutr., 41: 591-603.
16. Denbow, D.M., Ravindran, V., Kornegay, E.T., Yi, Z. and Hulet, R.M. 1995. Improving phosphorus availability in soybean meal for broilers by supplemental phytase. Poult. Sci., 74: 1831-1842.
17. Easter, R.A. 1993. Acidification of diets/for pigs. In: Cole, D.J.A., Haresign, W., Garnsworthy, P.C. (Eds) Recent developments in pig nutrition 2. Nottingham University Press, Loughborough, England, 256-266.
18. Eeckhout, W. and De Paepe, M. 1994. Total phosphorus, phytate-phosphorus and phytase activity in plant feedstuffs. Anim. Feed Sci. Technol., 47: 19-29.
19. Giesting, D.W. and Easter, R.A. 1985. Response of starter pigs to supplementation of corn-soybean meal diets with organic acids. J. Anim. Sci., 60: 1288-1294.
20. Greiner, R., Kontietzny, U. and Jany, K.I.-D. 1993. Purification and characterization of two phytases from Escherichia coli. Arch. Biochem. Biophys., 303:107-113.
21. Hallberg, L., Brune, M. and Rossander, L. 1989. Iron absorption in man: ascorbic acid and dose-dependent inhibition by phytate. Am. J. Clin. Nutr., 49: 140-144.
22. Hallberg, L., Rossander, L. and Skanberg, A. 1987. Phytates and the inhibitory effect of bran on iron absorption in man. Am. J. Clin. Nutr., 45: 988-996.
23. Han, Y.M., Roneker, K.R., Pond, W.G. and Lei, X.G. 1998. Adding wheat middlings, microbial phytase and citric acid to corn-soybean meal diets for growing pigs may replace inorganic phosphorus supplementation. J. Anim. Sci., 76: 2649-2656.
24. Han, Y.M., Wilson, D.B. and Lei, X.G. 1999. Expression of an Aspergillus niger phytase gene (phyA) in Saccharomyces cerevisiae. Appl. Environ. Microbiol., 65: 1915-1918.
25. Han, Y.M., Yang, F., Zhou, A.G., Miller, E.R., Ku, P.K., Hogberg, M.G. and Lei, X.G. 1997. Supplemental phytases of microbial and cereal sources improve dietary phytate phosphorus utilization by pigs from weaning through finishing. J. Anim. Sci., 75: 1017-1025.
26. Han, Y.W. and Wilfred, A.G. 1988. Phytate hydrolysis in soybean and cottonseed meals by Aspergillus ficuum phytase. J. Agric. Food Chem., 36: 259-262.
27. Hohler, D. and Pallauf, J. 1993. Untersuchungen zum einfluss von zitronensaure auf die mineralstoffverwertung beim ferkel anhand einer mais-soja-diat mit und ohne Zn-erganzung. J. Anim. Physiol. Anim. Nutr., 69: 132-134.
28. Jongbloed, A.W., Kemme, P.A., Mroz, Z. and Jongbloed, R. 1996. The effects of organic acids in diets for growing pigs on the efficacy of microbial phytase. In: Coelho, M.B., Kornegay, E.T. (Eds.) Phytase in Animal Nutrition and Waste Management. BASF Co., Mt. Olive, NJ, pages 515-524.
29. Jongbloed, A.W., Mroz, Z. and Kemme, P.A. 1992. The effect of supplementary Aspergillus niger phytase in diets for pigs on concentration and apparent digestibility of dry matter, total phosphorus, and phytic acid in different sections of the alimentary tract. J. Anim. Sci., 70: 1159-1168.
30. Kemme, P.A., Jongbloed, A.W., Mroz, Z. and Beynen, A.C. 1997. The efficacy of Aspergillus niger phytase in rendering phytate phosphorus available for absorption in pigs is influenced by pig physiological status. J. Anim. Sci., 75: 2129-2138.
31. Kerovuo, J., Lauraeus, M., Nurminen, P., Kalkkinen, N. and Apajalahti, J. 1998. Isolation, characterization, molecular gene cloning and sequencing of a novel phytase from Bacillus subtilis. Appl. Environ. Microbiol., 64: 2079-2085.
32. Kornegay, E.T., Denbow, D.M., Yi, Z. and Ravindran, V. 1996. Response of broilers to graded levels of microbial phytase added to maize-soybean-meal-based diets containing three levels of non-phytate phosphorus. Brit. J. Nutr., 75: 839-852.
33. Kornegay, E.T. and Qian, H. 1996. Replacement of inorgdnic phosphorus by microbial phytase for young pigs fed on a maize-soybean-meal diet. Brit. J. Nutr., 76: 563-578.
34. Larsson, M., Minekus, M. and Havenaar, R. 1997. Estimation of the bioavailability of iron and phosphorus in cereals using a dynamic in vitro gastrointestinal model. J. Sci. Food Agric., 74: 99-106.
35. Lei, X.G., Ku, P.K., Miller, E.R. and Yokoyama, M.T. 1993a. Supplementing corn-soybean meal diets with microbial phytase maximizes phytate phosphorus utilization by weanling pigs. J. Anim. Sci., 71: 3368-3375.
36. Lei, X.G., Ku, P.K., Miller, E.R. and Yokoyama, M.T. 1993b. Supplementing corn-soybean meal diets with microbial phytase linearly improves phytate phosphorus utilization by weanling pigs. J. Anim. Sci., 71: 3359-3367.
37. Lei, X.G., Ku, P.K., Miller, E.R., Ullrey, D.E. and Yokoyama, M.T. 1993c. Supplemental microbial phytase improves bioavailability of dietary zinc to weanling pigs. J. Nutr., 123: 1117-1123.
38. Lei, X.G., Ku, P.K., Miller, E.R., Yokoyama, M.T. and Ullrey, D.E. 1994. Calcium level affects the efficacy of supplemental microbial phytase in corn-soybean meal diets of weanling pigs. J. Anim. Sci., 72: 139-143.
39. Liu, J.D., Bollinger, W., Ledoux, D.R., Ellersieck, M.R. and Veum, T.L. 1997. Soaking increases the efficacy of supplemental microbial phytase in a low- phosphorus corn-soybean meal diet for growing pigs. J. Anim. Sci., 75: 1292-1298.
40. Lonnerdal, B., Bell, J.G., Hendrickx, A.G., Burns, R.A. and Keen, C.L. 1988. Effect of phytate removal on zinc absorption from soy formula. Am. J. Clin. Nutr., 48: 1301-1306.
41. Maga, J.A. 1982. Phytate: its chemistry, occurrence, food interactions, nutritional significance and methods of analysis. J. Agric. Food Chem., 30: 1-9.
42. Mahajan, A. and Dua, S. 1997. Nonchemical approach for reducing antinutritional factors in rapeseed and characterization of enzyme phytase. J. Agric. Food ChenL, 45: 2504-2508.
43. Mitchell, D.B., Vogel, K., Weimann, B.J., Pasamontes, L. and Van Loon, A.P.G.M. 1997. The phytase subfamily of histidine acid phosphatases: isolation of genes for two novel phytases from the fungi Aspergillus terreus and Myceliophthora thermophila. Microbiol., 143: 245-252.
44. Mitchell, R.D. and Edwards, H.M. 1996. Additive effects of 1,25-dihydroxycholecalciferol and phytase on phytate phosphorus utilization and related parameters in broiler chickens. Poult, Sci., 75: 111-119.
45. Mroz, Z., Jongbloed, A.W. and Kemme, P.A. 1994. Apparent digestibility and retention of nutrients bound to phytate complexes as influenced by microbial phytase and feeding regimen in pigs. J. Anim Sci., 72: 126-132.
46. Murry, A.C., Lewis, R.D. and Amos, H.E. 1997. The effect of microbial phytase in a pearl millet-soybean meal diet on apparent digestibility and retention of nutrients, serum mineral concentration, and bone mineral density of nursery pigs. J. Anim. Sci., 75: 1284-1291.
47. Nelson, T.S., Ferrara, L.W. and Storer, N.L. 1968. Phytate phosphorus contents of feed ingredients derived from plants. Poult. Sci., 47: 1372-1373.
48. Nelson, T.S., Shieh, T.R., Wodzinski, R.J. and Ware, J.H. 1971. Effect of supplemental phytase on the utilization of phytate phosphorus by chicks. J. Nutr., 101: 1289-1294.
49. Nolan, K.B., Duffin, P.A. and McWeeny, D.J. 1987. Effects of phytate on mineral bioavailability. In vitro studies on Mg, Ca, Fe, Cu and Zn (also Cd) solubilities in the presence of phytate. J. Sci. Food Agric., 40: 79-85.
50. Oberleas, D. 1973. Phytates. In: Toxicants occuring naturally in foods. National Academy of Sciences, Washington. D.C.: 363.
51. O’Dell, B.L. and Savage, J.E. 1960. Effects of phytic acid on zinc bioavailability. Proc. Soc. Exp. Biol. Med., 103: 304-305.
52. O’Quinn, P.R., Knabe, D.A. and Gregg, E.J, 1997. Efficacy of Natuphos in sorghum- based diets of finishing swine. J. Anim. Sci., 75: 1299-1307.
53. Pasamontes, L., Haiker, M., Wyss, M., Tessier, M. and Van Loon, A.P.G.M. 1997. Gene cloning, purification and characterization of a heat-stable phytase from the fungus Aspergillus fumigatus. Appl. Environ. Microbiol., 63:1696-1700.
54. Pointillart, A. 1991. Enhancement of phosphorus utilization in growing pigs fed phytate- rich diets by using rye bran. J. Anim. Sci., 69: 1109-1115.
55. Pointillart, A., Fontaine, N. and Thomasset, M. 1984. Phytate phosphorus utilization and intestinal phosphates in pigs fed low phosphorus: wheat or corn diets. Nutr. Rep. Int., 29: 473-483.
56. Porres, J.M., Stahl, C.H., Cheng, W.H., Fu, Y., Roneker, K.R., Pond, W.G. and Lei, X.G. 1999. Dietary intrinsic phytate protects colon from lipid peroxidation in pigs with a moderately high dietary iron intake. Proc. Soc. Exp. Biol. Med., 221: 80-85.
57. Qian, H., Kornegay, E.T. and Conner, D.E. 1996. Adverse effects of wide calcium: phosphorus ratios on supplemental phytase efficacy for weanling pigs fed two dietary phosphorus levels. J. Anim. Soi., 74: 1288-1297.
58. Qian, H., Kornegay, E.T. and Dendow, D.M. 1997. Utilization of phytate phosphorus and calcium as influenced by microbial phytase, choleccalciferol and the > calcium:total phosphorus ratio in broiler diets. Poult. Sci., 76: 37-46.
59. Radcliffe, J.S., Zhang, Z. and Kornegay, E.T. 1998. The effect of microbial phytase, citric acid and their interaction in a corn-soybean meal-based diet for weanling pigs. J. Anim. Sci., 76: 1880-1886.
60. Ravindran, V., Kornegay, E.T., Denbow, D.M., Yi, Z. and Hulet, R.M. 1995. Response of turkey poults to tiered levels of Natuphos phytase added to soybean meal-based semi-purified diets containing three levels of nonphytate phosphorus. Poult. Sci., 74: 1843-1854.
61. Reddy, N.R., Sathe, S.K. and Salukhe, D.K. 1982. Phytates in legumes and cereals. Advances in food research. Academic Press, N.Y., 28: 1-92.
62. Reinhold, J.G. 1971. High phytate content of rural Iranian bread: a possible cause of human zinc deficiency. Am. J. Clin. Nutr., 24: 1204-1206.
63. Roberson, K.D. and Edwards, H.M. 1994. Effects of 1,25-dihydroxycholecalciferol and phytase on zinc utilization in broiler chickens. Poult. Sci., 73: 1312-1326.
64. Rodriguez, E., Han, Y.M. and Lei, X.G. 1999. Cloning, sequencing and expression of an Escherichia coli acid phosphatase/phytase gene (app.A2) isolated from pig colon. Biochem. Biophys. Res. Comm., 257: 117-123.
65. Saha, P.R., Weaver, C.M. and Mason, A.C. 1994. Mineral bioavailability in rats from intrinsically labeled whole wheat flour of various phytate levels. J. Agric. Food Chem., 42: 2531-2535.
66. Sandberg, A.S. and Andersson, H. 1988. Effect of dietary phytase on the digestion of phytate in the stomach and the small intestine of humans. J. Nutr., 118: 469-473.
67. Sandberg, A.S., Carlsson, N.G. and Svanberg, U. 1989. Effects of inositol tri-, tetra-, penta- and hexaphosphates on in vitro estimation of iron availability. J. Food Sci., 54: 159-161.
68. Sebastian, S., Touchburn, S.P., Chavez, E.R. and Lague, P.C. 1996. The effects of supplemental microbial phytase on the performance and utilization of dietary calcium, phosphorus, copper and zinc in broiler chickens fed corn- soybean diets. Poult. Sci., 75: 729-736.
69. Simons, P.C.M., Versteegh, H.A.J., Jongbloed, A.W., Kemme, P.A., Slump, P., Bos, K.D., Wolters, M.G.E., Beudeker, R.F. and Verschoor, G.J. 1990. Improvement of phosphorus availability by microbial phytase in broilers and pigs. Brit. J. Nutr., 64: 525-540.
70. Stahl, C.H., Han, Y.M., Roneker, K.R., House, W.A. and Lei, X.G. 1999. Phytase improves iron bioavailability for hemoglobin synthesis in young pigs. J. Anim. Sci., 77: 2135-2142.
71. Stahl, C.H., Roneker, K.R., Thornton, J.R. and Lei, X.G. 2000. A new phytase expressed in yeast effectively improves the bioavailability of phytate phosphorus to weanling pigs. J. Anim. Sci., In press.
72. Sweeten, J.M. 1992. Livestock and poultry waste management: a national overview. In: National livestock, poultry and aquaculture waste management (Blake, J.D., Magette, W., Eds.). Amer. Soc. Agric. Eng., St. Joseph, MI, pages 4-15.
73. Ullah, A.H.J. 1988a. Production, rapid purrification and catalytic characterization of extracellular phytase from Aspergillus ficuum. Prep. Biochem., 18: 443-458.
74. Ullah, A.H.J. 1988b. Aspergillus ficuum phytase: partial primary structure, substrate selectivity and kinetic characterization. Prep. Biochem., 18: 459-471.
75. Ullah, A.H.J. and Gibson, D.M. 1987. Extracellular phytase (E.C.3.1.3.8) from Aspergillus ficuum NRRL 3135: purification and characterization. Prep. Biochem., 17: 63-91.
76. van Hartingsveldt, W., van Zeijl, C.M.J., Harteveld, G.M., Gouka, R.J., Suukerbuyk, M.G.E., Luiten, R.G.M., van Paridon, P.A., Selten, G.C.M., Veenstra, A.E., van Gorcom, R.F.M. and van den Hondel, A.M.J.J. 1993. Cloning, characterization and overexpression of the phytase-encoding gene (phyA) of Aspergillus niger. Gene, 127: 87-94.
77. Williams, P. J. and Taylor, T.G. 1985. A comparative study of phytate hydrolysis in the gastrointestinal tract of the golden hamster and the laboratory rat. Brit. J. Nutr., 54: 429-435.
78. Wodzinski, R.J. and Ullah, A.H.J. 1996. Phytase. Adv. Appl. Microbiol., 42: 263-302.
79. Wyss, M., Brugger, R., Kronenberger, A., Remy, R., Fimbel, R., Oesterhelt, G., Lehmann, M., van Loon, A.P.G.M. 1999. Biochemical characterization of fungal phytases (myo-inositol hexakisphosphate phosphohydrolases): catalytic properties. Appl. Environ. Microbiol., 65: 367-373.
80. Wyss, M., Pasamontes, L., Remy, R., Kohler, J., Kusznir, K., Gadient, M., Muller, F. and van Loon A.P.G.P. 1998. Comparison of the thermostability properties of three acid phosphatases from molds: Aspergillus fiunigatus phytase, A. niger phytase and A. niger pH 2.5 acid phosphatase. Appl. Environ. Microbiol., 64: 4446-4451.
81. Yi, Z., Kornegay, E.T. and Denbow, D.M. 1996a. Effect of microbial phytase on nitrogen and amino acid digestibility and nitrogen retention of turkey poults fed corn-soybean meal diets. Poult. Sci., 75: 979-990.
82. Yi, Z., Kornegay, E.T., Ravindran, V. and Denbow, D.M. 1996b. Improving phytate phosphorus availability in corn and soybean meal for broilers using microbial phytase and calculation of phosphorus equivalency values for phytase. Poult. Sci., 75: 240-249.
83. Yi, Z., Kornegay, E.T., Ravindran, V., Lindemann, M.D. and Wilson, J.H. 1996c. Effectiveness of Natuphos phytase in improving the bioavailabilities of phosphorus and other nutrients in soybean meal-based semipurified diets for young pigs. J. Anim. Sci., 74: 1601-1611.
84. Young, L.G., Leunissen, M. and Atkinson, J.L. 1993. Addition of microbial phytase to diets of young pigs. J. Anim. Sci., 71: 2147-2150.