-
1
-
-
0031444294
-
The cellular prion protein binds copper in vivo
-
9414160
-
Brown DR, Qin K, Herms JW, Madlung A, Manson J, Strome R, Fraser PE, Kruck T, Bohlen A von, Schulz-Schaeffer W, Giese A, Westaway D, Kretzschmar H (1997) The cellular prion protein binds copper in vivo. Nature 390:684-687 9414160
-
(1997)
Nature
, vol.390
, pp. 684-687
-
-
Brown, D.R.1
Qin, K.2
Herms, J.W.3
Madlung, A.4
Manson, J.5
Strome, R.6
Fraser, P.E.7
Kruck, T.8
Bohlen, A.9
von Schulz-Schaeffer, W.10
Giese, A.11
Westaway, D.12
Kretzschmar, H.13
-
2
-
-
0028876473
-
Neuropathological diagnostic criteria for Creutzfeldt-Jakob isease (CJD) and other human spongiform encephalopathies (prion diseases)
-
8974629
-
Budka H, Aguzzi A, Brown P, Brucher JM, Bugiani O, Gullotta F, Haltia M, Hauw JJ, Ironside JW, Jellinger K (1995) Neuropathological diagnostic criteria for Creutzfeldt-Jakob disease (CJD) and other human spongiform encephalopathies (prion diseases). Brain Pathol 5:459-466 8974629
-
(1995)
Brain Pathol.
, vol.5
, pp. 459-466
-
-
Budka, H.1
Aguzzi, A.2
Brown, P.3
Brucher, J.M.4
Bugiani, O.5
Gullotta, F.6
Haltia, M.7
Hauw, J.J.8
Ironside, J.W.9
Jellinger, K.10
-
3
-
-
0027531316
-
Beta PP participates in PrP-amyloid plaques of Gerstmann-Straussler-Scheinker disease, Indiana kindred
-
8093899
-
Bugiani O, Giaccone G, Verga L, Pollo B, Frangione B, Farlow MR, Tagliavini F, Ghetti B (1993) Beta PP participates in PrP-amyloid plaques of Gerstmann-Straussler-Scheinker disease, Indiana kindred. J Neuropathol Exp Neurol 52:64-70 8093899
-
(1993)
J. Neuropathol. Exp. Neurol.
, vol.52
, pp. 64-70
-
-
Bugiani, O.1
Giaccone, G.2
Verga, L.3
Pollo, B.4
Frangione, B.5
Farlow, M.R.6
Tagliavini, F.7
Ghetti, B.8
-
4
-
-
0035879693
-
Active glycation in neurofibrillary pathology of Alzheimer disease: N (epsilon)-(carboxymethyl) lysine and hexitol-lysine
-
10.1016/S0891-5849(01)00570-6
-
Castellani RJ, Harris PL, Sayre LM, Fujii J, Taniguchi N, Vitek MP, Founds H, Atwood CS, Perry G, Smith MA (2001) Active glycation in neurofibrillary pathology of Alzheimer disease: N (epsilon)-(carboxymethyl) lysine and hexitol-lysine. Free Radic Biol Med 31:175-180 10.1016/S0891-5849(01)00570-6
-
(2001)
Free Radic. Biol. Med.
, vol.31
, pp. 175-180
-
-
Castellani, R.J.1
Harris, P.L.2
Sayre, L.M.3
Fujii, J.4
Taniguchi, N.5
Vitek, M.P.6
Founds, H.7
Atwood, C.S.8
Perry, G.9
Smith, M.A.10
-
6
-
-
0034110873
-
Cerebral amyloidosis in prion diseases
-
10842694
-
DeArmond SJ (2000) Cerebral amyloidosis in prion diseases. Amyloid 7:3-6 10842694
-
(2000)
Amyloid
, vol.7
, pp. 3-6
-
-
DeArmond, S.J.1
-
7
-
-
13844292518
-
Changed iron regulation in scrapie-infected neuroblastoma cells
-
10.1016/j.molbrainres.2004.10.018
-
Fernaeus S, Halldin J, Bedecs K, Land T (2005) Changed iron regulation in scrapie-infected neuroblastoma cells. Brain Res Mol Brain Res 133:266-273 10.1016/j.molbrainres.2004.10.018
-
(2005)
Brain Res. Mol. Brain Res.
, vol.133
, pp. 266-273
-
-
Fernaeus, S.1
Halldin, J.2
Bedecs, K.3
Land, T.4
-
8
-
-
0033002350
-
Nuclear DNA fragmentation in Creutzfeldt-Jakob disease: Does a mere positive in situ nuclear end-labeling indicate apoptosis?
-
9930889
-
Ferrer I (1999) Nuclear DNA fragmentation in Creutzfeldt-Jakob disease: does a mere positive in situ nuclear end-labeling indicate apoptosis? Acta Neuropathol 97:5-12 9930889
-
(1999)
Acta Neuropathol.
, vol.97
, pp. 5-12
-
-
Ferrer, I.1
-
9
-
-
0141514771
-
Sporadic and familial CJD: Classification and characterisation
-
10.1093/bmb/66.1.213
-
Gambetti P, Kong Q, Zou W, Parchi P, Chen SG (2003) Sporadic and familial CJD: Classification and characterisation. Br Med Bull 66:213-239 10.1093/bmb/66.1.213
-
(2003)
Br. Med. Bull.
, vol.66
, pp. 213-239
-
-
Gambetti, P.1
Kong, Q.2
Zou, W.3
Parchi, P.4
Chen, S.G.5
-
10
-
-
0024856333
-
Gerstmann-Straussler-Scheinker disease. II. Neurofibrillary tangles and plaques with PrP-amyloid coexist in an affected family
-
2573006
-
Ghetti B, Tagliavini F, Masters CL, Beyreuther K, Giaccone G, Verga L, Farlow MR, Conneally PM, Dlouhy SR, Azzarelli B (1989) Gerstmann-Straussler-Scheinker disease. II. Neurofibrillary tangles and plaques with PrP-amyloid coexist in an affected family. Neurology 39:1453-1461 2573006
-
(1989)
Neurology
, vol.39
, pp. 1453-1461
-
-
Ghetti, B.1
Tagliavini, F.2
Masters, C.L.3
Beyreuther, K.4
Giaccone, G.5
Verga, L.6
Farlow, M.R.7
Conneally, P.M.8
Dlouhy, S.R.9
Azzarelli, B.10
-
11
-
-
1642518575
-
Hereditary prion protein amyloidoses
-
10.1016/S0272-2712(02)00064-1 viii
-
Ghetti B, Tagliavini F, Takao M, Bugiani O, Piccardo P (2003) Hereditary prion protein amyloidoses. Clin Lab Med 23:65-85, viii 10.1016/ S0272-2712(02)00064-1
-
(2003)
Clin. Lab. Med.
, vol.23
, pp. 65-85
-
-
Ghetti, B.1
Tagliavini, F.2
Takao, M.3
Bugiani, O.4
Piccardo, P.5
-
12
-
-
0032726882
-
Selective neuronal vulnerability in human prion diseases. Fatal familial insomnia differs from other types of prion diseases
-
10550300
-
Guentchev M, Wanschitz J, Voigtlander T, Flicker H, Budka H (1999) Selective neuronal vulnerability in human prion diseases. Fatal familial insomnia differs from other types of prion diseases. Am J Pathol 155:1453-1457 10550300
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 1453-1457
-
-
Guentchev, M.1
Wanschitz, J.2
Voigtlander, T.3
Flicker, H.4
Budka, H.5
-
13
-
-
0033826082
-
Evidence for oxidative stress in experimental prion disease
-
10964599
-
Guentchev M, Voigtlander T, Haberler C, Groschup MH, Budka H (2000) Evidence for oxidative stress in experimental prion disease. Neurobiol Dis 7:270-273 10964599
-
(2000)
Neurobiol. Dis.
, vol.7
, pp. 270-273
-
-
Guentchev, M.1
Voigtlander, T.2
Haberler, C.3
Groschup, M.H.4
Budka, H.5
-
14
-
-
0036236406
-
Oxidative damage to nucleic acids in human prion disease
-
10.1006/nbdi.2002.0477
-
Guentchev M, Siedlak SL, Jarius C, Tagliavini F, Castellani RJ, Perry G, Smith MA, Budka H (2002) Oxidative damage to nucleic acids in human prion disease. Neurobiol Dis 9:275-281 10.1006/nbdi.2002.0477
-
(2002)
Neurobiol. Dis.
, vol.9
, pp. 275-281
-
-
Guentchev, M.1
Siedlak, S.L.2
Jarius, C.3
Tagliavini, F.4
Castellani, R.J.5
Perry, G.6
Smith, M.A.7
Budka, H.8
-
15
-
-
0842332840
-
Silent prions lying in wait: A two-hit model of prion/amyloid formation and infection
-
10.1016/j.jmb.2003.12.004
-
Hall D, Edskes H (2004) Silent prions lying in wait: A two-hit model of prion/amyloid formation and infection. J Mol Biol 336:775-786 10.1016/ j.jmb.2003.12.004
-
(2004)
J. Mol. Biol.
, vol.336
, pp. 775-786
-
-
Hall, D.1
Edskes, H.2
-
16
-
-
0035341254
-
Mitochondrial abnormalities in Alzheimer's disease
-
11312286
-
Hirai K, Aliev G, Nunomura A, Fujioka H, Russell RL, Atwood CS, Johnson AB, Kress Y, Vinters HV, Tabaton M, Shimohama S, Cash AD, Siedlak SL, Harris PL, Jones PK, Petersen RB, Perry G, Smith MA (2001) Mitochondrial abnormalities in Alzheimer's disease. J Neurosci 21:3017-3023 11312286
-
(2001)
J. Neurosci.
, vol.21
, pp. 3017-3023
-
-
Hirai, K.1
Aliev, G.2
Nunomura, A.3
Fujioka, H.4
Russell, R.L.5
Atwood, C.S.6
Johnson, A.B.7
Kress, Y.8
Vinters, H.V.9
Tabaton, M.10
Shimohama, S.11
Cash, A.D.12
Siedlak, S.L.13
Harris, P.L.14
Jones, P.K.15
Petersen, R.B.16
Perry, G.17
Smith, M.A.18
-
17
-
-
20444383489
-
Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron
-
[Mar 14; Epub ahead of print]
-
Honda K, Smith MA, Zhu X, Baus D, Merrick WC, Tartakoff AM, Hattier T, Harris PL, Siedlak SL, Fujioka H, Liu Q, Moreira PI, Miller FP, Nunomura A, Shimohama S, Perry G (2005) Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. J Biol Chem [Mar 14; Epub ahead of print]
-
(2005)
J. Biol. Chem.
-
-
Honda, K.1
Smith, M.A.2
Zhu, X.3
Baus, D.4
Merrick, W.C.5
Tartakoff, A.M.6
Hattier, T.7
Harris, P.L.8
Siedlak, S.L.9
Fujioka, H.10
Liu, Q.11
Moreira, P.I.12
Miller, F.P.13
Nunomura, A.14
Shimohama, S.15
Perry, G.16
-
18
-
-
0345621492
-
Pathology of variant Creutzfeldt-Jakob disease
-
Ironside JW (2000) Pathology of variant Creutzfeldt-Jakob disease. Arch Virol Suppl (16):143-151
-
(2000)
Arch. Virol. Suppl.
, Issue.16
, pp. 143-151
-
-
Ironside, J.W.1
-
19
-
-
0023499868
-
Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins
-
2446004
-
Kascsak RJ, Rubenstein R, Merz PA, Tonna-DeMasi M, Fersko R, Carp RI, Wisniewski HM, Diringer H (1987) Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins. J Virol 61:3688-3693 446004
-
(1987)
J. Virol.
, vol.61
, pp. 3688-3693
-
-
Kascsak, R.J.1
Rubenstein, R.2
Merz, P.A.3
Tonna-DeMasi, M.4
Fersko, R.5
Carp, R.I.6
Wisniewski, H.M.7
Diringer, H.8
-
21
-
-
17144456296
-
Diagnosis of prion diseases
-
10.1093/bmb/66.1.267
-
Kubler E, Oesch B, Raeber AJ (2003) Diagnosis of prion diseases. Br Med Bull 66:267-279 10.1093/bmb/66.1.267
-
(2003)
Br. Med. Bull.
, vol.66
, pp. 267-279
-
-
Kubler, E.1
Oesch, B.2
Raeber, A.J.3
-
22
-
-
0030908160
-
Internucleosomal breakdown of the DNA of brain cortex in human spongiform encephalopathy
-
10.1016/S0197-0186(96)00153-2
-
Lucas M, Izquierdo G, Munoz C, Solano F (1997) Internucleosomal breakdown of the DNA of brain cortex in human spongiform encephalopathy. Neurochem Int 31:241-244 10.1016/S0197-0186(96)00153-2
-
(1997)
Neurochem. Int.
, vol.31
, pp. 241-244
-
-
Lucas, M.1
Izquierdo, G.2
Munoz, C.3
Solano, F.4
-
23
-
-
10644241804
-
Protease-resistant human prion protein and ferritin are cotransported across Caco-2 epithelial cells: Implications for species barrier in prion uptake from the intestine
-
10.1523/JNEUROSCI.2864-04.2004
-
Mishra RS, Basu S, Gu Y, Luo X, Zou WQ, Mishra R, Li R, Chen SG, Gambetti P, Fujioka H, Singh N (2004) Protease-resistant human prion protein and ferritin are cotransported across Caco-2 epithelial cells: implications for species barrier in prion uptake from the intestine. J Neurosci 24:11280-11290 10.1523/JNEUROSCI.2864-04.2004
-
(2004)
J. Neurosci.
, vol.24
, pp. 11280-11290
-
-
Mishra, R.S.1
Basu, S.2
Gu, Y.3
Luo, X.4
Zou, W.Q.5
Mishra, R.6
Li, R.7
Chen, S.G.8
Gambetti, P.9
Fujioka, H.10
Singh, N.11
-
24
-
-
0033559462
-
RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease
-
10066249
-
Nunomura A, Perry G, Pappolla MA, Wade R, Hirai K, Chiba S, Smith MA (1999) RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. J Neurosci 19:1959-1964 10066249
-
(1999)
J. Neurosci.
, vol.19
, pp. 1959-1964
-
-
Nunomura, A.1
Perry, G.2
Pappolla, M.A.3
Wade, R.4
Hirai, K.5
Chiba, S.6
Smith, M.A.7
-
25
-
-
0033758324
-
Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome
-
11089579
-
Nunomura A, Perry G, Pappolla MA, Friedland RP, Hirai K, Chiba S, Smith MA (2000) Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome. J Neuropathol Exp Neurol 59:1011-1017 11089579
-
(2000)
J. Neuropathol. Exp. Neurol.
, vol.59
, pp. 1011-1017
-
-
Nunomura, A.1
Perry, G.2
Pappolla, M.A.3
Friedland, R.P.4
Hirai, K.5
Chiba, S.6
Smith, M.A.7
-
26
-
-
0036113819
-
The role of iron and copper in the aetiology of neurodegenerative disorders: Therapeutic implications
-
11994023
-
Perry G, Sayre LM, Atwood CS, Castellani RJ, Cash AD, Rottkamp CA, Smith MA (2002) The role of iron and copper in the aetiology of neurodegenerative disorders: Therapeutic implications. CNS Drugs 16:339-352 11994023
-
(2002)
CNS Drugs
, vol.16
, pp. 339-352
-
-
Perry, G.1
Sayre, L.M.2
Atwood, C.S.3
Castellani, R.J.4
Cash, A.D.5
Rottkamp, C.A.6
Smith, M.A.7
-
27
-
-
0028973317
-
Gerstmann-Straussler-Scheinker disease (PRNP P102L): Amyloid deposits are best recognized by antibodies directed to epitopes in PrP region 90-165
-
7595652
-
Piccardo P, Ghetti B, Dickson DW, Vinters HV, Giaccone G, Bugiani O, Tagliavini F, Young K, Dlouhy SR, Seiler C, et al (1995) Gerstmann-Straussler-Scheinker disease (PRNP P102L): Amyloid deposits are best recognized by antibodies directed to epitopes in PrP region 90-165. J Neuropathol Exp Neurol 54:790-801 7595652
-
(1995)
J. Neuropathol. Exp. Neurol.
, vol.54
, pp. 790-801
-
-
Piccardo, P.1
Ghetti, B.2
Dickson, D.W.3
Vinters, H.V.4
Giaccone, G.5
Bugiani, O.6
Tagliavini, F.7
Young, K.8
Dlouhy, S.R.9
Seiler, C.10
-
28
-
-
0032506187
-
Prions
-
10.1073/pnas.95.23.13363
-
Prusiner SB (1998) Prions. Proc Natl Acad Sci USA 95:13363-13383 10.1073/ pnas.95.23.13363
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13363-13383
-
-
Prusiner, S.B.1
-
29
-
-
0037715143
-
Expression of prion protein increases cellular copper binding and antioxidant enzyme activities but not copper delivery
-
10.1074/jbc.M211830200
-
Rachidi W, Vilette D, Guiraud P, Arlotto M, Riondel J, Laude H, Lehmann S, Favier A (2003) Expression of prion protein increases cellular copper binding and antioxidant enzyme activities but not copper delivery. J Biol Chem 278:9064-9072 10.1074/jbc.M211830200
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 9064-9072
-
-
Rachidi, W.1
Vilette, D.2
Guiraud, P.3
Arlotto, M.4
Riondel, J.5
Laude, H.6
Lehmann, S.7
Favier, A.8
-
30
-
-
0346729697
-
Neuroprotective functions of prion protein
-
10.1002/jnr.10864
-
Roucou X, Gains M, LeBlanc AC (2004) Neuroprotective functions of prion protein. J Neurosci Res 75:153-161 10.1002/jnr.10864
-
(2004)
J. Neurosci. Res.
, vol.75
, pp. 153-161
-
-
Roucou, X.1
Gains, M.2
LeBlanc, A.C.3
-
31
-
-
0030989545
-
4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease
-
9109537
-
Sayre LM, Zelasko DA, Harris PL, Perry G, Salomon RG, Smith MA (1997) 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J Neurochem 68:2092-2097 9109537
-
(1997)
J. Neurochem.
, vol.68
, pp. 2092-2097
-
-
Sayre, L.M.1
Zelasko, D.A.2
Harris, P.L.3
Perry, G.4
Salomon, R.G.5
Smith, M.A.6
-
32
-
-
0032847544
-
In situ methods for detection and localization of markers of oxidative stress: Application in neurodegenerative disorders
-
10507022
-
Sayre LM, Perry G, Smith MA (1999) In situ methods for detection and localization of markers of oxidative stress: Application in neurodegenerative disorders. Methods Enzymol 309:133-152 10507022
-
(1999)
Methods Enzymol.
, vol.309
, pp. 133-152
-
-
Sayre, L.M.1
Perry, G.2
Smith, M.A.3
-
34
-
-
0345306739
-
Copper chelation delays the onset of prion disease
-
10.1074/jbc.C300303200
-
Sigurdsson EM, Brown DR, Alim MA, Scholtzova H, Carp R, Meeker HC, Prelli F, Frangione B, Wisniewski T (2003) Copper chelation delays the onset of prion disease. J Biol Chem 278:46199-46202 10.1074/ jbc.C300303200
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 46199-46202
-
-
Sigurdsson, E.M.1
Brown, D.R.2
Alim, M.A.3
Scholtzova, H.4
Carp, R.5
Meeker, H.C.6
Prelli, F.7
Frangione, B.8
Wisniewski, T.9
-
35
-
-
0028304705
-
Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease
-
8030754
-
Smith MA, Kutty RK, Richey PL, Yan SD, Stern D, Chader GJ, Wiggert B, Petersen RB, Perry G (1994) Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease. Am J Pathol 145:42-47 8030754
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 42-47
-
-
Smith, M.A.1
Kutty, R.K.2
Richey, P.L.3
Yan, S.D.4
Stern, D.5
Chader, G.J.6
Wiggert, B.7
Petersen, R.B.8
Perry, G.9
-
36
-
-
0030885482
-
Iron accumulation in Alzheimer disease is a source of redox-generated free radicals
-
10.1073/pnas.94.18.9866
-
Smith MA, Harris PL, Sayre LM, Perry G (1997) Iron accumulation in Alzheimer disease is a source of redox-generated free radicals. Proc Natl Acad Sci USA 94:9866-9868 10.1073/pnas.94.18.9866
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9866-9868
-
-
Smith, M.A.1
Harris, P.L.2
Sayre, L.M.3
Perry, G.4
-
37
-
-
0037083888
-
Metal imbalance and compromised antioxidant function are early changes in prion disease
-
11829763
-
Thackray AM, Knight R, Haswell SJ, Bujdoso R, Brown DR (2002) Metal imbalance and compromised antioxidant function are early changes in prion disease. Biochem J 362:253-258 11829763
-
(2002)
Biochem. J.
, vol.362
, pp. 253-258
-
-
Thackray, A.M.1
Knight, R.2
Haswell, S.J.3
Bujdoso, R.4
Brown, D.R.5
-
38
-
-
0034810585
-
Aberrant metal binding by prion protein in human prion disease
-
10.1046/j.1471-4159.2001.00522.x
-
Wong BS, Chen SG, Colucci M, Xie Z, Pan T, Liu T, Li R, Gambetti P, Sy MS, Brown DR (2001) Aberrant metal binding by prion protein in human prion disease. J Neurochem 78:1400-1408 10.1046/j.1471-4159.2001.00522.x
-
(2001)
J. Neurochem.
, vol.78
, pp. 1400-1408
-
-
Wong, B.S.1
Chen, S.G.2
Colucci, M.3
Xie, Z.4
Pan, T.5
Liu, T.6
Li, R.7
Gambetti, P.8
Sy, M.S.9
Brown, D.R.10
-
39
-
-
0035145614
-
Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein
-
10.1046/j.1471-4159.2001.00028.x
-
Wong BS, Liu T, Li R, Pan T, Petersen RB, Smith MA, Gambetti P, Perry G, Manson JC, Brown DR, Sy MS (2001) Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein. J Neurochem 76:565-572 10.1046/j.1471-4159.2001.00028.x
-
(2001)
J. Neurochem.
, vol.76
, pp. 565-572
-
-
Wong, B.S.1
Liu, T.2
Li, R.3
Pan, T.4
Petersen, R.B.5
Smith, M.A.6
Gambetti, P.7
Perry, G.8
Manson, J.C.9
Brown, D.R.10
Sy, M.S.11
-
40
-
-
0035025086
-
Induction of HO-1 and NOS in doppel-expressing mice devoid of PrP: Implications for doppel function
-
11312611
-
Wong BS, Liu T, Paisley D, Li R, Pan T, Chen SG, Perry G, Petersen RB, Smith MA, Melton DW, Gambetti P, Brown DR, Sy MS (2001) Induction of HO-1 and NOS in doppel-expressing mice devoid of PrP: Implications for doppel function. Mol Cell Neurosci 17:768-775 11312611
-
(2001)
Mol. Cell Neurosci.
, vol.17
, pp. 768-775
-
-
Wong, B.S.1
Liu, T.2
Paisley, D.3
Li, R.4
Pan, T.5
Chen, S.G.6
Perry, G.7
Petersen, R.B.8
Smith, M.A.9
Melton, D.W.10
Gambetti, P.11
Brown, D.R.12
Sy, M.S.13
-
41
-
-
0034797352
-
Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: The 'two hit' hypothesis
-
10.1016/S0047-6374(01)00342-6
-
Zhu X, Castellani RJ, Takeda A, Nunomura A, Atwood CS, Perry G, Smith MA (2001) Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: The 'two hit' hypothesis. Mech Ageing Dev 123:39-46 10.1016/S0047-6374(01)00342-6
-
(2001)
Mech. Ageing Dev.
, vol.123
, pp. 39-46
-
-
Zhu, X.1
Castellani, R.J.2
Takeda, A.3
Nunomura, A.4
Atwood, C.S.5
Perry, G.6
Smith, M.A.7
-
42
-
-
1642358352
-
Alzheimer's disease: The two-hit hypothesis
-
10.1016/S1474-4422(04)00707-0
-
Zhu X, Raina AK, Perry G, Smith MA (2004) Alzheimer's disease: The two-hit hypothesis. Lancet Neurol 3:219-226 10.1016/S1474-4422(04)00707-0
-
(2004)
Lancet Neurol.
, vol.3
, pp. 219-226
-
-
Zhu, X.1
Raina, A.K.2
Perry, G.3
Smith, M.A.4
|