-
1
-
-
0035843170
-
Industrial biocatalysis today and tomorrow
-
Schmid, A. et al. Industrial biocatalysis today and tomorrow. Nature 409, 258-268 (2001).
-
(2001)
Nature
, vol.409
, pp. 258-268
-
-
Schmid, A.1
-
2
-
-
0042432086
-
Directed evolution of industrial enzymes: An update
-
Cherry, J. R. & Fidantsef, A. L. Directed evolution of industrial enzymes: an update. Curr. Opin. Biotechnol. 14, 438-443 (2003).
-
(2003)
Curr. Opin. Biotechnol
, vol.14
, pp. 438-443
-
-
Cherry, J.R.1
Fidantsef, A.L.2
-
3
-
-
3543087310
-
Trends and innovations in industrial biocatalysis for the production of fine chemicals
-
Panke, S., Held, M. & Wubbolts, M. Trends and innovations in industrial biocatalysis for the production of fine chemicals. Curr. Opin. Biotechnol. 15, 272-279 (2004).
-
(2004)
Curr. Opin. Biotechnol
, vol.15
, pp. 272-279
-
-
Panke, S.1
Held, M.2
Wubbolts, M.3
-
4
-
-
23044501802
-
Evolving strategies for enzyme engineering
-
Bloom, J. D. et al. Evolving strategies for enzyme engineering. Curr. Opin. Struct. Biol. 15, 447-452 (2005).
-
(2005)
Curr. Opin. Struct. Biol
, vol.15
, pp. 447-452
-
-
Bloom, J.D.1
-
5
-
-
13844250741
-
High-throughput screens and selections of enzyme-encoding genes
-
Aharoni, A., Griffiths, A. D. & Tawfik, D. S. High-throughput screens and selections of enzyme-encoding genes. Curr. Opin. Chem. Biol. 9, 210-216 (2005).
-
(2005)
Curr. Opin. Chem. Biol
, vol.9
, pp. 210-216
-
-
Aharoni, A.1
Griffiths, A.D.2
Tawfik, D.S.3
-
6
-
-
0035807809
-
Enzyme-like proteins by computational design
-
Bolon, D. N. & Mayo, S. L. Enzyme-like proteins by computational design. Proc. Natl Acad. Sci. USA 98, 14274-14279 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 14274-14279
-
-
Bolon, D.N.1
Mayo, S.L.2
-
7
-
-
3042655537
-
Computational design of a biologically active enzyme
-
Dwyer, M. A., Looger, L. L. & Hellinga, H. W. Computational design of a biologically active enzyme. Science 304, 1967-1971 (2004).
-
(2004)
Science
, vol.304
, pp. 1967-1971
-
-
Dwyer, M.A.1
Looger, L.L.2
Hellinga, H.W.3
-
8
-
-
31544477181
-
Design and evolution of new catalytic activity with an existing protein scaffold
-
Park, H. S. et al. Design and evolution of new catalytic activity with an existing protein scaffold. Science 311, 535-538 (2006).
-
(2006)
Science
, vol.311
, pp. 535-538
-
-
Park, H.S.1
-
9
-
-
0038023153
-
Turnover-based in vitro selection and evolution of biocatalysts from a fully synthetic antibody library
-
Cesaro-Tadic, S. et al. Turnover-based in vitro selection and evolution of biocatalysts from a fully synthetic antibody library. Nature Biotechnol. 21, 679-685 (2003).
-
(2003)
Nature Biotechnol
, vol.21
, pp. 679-685
-
-
Cesaro-Tadic, S.1
-
10
-
-
4544371858
-
Catalytic antibodies: Hapten design strategies and screening methods
-
Xu, Y., Yamamoto, N. & Janda, K. D. Catalytic antibodies: hapten design strategies and screening methods. Bioorg. Med. Chem. 12, 5247-5268 (2004).
-
(2004)
Bioorg. Med. Chem
, vol.12
, pp. 5247-5268
-
-
Xu, Y.1
Yamamoto, N.2
Janda, K.D.3
-
11
-
-
0030817279
-
RNA-peptide fusions for the in vitro selection of peptides and proteins
-
Roberts, R. W. & Szostak, J. W. RNA-peptide fusions for the in vitro selection of peptides and proteins. Proc. Natl Acad. Sci. USA 94, 12297-12302 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 12297-12302
-
-
Roberts, R.W.1
Szostak, J.W.2
-
12
-
-
0035810165
-
Functional proteins from a random-sequence library
-
Keefe, A. D. & Szostak, J. W. Functional proteins from a random-sequence library. Nature 410, 715-718 (2001).
-
(2001)
Nature
, vol.410
, pp. 715-718
-
-
Keefe, A.D.1
Szostak, J.W.2
-
13
-
-
0035957374
-
The use of mRNA display to select high-affinity protein-binding peptides
-
Wilson, D. S., Keefe, A. D. & Szostak, J. W. The use of mRNA display to select high-affinity protein-binding peptides. Proc. Natl Acad. Sci. USA 98, 3750-3755 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 3750-3755
-
-
Wilson, D.S.1
Keefe, A.D.2
Szostak, J.W.3
-
14
-
-
0035994074
-
Identification of epitope-like consensus motifs using mRNA display
-
Baggio, R. et al. Identification of epitope-like consensus motifs using mRNA display. J. Mol. Recognit. 15, 126-134 (2002).
-
(2002)
J. Mol. Recognit
, vol.15
, pp. 126-134
-
-
Baggio, R.1
-
15
-
-
0036008852
-
Selection of v-abl tyrosine kinase substrate sequences from randomized peptide and cellular proteomic libraries using mRNA display
-
Cujec, T. P., Medeiros, P. F., Hammond, P., Rise, C. & Kreider, B. L. Selection of v-abl tyrosine kinase substrate sequences from randomized peptide and cellular proteomic libraries using mRNA display. Chem. Biol. 9, 253-264 (2002).
-
(2002)
Chem. Biol
, vol.9
, pp. 253-264
-
-
Cujec, T.P.1
Medeiros, P.F.2
Hammond, P.3
Rise, C.4
Kreider, B.L.5
-
16
-
-
0037253816
-
A novel class of small functional peptides that bind and inhibit human alpha-thrombin isolated by mRNA display
-
Raffler, N. A., Schneider-Mergener, J. & Famulok, M. A novel class of small functional peptides that bind and inhibit human alpha-thrombin isolated by mRNA display. Chem. Biol. 10, 69-79 (2003).
-
(2003)
Chem. Biol
, vol.10
, pp. 69-79
-
-
Raffler, N.A.1
Schneider-Mergener, J.2
Famulok, M.3
-
17
-
-
18544397601
-
Directed evolution of high-affinity antibody mimics using mRNA display
-
Xu, L. H. et al. Directed evolution of high-affinity antibody mimics using mRNA display. Chem. Biol. 9, 933-942 (2002).
-
(2002)
Chem. Biol
, vol.9
, pp. 933-942
-
-
Xu, L.H.1
-
18
-
-
32844460390
-
Directed evolution of ATP binding proteins from a zinc finger domain by using mRNA display
-
Cho, G. S. & Szostak, J. W. Directed evolution of ATP binding proteins from a zinc finger domain by using mRNA display. Chem. Biol. 13, 139-147 (2006).
-
(2006)
Chem. Biol
, vol.13
, pp. 139-147
-
-
Cho, G.S.1
Szostak, J.W.2
-
19
-
-
0032516801
-
High-resolution solution structure of the retinoid X receptor DNA-binding domain
-
Holmbeck, S. M. A. et al. High-resolution solution structure of the retinoid X receptor DNA-binding domain. J. Mol. Biol. 281, 271-284 (1998).
-
(1998)
J. Mol. Biol
, vol.281
, pp. 271-284
-
-
Holmbeck, S.M.A.1
-
20
-
-
85045502002
-
Randomization of genes by PCR mutagenesis
-
Cadwell, R. C. & Joyce, G. F. Randomization of genes by PCR mutagenesis. PCR Methods Appl. 2, 28-33 (1992).
-
(1992)
PCR Methods Appl
, vol.2
, pp. 28-33
-
-
Cadwell, R.C.1
Joyce, G.F.2
-
21
-
-
84945517574
-
-
Wilson, D. S. & Keefe, A. D. in Current Protocols in Molecular Biology (eds Ausubel, F. et al.) Suppl. 51, unit 8.3 (Wiley, New York, 2000).
-
Wilson, D. S. & Keefe, A. D. in Current Protocols in Molecular Biology (eds Ausubel, F. et al.) Suppl. 51, unit 8.3 (Wiley, New York, 2000).
-
-
-
-
22
-
-
33847659368
-
Identification of new tag sequences with differential and selective recognition properties for the anti-FLAG monoclonal antibodies M1, M2 and M5
-
Slootstra, J. W., Kuperus, D., Pluckthun, A. & Meloen, R. H. Identification of new tag sequences with differential and selective recognition properties for the anti-FLAG monoclonal antibodies M1, M2 and M5. Mol. Divers. 2, 156-164 (1997).
-
(1997)
Mol. Divers
, vol.2
, pp. 156-164
-
-
Slootstra, J.W.1
Kuperus, D.2
Pluckthun, A.3
Meloen, R.H.4
-
23
-
-
0030003509
-
Kinetic and mechanistic analysis of nonenzymatic, template-directed oligoribonucleotide ligation
-
Rohatgi, R., Bartel, D. P. & Szostak, J. W. Kinetic and mechanistic analysis of nonenzymatic, template-directed oligoribonucleotide ligation. J. Am. Chem. Soc. 118, 3332-3339 (1996).
-
(1996)
J. Am. Chem. Soc
, vol.118
, pp. 3332-3339
-
-
Rohatgi, R.1
Bartel, D.P.2
Szostak, J.W.3
-
24
-
-
0033908031
-
Man-made enzymes - from design to in vitro compartmentalisation
-
Griffiths, A. D. & Tawfik, D. S. Man-made enzymes - from design to in vitro compartmentalisation. Curr. Opin. Biotechnol. 11, 338-353 (2000).
-
(2000)
Curr. Opin. Biotechnol
, vol.11
, pp. 338-353
-
-
Griffiths, A.D.1
Tawfik, D.S.2
-
25
-
-
33845558534
-
On the mechanism of T4 RNA ligase
-
Bryant, F. R. & Benkovic, S. J. On the mechanism of T4 RNA ligase. J. Am. Chem. Soc. 103, 696-697 (1981).
-
(1981)
J. Am. Chem. Soc
, vol.103
, pp. 696-697
-
-
Bryant, F.R.1
Benkovic, S.J.2
-
26
-
-
0028027513
-
Characterization of a set of T7 RNA-polymerase active site mutants
-
Bonner, G., Lafer, E. M. & Sousa, R. Characterization of a set of T7 RNA-polymerase active site mutants. J. Biol. Chem. 269, 25120-25128 (1994).
-
(1994)
J. Biol. Chem
, vol.269
, pp. 25120-25128
-
-
Bonner, G.1
Lafer, E.M.2
Sousa, R.3
-
27
-
-
0027488624
-
Isolation of new ribozymes from a large pool of random sequences
-
Bartel, D. P. & Szostak, J. W. Isolation of new ribozymes from a large pool of random sequences. Science 261, 1411-1418 (1993).
-
(1993)
Science
, vol.261
, pp. 1411-1418
-
-
Bartel, D.P.1
Szostak, J.W.2
-
28
-
-
25444501848
-
General deoxyribozyme-catalyzed synthesis of native 3′-5′ RNA linkages
-
Purtha, W. E., Coppins, R. L., Smalley, M. K. & Silverman, S. K. General deoxyribozyme-catalyzed synthesis of native 3′-5′ RNA linkages. J. Am. Chem. Soc. 127, 13124-13125 (2005).
-
(2005)
J. Am. Chem. Soc
, vol.127
, pp. 13124-13125
-
-
Purtha, W.E.1
Coppins, R.L.2
Smalley, M.K.3
Silverman, S.K.4
-
29
-
-
0029147392
-
Structurally complex and highly-active RNA ligases derived from random RNA sequences
-
Ekland, E. H., Szostak, J. W. & Bartel, D. P. Structurally complex and highly-active RNA ligases derived from random RNA sequences. Science 269, 364-370 (1995).
-
(1995)
Science
, vol.269
, pp. 364-370
-
-
Ekland, E.H.1
Szostak, J.W.2
Bartel, D.P.3
-
30
-
-
0017760011
-
Micro thin-layer techniques for rapid sequence-analysis of P-32-Labeled RNA - double digestion and pancreatic ribonuclease analyses
-
Volckaert, G. & Fiers, W. Micro thin-layer techniques for rapid sequence-analysis of P-32-Labeled RNA - double digestion and pancreatic ribonuclease analyses. Anal. Biochem. 83, 228-239 (1977).
-
(1977)
Anal. Biochem
, vol.83
, pp. 228-239
-
-
Volckaert, G.1
Fiers, W.2
-
31
-
-
0026680843
-
Site-specific modification of pre-messenger-RNA - the 2′-hydroxyl groups at the splice sites
-
Moore, M. J. & Sharp, P. A. Site-specific modification of pre-messenger-RNA - the 2′-hydroxyl groups at the splice sites. Science 256, 992-997 (1992).
-
(1992)
Science
, vol.256
, pp. 992-997
-
-
Moore, M.J.1
Sharp, P.A.2
-
32
-
-
17544399298
-
Psoralen photo-crosslinked mRNA-puromycin conjugates: A novel template for the rapid and facile preparation of mRNA-protein fusions
-
Kurz, M., Gu, K. & Lohse, P. A. Psoralen photo-crosslinked mRNA-puromycin conjugates: a novel template for the rapid and facile preparation of mRNA-protein fusions. Nucleic Acids Res. 28, e83 (2000).
-
(2000)
Nucleic Acids Res
, vol.28
-
-
Kurz, M.1
Gu, K.2
Lohse, P.A.3
-
33
-
-
0034708337
-
Constructing high complexity synthetic libraries of long ORFs using in vitro selection
-
Cho, G., Keefe, A. D., Liu, R. H., Wilson, D. S. & Szostak, J. W. Constructing high complexity synthetic libraries of long ORFs using in vitro selection. J. Mol. Biol. 297, 309-319 (2000).
-
(2000)
J. Mol. Biol
, vol.297
, pp. 309-319
-
-
Cho, G.1
Keefe, A.D.2
Liu, R.H.3
Wilson, D.S.4
Szostak, J.W.5
-
34
-
-
0033643217
-
Optimized synthesis of RNA-protein fusions for in vitro protein selection
-
Liu, R. H., Barrick, J. E., Szostak, J. W. & Roberts, R. W. Optimized synthesis of RNA-protein fusions for in vitro protein selection. Methods Enzymol. 318, 268-293 (2000).
-
(2000)
Methods Enzymol
, vol.318
, pp. 268-293
-
-
Liu, R.H.1
Barrick, J.E.2
Szostak, J.W.3
Roberts, R.W.4
-
35
-
-
0030779872
-
Mutational analysis of potential zinc-binding residues in the active site of the enterococcal D-Ala-D-Ala dipeptidase VanX
-
McCafferty, D. G., Lessard, I. A. D. & Walsh, C. T. Mutational analysis of potential zinc-binding residues in the active site of the enterococcal D-Ala-D-Ala dipeptidase VanX. Biochemistry 36, 10498-10505 (1997).
-
(1997)
Biochemistry
, vol.36
, pp. 10498-10505
-
-
McCafferty, D.G.1
Lessard, I.A.D.2
Walsh, C.T.3
-
36
-
-
84945505772
-
-
Hall, T. A. BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucl. Acids Symp. Ser. 41, 95-98 (1999).
-
Hall, T. A. BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucl. Acids Symp. Ser. 41, 95-98 (1999).
-
-
-
-
37
-
-
0024297354
-
Multiple sequence alignment with hierarchical-clustering
-
Corpet, F. Multiple sequence alignment with hierarchical-clustering. Nucleic Acids Res. 16, 10881-10890 (1988).
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 10881-10890
-
-
Corpet, F.1
|