Theoretical site-directed mutagenesis: Asp168Ala mutant of lactate dehydrogenase

Journal of the Royal Society Interface

Volumn 5, Issue SUPPL. 3, 2008, Pages

  Ferrer, Silvia ^a   Tuñón, Iñaki ^a   Moliner, Vicent ^b   Williams, Ian H ^c  

^a UNIVERSITY OF VALENCIA   (Spain)

^b UNIVERSITAT JAUME I   (Spain)

^c University of Bath   (United Kingdom)

Author keywords

Enzymatic catalysis; Lactate dehydrogenase; Quantum mechanics molecular mechanics

Indexed keywords

ENZYME ACTIVITY; MECHANICS; MOLECULAR MODELING; MOLECULES; POTENTIAL ENERGY; QUANTUM CHEMISTRY; QUANTUM THEORY; SURFACE REACTIONS;

% REDUCTIONS; ENZYMATIC CATALYSIS; ENZYMATIC REACTION; LACTATE DEHYDROGENASE; MOLECULAR MECHANICS METHOD; MOLECULAR SIMULATIONS; MUTANT ENZYMES; QUANTUM MECHANICS/MOLECULAR MECHANICS; SITE DIRECTED MUTAGENESIS; WILD TYPES;

CATALYSIS;

LACTATE DEHYDROGENASE;

ARTICLE; BIOLOGY; CHEMICAL STRUCTURE; COMPARATIVE STUDY; COMPUTER SIMULATION; GENETICS; METHODOLOGY; MISSENSE MUTATION; SITE DIRECTED MUTAGENESIS;

COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; L-LACTATE DEHYDROGENASE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE;

EID: 58749109635     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2008.0211.focus     Document Type: Article

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