Electrostatic contributions to protein-protein binding affinities: Application to Rap/Raf interaction

Proteins: Structure, Function and Genetics

Volumn 30, Issue 4, 1998, Pages 407-423

  Muegge, Ingo ^a,b   Schweins, Thomas ^a,c   Warshel, Arieh ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b ABBOTT LABORATORIES   (United States)

^c SANOFI   (France)

Author keywords

Binding free energy; Electrostatics; Group contributions; Solvation; Thermodynamic cycle

Indexed keywords

PROTEIN P21; RAF PROTEIN;

ARTICLE; BINDING AFFINITY; DIELECTRIC CONSTANT; DIPOLE; IONIZATION; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SOLVATION; THERMODYNAMICS;

COMPUTER SIMULATION; ELECTROSTATICS; GENE PRODUCTS, VPR; LIGANDS; MODELS, MOLECULAR; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-RAF; THERMODYNAMICS;

EID: 0032031405     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0134(19980301)30:4<407::AID-PROT8>3.0.CO;2-F     Document Type: Article

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