-
1
-
-
1642410886
-
Theoretical insights in enzyme catalysis
-
Marti, S., Roca, M., Andres, J., Moliner, V., Silla, E., Tunon, I., and Bertran, J. (2004) Theoretical insights in enzyme catalysis, Chem. Soc. Rev. 33, 98-107.
-
(2004)
Chem. Soc. Rev
, vol.33
, pp. 98-107
-
-
Marti, S.1
Roca, M.2
Andres, J.3
Moliner, V.4
Silla, E.5
Tunon, I.6
Bertran, J.7
-
2
-
-
33748633480
-
Electrostatic basis for enzyme catalysis
-
Warshel, A., Sharma, P. K., Kato, M., Xiang, Y., Liu, H. B., and Olsson, M. H. M. (2006) Electrostatic basis for enzyme catalysis, Chem. Rev. 106, 3210-3235.
-
(2006)
Chem. Rev
, vol.106
, pp. 3210-3235
-
-
Warshel, A.1
Sharma, P.K.2
Kato, M.3
Xiang, Y.4
Liu, H.B.5
Olsson, M.H.M.6
-
3
-
-
0029102089
-
Dynamics of the Dihydrofolate-Reductase Folate Complex: Catalytic Sites and Regions Known to Undergo Conformational Change Exhibit Diverse Dynamical Features
-
Epstein, D. M., Benkovic, S. J., and Wright, P. E. (1995) Dynamics of the Dihydrofolate-Reductase Folate Complex: Catalytic Sites and Regions Known to Undergo Conformational Change Exhibit Diverse Dynamical Features, Biochemistry 34, 11037-11048.
-
(1995)
Biochemistry
, vol.34
, pp. 11037-11048
-
-
Epstein, D.M.1
Benkovic, S.J.2
Wright, P.E.3
-
4
-
-
3042660150
-
Structure, dynamics, and catalytic function of dihydrofolate reductase
-
Schnell, J. R., Dyson, H. J., and Wright, P. E. (2004) Structure, dynamics, and catalytic function of dihydrofolate reductase, Annu. Rev. Biophys. Biomol. Struct. 33, 119-140.
-
(2004)
Annu. Rev. Biophys. Biomol. Struct
, vol.33
, pp. 119-140
-
-
Schnell, J.R.1
Dyson, H.J.2
Wright, P.E.3
-
5
-
-
1842839777
-
Quantum-classical simulation methods for hydrogen transfer in enzymes: A case study of dihydrofolate reductase
-
Hammes-Schiffer, S. (2004) Quantum-classical simulation methods for hydrogen transfer in enzymes: A case study of dihydrofolate reductase, Curr. Opin. Struct. Biol. 14, 192-201.
-
(2004)
Curr. Opin. Struct. Biol
, vol.14
, pp. 192-201
-
-
Hammes-Schiffer, S.1
-
6
-
-
33646935697
-
Dynamical contributions to enzyme catalysis: Critical tests of a popular hypothesis
-
Olsson, M. H. M., Parson, W. W., and Warshel, A. (2006) Dynamical contributions to enzyme catalysis: Critical tests of a popular hypothesis, Chem. Rev. 106, 1737-1756.
-
(2006)
Chem. Rev
, vol.106
, pp. 1737-1756
-
-
Olsson, M.H.M.1
Parson, W.W.2
Warshel, A.3
-
7
-
-
32244432145
-
Effects of a distal mutation on active site chemistry
-
Wang, L., Tharp, S., Selzer, T., Benkovic, S. J., and Kohen, A. (2006) Effects of a distal mutation on active site chemistry, Biochemistry 45, 1383-1392.
-
(2006)
Biochemistry
, vol.45
, pp. 1383-1392
-
-
Wang, L.1
Tharp, S.2
Selzer, T.3
Benkovic, S.J.4
Kohen, A.5
-
8
-
-
0032560505
-
Adjustment of conformational flexibility is a key event in the thermal adaptation of proteins
-
Zavodszky, P., Kardos, J., Svingor, A., and Petsko, G. A. (1998) Adjustment of conformational flexibility is a key event in the thermal adaptation of proteins, Proc. Natl. Acad. Sci. U.S.A. 95, 7406-7411.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A
, vol.95
, pp. 7406-7411
-
-
Zavodszky, P.1
Kardos, J.2
Svingor, A.3
Petsko, G.A.4
-
9
-
-
0033519504
-
Quantum enzymology: Tunnel vision
-
Ringe, D., and Petsko, G. A. (1999) Quantum enzymology: Tunnel vision, Nature 399, 417-418.
-
(1999)
Nature
, vol.399
, pp. 417-418
-
-
Ringe, D.1
Petsko, G.A.2
-
10
-
-
0033519723
-
Enzyme dynamics and hydrogen tunnelling in a thermophilic alcohol dehydrogenase
-
Kohen, A., Cannio, R., Bartolucci, S., and Klinman, J. P. (1999) Enzyme dynamics and hydrogen tunnelling in a thermophilic alcohol dehydrogenase, Nature 399, 496-499.
-
(1999)
Nature
, vol.399
, pp. 496-499
-
-
Kohen, A.1
Cannio, R.2
Bartolucci, S.3
Klinman, J.P.4
-
11
-
-
0034327617
-
Protein flexibility correlates with degree of hydrogen tunneling in thermophilic and mesophilic alcohol dehydrogenases
-
Kohen, A., and Klinman, J. P. (2000) Protein flexibility correlates with degree of hydrogen tunneling in thermophilic and mesophilic alcohol dehydrogenases, J. Am. Chem. Soc. 122, 10738-10739.
-
(2000)
J. Am. Chem. Soc
, vol.122
, pp. 10738-10739
-
-
Kohen, A.1
Klinman, J.P.2
-
12
-
-
0035707451
-
Dynamics of biochemical and biophysical reactions: Insight from computer simulations
-
Warshel, A., and Parson, W. W. (2001) Dynamics of biochemical and biophysical reactions: Insight from computer simulations, Q. Rev. Biophys. 34, 563-679.
-
(2001)
Q. Rev. Biophys
, vol.34
, pp. 563-679
-
-
Warshel, A.1
Parson, W.W.2
-
13
-
-
0041761262
-
Hydride transfer during catalysis by dihydrofolate reductase from Thermotoga maritima
-
Maglia, G., Javed, M. H., and Allemann, R. K. (2003) Hydride transfer during catalysis by dihydrofolate reductase from Thermotoga maritima, Biochem. J. 374, 529-535.
-
(2003)
Biochem. J
, vol.374
, pp. 529-535
-
-
Maglia, G.1
Javed, M.H.2
Allemann, R.K.3
-
14
-
-
0025182490
-
Extremely Thermostable D-Glyceraldehyde-3-Phosphate Dehydrogenase from the Eubacterium Thermotoga maritima
-
Wrba, A., Schweiger, A., Schultes, V., Jaenicke, R., and Zavodszky, P. (1990) Extremely Thermostable D-Glyceraldehyde-3-Phosphate Dehydrogenase from the Eubacterium Thermotoga maritima, Biochemistry 29, 7584-7592.
-
(1990)
Biochemistry
, vol.29
, pp. 7584-7592
-
-
Wrba, A.1
Schweiger, A.2
Schultes, V.3
Jaenicke, R.4
Zavodszky, P.5
-
16
-
-
0000230329
-
Energetics of Enzyme Catalysis
-
Warshel, A. (1978) Energetics of Enzyme Catalysis, Proc. Natl. Acad. Sci. U.S.A. 75, 5250-5254.
-
(1978)
Proc. Natl. Acad. Sci. U.S.A
, vol.75
, pp. 5250-5254
-
-
Warshel, A.1
-
18
-
-
0016610491
-
Computer-Simulation of Protein Folding
-
Levitt, M., and Warshel, A. (1975) Computer-Simulation of Protein Folding, Nature 253, 694-698.
-
(1975)
Nature
, vol.253
, pp. 694-698
-
-
Levitt, M.1
Warshel, A.2
-
19
-
-
0023449962
-
Spin-Glasses and the Statistical-Mechanics of Protein Folding
-
Bryngelson, J. D., and Wolynes, P. G. (1987) Spin-Glasses and the Statistical-Mechanics of Protein Folding, Proc. Natl. Acad. Sci. U.S.A. 84, 7524-7528.
-
(1987)
Proc. Natl. Acad. Sci. U.S.A
, vol.84
, pp. 7524-7528
-
-
Bryngelson, J.D.1
Wolynes, P.G.2
-
20
-
-
0026519315
-
A Lattice Model for Protein-Structure Prediction at Low Resolution
-
Hinds, D. A., and Levitt, M. (1992) A Lattice Model for Protein-Structure Prediction at Low Resolution, Proc. Natl. Acad. Sci. U.S.A. 89, 2536-2540.
-
(1992)
Proc. Natl. Acad. Sci. U.S.A
, vol.89
, pp. 2536-2540
-
-
Hinds, D.A.1
Levitt, M.2
-
21
-
-
0029670994
-
Conserved residues and the mechanism of protein folding
-
Shakhnovich, E., Abkevich, V., and Ptitsyn, O. (1996) Conserved residues and the mechanism of protein folding, Nature 379, 96-98.
-
(1996)
Nature
, vol.379
, pp. 96-98
-
-
Shakhnovich, E.1
Abkevich, V.2
Ptitsyn, O.3
-
22
-
-
0025370815
-
Dominant Forces in Protein Folding
-
Dill, K. A. (1990) Dominant Forces in Protein Folding, Biochemistry 29, 7133-7155.
-
(1990)
Biochemistry
, vol.29
, pp. 7133-7155
-
-
Dill, K.A.1
-
23
-
-
0030018099
-
Folding simulations and computer redesign of protein A three-helix bundle motifs
-
Olszewski, K. A., Kolinski, A., and Skolnick, J. (1996) Folding simulations and computer redesign of protein A three-helix bundle motifs, Proteins: Struct., Funct., Genet. 25, 286-299.
-
(1996)
Proteins: Struct., Funct., Genet
, vol.25
, pp. 286-299
-
-
Olszewski, K.A.1
Kolinski, A.2
Skolnick, J.3
-
24
-
-
22844456329
-
Using simplified protein representation as a reference potential for all-atom calculations of folding free energy
-
Fan, Z. Z., Hwang, J. K., and Warshel, A. (1999) Using simplified protein representation as a reference potential for all-atom calculations of folding free energy, Theor. Chem. Acc. 103, 77-80.
-
(1999)
Theor. Chem. Acc
, vol.103
, pp. 77-80
-
-
Fan, Z.Z.1
Hwang, J.K.2
Warshel, A.3
-
25
-
-
0000728542
-
Microscopic and Semimicroscopic Calculations of Electrostatic Energies in Proteins by the Polaris and Enzymix Programs
-
Lee, F. S., Chu, Z. T., and Warshel, A. (1993) Microscopic and Semimicroscopic Calculations of Electrostatic Energies in Proteins by the Polaris and Enzymix Programs, J. Comput. Chem. 14, 161-185.
-
(1993)
J. Comput. Chem
, vol.14
, pp. 161-185
-
-
Lee, F.S.1
Chu, Z.T.2
Warshel, A.3
-
26
-
-
37349125262
-
-
Chu, Z. T., Villa, J., Strajbl, M., Schutz, C. N., Shurki, A., and Warshel, A. (2006) MOLARIS, version α9.06, University of Southern California, Los Angeles.
-
Chu, Z. T., Villa, J., Strajbl, M., Schutz, C. N., Shurki, A., and Warshel, A. (2006) MOLARIS, version α9.06, University of Southern California, Los Angeles.
-
-
-
-
28
-
-
33846076119
-
Modeling electrostatic effects in proteins
-
Warshel, A., Sharma, P. K., Kato, M., and Parson, W. W. (2006) Modeling electrostatic effects in proteins, Biochim. Biophys. Acta 1764, 1647-1676.
-
(2006)
Biochim. Biophys. Acta
, vol.1764
, pp. 1647-1676
-
-
Warshel, A.1
Sharma, P.K.2
Kato, M.3
Parson, W.W.4
-
29
-
-
34247596467
-
Electrostatic contributions to protein stability and folding energy
-
Roca, M., Messer, B., and Warshel, A. (2007) Electrostatic contributions to protein stability and folding energy, FEBS Lett. 581, 2065-2071.
-
(2007)
FEBS Lett
, vol.581
, pp. 2065-2071
-
-
Roca, M.1
Messer, B.2
Warshel, A.3
-
30
-
-
0021480222
-
Macroscopic Models for Studies of Electrostatic Interactions in Proteins: Limitations and Applicability
-
Warshel, A., Russell, S. T., and Churg, A. K. (1984) Macroscopic Models for Studies of Electrostatic Interactions in Proteins: Limitations and Applicability, Proc. Natl. Acad. Sci. U.S.A. 81, 4785-4789.
-
(1984)
Proc. Natl. Acad. Sci. U.S.A
, vol.81
, pp. 4785-4789
-
-
Warshel, A.1
Russell, S.T.2
Churg, A.K.3
-
31
-
-
0021476470
-
Calculations of Electrostatic Interactions in Biological Systems and in Solutions
-
Warshel, A., and Russell, S. T. (1984) Calculations of Electrostatic Interactions in Biological Systems and in Solutions, Q. Rev. Biophys. 17, 283-422.
-
(1984)
Q. Rev. Biophys
, vol.17
, pp. 283-422
-
-
Warshel, A.1
Russell, S.T.2
-
32
-
-
0034652206
-
Transition-state structure as a unifying basis in protein-folding mechanisms: Contact order, chain topology, stability, and the extended nucleus mechanism
-
Fersht, A. R. (2000) Transition-state structure as a unifying basis in protein-folding mechanisms: Contact order, chain topology, stability, and the extended nucleus mechanism, Proc. Natl. Acad. Sci. U.S.A. 97, 1525-1529.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A
, vol.97
, pp. 1525-1529
-
-
Fersht, A.R.1
-
33
-
-
20444389830
-
Structural Genomics of Thermotoga maritima proteins shows that contact order is a major determinant of protein thermostability
-
Robinson-Rechavi, M., and Godzik, A. (2005) Structural Genomics of Thermotoga maritima proteins shows that contact order is a major determinant of protein thermostability, Structure 13, 857-860.
-
(2005)
Structure
, vol.13
, pp. 857-860
-
-
Robinson-Rechavi, M.1
Godzik, A.2
-
34
-
-
0037058992
-
Probing the folding free energy landscape of the src-SH3 protein domain
-
Shea, J. E., Onuchic, J. N., and Brooks, C. L. (2002) Probing the folding free energy landscape of the src-SH3 protein domain, Proc. Natl. Acad. Sci. U.S.A. 99, 16064-16068.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A
, vol.99
, pp. 16064-16068
-
-
Shea, J.E.1
Onuchic, J.N.2
Brooks, C.L.3
-
35
-
-
0007836334
-
Dynamics of Reactions in Polar-Solvents: Semi-Classical Trajectory Studies of Electron-Transfer and Proton-Transfer Reactions
-
Warshel, A. (1982) Dynamics of Reactions in Polar-Solvents: Semi-Classical Trajectory Studies of Electron-Transfer and Proton-Transfer Reactions, J. Phys. Chem. 86, 2218-2224.
-
(1982)
J. Phys. Chem
, vol.86
, pp. 2218-2224
-
-
Warshel, A.1
-
36
-
-
33845282688
-
Microscopic Examination of Free-Energy Relationships for Electron-Transfer in Polar-Solvents
-
Hwang, J. K., and Warshel, A. (1987) Microscopic Examination of Free-Energy Relationships for Electron-Transfer in Polar-Solvents, J. Am. Chem. Soc. 109, 715-720.
-
(1987)
J. Am. Chem. Soc
, vol.109
, pp. 715-720
-
-
Hwang, J.K.1
Warshel, A.2
-
37
-
-
4243810035
-
Simulation of Enzyme-Reactions Using Valence-Bond Force-Fields and Other Hybrid Quantum-Classical Approaches
-
Aqvist, J., and Warshel, A. (1993) Simulation of Enzyme-Reactions Using Valence-Bond Force-Fields and Other Hybrid Quantum-Classical Approaches, Chem. Rev. 93, 2523-2544.
-
(1993)
Chem. Rev
, vol.93
, pp. 2523-2544
-
-
Aqvist, J.1
Warshel, A.2
-
38
-
-
27544492154
-
Through the channel and around the channel: Validating and comparing microscopic approaches for the evaluation of free energy profiles for ion penetration through ion channels
-
Kato, M., and Warshel, A. (2005) Through the channel and around the channel: Validating and comparing microscopic approaches for the evaluation of free energy profiles for ion penetration through ion channels, J. Phys. Chem. B 109, 19516-19522.
-
(2005)
J. Phys. Chem. B
, vol.109
, pp. 19516-19522
-
-
Kato, M.1
Warshel, A.2
-
39
-
-
84962477148
-
Structure/function correlations of proteins using MM, QM/MM, and related approaches: Methods, concepts, pitfalls, and current progress
-
Shurki, A., and Warshel, A. (2003) Structure/function correlations of proteins using MM, QM/MM, and related approaches: Methods, concepts, pitfalls, and current progress, Adv. Protein Chem. 66, 249-313.
-
(2003)
Adv. Protein Chem
, vol.66
, pp. 249-313
-
-
Shurki, A.1
Warshel, A.2
-
40
-
-
0344391945
-
Reaction-path energetics and kinetics of the hydride transfer reaction catalyzed by dihydrofolate reductase
-
Garcia-Viloca, M., Truhlar, D. G., and Gao, J. L. (2003) Reaction-path energetics and kinetics of the hydride transfer reaction catalyzed by dihydrofolate reductase, Biochemistry 42, 13558-13575.
-
(2003)
Biochemistry
, vol.42
, pp. 13558-13575
-
-
Garcia-Viloca, M.1
Truhlar, D.G.2
Gao, J.L.3
-
41
-
-
25144458498
-
Conformational substates modulate hydride transfer in dihydrofolate reductase
-
Thorpe, I. F., and Brooks, C. L. (2005) Conformational substates modulate hydride transfer in dihydrofolate reductase, J. Am. Chem. Soc. 127, 12997-13006.
-
(2005)
J. Am. Chem. Soc
, vol.127
, pp. 12997-13006
-
-
Thorpe, I.F.1
Brooks, C.L.2
-
42
-
-
0033616094
-
Catalytic mechanism of dihydrofolate reductase enzyme. A combined quantum-mechanical/molecular- mechanical characterization of transition state structure for the hydride transfer step
-
Castillo, R., Andres, J., and Moliner, V. (1999) Catalytic mechanism of dihydrofolate reductase enzyme. A combined quantum-mechanical/molecular- mechanical characterization of transition state structure for the hydride transfer step, J. Am. Chem. Soc. 121, 12140-12147.
-
(1999)
J. Am. Chem. Soc
, vol.121
, pp. 12140-12147
-
-
Castillo, R.1
Andres, J.2
Moliner, V.3
-
43
-
-
0242391099
-
-
Cummins, P. L., and Gready, J. E. (2003) Computational methods for the study of enzymic reaction mechanisms. II. An overlapping mechanically embedded method for hybrid semi-empirical-QM/MM calculations, THEOCHEM 632, 247-257.
-
Cummins, P. L., and Gready, J. E. (2003) Computational methods for the study of enzymic reaction mechanisms. II. An overlapping mechanically embedded method for hybrid semi-empirical-QM/MM calculations, THEOCHEM 632, 247-257.
-
-
-
-
44
-
-
34249104188
-
The Catalytic Effect of Dihydrofolate Reductase and Its Mutants Is Determined by Reorganization Energies
-
Liu, H., and Warshel, A. (2007) The Catalytic Effect of Dihydrofolate Reductase and Its Mutants Is Determined by Reorganization Energies, Biochemistry 46, 6011-6025.
-
(2007)
Biochemistry
, vol.46
, pp. 6011-6025
-
-
Liu, H.1
Warshel, A.2
-
45
-
-
0041600218
-
Simulation of Free-Energy Relationships and Dynamics of Sn2 Reactions in Aqueous-Solution
-
Hwang, J. K., King, G., Creighton, S., and Warshel, A. (1988) Simulation of Free-Energy Relationships and Dynamics of Sn2 Reactions in Aqueous-Solution, J. Am. Chem. Soc. 110, 5297-5311.
-
(1988)
J. Am. Chem. Soc
, vol.110
, pp. 5297-5311
-
-
Hwang, J.K.1
King, G.2
Creighton, S.3
Warshel, A.4
-
46
-
-
36549094414
-
A Surface Constrained All-Atom Solvent Model for Effective Simulations of Polar Solutions
-
King, G., and Warshel, A. (1989) A Surface Constrained All-Atom Solvent Model for Effective Simulations of Polar Solutions, J. Chem. Phys. 91, 3647-3661.
-
(1989)
J. Chem. Phys
, vol.91
, pp. 3647-3661
-
-
King, G.1
Warshel, A.2
-
47
-
-
0000115003
-
A Local Reaction Field Method for Fast Evaluation of Long-Range Electrostatic Interactions in Molecular Simulations
-
Lee, F. S., and Warshel, A. (1992) A Local Reaction Field Method for Fast Evaluation of Long-Range Electrostatic Interactions in Molecular Simulations, J. Chem. Phys. 97, 3100-3107.
-
(1992)
J. Chem. Phys
, vol.97
, pp. 3100-3107
-
-
Lee, F.S.1
Warshel, A.2
-
48
-
-
0034737320
-
The crystal structure of dihydrofolate reductase from Thermotoga maritima: Molecular features of thermostability
-
Dams, T., Auerbach, G., Bader, G., Jacob, U., Ploom, T., Huber, R., and Jaenicke, R. (2000) The crystal structure of dihydrofolate reductase from Thermotoga maritima: Molecular features of thermostability, J. Mol. Biol. 297, 659-672.
-
(2000)
J. Mol. Biol
, vol.297
, pp. 659-672
-
-
Dams, T.1
Auerbach, G.2
Bader, G.3
Jacob, U.4
Ploom, T.5
Huber, R.6
Jaenicke, R.7
-
49
-
-
0031015737
-
Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: Crystallographic evidence
-
Sawaya, M. R., and Kraut, J. (1997) Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: Crystallographic evidence, Biochemistry 36, 586-603.
-
(1997)
Biochemistry
, vol.36
, pp. 586-603
-
-
Sawaya, M.R.1
Kraut, J.2
-
50
-
-
0033551438
-
Stability and folding of dihydrofolate reductase from the hyperthermophilic bacterium Thermotoga maritima
-
Dams, T., and Jaenicke, R. (1999) Stability and folding of dihydrofolate reductase from the hyperthermophilic bacterium Thermotoga maritima, Biochemistry 38, 9169-9178.
-
(1999)
Biochemistry
, vol.38
, pp. 9169-9178
-
-
Dams, T.1
Jaenicke, R.2
-
51
-
-
0034622508
-
Multistate equilibrium unfolding of Escherichia coli dihydrofolate reductase: Thermodynamic and spectroscopic description of the native, intermediate, and unfolded ensembles
-
Ionescu, R. M., Smith, V. F., O'Neill, J. C., and Matthews, C. R. (2000) Multistate equilibrium unfolding of Escherichia coli dihydrofolate reductase: Thermodynamic and spectroscopic description of the native, intermediate, and unfolded ensembles, Biochemistry 39, 9540-9550.
-
(2000)
Biochemistry
, vol.39
, pp. 9540-9550
-
-
Ionescu, R.M.1
Smith, V.F.2
O'Neill, J.C.3
Matthews, C.R.4
-
52
-
-
0031808658
-
Stretching exercises: Flexibility in dihydrofolate reductase catalysis
-
Miller, G. P., and Benkovic, S. J. (1998) Stretching exercises: Flexibility in dihydrofolate reductase catalysis, Chem. Biol. 5, R105-R113.
-
(1998)
Chem. Biol
, vol.5
-
-
Miller, G.P.1
Benkovic, S.J.2
-
53
-
-
0024445808
-
Dispersed Polaron Simulations of Electron Transfer in Photosynthetic Reaction Centers
-
Warshel, A., Chu, Z. T., and Parson, W. W. (1989) Dispersed Polaron Simulations of Electron Transfer in Photosynthetic Reaction Centers, Science 246, 112-116.
-
(1989)
Science
, vol.246
, pp. 112-116
-
-
Warshel, A.1
Chu, Z.T.2
Parson, W.W.3
-
54
-
-
0001604008
-
The Dynamics of the Primary Event in Rhodopsins Revisited
-
Warshel, A., Chu, Z. T., and Hwang, J. K. (1991) The Dynamics of the Primary Event in Rhodopsins Revisited, Chem. Phys. 158, 303-314.
-
(1991)
Chem. Phys
, vol.158
, pp. 303-314
-
-
Warshel, A.1
Chu, Z.T.2
Hwang, J.K.3
-
55
-
-
10744230827
-
Some like it cold: Biocatalysis at low temperatures
-
Georlette, D., Blaise, V., Collins, T., D'Amico, S., Gratia, E., Hoyoux, A., Marx, J. C., Sonan, G., Feller, G., and Gerday, C. (2004) Some like it cold: Biocatalysis at low temperatures, FEMS Microbiol. Rev. 28, 25-42.
-
(2004)
FEMS Microbiol. Rev
, vol.28
, pp. 25-42
-
-
Georlette, D.1
Blaise, V.2
Collins, T.3
D'Amico, S.4
Gratia, E.5
Hoyoux, A.6
Marx, J.C.7
Sonan, G.8
Feller, G.9
Gerday, C.10
-
56
-
-
23844458318
-
Increased flexibility as a strategy for cold adaptation: A comparative molecular dynamics study of cold- and warm-active uracil DNA glycosylase
-
Olufsen, M., Smalas, A. O., Moe, E., and Brandsdal, B. O. (2005) Increased flexibility as a strategy for cold adaptation: A comparative molecular dynamics study of cold- and warm-active uracil DNA glycosylase, J. Biol. Chem. 280, 18042-18048.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 18042-18048
-
-
Olufsen, M.1
Smalas, A.O.2
Moe, E.3
Brandsdal, B.O.4
-
57
-
-
33747756504
-
Flexibility and enzymatic cold-adaptation: A comparative molecular dynamics investigation of the elastase family
-
Papaleo, E., Riccardi, L., Villa, C., Fantucci, P., and De Gioia, L. (2006) Flexibility and enzymatic cold-adaptation: A comparative molecular dynamics investigation of the elastase family, Biochim. Biophys. Acta 1764, 1397-1406.
-
(2006)
Biochim. Biophys. Acta
, vol.1764
, pp. 1397-1406
-
-
Papaleo, E.1
Riccardi, L.2
Villa, C.3
Fantucci, P.4
De Gioia, L.5
-
58
-
-
0034710867
-
How important are entropic contributions to enzyme catalysis
-
Villa, J., Strajbl, M., Glennon, T. M., Sham, Y. Y., Chu, Z. T., and Warshel, A. (2000) How important are entropic contributions to enzyme catalysis, Proc. Natl. Acad. Sci. U.S.A. 97, 11899-11904.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A
, vol.97
, pp. 11899-11904
-
-
Villa, J.1
Strajbl, M.2
Glennon, T.M.3
Sham, Y.Y.4
Chu, Z.T.5
Warshel, A.6
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