A new paradigm for electrostatic catalysis of radical reactions in vitamin B12 enzymes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 23, 2007, Pages 9661-9666

  Sharma, Pankaz K ^a   Chu, Zhen T ^a   Olsson, Mats H M ^a   Warshel, Arieh ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Simulation of enzymatic reactions; Strain effect; Transition state stabilization

Indexed keywords

COBAMAMIDE; CYANOCOBALAMIN; MUTASE; PROTEIN; RIBOSE;

ARTICLE; CATALYSIS; ELECTRICITY; ENERGY TRANSFER; ENZYME ACTIVE SITE; ENZYME ACTIVITY; EVOLUTION; PRIORITY JOURNAL; QUANTUM MECHANICS; REACTION ANALYSIS; SIMULATION;

CATALYSIS; COBAMIDES; COMPUTER SIMULATION; ELECTROSTATICS; INTRAMOLECULAR TRANSFERASES; MODELS, MOLECULAR; MOLECULAR STRUCTURE;

EID: 34547457947     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0702238104     Document Type: Article

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