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Volumn 9, Issue 10, 2008, Pages 1010-1018

Role of ATP-binding cassette (ABC) transporters in interactions between natural products and drugs

Author keywords

Breast cancer resistance protein; Flavonoids; Food drug interactions; Multidrug resistance protein; Mycotoxins; P glycoprotein

Indexed keywords

3 INDOLEMETHANOL; ABC TRANSPORTER; AURANTIIN; CHRYSIN; CYCLOSPORIN A; DAUNORUBICIN; DEXTROMETHORPHAN; DIGOXIN; DILTIAZEM; DOXORUBICIN; ELACRIDAR; FELODIPINE; FLAVONOID; FUMONISIN B1; GALLIC ACID; HERBACEOUS AGENT; HUANG LIAN JIE DU TANG; MORIN; MYCOTOXIN; NATURAL PRODUCT; NIMODIPINE; QUERCETIN; RHODAMINE 123; TALINOLOL; TERFENADINE; TOPOTECAN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VERAPAMIL; VINCRISTINE; VITEXIN 2' O RHAMNOSIDE; ABCG2 PROTEIN, HUMAN; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 2; TUMOR PROTEIN;

EID: 62749188875     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920008786927776     Document Type: Review
Times cited : (52)

References (73)
  • 1
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman, M.M.; Pastan, I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu. Rev. Biochem., 1993, 62, 385-427.
    • (1993) Annu. Rev. Biochem , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 2
    • 0034926792 scopus 로고    scopus 로고
    • The multi-structural feature of the multidrug resistance gene product P-glycoprotein: Implications for its mechanism of action (hypothesis)
    • Zhang, J.T. The multi-structural feature of the multidrug resistance gene product P-glycoprotein: implications for its mechanism of action (hypothesis). Mol. Membr. Biol., 2001, 18(2), 145-152.
    • (2001) Mol. Membr. Biol , vol.18 , Issue.2 , pp. 145-152
    • Zhang, J.T.1
  • 3
    • 33947417310 scopus 로고    scopus 로고
    • Shedding light on drug transport: Structure and function of the P-glycoprotein multidrug transporter (ABCB1)
    • Sharom, F.J. Shedding light on drug transport: structure and function of the P-glycoprotein multidrug transporter (ABCB1). Biochem. Cell. Biol., 2006, 84(6), 979-992.
    • (2006) Biochem. Cell. Biol , vol.84 , Issue.6 , pp. 979-992
    • Sharom, F.J.1
  • 5
    • 11844301652 scopus 로고    scopus 로고
    • Effects of dietary chemopreventive phytochemicals on P-glycoprotein function
    • Nabekura, T.; Kamiyama, S.; Kitagawa, S. Effects of dietary chemopreventive phytochemicals on P-glycoprotein function. Biochem. Biophys. Res. Commun., 2005, 327(3), 866-870.
    • (2005) Biochem. Biophys. Res. Commun , vol.327 , Issue.3 , pp. 866-870
    • Nabekura, T.1    Kamiyama, S.2    Kitagawa, S.3
  • 6
    • 15944408721 scopus 로고    scopus 로고
    • Absorption of fumonisin B1 and aminopentol on an in vitro model of intestinal epithelium; the role of P-glycoprotein
    • De Angelis, I.; Frigge, G.; Raimondi, F.; Stammati, A.; Zucco, F.; Caloni, F. Absorption of fumonisin B1 and aminopentol on an in vitro model of intestinal epithelium; the role of P-glycoprotein. Toxicon., 2005, 45(3), 285-291.
    • (2005) Toxicon , vol.45 , Issue.3 , pp. 285-291
    • De Angelis, I.1    Frigge, G.2    Raimondi, F.3    Stammati, A.4    Zucco, F.5    Caloni, F.6
  • 7
    • 36248970069 scopus 로고    scopus 로고
    • Chinese herbs of Shenghe Powder reverse multidrug resistance of gastric carcinoma SGC-7901
    • Wang, J.; Xia, Y.; Wang, H.; Hou, Z. Chinese herbs of Shenghe Powder reverse multidrug resistance of gastric carcinoma SGC-7901. Integr. Cancer Ther., 2007, 6(4), 400-404.
    • (2007) Integr. Cancer Ther , vol.6 , Issue.4 , pp. 400-404
    • Wang, J.1    Xia, Y.2    Wang, H.3    Hou, Z.4
  • 8
    • 36849094927 scopus 로고    scopus 로고
    • In-vivo and in-vitro studies on the effect of Huang-Lian-Jie-Du-Tang on nimodipine transport across rat blood-brain barrier
    • Zhang, D.M.; He, Z.W.; Liu, X.D.; Li, Y.; Xie, L.; Wang, G.J.; Liu, L. In-vivo and in-vitro studies on the effect of Huang-Lian-Jie-Du-Tang on nimodipine transport across rat blood-brain barrier. J. Pharm. Pharmacol., 2007, 59(12), 1733-1738.
    • (2007) J. Pharm. Pharmacol , vol.59 , Issue.12 , pp. 1733-1738
    • Zhang, D.M.1    He, Z.W.2    Liu, X.D.3    Li, Y.4    Xie, L.5    Wang, G.J.6    Liu, L.7
  • 10
    • 34247257725 scopus 로고    scopus 로고
    • Polymethoxylated flavones and other phenolic derivates from citrus in their inhibitory effects on P-glycoprotein-mediated transport of talinolol in Caco-2 cells
    • Mertens-Talcott, S.U.; De Castro, W.V.; Manthey, J.A.; Derendorf, H.; Butterweck, V. Polymethoxylated flavones and other phenolic derivates from citrus in their inhibitory effects on P-glycoprotein-mediated transport of talinolol in Caco-2 cells. J. Agric. Food Chem., 2007, 55(7), 2563-2568.
    • (2007) J. Agric. Food Chem , vol.55 , Issue.7 , pp. 2563-2568
    • Mertens-Talcott, S.U.1    De Castro, W.V.2    Manthey, J.A.3    Derendorf, H.4    Butterweck, V.5
  • 11
    • 34548590341 scopus 로고    scopus 로고
    • Effects of various methoxyflavones on vincristine uptake and multidrug resistance to vincristine in P-gp-overexpressing K562/ADM cells
    • Ohtani, H.; Ikegawa, T.; Honda, Y.; Kohyama, N.; Morimoto, S.; Shoyama, Y.; Juichi, M.; Naito, M.; Tsuruo, T.; Sawada, Y. Effects of various methoxyflavones on vincristine uptake and multidrug resistance to vincristine in P-gp-overexpressing K562/ADM cells. Pharm. Res., 2007, 24(10), 1936-1943.
    • (2007) Pharm. Res , vol.24 , Issue.10 , pp. 1936-1943
    • Ohtani, H.1    Ikegawa, T.2    Honda, Y.3    Kohyama, N.4    Morimoto, S.5    Shoyama, Y.6    Juichi, M.7    Naito, M.8    Tsuruo, T.9    Sawada, Y.10
  • 13
    • 33644914487 scopus 로고    scopus 로고
    • Flavonoid-drug interactions: Effects of flavonoids on ABC transporters
    • Morris, M.E.; Zhang, S. Flavonoid-drug interactions: effects of flavonoids on ABC transporters. Life Sci., 2006, 78(18), 2116-2130.
    • (2006) Life Sci , vol.78 , Issue.18 , pp. 2116-2130
    • Morris, M.E.1    Zhang, S.2
  • 14
    • 0031581819 scopus 로고    scopus 로고
    • Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein
    • Shapiro, A.B.; Ling, V. Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein. Biochem. Pharmacol., 1997, 53(4), 587-596.
    • (1997) Biochem. Pharmacol , vol.53 , Issue.4 , pp. 587-596
    • Shapiro, A.B.1    Ling, V.2
  • 15
    • 0028172728 scopus 로고
    • Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells. Activation of P-glycoprotein as a putative mechanism
    • Critchfield, J.W.; Welsh, C.J.; Phang, J.M.; Yeh, G.C. Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells. Activation of P-glycoprotein as a putative mechanism. Biochem. Pharmacol., 1994, 48(7), 1437-1445.
    • (1994) Biochem. Pharmacol , vol.48 , Issue.7 , pp. 1437-1445
    • Critchfield, J.W.1    Welsh, C.J.2    Phang, J.M.3    Yeh, G.C.4
  • 16
    • 0031060647 scopus 로고    scopus 로고
    • Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein
    • Castro, A.F.; Altenberg, G.A. Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein. Biochem. Pharmacol., 1997, 53(1), 89-93.
    • (1997) Biochem. Pharmacol , vol.53 , Issue.1 , pp. 89-93
    • Castro, A.F.1    Altenberg, G.A.2
  • 17
    • 0037196568 scopus 로고    scopus 로고
    • Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols
    • Jodoin, J.; Demeule, M.; Beliveau, R. Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols. Biochim. Biophys. Acta, 2002, 1542(1-3), 149-159.
    • (2002) Biochim. Biophys. Acta , vol.1542 , Issue.1-3 , pp. 149-159
    • Jodoin, J.1    Demeule, M.2    Beliveau, R.3
  • 19
    • 0037371275 scopus 로고    scopus 로고
    • Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport
    • Zhang, S.; Morris, M.E. Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport. J. Pharmacol. Exp. Ther., 2003, 304(3), 1258-1267.
    • (2003) J. Pharmacol. Exp. Ther , vol.304 , Issue.3 , pp. 1258-1267
    • Zhang, S.1    Morris, M.E.2
  • 21
    • 0032865554 scopus 로고    scopus 로고
    • Inhibition of the CYP3A4-mediated metabolism and P-glycoprotein-mediated transport of the HIV-1 protease inhibitor saquinavir by grapefruit juice components
    • Eagling, V.A.; Profit, L.; Back, D.J. Inhibition of the CYP3A4-mediated metabolism and P-glycoprotein-mediated transport of the HIV-1 protease inhibitor saquinavir by grapefruit juice components. Br. J. Clin. Pharmacol., 1999, 48(4), 543-552.
    • (1999) Br. J. Clin. Pharmacol , vol.48 , Issue.4 , pp. 543-552
    • Eagling, V.A.1    Profit, L.2    Back, D.J.3
  • 22
    • 39849096862 scopus 로고    scopus 로고
    • Assessment of intestinal absorption of vitexin-2″-o-rhamnoside in hawthorn leaves flavonoids in rat using in situ and in vitro absorption models
    • Xu, Y.A.; Fan, G.; Gao, S.; Hong, Z. Assessment of intestinal absorption of vitexin-2″-o-rhamnoside in hawthorn leaves flavonoids in rat using in situ and in vitro absorption models. Drug Dev. Ind. Pharm., 2008, 34(2), 164-170.
    • (2008) Drug Dev. Ind. Pharm , vol.34 , Issue.2 , pp. 164-170
    • Xu, Y.A.1    Fan, G.2    Gao, S.3    Hong, Z.4
  • 23
    • 0035108539 scopus 로고    scopus 로고
    • Grapefruit juice enhances intestinal absorption of the P-glycoprotein substrate talinolol
    • Spahn-Langguth, H.; Langguth, P. Grapefruit juice enhances intestinal absorption of the P-glycoprotein substrate talinolol. Eur. J. Pharm. Sci., 2001, 12(4), 361-367.
    • (2001) Eur. J. Pharm. Sci , vol.12 , Issue.4 , pp. 361-367
    • Spahn-Langguth, H.1    Langguth, P.2
  • 24
    • 27644593975 scopus 로고    scopus 로고
    • Enhanced oral exposure of diltiazem by the concomitant use of naringin in rats
    • Choi, J.S.; Han, H.K. Enhanced oral exposure of diltiazem by the concomitant use of naringin in rats. Int. J. Pharm., 2005, 305(1-2), 122-128.
    • (2005) Int. J. Pharm , vol.305 , Issue.1-2 , pp. 122-128
    • Choi, J.S.1    Han, H.K.2
  • 26
    • 0037178587 scopus 로고    scopus 로고
    • The effect of grapefruit juice and seville orange juice on the pharmacokinetics of dextromethorphan: The role of gut CYP3A and P-glycoprotein
    • Di Marco, M.P.; Edwards, D.J.; Wainer, I.W.; Ducharme, M.P. The effect of grapefruit juice and seville orange juice on the pharmacokinetics of dextromethorphan: the role of gut CYP3A and P-glycoprotein. Life Sci., 2002, 71(10), 1149-1160.
    • (2002) Life Sci , vol.71 , Issue.10 , pp. 1149-1160
    • Di Marco, M.P.1    Edwards, D.J.2    Wainer, I.W.3    Ducharme, M.P.4
  • 27
    • 14044269476 scopus 로고    scopus 로고
    • Flavonoids chrysin and benzoflavone, potent breast cancer resistance protein inhibitors, have no significant effect on topotecan pharmacokinetics in rats or mdr1a/1b (-/-) mice
    • Zhang, S.; Wang, X.; Sagawa, K.; Morris, M.E. Flavonoids chrysin and benzoflavone, potent breast cancer resistance protein inhibitors, have no significant effect on topotecan pharmacokinetics in rats or mdr1a/1b (-/-) mice. Drug Metab. Dispos., 2005, 33(3), 341-348.
    • (2005) Drug Metab. Dispos , vol.33 , Issue.3 , pp. 341-348
    • Zhang, S.1    Wang, X.2    Sagawa, K.3    Morris, M.E.4
  • 29
    • 47349108866 scopus 로고    scopus 로고
    • Effect of grapefruit juice, naringin, naringenin, and bergamottin on the intestinal carrier-mediated transport of talinolol in rats
    • de Castro, W.V.; Mertens-Talcott, S.; Derendorf, H.; Butterweck, V. Effect of grapefruit juice, naringin, naringenin, and bergamottin on the intestinal carrier-mediated transport of talinolol in rats. J. Agric. Food Chem., 2008, 56(12), 4840-4845.
    • (2008) J. Agric. Food Chem , vol.56 , Issue.12 , pp. 4840-4845
    • de Castro, W.V.1    Mertens-Talcott, S.2    Derendorf, H.3    Butterweck, V.4
  • 30
    • 0034177453 scopus 로고    scopus 로고
    • Variance of common flavonoids by brand of grapefruit juice
    • Ross, S.A.; Ziska, D.S.; Zhao, K.; ElSohly, M.A. Variance of common flavonoids by brand of grapefruit juice. Fitoterapia, 2000, 71(2), 154-161.
    • (2000) Fitoterapia , vol.71 , Issue.2 , pp. 154-161
    • Ross, S.A.1    Ziska, D.S.2    Zhao, K.3    ElSohly, M.A.4
  • 31
    • 0030897505 scopus 로고    scopus 로고
    • Grapefruit juice-terfenadine single-dose interaction: Magnitude, mechanism, and relevance
    • Rau, S.E.; Bend, J.R.; Arnold, M.O.; Tran, L.T.; Spence, J.D.; Bailey, D.G. Grapefruit juice-terfenadine single-dose interaction: magnitude, mechanism, and relevance. Clin. Pharmacol. Ther., 1997, 61(4), 401-409.
    • (1997) Clin. Pharmacol. Ther , vol.61 , Issue.4 , pp. 401-409
    • Rau, S.E.1    Bend, J.R.2    Arnold, M.O.3    Tran, L.T.4    Spence, J.D.5    Bailey, D.G.6
  • 32
    • 0035021840 scopus 로고    scopus 로고
    • Influence of beta-adrenergic antagonists, H1-receptor blockers, analgesics, diuretics, and quinolone antibiotics on the cellular accumulation of the anticancer drug, daunorubicin: P-glycoprotein modulation
    • Ibrahim, S.; Peggins, J.; Knapton, A.; Licht, T.; Aszalos, A. Influence of beta-adrenergic antagonists, H1-receptor blockers, analgesics, diuretics, and quinolone antibiotics on the cellular accumulation of the anticancer drug, daunorubicin: P-glycoprotein modulation. Anticancer Res., 2001, 21(2A), 847-856.
    • (2001) Anticancer Res , vol.21 , Issue.2 A , pp. 847-856
    • Ibrahim, S.1    Peggins, J.2    Knapton, A.3    Licht, T.4    Aszalos, A.5
  • 33
    • 0031001463 scopus 로고    scopus 로고
    • Effects of grapefruit juice ingestion - pharmacokinetics and haemodynamics of intravenously and orally administered felodipine in healthy men
    • Lundahl, J.; Regardh, C.G.; Edgar, B.; Johnsson, G. Effects of grapefruit juice ingestion - pharmacokinetics and haemodynamics of intravenously and orally administered felodipine in healthy men. Eur. J. Clin. Pharmacol., 1997, 52(2), 139-145.
    • (1997) Eur. J. Clin. Pharmacol , vol.52 , Issue.2 , pp. 139-145
    • Lundahl, J.1    Regardh, C.G.2    Edgar, B.3    Johnsson, G.4
  • 34
    • 0029851370 scopus 로고    scopus 로고
    • Effect of grapefruit juice on the pharmacokinetics of amlodipine in healthy volunteers
    • Josefsson, M.; Zackrisson, A.L.; Ahlner, J. Effect of grapefruit juice on the pharmacokinetics of amlodipine in healthy volunteers. Eur. J. Clin. Pharmacol., 1996, 51(2), 189-193.
    • (1996) Eur. J. Clin. Pharmacol , vol.51 , Issue.2 , pp. 189-193
    • Josefsson, M.1    Zackrisson, A.L.2    Ahlner, J.3
  • 35
    • 33745256217 scopus 로고    scopus 로고
    • Interaction of grapefruit juice and calcium channel blockers
    • Sica, D.A. Interaction of grapefruit juice and calcium channel blockers. Am. J. Hypertens., 2006, 19(7), 768-773.
    • (2006) Am. J. Hypertens , vol.19 , Issue.7 , pp. 768-773
    • Sica, D.A.1
  • 37
    • 0031954328 scopus 로고    scopus 로고
    • Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid
    • Kantola, T.; Kivisto, K.T.; Neuvonen, P.J. Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid. Clin. Pharmacol. Ther., 1998, 63(4), 397-402.
    • (1998) Clin. Pharmacol. Ther , vol.63 , Issue.4 , pp. 397-402
    • Kantola, T.1    Kivisto, K.T.2    Neuvonen, P.J.3
  • 38
    • 0031741901 scopus 로고    scopus 로고
    • Grapefruit juice-simvastatin interaction: Effect on serum concentrations of simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors
    • Lilja, J.J.; Kivisto, K.T.; Neuvonen, P.J. Grapefruit juice-simvastatin interaction: effect on serum concentrations of simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors. Clin. Pharmacol. Ther., 1998, 64(5), 477-483.
    • (1998) Clin. Pharmacol. Ther , vol.64 , Issue.5 , pp. 477-483
    • Lilja, J.J.1    Kivisto, K.T.2    Neuvonen, P.J.3
  • 39
    • 0027155665 scopus 로고
    • Grapefruit juice - felodipine interaction: Mechanism, predictability, and effect of naringin
    • Bailey, D.G.; Arnold, J.M.; Munoz, C.; Spence, J.D. Grapefruit juice - felodipine interaction: mechanism, predictability, and effect of naringin. Clin. Pharmacol. Ther., 1993, 53(6), 637-642.
    • (1993) Clin. Pharmacol. Ther , vol.53 , Issue.6 , pp. 637-642
    • Bailey, D.G.1    Arnold, J.M.2    Munoz, C.3    Spence, J.D.4
  • 40
    • 0029055363 scopus 로고
    • Disposition of intravenous and oral cyclosporine after administration with grapefruit juice
    • Ducharme, M.P.; Warbasse, L.H.; Edwards, D.J. Disposition of intravenous and oral cyclosporine after administration with grapefruit juice. Clin. Pharmacol. Ther., 1995, 57(5), 485-491.
    • (1995) Clin. Pharmacol. Ther , vol.57 , Issue.5 , pp. 485-491
    • Ducharme, M.P.1    Warbasse, L.H.2    Edwards, D.J.3
  • 42
    • 37349113752 scopus 로고    scopus 로고
    • Medicinal importance of grapefruit juice and its interaction with various drugs
    • Kiani, J.; Imam, S.Z. Medicinal importance of grapefruit juice and its interaction with various drugs. Nutr. J., 2007, 6, 33.
    • (2007) Nutr. J , vol.6 , pp. 33
    • Kiani, J.1    Imam, S.Z.2
  • 43
    • 0034674901 scopus 로고    scopus 로고
    • A family of drug transporters: The multidrug resistance-associated proteins
    • Borst, P.; Evers, R.; Kool, M.; Wijnholds, J. A family of drug transporters: the multidrug resistance-associated proteins. J. Natl. Cancer Inst., 2000, 92(16), 1295-1302.
    • (2000) J. Natl. Cancer Inst , vol.92 , Issue.16 , pp. 1295-1302
    • Borst, P.1    Evers, R.2    Kool, M.3    Wijnholds, J.4
  • 44
    • 0035033774 scopus 로고    scopus 로고
    • Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids
    • Leslie, E.M.; Mao, Q.; Oleschuk, C.J.; Deeley, R.G.; Cole, S.P. Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids. Mol. Pharmacol., 2001, 59(5), 1171-1180.
    • (2001) Mol. Pharmacol , vol.59 , Issue.5 , pp. 1171-1180
    • Leslie, E.M.1    Mao, Q.2    Oleschuk, C.J.3    Deeley, R.G.4    Cole, S.P.5
  • 45
    • 0037311322 scopus 로고    scopus 로고
    • Effect of flavonoids on MRP1-mediated transport in Panc-1 cells
    • Nguyen, H.; Zhang, S.; Morris, M.E. Effect of flavonoids on MRP1-mediated transport in Panc-1 cells. J. Pharm. Sci., 2003, 92(2), 250-257.
    • (2003) J. Pharm. Sci , vol.92 , Issue.2 , pp. 250-257
    • Nguyen, H.1    Zhang, S.2    Morris, M.E.3
  • 46
    • 12744256734 scopus 로고    scopus 로고
    • Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2
    • van Zanden, J.J.; Wortelboer, H.M.; Bijlsma, S.; Punt, A.; Usta, M.; Bladeren, P.J.; Rietjens, I.M.; Cnubben, N.H. Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2. Biochem. Pharmacol., 2005, 69(4), 699-708.
    • (2005) Biochem. Pharmacol , vol.69 , Issue.4 , pp. 699-708
    • van Zanden, J.J.1    Wortelboer, H.M.2    Bijlsma, S.3    Punt, A.4    Usta, M.5    Bladeren, P.J.6    Rietjens, I.M.7    Cnubben, N.H.8
  • 47
    • 0035813012 scopus 로고    scopus 로고
    • Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters
    • Leslie, E.M.; Deeley, R.G.; Cole, S.P. Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters. Toxicology, 2001, 167(1), 3-23.
    • (2001) Toxicology , vol.167 , Issue.1 , pp. 3-23
    • Leslie, E.M.1    Deeley, R.G.2    Cole, S.P.3
  • 48
    • 0344927562 scopus 로고    scopus 로고
    • Conjugate export pumps of the multidrug resistance protein (MRP) family: Localization, substrate specificity, and MRP2-mediated drug resistance
    • Konig, J.; Nies, A.T.; Cui, Y.; Leier, I.; Keppler, D. Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance. Biochim. Biophys. Acta, 1999, 1461(2), 377-394.
    • (1999) Biochim. Biophys. Acta , vol.1461 , Issue.2 , pp. 377-394
    • Konig, J.1    Nies, A.T.2    Cui, Y.3    Leier, I.4    Keppler, D.5
  • 49
    • 0141456201 scopus 로고    scopus 로고
    • Biliary excretion of flavopiridol and its glucuronides in the isolated perfused rat liver: Role of multidrug resistance protein 2 (Mrp2)
    • Jager, W.; Gehring, E.; Hagenauer, B.; Aust, S.; Senderowicz, A.; Thalhammer, T. Biliary excretion of flavopiridol and its glucuronides in the isolated perfused rat liver: role of multidrug resistance protein 2 (Mrp2). Life Sci., 2003, 73(22), 2841-2854.
    • (2003) Life Sci , vol.73 , Issue.22 , pp. 2841-2854
    • Jager, W.1    Gehring, E.2    Hagenauer, B.3    Aust, S.4    Senderowicz, A.5    Thalhammer, T.6
  • 52
    • 34547810884 scopus 로고    scopus 로고
    • Epithelial transport of deoxynivalenol: Involvement of human P-glycoprotein (ABCB1) and multidrug resistance-associated protein 2 (ABCC2)
    • Videmann, B.; Tep, J.; Cavret, S.; Lecoeur, S. Epithelial transport of deoxynivalenol: involvement of human P-glycoprotein (ABCB1) and multidrug resistance-associated protein 2 (ABCC2). Food Chem. Toxicol., 2007, 45(10), 1938-1947.
    • (2007) Food Chem. Toxicol , vol.45 , Issue.10 , pp. 1938-1947
    • Videmann, B.1    Tep, J.2    Cavret, S.3    Lecoeur, S.4
  • 55
    • 0038235715 scopus 로고    scopus 로고
    • Lack of de-epoxidation of type B trichothecenes in incubates with human faeces
    • Sundstol Eriksen, G.; Pettersson, H. Lack of de-epoxidation of type B trichothecenes in incubates with human faeces. Food Addit. Contam., 2003, 20(6), 579-582.
    • (2003) Food Addit. Contam , vol.20 , Issue.6 , pp. 579-582
    • Sundstol Eriksen, G.1    Pettersson, H.2
  • 56
    • 0037432669 scopus 로고    scopus 로고
    • Interaction of ochratoxin A with human intestinal Caco-2 cells: Possible implication of a multidrug resistance-associated protein (MRP2)
    • Berger, V.; Gabriel, A.F.; Sergent, T.; Trouet, A.; Larondelle, Y.; Schneider, Y.J. Interaction of ochratoxin A with human intestinal Caco-2 cells: possible implication of a multidrug resistance-associated protein (MRP2). Toxicol. Lett., 2003, 140-141, 465-476.
    • (2003) Toxicol. Lett , vol.140-141 , pp. 465-476
    • Berger, V.1    Gabriel, A.F.2    Sergent, T.3    Trouet, A.4    Larondelle, Y.5    Schneider, Y.J.6
  • 57
    • 0038265441 scopus 로고    scopus 로고
    • ABCG2 transports sulfated conjugates of steroids and xenobiotics
    • Suzuki, M.; Suzuki, H.; Sugimoto, Y.; Sugiyama, Y. ABCG2 transports sulfated conjugates of steroids and xenobiotics. J. Biol. Chem., 2003, 278(25), 22644-22649.
    • (2003) J. Biol. Chem , vol.278 , Issue.25 , pp. 22644-22649
    • Suzuki, M.1    Suzuki, H.2    Sugimoto, Y.3    Sugiyama, Y.4
  • 58
    • 0034234653 scopus 로고    scopus 로고
    • Expression of breast cancer resistance protein in blast cells from patients with acute leukemia
    • Ross, D.D.; Karp, J.E.; Chen, T.T.; Doyle, L.A. Expression of breast cancer resistance protein in blast cells from patients with acute leukemia. Blood, 2000, 96(1), 365-368.
    • (2000) Blood , vol.96 , Issue.1 , pp. 365-368
    • Ross, D.D.1    Karp, J.E.2    Chen, T.T.3    Doyle, L.A.4
  • 59
    • 0037113346 scopus 로고    scopus 로고
    • Localisation of breast cancer resistance protein in microvessel endothelium of human brain
    • Cooray, H.C.; Blackmore, C.G.; Maskell, L.; Barrand, M.A. Localisation of breast cancer resistance protein in microvessel endothelium of human brain. Neuroreport, 2002, 13(16), 2059-2063.
    • (2002) Neuroreport , vol.13 , Issue.16 , pp. 2059-2063
    • Cooray, H.C.1    Blackmore, C.G.2    Maskell, L.3    Barrand, M.A.4
  • 62
    • 0034811602 scopus 로고    scopus 로고
    • Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers
    • Taipalensuu, J.; Tornblom, H.; Lindberg, G.; Einarsson, C.; Sjoqvist, F.; Melhus, H.; Garberg, P.; Sjostrom, B.; Lundgren, B.; Artursson, P. Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers. J. Pharmacol. Exp. Ther., 2001, 299(1), 164-170.
    • (2001) J. Pharmacol. Exp. Ther , vol.299 , Issue.1 , pp. 164-170
    • Taipalensuu, J.1    Tornblom, H.2    Lindberg, G.3    Einarsson, C.4    Sjoqvist, F.5    Melhus, H.6    Garberg, P.7    Sjostrom, B.8    Lundgren, B.9    Artursson, P.10
  • 63
    • 2142711101 scopus 로고    scopus 로고
    • Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport
    • Zhang, S.; Yang, X.; Morris, M.E. Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport. Mol. Pharmacol., 2004, 65(5), 1208-1216.
    • (2004) Mol. Pharmacol , vol.65 , Issue.5 , pp. 1208-1216
    • Zhang, S.1    Yang, X.2    Morris, M.E.3
  • 64
    • 3042569646 scopus 로고    scopus 로고
    • Phytoestrogens/ flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance
    • Imai, Y.; Tsukahara, S.; Asada, S.; Sugimoto, Y. Phytoestrogens/ flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance. Cancer Res., 2004, 64(12), 4346-4352.
    • (2004) Cancer Res , vol.64 , Issue.12 , pp. 4346-4352
    • Imai, Y.1    Tsukahara, S.2    Asada, S.3    Sugimoto, Y.4
  • 67
    • 17644382339 scopus 로고    scopus 로고
    • Effect of organic isothiocyanates on breast cancer resistance protein (ABCG2)-mediated transport
    • Ji, Y.; Morris, M.E. Effect of organic isothiocyanates on breast cancer resistance protein (ABCG2)-mediated transport. Pharm. Res., 2004, 21(12), 2261-2269.
    • (2004) Pharm. Res , vol.21 , Issue.12 , pp. 2261-2269
    • Ji, Y.1    Morris, M.E.2
  • 68
    • 35148834736 scopus 로고    scopus 로고
    • Drug-drug interactions affected by the transporter protein, P-glycoprotein (ABCB1, MDR1) II. Clinical aspects
    • Aszalos, A. Drug-drug interactions affected by the transporter protein, P-glycoprotein (ABCB1, MDR1) II. Clinical aspects. Drug Discov. Today, 2007, 12(19-20), 838-843.
    • (2007) Drug Discov. Today , vol.12 , Issue.19-20 , pp. 838-843
    • Aszalos, A.1
  • 69
    • 33750353446 scopus 로고    scopus 로고
    • Flavonoid-mediated inhibition of intestinal ABC transporters may affect the oral bioavailability of drugs, food-borne toxic compounds and bioactive ingredients
    • Brand, W.; Schutte, M.E.; Williamson, G.; van Zanden, J.J.; Cnubben, N.H.; Groten, J.P.; van Bladeren, P.J.; Rietjens, I.M. Flavonoid-mediated inhibition of intestinal ABC transporters may affect the oral bioavailability of drugs, food-borne toxic compounds and bioactive ingredients. Biomed. Pharmacother., 2006, 60(9), 508-519.
    • (2006) Biomed. Pharmacother , vol.60 , Issue.9 , pp. 508-519
    • Brand, W.1    Schutte, M.E.2    Williamson, G.3    van Zanden, J.J.4    Cnubben, N.H.5    Groten, J.P.6    van Bladeren, P.J.7    Rietjens, I.M.8
  • 72
    • 33947420519 scopus 로고    scopus 로고
    • Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice
    • Bailey, D.G.; Dresser, G.K.; Leake, B.F.; Kim, R.B. Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice. Clin. Pharmacol. Ther., 2007, 81(4), 495-502.
    • (2007) Clin. Pharmacol. Ther , vol.81 , Issue.4 , pp. 495-502
    • Bailey, D.G.1    Dresser, G.K.2    Leake, B.F.3    Kim, R.B.4
  • 73
    • 0036159433 scopus 로고    scopus 로고
    • Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine
    • Dresser, G.K.; Bailey, D.G.; Leake, B.F.; Schwarz, U.I.; Dawson, P.A.; Freeman, D.J.; Kim, R.B. Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine. Clin. Pharmacol. Ther., 2002, 71(1), 11-20.
    • (2002) Clin. Pharmacol. Ther , vol.71 , Issue.1 , pp. 11-20
    • Dresser, G.K.1    Bailey, D.G.2    Leake, B.F.3    Schwarz, U.I.4    Dawson, P.A.5    Freeman, D.J.6    Kim, R.B.7


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