Polymethoxylated flavones and other phenolic derivates from citrus in their inhibitory effects on P-glycoprotein-mediated transport of talinolol in Caco-2 cells

Journal of Agricultural and Food Chemistry

Volumn 55, Issue 7, 2007, Pages 2563-2568

  Mertens Talcott, Susanne U ^a   De Castro, Whocely Victor ^b   Manthey, John A ^b   Derendorf, Hartmut ^b   Butterweck, Veronika ^b  

^a UNIVERSITY OF FLORIDA HEALTH   (United States)

^b AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

Coumarins; Drug transport; Grapefruit drug interaction; P glycoprotein; Polymethoxylated flavones (PMF)

Indexed keywords

FLAVONE DERIVATIVE; GLYCOPROTEIN P; PHENOL DERIVATIVE; PROPANOLAMINE DERIVATIVE; TALINOLOL;

ARTICLE; CELL STRAIN CACO 2; CHEMISTRY; CITRUS FRUIT; DRUG ANTAGONISM; HUMAN; METABOLISM; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

BIOLOGICAL TRANSPORT; CACO-2 CELLS; CITRUS; FLAVONES; HUMANS; P-GLYCOPROTEIN; PHENOLS; PROPANOLAMINES;

CITRUS; CITRUS X PARADISI;

EID: 34247257725     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf063138v     Document Type: Article

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