-
1
-
-
0037451929
-
The epidemiology of sepsis in the United States from 1979 through 2000
-
10.1056/NEJMoa022139
-
GS Martin DM Mannino S Eaton M Moss 2003 The epidemiology of sepsis in the United States from 1979 through 2000 N Engl J Med 348 1546 1554 10.1056/NEJMoa022139
-
(2003)
N Engl J Med
, vol.348
, pp. 1546-1554
-
-
Martin, G.S.1
Mannino, D.M.2
Eaton, S.3
Moss, M.4
-
2
-
-
0026710191
-
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. the ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine
-
10.1378/chest.101.6.1644
-
RC Bone RA Balk FB Cerra 1992 Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine Chest 101 1644 1655 10.1378/chest.101.6.1644
-
(1992)
Chest
, vol.101
, pp. 1644-1655
-
-
Bone, R.C.1
Balk, R.A.2
Cerra, F.B.3
-
3
-
-
0037426726
-
The pathophysiology and treatment of sepsis
-
10.1056/NEJMra021333
-
RS Hotchkiss IE Karl 2003 The pathophysiology and treatment of sepsis N Engl J Med 348 138 150 10.1056/NEJMra021333
-
(2003)
N Engl J Med
, vol.348
, pp. 138-150
-
-
Hotchkiss, R.S.1
Karl, I.E.2
-
4
-
-
0030843156
-
Sepsis: A new hypothesis for pathogenesis of the disease process
-
10.1378/chest.112.1.235
-
RC Bone CJ Grodzin RA Balk 1997 Sepsis: a new hypothesis for pathogenesis of the disease process Chest 112 235 243 10.1378/chest.112.1.235
-
(1997)
Chest
, vol.112
, pp. 235-243
-
-
Bone, R.C.1
Grodzin, C.J.2
Balk, R.A.3
-
5
-
-
0029903114
-
Sir Isaac Newton, sepsis, SIRS, and CARS
-
10.1097/00003246-199607000-00010
-
RC Bone 1996 Sir Isaac Newton, sepsis, SIRS, and CARS Crit Care Med 24 1125 1128 10.1097/00003246-199607000-00010
-
(1996)
Crit Care Med
, vol.24
, pp. 1125-1128
-
-
Bone, R.C.1
-
6
-
-
34548159807
-
Mitochondria, endoplasmic reticulum, and alternative pathways of cell death in critical illness
-
10.1097/01.CCM.0000278045.91575.30
-
S Yasuhara A Asai ND Sahani JA Martyn 2007 Mitochondria, endoplasmic reticulum, and alternative pathways of cell death in critical illness Crit Care Med 35 S488 S495 10.1097/01.CCM.0000278045.91575.30
-
(2007)
Crit Care Med
, vol.35
-
-
Yasuhara, S.1
Asai, A.2
Sahani, N.D.3
Martyn, J.A.4
-
7
-
-
4544352237
-
Cell biology: Regulated self-cannibalism
-
10.1038/431031a
-
DJ Klionsky 2004 Cell biology: regulated self-cannibalism Nature 431 31 32 10.1038/431031a
-
(2004)
Nature
, vol.431
, pp. 31-32
-
-
Klionsky, D.J.1
-
8
-
-
4344583901
-
Role of mitochondrial permeability transition pores in mitochondrial autophagy
-
10.1016/j.biocel.2004.04.009
-
S Rodriguez-Enriquez L He JJ Lemasters 2004 Role of mitochondrial permeability transition pores in mitochondrial autophagy Int J Biochem Cell Biol 36 2463 2472 10.1016/j.biocel.2004.04.009
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 2463-2472
-
-
Rodriguez-Enriquez, S.1
He, L.2
Lemasters, J.J.3
-
9
-
-
41749104586
-
The inflammatory response to cell death
-
10.1146/annurev.pathmechdis.3.121806.151456
-
KL Rock H Kono 2008 The inflammatory response to cell death Annu Rev Pathol 3 99 126 10.1146/annurev.pathmechdis.3.121806.151456
-
(2008)
Annu Rev Pathol
, vol.3
, pp. 99-126
-
-
Rock, K.L.1
Kono, H.2
-
10
-
-
0037062934
-
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
-
10.1038/nature00858
-
P Scaffidi T Misteli ME Bianchi 2002 Release of chromatin protein HMGB1 by necrotic cells triggers inflammation Nature 418 191 195 10.1038/nature00858
-
(2002)
Nature
, vol.418
, pp. 191-195
-
-
Scaffidi, P.1
Misteli, T.2
Bianchi, M.E.3
-
11
-
-
34447116244
-
Identification of a key pathway required for the sterile inflammatory response triggered by dying cells
-
10.1038/nm1603
-
CJ Chen H Kono D Golenbock G Reed S Akira KL Rock 2007 Identification of a key pathway required for the sterile inflammatory response triggered by dying cells Nat Med 13 851 856 10.1038/nm1603
-
(2007)
Nat Med
, vol.13
, pp. 851-856
-
-
Chen, C.J.1
Kono, H.2
Golenbock, D.3
Reed, G.4
Akira, S.5
Rock, K.L.6
-
12
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
10.1038/nature04516
-
F Martinon V Petrilli A Mayor A Tardivel J Tschopp 2006 Gout-associated uric acid crystals activate the NALP3 inflammasome Nature 440 237 241 10.1038/nature04516
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
13
-
-
0026749874
-
Nucleosomes and DNA bind to specific cell-surface molecules on murine cells and induce cytokine production
-
10.1016/0090-1229(92)90229-H
-
SH Hefeneider KA Cornell LE Brown AC Bakke SL McCoy RM Bennett 1992 Nucleosomes and DNA bind to specific cell-surface molecules on murine cells and induce cytokine production Clin Immunol Immunopathol 63 245 251 10.1016/0090-1229(92)90229-H
-
(1992)
Clin Immunol Immunopathol
, vol.63
, pp. 245-251
-
-
Hefeneider, S.H.1
Cornell, K.A.2
Brown, L.E.3
Bakke, A.C.4
McCoy, S.L.5
Bennett, R.M.6
-
14
-
-
1942545081
-
Cytokine function of heat shock proteins
-
10.1152/ajpcell.00364.2003
-
MF Tsan B Gao 2004 Cytokine function of heat shock proteins Am J Physiol Cell Physiol 286 C739 C744 10.1152/ajpcell.00364.2003
-
(2004)
Am J Physiol Cell Physiol
, vol.286
-
-
Tsan, M.F.1
Gao, B.2
-
16
-
-
0842326097
-
Cathelicidins, multifunctional peptides of the innate immunity
-
10.1189/jlb.0403147
-
M Zanetti 2004 Cathelicidins, multifunctional peptides of the innate immunity J Leukoc Biol 75 39 48 10.1189/jlb.0403147
-
(2004)
J Leukoc Biol
, vol.75
, pp. 39-48
-
-
Zanetti, M.1
-
17
-
-
33845890803
-
Inflammasome adaptors and sensors: Intracellular regulators of infection and inflammation
-
10.1038/nri1997
-
S Mariathasan DM Monack 2007 Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation Nat Rev Immunol 7 31 40 10.1038/nri1997
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 31-40
-
-
Mariathasan, S.1
Monack, D.M.2
-
18
-
-
58149149839
-
TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events
-
10.1084/jem.20081370
-
KA Cavassani M Ishii H Wen 2008 TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events J Exp Med 205 2609 2621 10.1084/jem.20081370
-
(2008)
J Exp Med
, vol.205
, pp. 2609-2621
-
-
Cavassani, K.A.1
Ishii, M.2
Wen, H.3
-
19
-
-
52549125928
-
Mincle is an ITAM-coupled activating receptor that senses damaged cells
-
10.1038/ni.1651
-
S Yamasaki E Ishikawa M Sakuma H Hara K Ogata T Saito 2008 Mincle is an ITAM-coupled activating receptor that senses damaged cells Nat Immunol 9 1179 1188 10.1038/ni.1651
-
(2008)
Nat Immunol
, vol.9
, pp. 1179-1188
-
-
Yamasaki, S.1
Ishikawa, E.2
Sakuma, M.3
Hara, H.4
Ogata, K.5
Saito, T.6
-
20
-
-
0032575750
-
Caspases: Enemies within
-
10.1126/science.281.5381.1312
-
NA Thornberry Y Lazebnik 1998 Caspases: enemies within Science 281 1312 1316 10.1126/science.281.5381.1312
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
21
-
-
33745096533
-
Apoptosis effector mechanisms: A requiem performed in different keys
-
10.1007/s10495-006-6712-8
-
N Hail Jr BZ Carter M Konopleva M Andreeff 2006 Apoptosis effector mechanisms: a requiem performed in different keys Apoptosis 11 889 904 10.1007/s10495-006-6712-8
-
(2006)
Apoptosis
, vol.11
, pp. 889-904
-
-
Hail Jr, N.1
Carter, B.Z.2
Konopleva, M.3
Andreeff, M.4
-
22
-
-
0034641918
-
The biochemistry of apoptosis
-
10.1038/35037710
-
MO Hengartner 2000 The biochemistry of apoptosis Nature 407 770 776 10.1038/35037710
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
24
-
-
34249893895
-
Protease signalling in cell death: Caspases versus cysteine cathepsins
-
10.1016/j.febslet.2007.05.038
-
B Turk V Stoka 2007 Protease signalling in cell death: caspases versus cysteine cathepsins FEBS Lett 581 2761 2767 10.1016/j.febslet.2007.05.038
-
(2007)
FEBS Lett
, vol.581
, pp. 2761-2767
-
-
Turk, B.1
Stoka, V.2
-
25
-
-
0032575714
-
Death receptors: Signaling and modulation
-
10.1126/science.281.5381.1305
-
A Ashkenazi VM Dixit 1998 Death receptors: signaling and modulation Science 281 1305 1308 10.1126/science.281.5381.1305
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
26
-
-
5644222552
-
Life and death decisions: Secondary complexes and lipid rafts in TNF receptor family signal transduction
-
10.1016/j.immuni.2004.10.001
-
JR Muppidi J Tschopp RM Siegel 2004 Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction Immunity 21 461 465 10.1016/j.immuni.2004.10.001
-
(2004)
Immunity
, vol.21
, pp. 461-465
-
-
Muppidi, J.R.1
Tschopp, J.2
Siegel, R.M.3
-
27
-
-
5244224827
-
X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death
-
10.1038/381335a0
-
SW Muchmore M Sattler H Liang 1996 X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death Nature 381 335 341 10.1038/381335a0
-
(1996)
Nature
, vol.381
, pp. 335-341
-
-
Muchmore, S.W.1
Sattler, M.2
Liang, H.3
-
28
-
-
1842332735
-
Bcl-x(L) forms an ion channel in synthetic lipid membranes
-
10.1038/385353a0
-
AJ Minn P Velez SL Schendel 1997 Bcl-x(L) forms an ion channel in synthetic lipid membranes Nature 385 353 357 10.1038/385353a0
-
(1997)
Nature
, vol.385
, pp. 353-357
-
-
Minn, A.J.1
Velez, P.2
Schendel, S.L.3
-
29
-
-
9844257587
-
Inhibition of Bax channel-forming activity by Bcl-2
-
10.1126/science.277.5324.370
-
B Antonsson F Conti A Ciavatta 1997 Inhibition of Bax channel-forming activity by Bcl-2 Science 277 370 372 10.1126/science.277.5324.370
-
(1997)
Science
, vol.277
, pp. 370-372
-
-
Antonsson, B.1
Conti, F.2
Ciavatta, A.3
-
30
-
-
45549094799
-
Bench-to-bedside review: Mitochondrial injury, oxidative stress and apoptosis-there is nothing more practical than a good theory
-
10.1186/cc6779
-
H Bayir VE Kagan 2008 Bench-to-bedside review: Mitochondrial injury, oxidative stress and apoptosis-there is nothing more practical than a good theory Crit Care 12 206 10.1186/cc6779
-
(2008)
Crit Care
, vol.12
, pp. 206
-
-
Bayir, H.1
Kagan, V.E.2
-
31
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
-
10.1038/47513
-
T Nakagawa H Zhu N Morishima 2000 Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta Nature 403 98 103 10.1038/47513
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
-
32
-
-
33645124763
-
Endoplasmic reticulum stress induces apoptosis by an apoptosome-dependent but caspase 12-independent mechanism
-
10.1074/jbc.M509110200
-
F Di Sano E Ferraro R Tufi T Achsel M Piacentini F Cecconi 2006 Endoplasmic reticulum stress induces apoptosis by an apoptosome-dependent but caspase 12-independent mechanism J Biol Chem 281 2693 2700 10.1074/jbc. M509110200
-
(2006)
J Biol Chem
, vol.281
, pp. 2693-2700
-
-
Di Sano, F.1
Ferraro, E.2
Tufi, R.3
Achsel, T.4
Piacentini, M.5
Cecconi, F.6
-
33
-
-
1842843855
-
Roles of CHOP/GADD153 in endoplasmic reticulum stress
-
10.1038/sj.cdd.4401373
-
S Oyadomari M Mori 2004 Roles of CHOP/GADD153 in endoplasmic reticulum stress Cell Death Differ 11 381 389 10.1038/sj.cdd.4401373
-
(2004)
Cell Death Differ
, vol.11
, pp. 381-389
-
-
Oyadomari, S.1
Mori, M.2
-
34
-
-
33646175602
-
Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice
-
10.1038/nature04656
-
M Saleh JC Mathison MK Wolinski 2006 Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice Nature 440 1064 1068 10.1038/nature04656
-
(2006)
Nature
, vol.440
, pp. 1064-1068
-
-
Saleh, M.1
Mathison, J.C.2
Wolinski, M.K.3
-
35
-
-
0035038613
-
Triggering of apoptosis by cathepsins
-
10.1038/sj.cdd.4400859
-
M Leist M Jaattela 2001 Triggering of apoptosis by cathepsins Cell Death Differ 8 324 326 10.1038/sj.cdd.4400859
-
(2001)
Cell Death Differ
, vol.8
, pp. 324-326
-
-
Leist, M.1
Jaattela, M.2
-
36
-
-
0033832629
-
Noncaspase proteases in apoptosis
-
10.1038/sj.leu.2401879
-
DE Johnson 2000 Noncaspase proteases in apoptosis Leukemia 14 1695 1703 10.1038/sj.leu.2401879
-
(2000)
Leukemia
, vol.14
, pp. 1695-1703
-
-
Johnson, D.E.1
-
37
-
-
33646513917
-
Cysteine cathepsins in the immune response
-
10.1111/j.1399-0039.2006.00585.x
-
T Zavasnik-Bergant B Turk 2006 Cysteine cathepsins in the immune response Tissue Antigens 67 349 355 10.1111/j.1399-0039.2006.00585.x
-
(2006)
Tissue Antigens
, vol.67
, pp. 349-355
-
-
Zavasnik-Bergant, T.1
Turk, B.2
-
38
-
-
35848948133
-
Cysteine proteases: Destruction ability versus immunomodulation capacity in immune cells
-
10.1515/BC.2007.144
-
T Zavasnik-Bergant B Turk 2007 Cysteine proteases: destruction ability versus immunomodulation capacity in immune cells Biol Chem 388 1141 1149 10.1515/BC.2007.144
-
(2007)
Biol Chem
, vol.388
, pp. 1141-1149
-
-
Zavasnik-Bergant, T.1
Turk, B.2
-
39
-
-
33344457969
-
Cathepsin-regulated apoptosis
-
10.1007/s10495-006-3486-y
-
CE Chwieralski T Welte F Buhling 2006 Cathepsin-regulated apoptosis Apoptosis 11 143 149 10.1007/s10495-006-3486-y
-
(2006)
Apoptosis
, vol.11
, pp. 143-149
-
-
Chwieralski, C.E.1
Welte, T.2
Buhling, F.3
-
40
-
-
0035887215
-
Sphingosine-induced apoptosis is dependent on lysosomal proteases
-
10.1042/0264-6021:3590335
-
K Kagedal M Zhao I Svensson UT Brunk 2001 Sphingosine-induced apoptosis is dependent on lysosomal proteases Biochem J 359 335 343 10.1042/0264-6021: 3590335
-
(2001)
Biochem J
, vol.359
, pp. 335-343
-
-
Kagedal, K.1
Zhao, M.2
Svensson, I.3
Brunk, U.T.4
-
42
-
-
0034948738
-
The autophagosomal-lysosomal compartment in programmed cell death
-
10.1038/sj.cdd.4400852
-
W Bursch 2001 The autophagosomal-lysosomal compartment in programmed cell death Cell Death Differ 8 569 581 10.1038/sj.cdd.4400852
-
(2001)
Cell Death Differ
, vol.8
, pp. 569-581
-
-
Bursch, W.1
-
43
-
-
0141814639
-
Bacterial pathogens modulate an apoptosis differentiation program in human neutrophils
-
10.1073/pnas.1833375100
-
SD Kobayashi KR Braughton AR Whitney 2003 Bacterial pathogens modulate an apoptosis differentiation program in human neutrophils Proc Natl Acad Sci USA 100 10948 10953 10.1073/pnas.1833375100
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10948-10953
-
-
Kobayashi, S.D.1
Braughton, K.R.2
Whitney, A.R.3
-
44
-
-
59449086954
-
Streptolysin O promotes group a streptococcus immune evasion by accelerated macrophage apoptosis
-
10.1074/jbc.M804632200
-
AM Timmer JC Timmer MA Pence 2009 Streptolysin O promotes group a streptococcus immune evasion by accelerated macrophage apoptosis J Biol Chem 284 862 871 10.1074/jbc.M804632200
-
(2009)
J Biol Chem
, vol.284
, pp. 862-871
-
-
Timmer, A.M.1
Timmer, J.C.2
Pence, M.A.3
-
45
-
-
44449144438
-
Discovery of a widely distributed toxin biosynthetic gene cluster
-
10.1073/pnas.0801338105
-
SW Lee DA Mitchell AL Markley 2008 Discovery of a widely distributed toxin biosynthetic gene cluster Proc Natl Acad Sci USA 105 5879 5884 10.1073/pnas.0801338105
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 5879-5884
-
-
Lee, S.W.1
Mitchell, D.A.2
Markley, A.L.3
-
46
-
-
17644385827
-
Mutational analysis of the group A streptococcal operon encoding streptolysin S and its virulence role in invasive infection
-
10.1111/j.1365-2958.2005.04583.x
-
V Datta SM Myskowski LA Kwinn 2005 Mutational analysis of the group A streptococcal operon encoding streptolysin S and its virulence role in invasive infection Mol Microbiol 56 681 695 10.1111/j.1365-2958.2005.04583.x
-
(2005)
Mol Microbiol
, vol.56
, pp. 681-695
-
-
Datta, V.1
Myskowski, S.M.2
Kwinn, L.A.3
-
47
-
-
58149278915
-
Streptococcus pyogenes induces oncosis in macrophages through the activation of an inflammatory programmed ce
-
O Goldmann I Sastalla M Wos-Oxley M Rohde E Medina 2009 Streptococcus pyogenes induces oncosis in macrophages through the activation of an inflammatory programmed ce Cell Microbiol 11 138 155
-
(2009)
Cell Microbiol
, vol.11
, pp. 138-155
-
-
Goldmann, O.1
Sastalla, I.2
Wos-Oxley, M.3
Rohde, M.4
Medina, E.5
-
48
-
-
0030070367
-
Listeria monocytogenes induces apoptosis of infected hepatocytes
-
HW Rogers MP Callery B Deck ER Unanue 1996 Listeria monocytogenes induces apoptosis of infected hepatocytes J Immunol 156 679 684
-
(1996)
J Immunol
, vol.156
, pp. 679-684
-
-
Rogers, H.W.1
Callery, M.P.2
Deck, B.3
Unanue, E.R.4
-
50
-
-
0029939168
-
Apoptosis of mouse dendritic cells is triggered by listeriolysin, the major virulence determinant of Listeria monocytogenes
-
10.1111/j.1365-2958.1996.tb02494.x
-
CA Guzman E Domann M Rohde 1996 Apoptosis of mouse dendritic cells is triggered by listeriolysin, the major virulence determinant of Listeria monocytogenes Mol Microbiol 20 119 126 10.1111/j.1365-2958.1996.tb02494.x
-
(1996)
Mol Microbiol
, vol.20
, pp. 119-126
-
-
Guzman, C.A.1
Domann, E.2
Rohde, M.3
-
52
-
-
0034114758
-
Apoptosis induced by Staphylococcus aureus in epithelial cells utilizes a mechanism involving caspases 8 and 3
-
10.1128/IAI.68.5.2998-3001.2000
-
CA Wesson J Deringer LE Liou KW Bayles GA Bohach WR Trumble 2000 Apoptosis induced by Staphylococcus aureus in epithelial cells utilizes a mechanism involving caspases 8 and 3 Infect Immun 68 2998 3001 10.1128/IAI.68.5.2998-3001.2000
-
(2000)
Infect Immun
, vol.68
, pp. 2998-3001
-
-
Wesson, C.A.1
Deringer, J.2
Liou, L.E.3
Bayles, K.W.4
Bohach, G.A.5
Trumble, W.R.6
-
53
-
-
0034234669
-
The modulation of host cell apoptosis by intracellular bacterial pathogens
-
10.1016/S0966-842X(00)01784-4
-
LY Gao YA Kwaik 2000 The modulation of host cell apoptosis by intracellular bacterial pathogens Trends Microbiol 8 306 313 10.1016/S0966-842X(00)01784-4
-
(2000)
Trends Microbiol
, vol.8
, pp. 306-313
-
-
Gao, L.Y.1
Kwaik, Y.A.2
-
54
-
-
49149125956
-
Subversion of a lysosomal pathway regulating neutrophil apoptosis by a major bacterial toxin, pyocyanin
-
LR Prince SM Bianchi KM Vaughan 2008 Subversion of a lysosomal pathway regulating neutrophil apoptosis by a major bacterial toxin, pyocyanin J Immunol 180 3502 3511
-
(2008)
J Immunol
, vol.180
, pp. 3502-3511
-
-
Prince, L.R.1
Bianchi, S.M.2
Vaughan, K.M.3
-
55
-
-
33845222309
-
The contribution of cytolethal distending toxin to bacterial pathogenesis
-
10.1080/10408410601023557
-
JL Smith DO Bayles 2006 The contribution of cytolethal distending toxin to bacterial pathogenesis Crit Rev Microbiol 32 227 248 10.1080/ 10408410601023557
-
(2006)
Crit Rev Microbiol
, vol.32
, pp. 227-248
-
-
Smith, J.L.1
Bayles, D.O.2
-
56
-
-
0027170478
-
Activation with superantigens induces programmed death in antigen-primed CD4 + class II + major histocompatibility complex T lymphocytes via a CD11a/CD18-dependent mechanism
-
10.1002/eji.1830230718
-
NK Damle G Leytze K Klussman JA Ledbetter 1993 Activation with superantigens induces programmed death in antigen-primed CD4 + class II + major histocompatibility complex T lymphocytes via a CD11a/CD18-dependent mechanism Eur J Immunol 23 1513 1522 10.1002/eji.1830230718
-
(1993)
Eur J Immunol
, vol.23
, pp. 1513-1522
-
-
Damle, N.K.1
Leytze, G.2
Klussman, K.3
Ledbetter, J.A.4
-
58
-
-
0028983364
-
Selective depletion of v beta-bearing T cells in patients with severe invasive group A streptococcal infections and streptococcal toxic shock syndrome Ontario Streptococcal study project
-
R Watanabe-Ohnishi DE Low A McGeer 1995 Selective depletion of V beta-bearing T cells in patients with severe invasive group A streptococcal infections and streptococcal toxic shock syndrome Ontario Streptococcal study project J Infect Dis 171 74 84
-
(1995)
J Infect Dis
, vol.171
, pp. 74-84
-
-
Watanabe-Ohnishi, R.1
Low, D.E.2
McGeer, A.3
-
59
-
-
0033761316
-
CD95/CD95 ligand interactions on epithelial cells in host defense to Pseudomonas aeruginosa
-
10.1126/science.290.5491.527
-
H Grassme S Kirschnek J Riethmueller 2000 CD95/CD95 ligand interactions on epithelial cells in host defense to Pseudomonas aeruginosa Science 290 527 530 10.1126/science.290.5491.527
-
(2000)
Science
, vol.290
, pp. 527-530
-
-
Grassme, H.1
Kirschnek, S.2
Riethmueller, J.3
-
60
-
-
33745012076
-
Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis
-
10.1084/jem.20060206
-
M Lara-Tejero FS Sutterwala Y Ogura 2006 Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis J Exp Med 203 1407 1412 10.1084/jem.20060206
-
(2006)
J Exp Med
, vol.203
, pp. 1407-1412
-
-
Lara-Tejero, M.1
Sutterwala, F.S.2
Ogura, Y.3
-
61
-
-
34848866958
-
Pyroptosis and host cell death responses during Salmonella infection
-
10.1111/j.1462-5822.2007.01036.x
-
SL Fink BT Cookson 2007 Pyroptosis and host cell death responses during Salmonella infection Cell Microbiol 9 2562 2570 10.1111/j.1462-5822.2007.01036.x
-
(2007)
Cell Microbiol
, vol.9
, pp. 2562-2570
-
-
Fink, S.L.1
Cookson, B.T.2
-
62
-
-
0035283318
-
Pro-inflammatory programmed cell death
-
10.1016/S0966-842X(00)01936-3
-
BT Cookson MA Brennan 2001 Pro-inflammatory programmed cell death Trends Microbiol 9 113 114 10.1016/S0966-842X(00)01936-3
-
(2001)
Trends Microbiol
, vol.9
, pp. 113-114
-
-
Cookson, B.T.1
Brennan, M.A.2
-
63
-
-
33845478357
-
The inflammatory caspases: Guardians against infections and sepsis
-
10.1038/sj.cdd.4402026
-
AM Scott M Saleh 2007 The inflammatory caspases: guardians against infections and sepsis Cell Death Differ 14 23 31 10.1038/sj.cdd.4402026
-
(2007)
Cell Death Differ
, vol.14
, pp. 23-31
-
-
Scott, A.M.1
Saleh, M.2
-
64
-
-
0032548919
-
Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE
-
10.1016/S0092-8674(00)80943-5
-
S Wang M Miura YK Jung H Zhu E Li J Yuan 1998 Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE Cell 92 501 509 10.1016/S0092-8674(00)80943-5
-
(1998)
Cell
, vol.92
, pp. 501-509
-
-
Wang, S.1
Miura, M.2
Jung, Y.K.3
Zhu, H.4
Li, E.5
Yuan, J.6
-
65
-
-
0036120378
-
Listeria monocytogenes infection in caspase-11-deficient mice
-
10.1128/IAI.70.5.2657-2664.2002
-
NJ Mueller RA Wilkinson JA Fishman 2002 Listeria monocytogenes infection in caspase-11-deficient mice Infect Immun 70 2657 2664 10.1128/IAI.70.5.2657- 2664.2002
-
(2002)
Infect Immun
, vol.70
, pp. 2657-2664
-
-
Mueller, N.J.1
Wilkinson, R.A.2
Fishman, J.A.3
-
66
-
-
33845497181
-
Inflammatory caspases and inflammasomes: Master switches of inflammation
-
10.1038/sj.cdd.4402038
-
F Martinon J Tschopp 2007 Inflammatory caspases and inflammasomes: master switches of inflammation Cell Death Differ 14 10 22 10.1038/sj.cdd.4402038
-
(2007)
Cell Death Differ
, vol.14
, pp. 10-22
-
-
Martinon, F.1
Tschopp, J.2
-
67
-
-
33746028777
-
Intracellular pattern recognition receptors in the host response
-
10.1038/nature04946
-
E Meylan J Tschopp M Karin 2006 Intracellular pattern recognition receptors in the host response Nature 442 39 44 10.1038/nature04946
-
(2006)
Nature
, vol.442
, pp. 39-44
-
-
Meylan, E.1
Tschopp, J.2
Karin, M.3
-
68
-
-
36849045915
-
The inflammasome: A danger sensing complex triggering innate immunity
-
10.1016/j.coi.2007.09.002
-
V Petrilli C Dostert DA Muruve J Tschopp 2007 The inflammasome: a danger sensing complex triggering innate immunity Curr Opin Immunol 19 615 622 10.1016/j.coi.2007.09.002
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 615-622
-
-
Petrilli, V.1
Dostert, C.2
Muruve, D.A.3
Tschopp, J.4
-
69
-
-
0028175838
-
Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity
-
D Perregaux CA Gabel 1994 Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity J Biol Chem 269 15195 15203
-
(1994)
J Biol Chem
, vol.269
, pp. 15195-15203
-
-
Perregaux, D.1
Gabel, C.A.2
-
70
-
-
34548670965
-
Inflammasomes in inflammatory disorders: The role of TLRs and their interactions with NLRs
-
10.1007/s00281-007-0081-4
-
CE Becker LA O'Neill 2007 Inflammasomes in inflammatory disorders: the role of TLRs and their interactions with NLRs Semin Immunopathol 29 239 248 10.1007/s00281-007-0081-4
-
(2007)
Semin Immunopathol
, vol.29
, pp. 239-248
-
-
Becker, C.E.1
O'Neill, L.A.2
-
71
-
-
38049083888
-
Primer: Inflammasomes and interleukin 1beta in inflammatory disorders
-
10.1038/ncprheum0681
-
LD Church GP Cook MF McDermott 2008 Primer: inflammasomes and interleukin 1beta in inflammatory disorders Nat Clin Pract Rheumatol 4 34 42 10.1038/ncprheum0681
-
(2008)
Nat Clin Pract Rheumatol
, vol.4
, pp. 34-42
-
-
Church, L.D.1
Cook, G.P.2
McDermott, M.F.3
-
72
-
-
33744464740
-
Cytosolic flagellin requires IPAF for activation of caspase-1 and interleukin 1β in Salmonella-infected macrophages
-
10.1038/ni1346
-
L Franchi A Amer M Body-Malapel 2006 Cytosolic flagellin requires IPAF for activation of caspase-1 and interleukin 1β in Salmonella-infected macrophages Nat Immunol 7 576 582 10.1038/ni1346
-
(2006)
Nat Immunol
, vol.7
, pp. 576-582
-
-
Franchi, L.1
Amer, A.2
Body-Malapel, M.3
-
73
-
-
34548406570
-
Restriction of Legionella pneumophila growth in macrophages requires the concerted action of cytokine and Naip5/IPAF signalling pathways
-
10.1111/j.1462-5822.2007.00963.x
-
J Coers RE Vance MF Fontana WF Dietrich 2007 Restriction of Legionella pneumophila growth in macrophages requires the concerted action of cytokine and Naip5/IPAF signalling pathways Cell Microbiol 9 2344 2357 10.1111/j.1462-5822. 2007.00963.x
-
(2007)
Cell Microbiol
, vol.9
, pp. 2344-2357
-
-
Coers, J.1
Vance, R.E.2
Fontana, M.F.3
Dietrich, W.F.4
-
74
-
-
34547756483
-
Caspase-1 inflammasomes in infection and inflammation
-
10.1189/jlb.1206756
-
M Lamkanfi TD Kanneganti L Franchi G Nunez 2007 Caspase-1 inflammasomes in infection and inflammation J Leukoc Biol 82 220 225 10.1189/jlb.1206756
-
(2007)
J Leukoc Biol
, vol.82
, pp. 220-225
-
-
Lamkanfi, M.1
Kanneganti, T.D.2
Franchi, L.3
Nunez, G.4
-
75
-
-
33747191203
-
The inflammasome: First line of the immune response to cell stress
-
10.1016/j.cell.2006.08.002
-
Y Ogura FS Sutterwala RA Flavell 2006 The inflammasome: first line of the immune response to cell stress Cell 126 659 662 10.1016/j.cell.2006.08.002
-
(2006)
Cell
, vol.126
, pp. 659-662
-
-
Ogura, Y.1
Sutterwala, F.S.2
Flavell, R.A.3
-
76
-
-
0028984948
-
Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock
-
10.1016/0092-8674(95)90490-5
-
P Li H Allen S Banerjee 1995 Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock Cell 80 401 411 10.1016/0092-8674(95)90490-5
-
(1995)
Cell
, vol.80
, pp. 401-411
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
-
77
-
-
1542287347
-
Neutrophil extracellular traps kill bacteria
-
10.1126/science.1092385
-
V Brinkmann U Reichard C Goosmann 2004 Neutrophil extracellular traps kill bacteria Science 303 1532 1535 10.1126/science.1092385
-
(2004)
Science
, vol.303
, pp. 1532-1535
-
-
Brinkmann, V.1
Reichard, U.2
Goosmann, C.3
-
78
-
-
33846432787
-
Novel cell death program leads to neutrophil extracellular traps
-
10.1083/jcb.200606027
-
TA Fuchs U Abed C Goosmann 2007 Novel cell death program leads to neutrophil extracellular traps J Cell Biol 176 231 241 10.1083/jcb.200606027
-
(2007)
J Cell Biol
, vol.176
, pp. 231-241
-
-
Fuchs, T.A.1
Abed, U.2
Goosmann, C.3
-
79
-
-
48849106973
-
ETosis: A novel cell death pathway
-
10.1126/stke.121pe25
-
F Wartha B Henriques-Normark 2008 ETosis: a novel cell death pathway Sci Signal 1 pe25 10.1126/stke.121pe25
-
(2008)
Sci Signal
, vol.1
, pp. 25
-
-
Wartha, F.1
Henriques-Normark, B.2
-
80
-
-
34147188469
-
Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood
-
10.1038/nm1565
-
SR Clark AC Ma SA Tavener 2007 Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood Nat Med 13 463 469 10.1038/nm1565
-
(2007)
Nat Med
, vol.13
, pp. 463-469
-
-
Clark, S.R.1
Ma, A.C.2
Tavener, S.A.3
-
81
-
-
39549099917
-
Platelets, neutrophils, and neutrophil extracellular traps (NETs) in sepsis
-
10.1111/j.1538-7836.2007.02865.x
-
AC Ma P Kubes 2008 Platelets, neutrophils, and neutrophil extracellular traps (NETs) in sepsis J Thromb Haemost 6 415 420 10.1111/j.1538-7836.2007. 02865.x
-
(2008)
J Thromb Haemost
, vol.6
, pp. 415-420
-
-
Ma, A.C.1
Kubes, P.2
-
82
-
-
32944463724
-
Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms
-
10.1111/j.1462-5822.2005.00659.x
-
CF Urban U Reichard V Brinkmann A Zychlinsky 2006 Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms Cell Microbiol 8 668 676 10.1111/j.1462-5822.2005.00659.x
-
(2006)
Cell Microbiol
, vol.8
, pp. 668-676
-
-
Urban, C.F.1
Reichard, U.2
Brinkmann, V.3
Zychlinsky, A.4
-
83
-
-
34447525439
-
Beneficial suicide: Why neutrophils die to make NETs
-
10.1038/nrmicro1710
-
V Brinkmann A Zychlinsky 2007 Beneficial suicide: why neutrophils die to make NETs Nat Rev Microbiol 5 577 582 10.1038/nrmicro1710
-
(2007)
Nat Rev Microbiol
, vol.5
, pp. 577-582
-
-
Brinkmann, V.1
Zychlinsky, A.2
-
84
-
-
54049088538
-
Neutrophil-derived circulating free DNA (cf-DNA/NETs): A potential prognostic marker for posttraumatic development of inflammatory second hit and sepsis
-
10.1097/SHK.0b013e31816a6bb1
-
S Margraf T Logters J Reipen J Altrichter M Scholz J Windolf 2008 Neutrophil-derived circulating free DNA (cf-DNA/NETs): a potential prognostic marker for posttraumatic development of inflammatory second hit and sepsis Shock 30 352 358 10.1097/SHK.0b013e31816a6bb1
-
(2008)
Shock
, vol.30
, pp. 352-358
-
-
Margraf, S.1
Logters, T.2
Reipen, J.3
Altrichter, J.4
Scholz, M.5
Windolf, J.6
-
85
-
-
62449323653
-
M1 protein allows group A streptococcal survival in phagocyte extracellular traps through cathelicidin inhibition
-
in press
-
Lauth X, von Köckritz-Blickwede M, McNamara CW, et al. (2009) M1 protein allows group A streptococcal survival in phagocyte extracellular traps through cathelicidin inhibition. J Innate Immun (in press)
-
(2009)
J Innate Immun
-
-
Lauth, X.1
Von Köckritz-Blickwede, M.2
McNamara, C.W.3
-
86
-
-
48649083759
-
The IL-8 protease SpyCEP/ScpC of group A Streptococcus promotes resistance to neutrophil killing
-
10.1016/j.chom.2008.07.002
-
AS Zinkernagel AM Timmer MA Pence 2008 The IL-8 protease SpyCEP/ScpC of group A Streptococcus promotes resistance to neutrophil killing Cell Host Microbe 4 170 178 10.1016/j.chom.2008.07.002
-
(2008)
Cell Host Microbe
, vol.4
, pp. 170-178
-
-
Zinkernagel, A.S.1
Timmer, A.M.2
Pence, M.A.3
-
87
-
-
32944482526
-
An endonuclease allows Streptococcus pneumoniae to escape from neutrophil extracellular traps
-
10.1016/j.cub.2006.01.056
-
K Beiter F Wartha B Albiger S Normark A Zychlinsky B Henriques-Normark 2006 An endonuclease allows Streptococcus pneumoniae to escape from neutrophil extracellular traps Curr Biol 16 401 407 10.1016/j.cub.2006.01.056
-
(2006)
Curr Biol
, vol.16
, pp. 401-407
-
-
Beiter, K.1
Wartha, F.2
Albiger, B.3
Normark, S.4
Zychlinsky, A.5
Henriques-Normark, B.6
-
88
-
-
32944465559
-
DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps
-
10.1016/j.cub.2005.12.039
-
JT Buchanan AJ Simpson RK Aziz 2006 DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps Curr Biol 16 396 400 10.1016/j.cub.2005.12.039
-
(2006)
Curr Biol
, vol.16
, pp. 396-400
-
-
Buchanan, J.T.1
Simpson, A.J.2
Aziz, R.K.3
-
89
-
-
34547693093
-
DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection
-
10.1038/nm1612
-
MJ Walker A Hollands ML Sanderson-Smith 2007 DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection Nat Med 13 981 985 10.1038/nm1612
-
(2007)
Nat Med
, vol.13
, pp. 981-985
-
-
Walker, M.J.1
Hollands, A.2
Sanderson-Smith, M.L.3
-
90
-
-
0035338993
-
Sepsis-induced apoptosis causes progressive profound depletion of B and CD4 + T lymphocytes in humans
-
RS Hotchkiss KW Tinsley PE Swanson 2001 Sepsis-induced apoptosis causes progressive profound depletion of B and CD4 + T lymphocytes in humans J Immunol 166 6952 6963
-
(2001)
J Immunol
, vol.166
, pp. 6952-6963
-
-
Hotchkiss, R.S.1
Tinsley, K.W.2
Swanson, P.E.3
-
91
-
-
14844343217
-
Prolonged lymphopenia, lymphoid depletion, and hypoprolactinemia in children with nosocomial sepsis and multiple organ failure
-
KA Felmet MW Hall RS Clark R Jaffe JA Carcillo 2005 Prolonged lymphopenia, lymphoid depletion, and hypoprolactinemia in children with nosocomial sepsis and multiple organ failure J Immunol 174 3765 3772
-
(2005)
J Immunol
, vol.174
, pp. 3765-3772
-
-
Felmet, K.A.1
Hall, M.W.2
Clark, R.S.3
Jaffe, R.4
Carcillo, J.A.5
-
92
-
-
85047692486
-
Spleen depletion in neonatal sepsis and chorioamnionitis
-
10.1309/RV6E9BMC9954A2WU
-
P Toti C De Felice R Occhini 2004 Spleen depletion in neonatal sepsis and chorioamnionitis Am J Clin Pathol 122 765 771 10.1309/RV6E9BMC9954A2WU
-
(2004)
Am J Clin Pathol
, vol.122
, pp. 765-771
-
-
Toti, P.1
De Felice, C.2
Occhini, R.3
-
93
-
-
6444244641
-
Early circulating lymphocyte apoptosis in human septic shock is associated with poor outcome
-
10.1097/00024382-200212000-00001
-
Y Le Tulzo C Pangault A Gacouin 2002 Early circulating lymphocyte apoptosis in human septic shock is associated with poor outcome Shock 18 487 494 10.1097/00024382-200212000-00001
-
(2002)
Shock
, vol.18
, pp. 487-494
-
-
Le Tulzo, Y.1
Pangault, C.2
Gacouin, A.3
-
94
-
-
0036499162
-
Depletion of dendritic cells, but not macrophages, in patients with sepsis
-
RS Hotchkiss KW Tinsley PE Swanson 2002 Depletion of dendritic cells, but not macrophages, in patients with sepsis J Immunol 168 2493 2500
-
(2002)
J Immunol
, vol.168
, pp. 2493-2500
-
-
Hotchkiss, R.S.1
Tinsley, K.W.2
Swanson, P.E.3
-
95
-
-
0031110570
-
Cecal ligation and puncture (CLP) induces apoptosis in thymus, spleen, lung, and gut by an endotoxin and TNF-independent pathway
-
10.1097/00024382-199704000-00002
-
M Hiramatsu RS Hotchkiss IE Karl TG Buchman 1997 Cecal ligation and puncture (CLP) induces apoptosis in thymus, spleen, lung, and gut by an endotoxin and TNF-independent pathway Shock 7 247 253 10.1097/00024382- 199704000-00002
-
(1997)
Shock
, vol.7
, pp. 247-253
-
-
Hiramatsu, M.1
Hotchkiss, R.S.2
Karl, I.E.3
Buchman, T.G.4
-
96
-
-
0038106475
-
Sepsis induces apoptosis and profound depletion of splenic interdigitating and follicular dendritic cells
-
KW Tinsley MH Grayson PE Swanson 2003 Sepsis induces apoptosis and profound depletion of splenic interdigitating and follicular dendritic cells J Immunol 171 909 914
-
(2003)
J Immunol
, vol.171
, pp. 909-914
-
-
Tinsley, K.W.1
Grayson, M.H.2
Swanson, P.E.3
-
97
-
-
0037012470
-
Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-induced sepsis
-
10.1001/jama.287.13.1716
-
CM Coopersmith PE Stromberg WM Dunne 2002 Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-induced sepsis JAMA 287 1716 1721 10.1001/jama.287.13.1716
-
(2002)
JAMA
, vol.287
, pp. 1716-1721
-
-
Coopersmith, C.M.1
Stromberg, P.E.2
Dunne, W.M.3
-
98
-
-
28244480458
-
Silencing of Fas, but not caspase-8, in lung epithelial cells ameliorates pulmonary apoptosis, inflammation, and neutrophil influx after hemorrhagic shock and sepsis
-
M Perl CS Chung J Lomas-Neira 2005 Silencing of Fas, but not caspase-8, in lung epithelial cells ameliorates pulmonary apoptosis, inflammation, and neutrophil influx after hemorrhagic shock and sepsis Am J Pathol 167 1545 1559
-
(2005)
Am J Pathol
, vol.167
, pp. 1545-1559
-
-
Perl, M.1
Chung, C.S.2
Lomas-Neira, J.3
-
101
-
-
33750288937
-
Apoptosis and caspases regulate death and inflammation in sepsis
-
10.1038/nri1943
-
RS Hotchkiss DW Nicholson 2006 Apoptosis and caspases regulate death and inflammation in sepsis Nat Rev Immunol 6 813 822 10.1038/nri1943
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 813-822
-
-
Hotchkiss, R.S.1
Nicholson, D.W.2
-
102
-
-
0034604169
-
Apoptosis gone but not forgotten
-
10.1038/35011175
-
DR Green HM Beere 2000 Apoptosis gone but not forgotten Nature 405 28 29 10.1038/35011175
-
(2000)
Nature
, vol.405
, pp. 28-29
-
-
Green, D.R.1
Beere, H.M.2
-
103
-
-
1542511202
-
Death-defying immunity: Do apoptotic cells influence antigen processing and presentation?
-
10.1038/nri11308
-
ML Albert 2004 Death-defying immunity: do apoptotic cells influence antigen processing and presentation? Nat Rev Immunol 4 223 231 10.1038/nri11308
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 223-231
-
-
Albert, M.L.1
-
105
-
-
36849033963
-
TAM receptors are pleiotropic inhibitors of the innate immune response
-
10.1016/j.cell.2007.10.034
-
CV Rothlin S Ghosh EI Zuniga MB Oldstone G Lemke 2007 TAM receptors are pleiotropic inhibitors of the innate immune response Cell 131 1124 1136 10.1016/j.cell.2007.10.034
-
(2007)
Cell
, vol.131
, pp. 1124-1136
-
-
Rothlin, C.V.1
Ghosh, S.2
Zuniga, E.I.3
Oldstone, M.B.4
Lemke, G.5
-
106
-
-
32944474237
-
Innate immunity gone awry: Linking microbial infections to chronic inflammation and cancer
-
10.1016/j.cell.2006.02.016
-
M Karin T Lawrence V Nizet 2006 Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer Cell 124 823 835 10.1016/j.cell.2006.02.016
-
(2006)
Cell
, vol.124
, pp. 823-835
-
-
Karin, M.1
Lawrence, T.2
Nizet, V.3
-
107
-
-
0038312126
-
Adoptive transfer of apoptotic splenocytes worsens survival, whereas adoptive transfer of necrotic splenocytes improves survival in sepsis
-
10.1073/pnas.1031788100
-
RS Hotchkiss KC Chang MH Grayson 2003 Adoptive transfer of apoptotic splenocytes worsens survival, whereas adoptive transfer of necrotic splenocytes improves survival in sepsis Proc Natl Acad Sci USA 100 6724 6729 10.1073/pnas.1031788100
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 6724-6729
-
-
Hotchkiss, R.S.1
Chang, K.C.2
Grayson, M.H.3
-
108
-
-
0037142987
-
Association between mitochondrial dysfunction and severity and outcome of septic shock
-
10.1016/S0140-6736(02)09459-X
-
D Brealey M Brand I Hargreaves 2002 Association between mitochondrial dysfunction and severity and outcome of septic shock Lancet 360 219 223 10.1016/S0140-6736(02)09459-X
-
(2002)
Lancet
, vol.360
, pp. 219-223
-
-
Brealey, D.1
Brand, M.2
Hargreaves, I.3
-
109
-
-
0028329866
-
Oxidative stress in muscle and liver of rats with septic syndrome
-
10.1016/0891-5849(94)90121-X
-
S Llesuy P Evelson B Gonzalez-Flecha 1994 Oxidative stress in muscle and liver of rats with septic syndrome Free Radic Biol Med 16 445 451 10.1016/0891-5849(94)90121-X
-
(1994)
Free Radic Biol Med
, vol.16
, pp. 445-451
-
-
Llesuy, S.1
Evelson, P.2
Gonzalez-Flecha, B.3
-
110
-
-
0033120115
-
Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis
-
RS Hotchkiss PE Swanson CM Knudson 1999 Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis J Immunol 162 4148 4156
-
(1999)
J Immunol
, vol.162
, pp. 4148-4156
-
-
Hotchkiss, R.S.1
Swanson, P.E.2
Knudson, C.M.3
-
112
-
-
33847401104
-
Multiple triggers of cell death in sepsis: Death receptor and mitochondrial-mediated apoptosis
-
10.1096/fj.06-6805com
-
KC Chang J Unsinger CG Davis 2007 Multiple triggers of cell death in sepsis: death receptor and mitochondrial-mediated apoptosis FASEB J 21 708 719 10.1096/fj.06-6805com
-
(2007)
FASEB J
, vol.21
, pp. 708-719
-
-
Chang, K.C.1
Unsinger, J.2
Davis, C.G.3
-
113
-
-
0142093069
-
Inhibition of Fas/Fas ligand signaling improves septic survival: Differential effects on macrophage apoptotic and functional capacity
-
10.1189/jlb.0102006
-
CS Chung GY Song J Lomas HH Simms IH Chaudry A Ayala 2003 Inhibition of Fas/Fas ligand signaling improves septic survival: differential effects on macrophage apoptotic and functional capacity J Leukoc Biol 74 344 351 10.1189/jlb.0102006
-
(2003)
J Leukoc Biol
, vol.74
, pp. 344-351
-
-
Chung, C.S.1
Song, G.Y.2
Lomas, J.3
Simms, H.H.4
Chaudry, I.H.5
Ayala, A.6
-
114
-
-
16644390415
-
Increased lymphoid tissue apoptosis in baboons with bacteremic shock
-
10.1097/01.shk.0000126648.58732.8c
-
PA Efron K Tinsley DJ Minnich 2004 Increased lymphoid tissue apoptosis in baboons with bacteremic shock Shock 21 566 571 10.1097/01.shk.0000126648.58732. 8c
-
(2004)
Shock
, vol.21
, pp. 566-571
-
-
Efron, P.A.1
Tinsley, K.2
Minnich, D.J.3
-
116
-
-
33646369401
-
B lymphocytes undergo apoptosis because of FcγRIIb stress response to infection: A novel mechanism of cell death in sepsis
-
10.1097/01.shk.0000196496.72553.78
-
F Pinheiro-da-Silva M Chiamolera N Charles 2006 B lymphocytes undergo apoptosis because of FcγRIIb stress response to infection: a novel mechanism of cell death in sepsis Shock 25 61 65 10.1097/01.shk.0000196496. 72553.78
-
(2006)
Shock
, vol.25
, pp. 61-65
-
-
Pinheiro-Da-Silva, F.1
Chiamolera, M.2
Charles, N.3
-
117
-
-
0035829852
-
Intensive insulin therapy in the critically ill patients
-
10.1056/NEJMoa011300
-
G van den Berghe P Wouters F Weekers 2001 Intensive insulin therapy in the critically ill patients N Engl J Med 345 1359 1367 10.1056/NEJMoa011300
-
(2001)
N Engl J Med
, vol.345
, pp. 1359-1367
-
-
Van Den Berghe, G.1
Wouters, P.2
Weekers, F.3
-
118
-
-
0035826096
-
Efficacy and safety of recombinant human activated protein C for severe sepsis
-
10.1056/NEJM200103083441001
-
GR Bernard JL Vincent PF Laterre 2001 Efficacy and safety of recombinant human activated protein C for severe sepsis N Engl J Med 344 699 709 10.1056/NEJM200103083441001
-
(2001)
N Engl J Med
, vol.344
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.L.2
Laterre, P.F.3
-
119
-
-
34247632571
-
The apoptotic pathway as a therapeutic target in sepsis
-
10.2174/138945007780362764
-
DE Wesche-Soldato RZ Swan CS Chung A Ayala 2007 The apoptotic pathway as a therapeutic target in sepsis Curr Drug Targets 8 493 500 10.2174/ 138945007780362764
-
(2007)
Curr Drug Targets
, vol.8
, pp. 493-500
-
-
Wesche-Soldato, D.E.1
Swan, R.Z.2
Chung, C.S.3
Ayala, A.4
-
120
-
-
14944381279
-
Emerging role of Akt kinase/protein kinase B signaling in pathophysiology of diabetes and its complications
-
J Zdychova R Komers 2005 Emerging role of Akt kinase/protein kinase B signaling in pathophysiology of diabetes and its complications Physiol Res 54 1 16
-
(2005)
Physiol Res
, vol.54
, pp. 1-16
-
-
Zdychova, J.1
Komers, R.2
-
121
-
-
2942738936
-
Leukocyte and endothelial cell interactions in sepsis: Relevance of the protein C pathway
-
10.1097/01.CCM.0000128037.72072.22
-
DE Joyce DR Nelson BW Grinnell 2004 Leukocyte and endothelial cell interactions in sepsis: relevance of the protein C pathway Crit Care Med 32 S280 S286 10.1097/01.CCM.0000128037.72072.22
-
(2004)
Crit Care Med
, vol.32
-
-
Joyce, D.E.1
Nelson, D.R.2
Grinnell, B.W.3
-
122
-
-
0035815747
-
Gene expression profile of antithrombotic protein C defines new mechanisms modulating inflammation and apoptosis
-
10.1074/jbc.C100017200
-
DE Joyce L Gelbert A Ciaccia B DeHoff BW Grinnell 2001 Gene expression profile of antithrombotic protein C defines new mechanisms modulating inflammation and apoptosis J Biol Chem 276 11199 11203 10.1074/jbc.C100017200
-
(2001)
J Biol Chem
, vol.276
, pp. 11199-11203
-
-
Joyce, D.E.1
Gelbert, L.2
Ciaccia, A.3
Dehoff, B.4
Grinnell, B.W.5
-
123
-
-
0033431682
-
Prevention of lymphocyte cell death in sepsis improves survival in mice
-
10.1073/pnas.96.25.14541
-
RS Hotchkiss KW Tinsley PE Swanson 1999 Prevention of lymphocyte cell death in sepsis improves survival in mice Proc Natl Acad Sci USA 96 14541 14546 10.1073/pnas.96.25.14541
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 14541-14546
-
-
Hotchkiss, R.S.1
Tinsley, K.W.2
Swanson, P.E.3
-
124
-
-
3442885900
-
Improved survival in experimental sepsis with an orally administered inhibitor of apoptosis
-
10.1096/fj.03-1230com
-
JG Weaver MS Rouse JM Steckelberg AD Badley 2004 Improved survival in experimental sepsis with an orally administered inhibitor of apoptosis FASEB J 18 1185 1191 10.1096/fj.03-1230com
-
(2004)
FASEB J
, vol.18
, pp. 1185-1191
-
-
Weaver, J.G.1
Rouse, M.S.2
Steckelberg, J.M.3
Badley, A.D.4
-
125
-
-
0034908235
-
Inhibition of Fas signaling prevents hepatic injury and improves organ blood flow during sepsis
-
10.1067/msy.2001.116540
-
CS Chung S Yang GY Song 2001 Inhibition of Fas signaling prevents hepatic injury and improves organ blood flow during sepsis Surgery 130 339 345 10.1067/msy.2001.116540
-
(2001)
Surgery
, vol.130
, pp. 339-345
-
-
Chung, C.S.1
Yang, S.2
Song, G.Y.3
-
126
-
-
0029084116
-
A stable nitroxide radical effectively decreases mucosal damage in experimental colitis
-
10.1136/gut.37.3.386
-
F Karmeli R Eliakim E Okon A Samuni D Rachmilewitz 1995 A stable nitroxide radical effectively decreases mucosal damage in experimental colitis Gut 37 386 393 10.1136/gut.37.3.386
-
(1995)
Gut
, vol.37
, pp. 386-393
-
-
Karmeli, F.1
Eliakim, R.2
Okon, E.3
Samuni, A.4
Rachmilewitz, D.5
-
127
-
-
33846409853
-
Treatment with a novel hemigramicidin-TEMPO conjugate prolongs survival in a rat model of lethal hemorrhagic shock
-
10.1097/01.sla.0000236626.57752.8e
-
CA Macias JW Chiao J Xiao 2007 Treatment with a novel hemigramicidin-TEMPO conjugate prolongs survival in a rat model of lethal hemorrhagic shock Ann Surg 245 305 314 10.1097/01.sla.0000236626.57752.8e
-
(2007)
Ann Surg
, vol.245
, pp. 305-314
-
-
MacIas, C.A.1
Chiao, J.W.2
Xiao, J.3
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