-
1
-
-
0034958947
-
Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
-
Angus, D. C., Linde-Zwirble, W. T., Lidicker, J., Clermont, G., Carcillo, J., and Pinsky, M. R. (2001) Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit. Care Med. 29, 1303-1310
-
(2001)
Crit. Care Med.
, vol.29
, pp. 1303-1310
-
-
Angus, D.C.1
Linde-Zwirble, W.T.2
Lidicker, J.3
Clermont, G.4
Carcillo, J.5
Pinsky, M.R.6
-
2
-
-
0037451929
-
The epidemiology of sepsis in the United States from 1979 through 2000
-
Martin, G. S., Mannino, D. M., Eaton, S., and Moss, M. (2003) The epidemiology of sepsis in the United States from 1979 through 2000. N. Engl. J. Med. 348, 1546-1554
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1546-1554
-
-
Martin, G.S.1
Mannino, D.M.2
Eaton, S.3
Moss, M.4
-
3
-
-
0024405418
-
Plasma tumor necrosis factor and mortality in critically ill septic patients
-
Debets, J. M., Kampmeijer, R., van der Linden, M. P., Buurman, W. A., and van der Linden, C. J. (1989) Plasma tumor necrosis factor and mortality in critically ill septic patients. Crit. Care Med. 17, 489-494
-
(1989)
Crit. Care Med.
, vol.17
, pp. 489-494
-
-
Debets, J.M.1
Kampmeijer, R.2
Van Der Linden, M.P.3
Buurman, W.A.4
Van Der Linden, C.J.5
-
4
-
-
0034015682
-
Cytokine signaling-regulation of the immune response in normal and critically ill states
-
Oberholzer, A., Oberholzer, C., and Moldawer, L. L. (2000) Cytokine signaling-regulation of the immune response in normal and critically ill states. Crit. Care Med. 28, N3-12
-
(2000)
Crit. Care Med.
, vol.28
-
-
Oberholzer, A.1
Oberholzer, C.2
Moldawer, L.L.3
-
5
-
-
15844382547
-
Increased soluble interleukin-1 type II receptor concentrations in postoperative patients and in patients with sepsis syndrome
-
Pruitt, J. H., Welborn, M. B., Edwards, P. D., Harward, T. R., Seeger, J. W., Martin, T. D., Smith, C., Kenney, J. A., Wesdorp, R. I., Meijer, S., et al. (1996) Increased soluble interleukin-1 type II receptor concentrations in postoperative patients and in patients with sepsis syndrome. Blood 87, 3282-3288
-
(1996)
Blood
, vol.87
, pp. 3282-3288
-
-
Pruitt, J.H.1
Welborn, M.B.2
Edwards, P.D.3
Harward, T.R.4
Seeger, J.W.5
Martin, T.D.6
Smith, C.7
Kenney, J.A.8
Wesdorp, R.I.9
Meijer, S.10
-
6
-
-
0028212610
-
Persistently elevated soluble tumor necrosis factor receptor and interleukin-1 receptor antagonist levels in critically ill patients
-
Rogy, M. A., Coyle, S. M., Oldenburg, H. S., Rock, C. S., Barie, P. S., Van Zee, K. J., Smith, C. G., Moldawer, L. L., and Lowry, S. F. (1994) Persistently elevated soluble tumor necrosis factor receptor and interleukin-1 receptor antagonist levels in critically ill patients. J. Am. Coll. Surg. 178, 132-138
-
(1994)
J. Am. Coll. Surg.
, vol.178
, pp. 132-138
-
-
Rogy, M.A.1
Coyle, S.M.2
Oldenburg, H.S.3
Rock, C.S.4
Barie, P.S.5
Van Zee, K.J.6
Smith, C.G.7
Moldawer, L.L.8
Lowry, S.F.9
-
7
-
-
0017737597
-
Delayed hypersensitivity: Indicator of acquired failure of host defenses in sepsis and trauma
-
Meakins, J. L., Pietsch, J. B., Bubenick, O., Kelly, R., Rode, H., Gordon, J., and MacLean, L. D. (1977) Delayed hypersensitivity: indicator of acquired failure of host defenses in sepsis and trauma. Ann. Surg. 186, 241-250
-
(1977)
Ann. Surg.
, vol.186
, pp. 241-250
-
-
Meakins, J.L.1
Pietsch, J.B.2
Bubenick, O.3
Kelly, R.4
Rode, H.5
Gordon, J.6
MacLean, L.D.7
-
8
-
-
0033090250
-
The effects of injury on the adaptive immune response
-
Lederer, J. A., Rodrick, M. L., and Mannick, J. A. (1999) The effects of injury on the adaptive immune response. Shock 11, 153-159
-
(1999)
Shock
, vol.11
, pp. 153-159
-
-
Lederer, J.A.1
Rodrick, M.L.2
Mannick, J.A.3
-
9
-
-
0035434019
-
Sepsis syndromes: Understanding the role of innate and acquired immunity
-
Oberholzer, A., Oberholzer, C., and Moldawer, L. L. (2001) Sepsis syndromes: understanding the role of innate and acquired immunity. Shock 16, 83-96
-
(2001)
Shock
, vol.16
, pp. 83-96
-
-
Oberholzer, A.1
Oberholzer, C.2
Moldawer, L.L.3
-
10
-
-
0028223194
-
Sepsis-induced apoptosis of the thymocytes in mice
-
Wang, S. D., Huang, K. J., Lin, Y. S., and Lei, H. Y. (1994) Sepsis-induced apoptosis of the thymocytes in mice. J. Immunol. 152, 5014-5021
-
(1994)
J. Immunol.
, vol.152
, pp. 5014-5021
-
-
Wang, S.D.1
Huang, K.J.2
Lin, Y.S.3
Lei, H.Y.4
-
11
-
-
0029880871
-
Differential induction of apoptosis in lymphoid tissues during sepsis: Variation in onset, frequency, and the nature of the mediators
-
Ayala, A., Herdon, C. D., Lehman, D. L., Ayala, C. A., and Chaudry, I. H. (1996) Differential induction of apoptosis in lymphoid tissues during sepsis: variation in onset, frequency, and the nature of the mediators. Blood 87, 4261-4275
-
(1996)
Blood
, vol.87
, pp. 4261-4275
-
-
Ayala, A.1
Herdon, C.D.2
Lehman, D.L.3
Ayala, C.A.4
Chaudry, I.H.5
-
12
-
-
0030739250
-
Apoptosis in lymphoid and parenchymal cells during sepsis: Findings in normal and T- and B-cell-deficient mice
-
Hotchkiss, R. S., Swanson, P. E., Cobb, J. P., Jacobson, A., Buchman, T. G., and Karl, I. E. (1997) Apoptosis in lymphoid and parenchymal cells during sepsis: findings in normal and T- and B-cell-deficient mice. Crit. Care Med. 25, 1298-1307
-
(1997)
Crit. Care Med.
, vol.25
, pp. 1298-1307
-
-
Hotchkiss, R.S.1
Swanson, P.E.2
Cobb, J.P.3
Jacobson, A.4
Buchman, T.G.5
Karl, I.E.6
-
13
-
-
0035976995
-
Role of apoptosis in Pseudomonas aeruginosa pneumonia
-
Hotchkiss, R. S., Dunne, W. M., Swanson, P. E., Davis, C. G., Tinsley, K W., Chang, K. C., Buchman, T. G., and Karl, I. E. (2001) Role of apoptosis in Pseudomonas aeruginosa pneumonia. Science 294, 1783
-
(2001)
Science
, vol.294
, pp. 1783
-
-
Hotchkiss, R.S.1
Dunne, W.M.2
Swanson, P.E.3
Davis, C.G.4
Tinsley, K.W.5
Chang, K.C.6
Buchman, T.G.7
Karl, I.E.8
-
14
-
-
0035026505
-
Increased apoptosis in lamina propria B cells during polymicrobial sepsis is FasL but not endotoxin mediated
-
Chung, C. S., Wang, W., Chaudry, I. H., and Ayala, A. (2001) Increased apoptosis in lamina propria B cells during polymicrobial sepsis is FasL but not endotoxin mediated. Am. J. Physiol. 280, G812-G818
-
(2001)
Am. J. Physiol.
, vol.280
-
-
Chung, C.S.1
Wang, W.2
Chaudry, I.H.3
Ayala, A.4
-
15
-
-
0033946085
-
Role of CuZn superoxide dismutase in regulating lymphocyte apoptosis during sepsis
-
Freeman, B. D., Reaume, A. G., Swanson, P. E., Epstein, C. J., Carlson, E. J., Buchman, T. G., Karl, I. E., and Hotchkiss, R. S. (2000) Role of CuZn superoxide dismutase in regulating lymphocyte apoptosis during sepsis. Crit. Care Med. 28, 1701-1708
-
(2000)
Crit. Care Med.
, vol.28
, pp. 1701-1708
-
-
Freeman, B.D.1
Reaume, A.G.2
Swanson, P.E.3
Epstein, C.J.4
Carlson, E.J.5
Buchman, T.G.6
Karl, I.E.7
Hotchkiss, R.S.8
-
16
-
-
0034177037
-
p53-dependent and -independent pathways of apoptotic cell death in sepsis
-
Hotchkiss, R. S., Tinsley, K. W., Hui, J. J., Chang, K. C., Swanson, P. E., Drewry, A. M., Buchman, T. G., and Karl, I. E. (2000) p53-dependent and -independent pathways of apoptotic cell death in sepsis. J. Immunol. 164, 3675-3680
-
(2000)
J. Immunol.
, vol.164
, pp. 3675-3680
-
-
Hotchkiss, R.S.1
Tinsley, K.W.2
Hui, J.J.3
Chang, K.C.4
Swanson, P.E.5
Drewry, A.M.6
Buchman, T.G.7
Karl, I.E.8
-
17
-
-
0033628936
-
Caspases -2, -3, -6, and -9, but not caspase-1, are activated in sepsis-induced thymocyte apoptosis
-
Tinsley, K. W., Cheng, S. L., Buchman, T. G., Chang, K. C., Hui, J. J., Swanson, P. E., Karl, I. E., and Hotchkiss, R. S. (2000) Caspases -2, -3, -6, and -9, but not caspase-1, are activated in sepsis-induced thymocyte apoptosis. Shock 13, 1-7
-
(2000)
Shock
, vol.13
, pp. 1-7
-
-
Tinsley, K.W.1
Cheng, S.L.2
Buchman, T.G.3
Chang, K.C.4
Hui, J.J.5
Swanson, P.E.6
Karl, I.E.7
Hotchkiss, R.S.8
-
18
-
-
2642599034
-
Increased mucosal B-lymphocyte apoptosis during polymicrobial sepsis is a Fas ligand but not an endotoxin-mediated process
-
Ayala, A., Xin Xu, Y., Ayala, C. A., Sonefeld, D. E., Karr, S. M., Evans, T. A., and Chaudry, I. H. (1998) Increased mucosal B-lymphocyte apoptosis during polymicrobial sepsis is a Fas ligand but not an endotoxin-mediated process. Blood 91, 1362-1372
-
(1998)
Blood
, vol.91
, pp. 1362-1372
-
-
Ayala, A.1
Xin Xu, Y.2
Ayala, C.A.3
Sonefeld, D.E.4
Karr, S.M.5
Evans, T.A.6
Chaudry, I.H.7
-
19
-
-
0037384023
-
Role of intestinal epithelial apoptosis in survival
-
Husain, K. D., and Coopersmith, C. M. (2003) Role of intestinal epithelial apoptosis in survival. Curr. Opin. Crit. Care 9, 159-163
-
(2003)
Curr. Opin. Crit. Care
, vol.9
, pp. 159-163
-
-
Husain, K.D.1
Coopersmith, C.M.2
-
20
-
-
0037012470
-
Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-induced sepsis
-
Coopersmith, C. M., Stromberg, P. E., Dunne, W. M., Davis, C. G., Amiot, D. M., II, Buchman, T. G., Karl, I. E., and Hotchkiss, R. S. (2002) Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-induced sepsis. J. Am. Med. Assoc. 287, 1716-1721
-
(2002)
J. Am. Med. Assoc.
, vol.287
, pp. 1716-1721
-
-
Coopersmith, C.M.1
Stromberg, P.E.2
Dunne, W.M.3
Davis, C.G.4
Amiot II, D.M.5
Buchman, T.G.6
Karl, I.E.7
Hotchkiss, R.S.8
-
21
-
-
0037709807
-
Sepsis from Pseudomonas aeruginosa pneumonia decreases intestinal proliferation and induces gut epithelial cell cycle arrest
-
Coopersmith, C. M., Stromberg, P. E., Davis, C. G., Dunne, W. M., Amiot, D. M., II, Karl, I. E., Hotchkiss, R. S., and Buchman, T. G. (2003) Sepsis from Pseudomonas aeruginosa pneumonia decreases intestinal proliferation and induces gut epithelial cell cycle arrest. Crit. Care Med. 31, 1630-1637
-
(2003)
Crit. Care Med.
, vol.31
, pp. 1630-1637
-
-
Coopersmith, C.M.1
Stromberg, P.E.2
Davis, C.G.3
Dunne, W.M.4
Amiot II, D.M.5
Karl, I.E.6
Hotchkiss, R.S.7
Buchman, T.G.8
-
22
-
-
0036152735
-
Overexpression of Bcl-2 in the intestinal epithelium improves survival in septic mice
-
Coopersmith, C. M., Chang, K. C., Swanson, P. E., Tinsley, K. W., Stromberg, P. E., Buchman, T. G., Karl, I. F., and Hotchkiss, R. S. (2002) Overexpression of Bcl-2 in the intestinal epithelium improves survival in septic mice. Crit. Care Med. 30, 195-201
-
(2002)
Crit. Care Med.
, vol.30
, pp. 195-201
-
-
Coopersmith, C.M.1
Chang, K.C.2
Swanson, P.E.3
Tinsley, K.W.4
Stromberg, P.E.5
Buchman, T.G.6
Karl, I.F.7
Hotchkiss, R.S.8
-
23
-
-
0032770246
-
Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction
-
Hotchkiss, R. S., Swanson, P. E., Freeman, B. D., Tinsley, K. W., Cobb, J. P., Matuschak, G. M., Buchman, T. G., and Karl, I. E. (1999) Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction. Crit. Care Med. 27, 1230-1251
-
(1999)
Crit. Care Med.
, vol.27
, pp. 1230-1251
-
-
Hotchkiss, R.S.1
Swanson, P.E.2
Freeman, B.D.3
Tinsley, K.W.4
Cobb, J.P.5
Matuschak, G.M.6
Buchman, T.G.7
Karl, I.E.8
-
24
-
-
8244231925
-
Intra-abdominal sepsis: An immunocytochemical study of the small intestine mucosa
-
Coutinho, H. B., Robalinho, T. I., Coutinho, V. B., Amorim, A. M., Furtado, A. F., Ferraz, A., Ferraz, E., Walker, F., King, G., Sewell, H. F., et al. (1997) Intra-abdominal sepsis: an immunocytochemical study of the small intestine mucosa. J. Clin. Pathol. 50, 294-298
-
(1997)
J. Clin. Pathol.
, vol.50
, pp. 294-298
-
-
Coutinho, H.B.1
Robalinho, T.I.2
Coutinho, V.B.3
Amorim, A.M.4
Furtado, A.F.5
Ferraz, A.6
Ferraz, E.7
Walker, F.8
King, G.9
Sewell, H.F.10
-
25
-
-
0041849685
-
Elevated nucleosome levels in systemic inflammation and sepsis
-
Zeerleder, S., Zwart, B., Wuillemin, W. A., Aarden, L. A., Groeneveld, A. B., Caliezi, C., van Nieuwenhuijze, A. E., van Mierlo, G. J., Eerenberg, A. J., Lammle, B., et al. (2003) Elevated nucleosome levels in systemic inflammation and sepsis. Crit. Care Med. 31, 1947-1951
-
(2003)
Crit. Care Med.
, vol.31
, pp. 1947-1951
-
-
Zeerleder, S.1
Zwart, B.2
Wuillemin, W.A.3
Aarden, L.A.4
Groeneveld, A.B.5
Caliezi, C.6
Van Nieuwenhuijze, A.E.7
Van Mierlo, G.J.8
Eerenberg, A.J.9
Lammle, B.10
-
26
-
-
0033431682
-
Prevention of lymphocyte cell death in sepsis improves survival in mice
-
Hotchkiss, R. S., Tinsley, K. W., Swanson, P. E., Chang, K. C., Cobb, J. P., Buchman, T. G., Korsmeyer, S. J., and Karl, I. E. (1999) Prevention of lymphocyte cell death in sepsis improves survival in mice. Proc. Natl. Acad. Sci. USA 96, 14541-14546
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 14541-14546
-
-
Hotchkiss, R.S.1
Tinsley, K.W.2
Swanson, P.E.3
Chang, K.C.4
Cobb, J.P.5
Buchman, T.G.6
Korsmeyer, S.J.7
Karl, I.E.8
-
27
-
-
5944251623
-
Caspase inhibitors improve survival in sepsis: A critical role of the lymphocyte
-
Hotchkiss, R. S., Chang, K. C., Swanson, P. E., Tinsley, K. W., Hui, J. J., Klender, P., Xanthoudakis, S., Roy, S., Black, C., Grimm, E., et al. (2000) Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte. Nat. Immunol. 1, 496-501
-
(2000)
Nat. Immunol.
, vol.1
, pp. 496-501
-
-
Hotchkiss, R.S.1
Chang, K.C.2
Swanson, P.E.3
Tinsley, K.W.4
Hui, J.J.5
Klender, P.6
Xanthoudakis, S.7
Roy, S.8
Black, C.9
Grimm, E.10
-
28
-
-
0038578608
-
Novel strategies for the treatment of sepsis
-
Riedemann, N. C., Guo, R. F., and Ward, P. A. (2003) Novel strategies for the treatment of sepsis. Nat. Med. 9, 517-524
-
(2003)
Nat. Med.
, vol.9
, pp. 517-524
-
-
Riedemann, N.C.1
Guo, R.F.2
Ward, P.A.3
-
29
-
-
0033120115
-
Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis
-
Hotchkiss, R. S., Swanson, P. E., Knudson, C. M., Chang, K. C., Cobb, J. P., Osborne, D. F., Zollner, K. M., Buchman, T. G., Korsmeyer, S. J., and Karl, I. E. (1999) Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis. J. Immunol. 162, 4148-4156
-
(1999)
J. Immunol.
, vol.162
, pp. 4148-4156
-
-
Hotchkiss, R.S.1
Swanson, P.E.2
Knudson, C.M.3
Chang, K.C.4
Cobb, J.P.5
Osborne, D.F.6
Zollner, K.M.7
Buchman, T.G.8
Korsmeyer, S.J.9
Karl, I.E.10
-
30
-
-
0142093069
-
Inhibition of Fas/Fas ligand signaling improves septic survival: Differential effects on macrophage apoptotic and functional capacity
-
Chung, C. S., Song, G. Y., Lomas, J., Simms, H. H., Chaudry, I. H., and Ayala, A. (2003) Inhibition of Fas/Fas ligand signaling improves septic survival: differential effects on macrophage apoptotic and functional capacity. J. Leukoc. Biol. 74, 344-351
-
(2003)
J. Leukoc. Biol.
, vol.74
, pp. 344-351
-
-
Chung, C.S.1
Song, G.Y.2
Lomas, J.3
Simms, H.H.4
Chaudry, I.H.5
Ayala, A.6
-
31
-
-
0037426726
-
The pathophysiology and treatment of sepsis
-
Hotchkiss, R. S., and Karl, I. E. (2003) The pathophysiology and treatment of sepsis. N. Engl. J. Med. 348, 138-150
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 138-150
-
-
Hotchkiss, R.S.1
Karl, I.E.2
-
32
-
-
0035071005
-
Apoptosis in sepsis: A new target for therapeutic exploration
-
Oberholzer, C., Oberholzer, A., Clare-Salzler, M., and Moldawer, L. L. (2001) Apoptosis in sepsis: a new target for therapeutic exploration. FASEB J. 15, 879-892
-
(2001)
FASEB J.
, vol.15
, pp. 879-892
-
-
Oberholzer, C.1
Oberholzer, A.2
Clare-Salzler, M.3
Moldawer, L.L.4
-
33
-
-
0032128437
-
In vivo analysis of Fas/FasL interactions in HIV-infected patients
-
Badley, A. D., Dockrell, D. H., Algeciras, A., Ziesmer, S., Landay, A., Lederman, M. M., Connick, E., Kessler, H., Kuritzkes, D., Lynch, D. H., et al. (1998) In vivo analysis of Fas/FasL interactions in HIV-infected patients. J. Clin. Invest. 102, 79-87
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 79-87
-
-
Badley, A.D.1
Dockrell, D.H.2
Algeciras, A.3
Ziesmer, S.4
Landay, A.5
Lederman, M.M.6
Connick, E.7
Kessler, H.8
Kuritzkes, D.9
Lynch, D.H.10
-
34
-
-
0034630359
-
Decreased HIV-associated T cell apoptosis by HIV protease inhibitors
-
Phenix, B. N., Angel, J. B., Mandy, F., Kravcik, S., Parato, K., Chambers, K. A., Gallicano, K., Hawley-Foss, N., Cassol, S., Cameron, D. W., et al. (2000) Decreased HIV-associated T cell apoptosis by HIV protease inhibitors. AIDS Res. Hum. Retroviruses 16, 559-567
-
(2000)
AIDS Res. Hum. Retroviruses
, vol.16
, pp. 559-567
-
-
Phenix, B.N.1
Angel, J.B.2
Mandy, F.3
Kravcik, S.4
Parato, K.5
Chambers, K.A.6
Gallicano, K.7
Hawley-Foss, N.8
Cassol, S.9
Cameron, D.W.10
-
35
-
-
0030868897
-
Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease
-
Autran, B., Carcelain, G., Li, T. S., Blanc, C., Mathez, D., Tubiana, R., Katlama, C., Debre, P., and Leibowitch, J. (1997) Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease. Science 277, 112-116
-
(1997)
Science
, vol.277
, pp. 112-116
-
-
Autran, B.1
Carcelain, G.2
Li, T.S.3
Blanc, C.4
Mathez, D.5
Tubiana, R.6
Katlama, C.7
Debre, P.8
Leibowitch, J.9
-
36
-
-
0035883068
-
Antiapoptotic mechanism of HIV protease inhibitors: Preventing mitochondrial transmembrane potential loss
-
Phenix, B. N., Lum, J. J., Nie, Z., Sanchez-Dardon, J., and Badley, A. D. (2001) Antiapoptotic mechanism of HIV protease inhibitors: preventing mitochondrial transmembrane potential loss. Blood 98, 1078-1085
-
(2001)
Blood
, vol.98
, pp. 1078-1085
-
-
Phenix, B.N.1
Lum, J.J.2
Nie, Z.3
Sanchez-Dardon, J.4
Badley, A.D.5
-
37
-
-
0018349233
-
Effect of sepsis on tissue adenine nucleotide levels
-
Chaudry, I. H., Wichterman, K. A., and Baue, A. E. (1979) Effect of sepsis on tissue adenine nucleotide levels. Surgery 85, 205-211
-
(1979)
Surgery
, vol.85
, pp. 205-211
-
-
Chaudry, I.H.1
Wichterman, K.A.2
Baue, A.E.3
-
38
-
-
0034132796
-
Comparison of the mortality and inflammatory response of two models of sepsis: Lipopolysaccharide vs. cecal ligation and puncture
-
Remick, D. G., Newcomb, D. E., Bolgos, G. L., and Call, D. R. (2000) Comparison of the mortality and inflammatory response of two models of sepsis: lipopolysaccharide vs. cecal ligation and puncture. Shock 13, 110-116
-
(2000)
Shock
, vol.13
, pp. 110-116
-
-
Remick, D.G.1
Newcomb, D.E.2
Bolgos, G.L.3
Call, D.R.4
-
39
-
-
0020520054
-
Evaluation of factors affecting mortality rate after sepsis in a murine cecal ligation and puncture model
-
Baker, C. C., Chaudry, I. H., Gaines, H. O., and Baue, A. E. (1983) Evaluation of factors affecting mortality rate after sepsis in a murine cecal ligation and puncture model. Surgery 94, 331-335
-
(1983)
Surgery
, vol.94
, pp. 331-335
-
-
Baker, C.C.1
Chaudry, I.H.2
Gaines, H.O.3
Baue, A.E.4
-
40
-
-
84869233580
-
Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; Approved standard-sixth edition
-
(M7-A6, N. d., ed) Wayne, Pennsylvania
-
National and Standards, C. L. (2003) Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard-sixth edition. In Approved Standards, 6th edition (M7-A6, N. d., ed) Wayne, Pennsylvania
-
(2003)
Approved Standards, 6th Edition
-
-
-
41
-
-
0037024752
-
Virologic response to nelfinavir-based regimens: Pharmacokinetics and drug resistance mutations (VI-RAPHAR study)
-
Pellegrin, I., Breilh, D., Montestruc, F., Caumont, A., Garrigue, I., Morlat, P., Le Camus, C., Saux, M. C., Fleury, H. J., and Pellegrin, J. L. (2002) Virologic response to nelfinavir-based regimens: pharmacokinetics and drug resistance mutations (VI-RAPHAR study). AIDS 16, 1331-1340
-
(2002)
AIDS
, vol.16
, pp. 1331-1340
-
-
Pellegrin, I.1
Breilh, D.2
Montestruc, F.3
Caumont, A.4
Garrigue, I.5
Morlat, P.6
Le Camus, C.7
Saux, M.C.8
Fleury, H.J.9
Pellegrin, J.L.10
-
42
-
-
0033257553
-
Endotoxin, sepsis, and the primrose path
-
O'Reilly, M., Newcomb, D. E., and Remick, D. (1999) Endotoxin, sepsis, and the primrose path. Shock 12, 411-420
-
(1999)
Shock
, vol.12
, pp. 411-420
-
-
O'Reilly, M.1
Newcomb, D.E.2
Remick, D.3
-
43
-
-
0025354406
-
Laboratory models of sepsis and septic shock
-
Fink, M. P., and Heard, S. O. (1990) Laboratory models of sepsis and septic shock. J. Surg. Res. 49, 186-196
-
(1990)
J. Surg. Res.
, vol.49
, pp. 186-196
-
-
Fink, M.P.1
Heard, S.O.2
-
44
-
-
0031606321
-
Animal models of sepsis and shock: A review and lessons learned
-
Deitch, E. A. (1998) Animal models of sepsis and shock: a review and lessons learned. Shock 9, 1-11
-
(1998)
Shock
, vol.9
, pp. 1-11
-
-
Deitch, E.A.1
-
45
-
-
0035019731
-
Tumor necrosis factor-dependent adhesions as a major protective mechanism early in septic peritonitis in mice
-
Echtenacher, B., Weigl, K., Lehn, N., and Mannel, D. N. (2001) Tumor necrosis factor-dependent adhesions as a major protective mechanism early in septic peritonitis in mice. Infect. Immun. 69, 3550-3555
-
(2001)
Infect. Immun.
, vol.69
, pp. 3550-3555
-
-
Echtenacher, B.1
Weigl, K.2
Lehn, N.3
Mannel, D.N.4
-
46
-
-
0026585007
-
Anti-tumor necrosis factor antibody therapy fails to prevent lethality after cecal ligation and puncture or endotoxemia
-
Eskandari, M. K., Bolgos, G., Miller, C., Nguyen, D. T., DeForge, L. E., and Remick, D. G. (1992) Anti-tumor necrosis factor antibody therapy fails to prevent lethality after cecal ligation and puncture or endotoxemia. J. Immunol. 148, 2724-2730
-
(1992)
J. Immunol.
, vol.148
, pp. 2724-2730
-
-
Eskandari, M.K.1
Bolgos, G.2
Miller, C.3
Nguyen, D.T.4
DeForge, L.E.5
Remick, D.G.6
-
47
-
-
0029900294
-
Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein
-
The Soluble TNF Receptor Sepsis Study Group
-
Fisher, C. J., Jr., Agosti, J. M., Opal, S. M., Lowry, S. F., Balk, R. A., Sadoff, J. C., Abraham, E., Schein, R. M., and Benjamin, E. (1996) Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein. The Soluble TNF Receptor Sepsis Study Group. N. Engl. J. Med. 334, 1697-1702
-
(1996)
N. Engl. J. Med.
, vol.334
, pp. 1697-1702
-
-
Fisher Jr., C.J.1
Agosti, J.M.2
Opal, S.M.3
Lowry, S.F.4
Balk, R.A.5
Sadoff, J.C.6
Abraham, E.7
Schein, R.M.8
Benjamin, E.9
-
48
-
-
0033969341
-
Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: A marker for prognosis and future therapeutic options
-
Gogos, C. A., Drosou, E., Bassaris, H. P., and Skoutelis, A. (2000) Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: a marker for prognosis and future therapeutic options. J. Infect. Dis. 181, 176-180
-
(2000)
J. Infect. Dis.
, vol.181
, pp. 176-180
-
-
Gogos, C.A.1
Drosou, E.2
Bassaris, H.P.3
Skoutelis, A.4
-
49
-
-
0032701390
-
Selective defects of T lymphocyte function in patients with lethal intraabdominal infection
-
Heidecke, C. D., Hensler, T., Weighardt, H., Zantl, N., Wagner, H., Siewert, J. R., and Holzmann, B. (1999) Selective defects of T lymphocyte function in patients with lethal intraabdominal infection. Am. J. Surg. 178, 288-292
-
(1999)
Am. J. Surg.
, vol.178
, pp. 288-292
-
-
Heidecke, C.D.1
Hensler, T.2
Weighardt, H.3
Zantl, N.4
Wagner, H.5
Siewert, J.R.6
Holzmann, B.7
-
50
-
-
0033976649
-
Relationships between T lymphocyte apoptosis and anergy following trauma
-
Pellegrini, J. D., De, A. K., Kodys, K., Puyana, J. C., Furse, R. K., and Miller-Graziano, C. (2000) Relationships between T lymphocyte apoptosis and anergy following trauma. J. Surg. Res. 88, 200-206
-
(2000)
J. Surg. Res.
, vol.88
, pp. 200-206
-
-
Pellegrini, J.D.1
De, A.K.2
Kodys, K.3
Puyana, J.C.4
Furse, R.K.5
Miller-Graziano, C.6
-
51
-
-
0030077878
-
Trauma-induced suppression of antigen presentation and expression of major histocompatibility class II antigen complex in leukocytes
-
Ayala, A., Ertel, W., and Chaudry, I. H. (1996) Trauma-induced suppression of antigen presentation and expression of major histocompatibility class II antigen complex in leukocytes. Shock 5, 79-90
-
(1996)
Shock
, vol.5
, pp. 79-90
-
-
Ayala, A.1
Ertel, W.2
Chaudry, I.H.3
-
52
-
-
0034604169
-
Apoptosis. Gone but not forgotten
-
Green, D. R., and Beere, H. M. (2000) Apoptosis. Gone but not forgotten. Nature (London) 405, 28-29
-
(2000)
Nature (London)
, vol.405
, pp. 28-29
-
-
Green, D.R.1
Beere, H.M.2
-
53
-
-
0031454570
-
Immunosuppressive effects of apoptotic cells
-
Voll, R. E., Herrmann, M., Roth, E. A., Stach, C., Kalden, J. R., and Girkontaite, I. (1997) Immunosuppressive effects of apoptotic cells. Nature (London) 390, 350-351
-
(1997)
Nature (London)
, vol.390
, pp. 350-351
-
-
Voll, R.E.1
Herrmann, M.2
Roth, E.A.3
Stach, C.4
Kalden, J.R.5
Girkontaite, I.6
-
54
-
-
0034604029
-
A receptor for phosphatidyl-serine-specific clearance of apoptotic cells
-
Fadok, V. A., Bratton, D. L., Rose, D. M., Pearson, A., Ezekewitz, R. A., and Henson, P. M. (2000) A receptor for phosphatidyl-serine-specific clearance of apoptotic cells. Nature (London) 405, 85-90
-
(2000)
Nature (London)
, vol.405
, pp. 85-90
-
-
Fadok, V.A.1
Bratton, D.L.2
Rose, D.M.3
Pearson, A.4
Ezekewitz, R.A.5
Henson, P.M.6
-
55
-
-
0035338993
-
Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans
-
Hotchkiss, R. S., Tinsley, K. W., Swanson, P. E., Schmieg, R. E., Jr., Hui, J. J., Chang, K. C., Osborne, D. F., Freeman, B. D., Cobb, J. P., Buchman, T. G., et al. (2001) Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans. J. Immunol. 166, 6952-6963
-
(2001)
J. Immunol.
, vol.166
, pp. 6952-6963
-
-
Hotchkiss, R.S.1
Tinsley, K.W.2
Swanson, P.E.3
Schmieg Jr., R.E.4
Hui, J.J.5
Chang, K.C.6
Osborne, D.F.7
Freeman, B.D.8
Cobb, J.P.9
Buchman, T.G.10
-
56
-
-
0036499162
-
Depletion of dendritic cells, but not macrophages, in patients with sepsis
-
Hotchkiss, R. S., Tinsley, K. W., Swanson, P. E., Grayson, M. H., Osborne, D. F., Wagner, T. H., Cobb, J. P., Coopersmith, C., and Karl, I. E. (2002) Depletion of dendritic cells, but not macrophages, in patients with sepsis. J. Immunol. 168, 2493-2500
-
(2002)
J. Immunol.
, vol.168
, pp. 2493-2500
-
-
Hotchkiss, R.S.1
Tinsley, K.W.2
Swanson, P.E.3
Grayson, M.H.4
Osborne, D.F.5
Wagner, T.H.6
Cobb, J.P.7
Coopersmith, C.8
Karl, I.E.9
-
57
-
-
0032519925
-
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF
-
Fadok, V. A., Bratton, D. L., Konowal, A., Freed, P. W., Westcott, J. Y., and Henson, P. M. (1998) Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J. Clin. Invest. 101, 890-898
-
(1998)
J. Clin. Invest
, vol.101
, pp. 890-898
-
-
Fadok, V.A.1
Bratton, D.L.2
Konowal, A.3
Freed, P.W.4
Westcott, J.Y.5
Henson, P.M.6
-
58
-
-
0033485401
-
Transcriptional and translational regulation of inflammatory mediator production by endogenous TGF-beta in macrophages that have ingested apoptotic cells
-
McDonald, P. P., Fadok, V. A., Bratton, D., and Henson, P. M. (1999) Transcriptional and translational regulation of inflammatory mediator production by endogenous TGF-beta in macrophages that have ingested apoptotic cells. J. Immunol. 163, 6164-6172
-
(1999)
J. Immunol.
, vol.163
, pp. 6164-6172
-
-
McDonald, P.P.1
Fadok, V.A.2
Bratton, D.3
Henson, P.M.4
-
59
-
-
0034960320
-
TGF-beta released by apoptotic T cells contributes to an immunosuppressive milieu
-
Chen, W., Frank, M. E., Jin, W., and Wahl, S. M. (2001) TGF-beta released by apoptotic T cells contributes to an immunosuppressive milieu. Immunity 14, 715-725
-
(2001)
Immunity
, vol.14
, pp. 715-725
-
-
Chen, W.1
Frank, M.E.2
Jin, W.3
Wahl, S.M.4
-
60
-
-
0342751267
-
Differential effects of necrotic or apoptotic cell uptake on antigen presentation by macrophages
-
Barker, R. N., Erwig, L., Pearce, W. P., Devine, A., and Rees, A. J. (1999) Differential effects of necrotic or apoptotic cell uptake on antigen presentation by macrophages. Pathobiology 67, 302-305
-
(1999)
Pathobiology
, vol.67
, pp. 302-305
-
-
Barker, R.N.1
Erwig, L.2
Pearce, W.P.3
Devine, A.4
Rees, A.J.5
-
61
-
-
0034614897
-
Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
-
Sauter, B., Albert, M. L., Francisco, L., Larsson, M., Somersan, S., and Bhardwaj, N. (2000) Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells. J. Exp. Med. 191, 423-434
-
(2000)
J. Exp. Med.
, vol.191
, pp. 423-434
-
-
Sauter, B.1
Albert, M.L.2
Francisco, L.3
Larsson, M.4
Somersan, S.5
Bhardwaj, N.6
-
62
-
-
0038312126
-
Adoptive transfer of apoptotic splenocytes worsens survival, whereas adoptive transfer of necrotic splenocytes improves survival in sepsis
-
Hotchkiss, R. S., Chang, K. C., Grayson, M. H., Tinsley, K. W., Dunne, B. S., Davis, C. G., Osborne, D. F., and Karl, I. E. (2003) Adoptive transfer of apoptotic splenocytes worsens survival, whereas adoptive transfer of necrotic splenocytes improves survival in sepsis. Proc. Natl. Acad. Sci. USA 100, 6724-6729
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 6724-6729
-
-
Hotchkiss, R.S.1
Chang, K.C.2
Grayson, M.H.3
Tinsley, K.W.4
Dunne, B.S.5
Davis, C.G.6
Osborne, D.F.7
Karl, I.E.8
-
63
-
-
0031110570
-
Cecal ligation and puncture (CLP) induces apoptosis in thymus, spleen, lung, and gut by an endotoxin and TNF-independent pathway
-
Hiramatsu, M., Hotchkiss, R. S., Karl, I. E., and Buchman, T. G. (1997) Cecal ligation and puncture (CLP) induces apoptosis in thymus, spleen, lung, and gut by an endotoxin and TNF-independent pathway. Shock 7, 247-253
-
(1997)
Shock
, vol.7
, pp. 247-253
-
-
Hiramatsu, M.1
Hotchkiss, R.S.2
Karl, I.E.3
Buchman, T.G.4
-
64
-
-
0036213419
-
Bacterial translocation and intestinal morphological findings in jaundiced rats
-
Sileri, P., Morini, S., Sica, G. S., Schena, S., Rastellini, C., Gaspari, A. L., Benedetti, E., and Cicalese, L. (2002) Bacterial translocation and intestinal morphological findings in jaundiced rats. Dig. Dis. Sci. 47, 929-934
-
(2002)
Dig. Dis. Sci.
, vol.47
, pp. 929-934
-
-
Sileri, P.1
Morini, S.2
Sica, G.S.3
Schena, S.4
Rastellini, C.5
Gaspari, A.L.6
Benedetti, E.7
Cicalese, L.8
-
65
-
-
0036417213
-
The role of poly(ADP-ribose) synthetase inhibition in preventing endotoxemia-induced intestinal epithelial apoptosis
-
Cinel, I., Buyukafsar, K., Cinel, L., Polat, A., Atici, S., Tamer, L., and Oral, U. (2002) The role of poly(ADP-ribose) synthetase inhibition in preventing endotoxemia-induced intestinal epithelial apoptosis. Pharmacol Res. 46, 119-127
-
(2002)
Pharmacol Res
, vol.46
, pp. 119-127
-
-
Cinel, I.1
Buyukafsar, K.2
Cinel, L.3
Polat, A.4
Atici, S.5
Tamer, L.6
Oral, U.7
-
66
-
-
0038805609
-
Intestinal epithelial regenerative capacity: An "Achilles' heel" in trauma/burn/sepsis injuries?
-
Sayeed, M. M. (2003) Intestinal epithelial regenerative capacity: an "Achilles' heel" in trauma/burn/sepsis injuries? Crit. Care Med. 31, 1864-1866
-
(2003)
Crit. Care Med.
, vol.31
, pp. 1864-1866
-
-
Sayeed, M.M.1
-
67
-
-
0037834561
-
Progress in clinical neurosciences: Sepsis-associated encephalopathy: Evolving concepts
-
Wilson, J. X., and Young, G. B. (2003) Progress in clinical neurosciences: sepsis-associated encephalopathy: evolving concepts. Can. J. Neurol. Sci. 30, 98-105
-
(2003)
Can. J. Neurol. Sci.
, vol.30
, pp. 98-105
-
-
Wilson, J.X.1
Young, G.B.2
-
68
-
-
0036065101
-
The natural history of venous thromboembolism: Impact on ventilation/perfusion scan reporting
-
Gray, H. W. (2002) The natural history of venous thromboembolism: impact on ventilation/perfusion scan reporting. Semin. Nucl. Med. 32, 159-172
-
(2002)
Semin. Nucl. Med.
, vol.32
, pp. 159-172
-
-
Gray, H.W.1
-
69
-
-
0036583312
-
The cardiovascular response in sepsis: Proposed mechanisms of the beneficial effect of adrenomedullin and its binding protein
-
Fowler, D. E., and Wang, P. (2002) The cardiovascular response in sepsis: proposed mechanisms of the beneficial effect of adrenomedullin and its binding protein (review). Int. J. Mol. Med. 9, 443-449
-
(2002)
Int. J. Mol. Med.
, vol.9
, pp. 443-449
-
-
Fowler, D.E.1
Wang, P.2
-
70
-
-
0037611384
-
Cellular apoptosis and organ injury in sepsis: A review
-
Power, C., Fanning, N., and Redmond, H. P. (2002) Cellular apoptosis and organ injury in sepsis: a review. Shock 18, 197-211
-
(2002)
Shock
, vol.18
, pp. 197-211
-
-
Power, C.1
Fanning, N.2
Redmond, H.P.3
-
71
-
-
0642283959
-
Targeting apoptosis in acute tubular injury
-
Oruz, A., Justo, P., Sanz, A., Lorz, C., and Egido, J. (2003) Targeting apoptosis in acute tubular injury. Biochem. Pharmacol. 66, 1589-1594
-
(2003)
Biochem. Pharmacol.
, vol.66
, pp. 1589-1594
-
-
Oruz, A.1
Justo, P.2
Sanz, A.3
Lorz, C.4
Egido, J.5
-
72
-
-
0029823055
-
Monocyte deactivation-rationale for a new therapeutic strategy in sepsis
-
Volk, H. D., Reinke, P., Krausch, D., Zuckermann, H., Asadullah, K., Muller, J. M., Docke, W. D., and Kox, W. J. (1996) Monocyte deactivation- rationale for a new therapeutic strategy in sepsis. Intensive Care Med. 22, Suppl. 4, S474-S481
-
(1996)
Intensive Care Med.
, vol.22
, Issue.SUPPL. 4
-
-
Volk, H.D.1
Reinke, P.2
Krausch, D.3
Zuckermann, H.4
Asadullah, K.5
Muller, J.M.6
Docke, W.D.7
Kox, W.J.8
-
73
-
-
0024555884
-
Enhanced cell-mediated protection against fatal Escherichia coli septicemia induced by treatment with recombinant IL-2
-
Goronzy, J., Weyand, C., Quan, J., Fathman, C. G., and O'Hanley, P. (1989) Enhanced cell-mediated protection against fatal Escherichia coli septicemia induced by treatment with recombinant IL-2. J. Immunol. 142, 1134-1138
-
(1989)
J. Immunol.
, vol.142
, pp. 1134-1138
-
-
Goronzy, J.1
Weyand, C.2
Quan, J.3
Fathman, C.G.4
O'Hanley, P.5
-
74
-
-
0030917203
-
Monocyte deactivation in septic patients: Restoration by IFN-gamma treatment
-
Docke, W. D., Randow, F., Syrbe, U., Krausch, D., Asadullah, K., Reinke, P., Volk, H. D., and Kox, W. (1997) Monocyte deactivation in septic patients: restoration by IFN-gamma treatment. Nat. Med. 3, 678-681
-
(1997)
Nat. Med.
, vol.3
, pp. 678-681
-
-
Docke, W.D.1
Randow, F.2
Syrbe, U.3
Krausch, D.4
Asadullah, K.5
Reinke, P.6
Volk, H.D.7
Kox, W.8
|