Subversion of a lysosomal pathway regulating neutrophil apoptosis by a major bacterial toxin, pyocyanin

Journal of Immunology

Volumn 180, Issue 5, 2008, Pages 3502-3511

  Prince, Lynne R ^a   Bianchi, Stephen M ^a   Vaughan, Kathryn M ^a   Bewley, Martin A ^a   Marriott, Helen M ^a   Walmsley, Sarah R ^a   Taylor, Graham W ^b   Buttle, David J ^a   Sabroe, Ian ^a   Dockrell, David H ^a   Whyte, Moira K B ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL TOXIN; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CATHEPSIN D; EXOTOXIN; PROTEIN MCL 1; PROTEINASE; PROTEINASE INHIBITOR; PYOCYANINE; CASPASE 3;

ACIDIFICATION; APOPTOSIS; ARTICLE; BACTERIAL TRANSLOCATION; CELL DEATH; CELL DISRUPTION; CELL FUNCTION; CELL MEMBRANE PERMEABILITY; CELL PERMEABILIZATION; CELL PH; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; DISEASE PREDISPOSITION; DRUG EFFECT; DRUG EXPOSURE; DRUG MECHANISM; ENZYME ACTIVATION; HOST RESISTANCE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; LYSOSOME; MITOCHONDRIAL MEMBRANE; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN STABILITY; CELL CULTURE; CELL SURVIVAL; DRUG ANTAGONISM; ENZYMOLOGY; IMMUNOLOGY; INTRACELLULAR FLUID; MICROBIOLOGY; OXIDATIVE STRESS; PATHOGENICITY; PATHOLOGY; PH; PHYSIOLOGY; PSEUDOMONAS AERUGINOSA; SECRETION; SIGNAL TRANSDUCTION;

APOPTOSIS; BACTERIAL TOXINS; CASPASE 3; CATHEPSIN D; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; HUMANS; HYDROGEN-ION CONCENTRATION; INTRACELLULAR FLUID; LYSOSOMES; NEUTROPHILS; OXIDATIVE STRESS; PSEUDOMONAS AERUGINOSA; PYOCYANINE; SIGNAL TRANSDUCTION;

EID: 49149125956     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.5.3502     Document Type: Article

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