P53-Dependent control of cell death by nicastrin: Lack of requirement for presenilin-dependent γ-secretase complex

Journal of Neurochemistry

Volumn 109, Issue 1, 2009, Pages 225-237

  Pardossi Piquard, Raphaëlle ^b   Dunys, Julie ^b   Giaime, Emilie ^b   Guillot Sestier, Marie Victoire ^b   St George Hyslop, Peter ^c   Checler, Frédéric ^a,b   Alves Da Costa, Cristine ^a,b  

^a INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b CNRS   (France)

^c TORONTO WESTERN HOSPITAL   (Canada)

Author keywords

secretase complex; Akt; Caspase 3; Knockout fibroblasts; Nicastrin; P53; Presenilins

Indexed keywords

CASPASE 3; GAMMA SECRETASE; NICASTRIN; PRESENILIN; PRESENILIN 1; PRESENILIN 2; PROTEIN P53; STAUROSPORINE; THAPSIGARGIN;

APOPTOSIS; ARTICLE; CELL STRAIN HEK293; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; NERVE CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMYLOID PRECURSOR PROTEIN SECRETASES; CELL DEATH; CELL LINE; CELL SURVIVAL; HUMANS; MEMBRANE GLYCOPROTEINS; PRESENILINS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 61849176021     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.05952.x     Document Type: Article

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