Targeting hypoxia-inducible factor-1 (HIF-1) signaling in therapeutics: Implications for the treatment of inflammatory Bowel disease

Recent Patents on Inflammation and Allergy Drug Discovery

Volumn 3, Issue 1, 2009, Pages 1-16

  Hirota, Simon A ^a   Beck, Paul L ^a   MacDonald, Justin A ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

CD73; Colitis; Crohn's disease; Hypoxia inducible factor; Inflammation; Inflammatory bowel disease; Intestinal trefoil factor; Prolyl hydroxylase; Vascular endothelial growth factor

Indexed keywords

5' NUCLEOTIDASE; DIMETHYLOXALYLGLYCINE; ENZYME INHIBITOR; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1 ANTAGONIST; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTESTINAL TREFOIL FACTOR; MESSENGER RNA; MUCIN 3; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANGIOGENESIS; COLORECTAL CANCER; DISEASE ASSOCIATION; DRUG EFFICACY; ENTERITIS; EYE INFLAMMATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HOMEOSTASIS; HUMAN; HYDROXYLATION; INFLAMMATION; INTERNAL RIBOSOME ENTRY SITE; INTESTINE MUCOSA PERMEABILITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; DRUG DELIVERY SYSTEM; DRUG EFFECT; GASTROINTESTINAL TRACT; GENE EXPRESSION REGULATION; METABOLISM; PATENT; PATHOPHYSIOLOGY;

ANIMALS; DRUG DELIVERY SYSTEMS; GASTROINTESTINAL TRACT; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; INFLAMMATORY BOWEL DISEASES; PATENTS AS TOPIC; SIGNAL TRANSDUCTION;

EID: 61449231910     PISSN: 1872213X     EISSN: None     Source Type: Journal    
DOI: 10.2174/187221309787158434     Document Type: Review

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