A novel thiol compound, N-acetylcysteine amide, attenuates allergic airway disease by regulating activation of NF-êB and hypoxia-inducible factor-1α

Experimental and Molecular Medicine

Volumn 39, Issue 6, 2007, Pages 756-768

  Kyung, Sun Lee ^a   So, Ri Kim ^a   Hee, Sun Park ^b   Seoung, Ju Park ^a   Kyung, Hoon Min ^a   Ka, Young Lee ^a   Yeong, Hun Choe ^a   Sang, Hyun Hong ^a   Hyo, Jin Han ^a   Young, Rae Lee ^a   Jong, Suk Kim ^a   Atlas, Daphne ^c   Yong, Chul Lee ^a  

^a Chonbuk National University Medical School   (South Korea)

^b Chungnam National University   (South Korea)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Hypoxia inducible factor 1, subunit; Lung inflammation; N acetylcysteinamide; NF B; Oxidative stress; Respiratory hypersensitivity

Indexed keywords

ACETYLCYSTEINE DERIVATIVE; CYTOKINE; GLUTATHIONE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; N ACETYLCYSTEINAMIDE; NUCLEAR PROTEIN; OVALBUMIN; REACTIVE OXYGEN METABOLITE; THIOL DERIVATIVE; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; VASCULOTROPIN;

AIRWAY RESISTANCE; ALLERGIC ASTHMA; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD VESSEL PERMEABILITY; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; MOLECULAR WEIGHT; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PATHOGENESIS; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT INFLAMMATION; TH2 CELL; TREATMENT OUTCOME; TREATMENT RESPONSE;

ANIMALIA; MUS;

EID: 38049153144     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2007.82     Document Type: Article

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