Surface expression, polarization, and functional significance of CD73 in human intestinal epithelia

Journal of Clinical Investigation

Volumn 99, Issue 11, 1997, Pages 2588-2601

  Strohmeier, Gregg R ^a,b,e   Lencer, Wayne I ^a,b   Patapoff, Thomas W ^d   Thompson, Linda F ^c   Carlson, Susan L ^a,b   Moe, Signa J ^a,b   Carnes, Denice K ^a,b   Mrsny, Randall J ^d   Madara, James L ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD UNIVERSITY   (United States)

^c GENENTECH INC   (United States)

^d Oklahoma Medical Research Institute   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Caveolae; Chloride secretion; Ecto 5' nucleotidase; Mucosal inflammation; Neutrophil epithelial interactions

Indexed keywords

ADENOSINE DERIVATIVE; ADENOSINE PHOSPHATE; ADENOSINE RECEPTOR; ALPHA,BETA METHYLENEADENOSINE DIPHOSPHATE; ECTO 5' NUCLEOTIDASE; GLYCOSYLPHOSPHATIDYLINOSITOL; PHOSPHOLIPASE C;

ANTIGEN EXPRESSION; APICAL MEMBRANE; ARTICLE; CELL SURFACE; CHLORIDE TRANSPORT; CONFOCAL MICROSCOPY; CROSS LINKING; ENTERITIS; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; INTESTINE EPITHELIUM CELL; LEUKOCYTE; POLARIZATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0030974182     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119447     Document Type: Article

References (50)

1. Yardley, J.H. 1986. Pathology of Idiopathic Inflammatory Bowel Disease and Relevance of Specific Cell Findings: an overview. In Recent Developments in the Therapy of Inflammatory Bowel Disease. J.H. Yardley, editor. Johns Hopkins, Baltimore, MD. 3-9.
2. Madara, J.L., T.W. Patapoff, B. Gillece-Castro, S.P. Colgan, C.A. Parkos, C. Delp, and R.J. Mrsny. 1993. 5′-Adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers. J. Clin. Invest. 91:2320-2325.
3. 2b adenosine receptor mediates cAMP responses to adenosine receptor agonists in human intestinal epithelia. J. Boil. Chem. 270:2387-2394.
4. Parton, R.G., and K. Simons. 1995. Digging into caveolae. Science (Wash. DC). 269:1398-1399.
5. Anderson, R.G. 1993. Caveolae: Where incoming and outgoing messengers meet. Proc. Natl Acad. Sci. USA. 90:10909-10913.
6. Burger, R.M., and J.M. Lowenstein. 1975. 5′-nucleotidase from smooth muscle of small intestine and from brain. Inhibition by nucleotides. Biochemistry. 14:2362-2366.
7. Frick, G.P., and J.M. Lowenstein. 1976. Studies of 5′-nucleotidase in the perfused rat heart including measurements of the enzyme in perfused skeletal muscle and liver. J. Biol. Chem. 251:6372-6378.
8. Thompson, L.F. 1991. 5′-Nucleotidase-an overview of the last three years. In Purine and Pyrimidine Metabolism in Man. R.A. Harkness, G.B. Elion, and N. Zöllner, editors. Plenum Press, New York. 145-150.
9. Williams, M. 1990. Adenosine and adenosine receptors. In The Receptors. D.B. Bylund, editor. Humana Press, Clifton, NJ. p. 196.
10. Madara, J.L., and K. Dharmsathaphorn. 1985. Occluding junction structure-function relationships in a cultured monolayer. J. Cell. Biol. 101:2124-2133.
11. Shapiro, M., J. Matthews, G. Hecht, C. Delp, and J.L. Madara. 1991. Stabilization of F-actin prevents cAMP-elicited Cl-secretion in T84 cells. J. Clin. Invest. 87:1903-1909.
12. Nash, S., J. Stafford, and J.L. Madara. 1987. Effects of polymorphonuclear leukocyte transmigration on barrier function of cultured intestinal epithelial monolayers. J. Clin. Invest. 80:1104-1113.
13. Parkos, C.A., S.P. Colgan, T.W. Liang, A. Nusrat, A.E. Bacarra, D.K. Carnes, and J.L. Madara. 1996. CD47 mediates post-adhesive events required for neutrophil migration across polarized intestinal epithelia. J. Cell Biol. 132: 437-450.
14. Lencer, W.I., S. Moe, P.A. Rufo, and J.L. Madara. 1995. Transcytosis of cholera toxin subunits across model human intestinal epithelia. Proc. Natl. Acad. Sci. USA. 92:10094-10098.
15. Kaoutzani, P., C.A. Parkos, C. Delp-Archer, and J.L. Madara. 1993. Isolation of plasma membrane fractions from the intestinal epithelial model T84. Am. J. Physiol. 264:C1327-C1335.
16. Gottardi, C.J., L.A. Dunbar, and M.J. Caplan. 1995. Biotinylation and assessment of membrane polarity: caveats and methodological concerns. Am. J. Physiol. 268:F285-F295.
17. Laemmli, U.K. 1970. Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature (Lond.). 227:680-685.
18. Towbin, H., T. Staehelin, and J. Gordon. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA. 76:4350-4354.
19. Lisanti, M.P., Z. Tang, and M. Sargiacomo. 1993. Caveolin forms a hetero-oligomeric protein complex that interacts with an apical GPI-linked protein: implications for the biogenesis of caveolae. J. Cell Biol. 123:595-604.
20. - secretion in a model intestinal epithelium induced by a neutrophil-derived secretagogue. J. Clin. Invest. 89:1938-1944.
21. Thomson, L.F., J.M. Ruedi, A. Glass, G. Moldenhauer, P. Moller, M.G. Low, M.R. Klemens, M. Massaia, and A.H. Lucas. 1990. Production and characterization of monoclonal antibodies to the glycosyl phosphatidylinositol-anchored lymphocyte differentiation antigen ecto-5′-nucleotidase (CD73). Tissue Antigens. 35:9-19.
22. Cohn, S.M., T.C. Simon, K.A. Roth, E.H. Birkenmeier, and J.I. Gordon. 1992. Use of transgenic mice to map cis-acting elements in the intestinal fatty acid binding protein gene (Fabpi) that control its cell lineage-specific and regional patterns of expression along the duodenal-colonic and crypt-villus axes of the gut epithelium. J. Cell Biol. 119:27-44.
23. Madara, J.L. 1990. Pathobiology of the intestinal epithelial barrier. Am. J. Pathology. 137:1273-1281.
24. Dharmsathaphorn, K., and J.L. Madara. 1990. Established intestinal cell lines as model systems for electrolyte transport studies. Methods Enzymol. 192: 354-389.
25. Coyne, K.E., S.E. Hall, E.S. Thompson, M.A. Arce, T. Kinoshita, T. Fujita, D.J. Anstee, W. Rosse, and D.M. Lublin. 1992. Mapping of epitopes, glycosylation sites, and complement regulatory domains in human decay accelerating factor. J. Immunol. 149:2906-2913.
26. Parkos, C.A., S.P. Colgan, A.E. Bacarra, A. Nusrat, C. Delp-Archer, S. Carlson, D.H.C. Su, and J.L. Madara. 1995. Intestinal epithelia (T84) possess basolateral ligands for CD11b/CD18-mediated neutrophil adherence. Am. J. Physiol. 268:C472-C479.
27. 7 mediates adhesion of T lymphocytes to epithelial cells. J. Immunol. 150:3459-3470.
28. Barrett, K.E., P.A. Huott, S.S. Shah, K. Dharmsathaphorn, and S.I. Wasserman. 1989. Differing effects of apical and basolateral adenosine on colonic epithelial cell line T84. Am. J. Physiol. 256:C197-C203.
29. Cerneus, D.P., E. Ueffing, G. Posthuma, G.J. Strous, and A. van der Ende. 1993. Detergent insolubility of alkaline phosphatase during biosynthetic transport and endocytosis. J. Biol. Chem. 268:3150-3155.
30. Brown, D.A., and J.K. Rose. 1992. Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. Cell. 68:533-544.
31. Mayor, S., and F.R. Maxfield. 1995. Insolubility and redistribution of GPI-anchored proteins at the cell surface after detergent treatment. Mol Biol. Cell. 6:929-944.
32. Rothberg, K.G., Y. Ying, F. Kolhouse, B.A. Kamen, and R.G.W. Anderson. 1990. The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway. J. Cell Biol. 110:637-649.
33. Parton, R.G., B. Joggerst, and K. Simons. 1994. Regulated internalization of caveolae. J. Cell Biol. 127:1199-1215.
34. Thompson, L.F., J.M. Ruedi, A. Glass, M.G. Low, and A.H. Lucas. 1989. Antibodies to 5′ nucleotidase (CD73), a glycosyl-phosphatidylinositol-anchored protein, cause human peripheral blood T cells to proliferate. J. Immunol. 143:1815-1821.
35. Lisanti, M.P., P.E. Scherer, J. Vidugiriene, Z. Tang, A. Hermanowski-Vosatka, Y. Tu, R.F. Cook, and M. Sargiacomo. 1994. Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease. J. Cell Biol. 126:111-126.
36. Rijnboutt, S., G. Jansen, G. Posthuma, J.B. Hynes, J.H. Schornagel, and G.J. Strous. 1996. Endocytosis of GPI-linked membrane folate receptor-α. J. Cell Biol. 132:35-47.
37. Fra, A.M., E. Williamson, K. Simons, and R.G. Parton. 1994. Detergentinsoluble glycolipid microdomains in lymphocytes in the absence of caveolae. J. Biol. Chem. 269:30745-30748.
38. Gandhi, R., M. Le Hir, and B. Kaissling. 1990. Immunolocalization of ecto-5′-nucleotidase in the kidney by a monoclonal antibody. Histochemistry. 95:165-174.
39. Headrick, J.P., and R.J. Willis. 1989. 5′-Nucleotidase activity and adenosine formation in stimulated, hypoxic and underperfused rat heart. Biochem. J. 261:541-550.
40. Richardson, P.J., S.J. Brown, E.M. Bailyes, and J.P. Luzio. 1987. Ectoenzymes control adenosine modulation of immunoisolated cholinergic synapses. Nature (Lond.). 327:232-234.
41. Misumi, Y., S. Ogata, K. Ohkubo, S. Hirose, and Y. Ikehara. 1990. Primary structure of human placental 5′-nucleotidase and identification of the glycolipid anchor in the mature form. Eur. J. Biochem. 191:563-569.
42. Naito, Y., and J.M. Lowenstein. 1981. 5′-Nucleotidase from rat heart. Biochemistry. 20:5188-5194.
43. Bailyes, E.M., M.A.J. Ferguson, C.A.L.S. Colaco, and J.P. Luzio. 1990. Inositol is a constituent of detergent-solubilized immunoaffinity-purified rat liver 5′-nucleotidase. Biochem. J. 265:907-909.
44. 2-adenosine receptor subtype. Mol. Endocrinol. 6:384-393.
45. Lisanti, M.P., and E. Rodriguez-Boulan. 1990. Glycophospholipid membrane anchoring provides clues to the mechanism of protein sorting in polarized epithelial cells. Trends Biochem. Sci. 15:113-118.
46. Simons, K., and A. Wandinger-Ness. 1990. Polarized sorting in epithelia. Cell. 62:207-210.
47. Plagemann, P.G.W., R.M. Wohlhueter, and C. Woffendin. 1988. Nucleoside and nucleobase transport in animal cells. Biochim. Biophys. Acta. 947: 405-443.
48. Keller, G., M.W. Siegel, and I.W. Caras. 1992. Endocytosis of glycophospholipid-anchored and transmembrane forms of CD4 by different endocytic pathways. EMBO J. 11:863-874.
49. Anderson, R.G.W. 1993. Plasmalemmal caveolae and GPI-anchored membrane proteins. Curr. Opin. Cell Biol. 5:647-652.
50. Schnitzer, J.E., J. Liu, and P. Oh. 1995. Endothelial caveolae have the molecular transport machinery for vesicle budding, docking, and fusion including VAMP, NSF, SNAP, annexins, and GTPases. J. Biol. Chem. 270:14399-14404.