Role of hypoxia-inducible factor-1α in hypoxia-induced expressions of IL-8, MMP-1 and MMP-3 in rheumatoid fibroblast-like synoviocytes

Rheumatology

Volumn 47, Issue 6, 2008, Pages 834-839

  Ahn, J K ^a   Koh, E M ^a   Cha, H S ^a   Lee, Y S ^b   Kim, J ^b   Bae, E K ^b   Ahn, K S ^b  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Samsung Medical Center   (South Korea)

Author keywords

Cytokines; Fibroblast like synoviocytes; Hypoxia; Hypoxia inducible factor 1 ; Matrix metalloproteinase; Rheumatoid arthritis

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 6; INTERLEUKIN 8; INTERSTITIAL COLLAGENASE; MESSENGER RNA; SMALL INTERFERING RNA; STROMELYSIN;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FIBROBLAST LIKE SYNOVIOCYTE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HYPOXIA; IN VITRO STUDY; JOINT DESTRUCTION; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; WESTERN BLOTTING;

ARTHRITIS, RHEUMATOID; CELL HYPOXIA; CELLS, CULTURED; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOENZYME TECHNIQUES; INTERLEUKIN-8; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 3; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SYNOVIAL MEMBRANE;

EID: 44849126662     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/ken086     Document Type: Article

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