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Volumn 181, Issue 9, 2008, Pages 6481-6490

Signaling through MyD88 regulates leukocyte recruitment after brain injury

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 18; INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; MYD88 PROTEIN, MOUSE; UNCLASSIFIED DRUG;

EID: 58749112026     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.9.6481     Document Type: Article
Times cited : (56)

References (80)
  • 1
    • 0037385159 scopus 로고    scopus 로고
    • Macrophages and microglia in central nervous system injury: Are they helpful or harmful?
    • Schwartz, M. 2003. Macrophages and microglia in central nervous system injury: are they helpful or harmful? J. Cereb. Blood Flow Metab. 23: 385-394. (Pubitemid 36403019)
    • (2003) Journal of Cerebral Blood Flow and Metabolism , vol.23 , Issue.4 , pp. 385-394
    • Schwartz, M.1
  • 2
    • 16244384670 scopus 로고    scopus 로고
    • Inflammatory-mediated injury and repair in the traumatically injured spinal cord
    • DOI 10.2174/1381612053507468
    • Jones, T. B., E. E. McDaniel, and P. G. Popovich. 2005. Inflammatory-mediated injury and repair in the traumatically injured spinal cord. Curr. Pharm. Des. 11: 1223-1236. (Pubitemid 40458268)
    • (2005) Current Pharmaceutical Design , vol.11 , Issue.10 , pp. 1223-1236
    • Jones, T.B.1    McDaniel, E.E.2    Popovich, P.G.3
  • 3
    • 9944237897 scopus 로고    scopus 로고
    • Role of the immune system in the maintenance of mouse facial motoneuron viability after nerve injury
    • Jones, K. J., C. J. Serpe, S. C. Byram, C. A. Deboy, and V. M. Sanders. 2005. Role of the immune system in the maintenance of mouse facial motoneuron viability after nerve injury. Brain Behav. Immun. 19: 12-19.
    • (2005) Brain Behav. Immun. , vol.19 , pp. 12-19
    • Jones, K.J.1    Serpe, C.J.2    Byram, S.C.3    Deboy, C.A.4    Sanders, V.M.5
  • 4
    • 17844392320 scopus 로고    scopus 로고
    • Cytokine and chemokine inter-regulation in the inflamed or injured CNS
    • DOI 10.1016/j.brainresrev.2004.12.007, Glial-Neuron Crosstalk in Neuroinflamation, Neurodegeneration and Neuroprotection
    • Owens, T., A. A. Babcock, J. M. Millward, and H. Toft-Hansen. 2005. Cytokine and chemokine inter-regulation in the inflamed or injured CNS. Brain Res. Brain Res. Rev. 48: 178-184. (Pubitemid 40585748)
    • (2005) Brain Research Reviews , vol.48 , Issue.2 , pp. 178-184
    • Owens, T.1    Babcock, A.A.2    Millward, J.M.3    Toft-Hansen, H.4
  • 5
    • 7744224673 scopus 로고    scopus 로고
    • Microglia and neuroinflammation: A pathological perspective
    • Streit, W. J., R. E. Mrak, and W. S. Griffin. 2004. Microglia and neuroinflammation: a pathological perspective. J. Neuroinflammation 1: 14.
    • (2004) J. Neuroinflammation , vol.1 , pp. 14
    • Streit, W.J.1    Mrak, R.E.2    Griffin, W.S.3
  • 6
    • 17844382673 scopus 로고    scopus 로고
    • Innate (inherent) control of brain infection, brain inflammation and brain repair: The role of microglia, astrocytes, "protective" glial stem cells and stromal ependymal cells
    • Hauwel, M., E. Furon, C. Canova, M. Griffiths, J. Neal, and P. Gasque. 2005. Innate (inherent) control of brain infection, brain inflammation and brain repair: the role of microglia, astrocytes, "protective" glial stem cells and stromal ependymal cells. Brain Res. Brain Res. Rev. 48: 220-233.
    • (2005) Brain Res. Brain Res. Rev. , vol.48 , pp. 220-233
    • Hauwel, M.1    Furon, E.2    Canova, C.3    Griffiths, M.4    Neal, J.5    Gasque, P.6
  • 7
    • 0036518997 scopus 로고    scopus 로고
    • Innate immunity: The Missing link in neuroprotection and neurodegeneration?
    • DOI 10.1038/nrn752
    • Nguyen, M. D., J. P. Julien, and S. Rivest. 2002. Innate immunity: the missing link in neuroprotection and neurodegeneration? Nat. Rev. Neurosci. 3: 216-227. (Pubitemid 135706591)
    • (2002) Nature Reviews Neuroscience , vol.3 , Issue.3 , pp. 216-227
    • Nguyen, M.D.1    Julien, J.-P.2    Rivest, S.3
  • 8
    • 0031887788 scopus 로고    scopus 로고
    • Inflammation in traumatic brain injury: Role of cytokines and chemokines
    • DOI 10.1023/A:1022453332560
    • Ghirnikar, R. S., Y. L. Lee, and L. F. Eng. 1998. Inflammation in traumatic brain injury: role of cytokines and chemokines. Neurochem Res. 23: 329-340. (Pubitemid 28109878)
    • (1998) Neurochemical Research , vol.23 , Issue.3 , pp. 329-340
    • Ghirnikar, R.S.1    Lee, Y.L.2    Eng, L.F.3
  • 9
    • 0032055288 scopus 로고    scopus 로고
    • Do chemokines mediate leukocyte recruitment in post-traumatic CNS inflammation?
    • Ransohoff, R. M., and M. Tani. 1998. Do chemokines mediate leukocyte recruitment in post-traumatic CNS inflammation? Trends Neurosci. 21: 154-159.
    • (1998) Trends Neurosci. , vol.21 , pp. 154-159
    • Ransohoff, R.M.1    Tani, M.2
  • 10
    • 0036935538 scopus 로고    scopus 로고
    • Detrimental and beneficial effects of injury-induced inflammation and cytokine expression in the nervous system
    • Stoll, G., S. Jander, and M. Schroeter. 2002. Detrimental and beneficial effects of injury-induced inflammation and cytokine expression in the nervous system. Adv. Exp. Med. Biol. 513: 87-113. (Pubitemid 36332404)
    • (2002) Advances in Experimental Medicine and Biology , vol.513 , pp. 87-113
    • Stoll, G.1    Jander, S.2    Schroeter, M.3
  • 13
    • 0036709090 scopus 로고    scopus 로고
    • Characterization of microglial responses to Staphylococcus aureus: Effects on cytokine, costimulatory molecule, and Toll-like receptor expression
    • DOI 10.1016/S0165-5728(02)00216-3, PII S0165572802002163
    • Kielian, T., P. Mayes, and M. Kielian. 2002. Characterization of microglial responses to Staphylococcus aureus: effects on cytokine, costimulatory molecule, and Toll-like receptor expression. J. Neuroimmunol. 130: 86-99. (Pubitemid 35239996)
    • (2002) Journal of Neuroimmunology , vol.130 , Issue.1-2 , pp. 86-99
    • Kielian, T.1    Mayes, P.2    Kielian, M.3
  • 14
    • 34247468864 scopus 로고    scopus 로고
    • Expression and distribution of Toll-like receptors in the brain during murine neurocysticercosis
    • Mishra, B. B., P. K. Mishra, and J. M. Teale. 2006. Expression and distribution of Toll-like receptors in the brain during murine neurocysticercosis. J. Neuroimmunol. 181: 46-56.
    • (2006) J. Neuroimmunol. , vol.181 , pp. 46-56
    • Mishra, B.B.1    Mishra, P.K.2    Teale, J.M.3
  • 19
    • 34247545017 scopus 로고    scopus 로고
    • Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke
    • DOI 10.1161/CIRCULATIONAHA.106.603431
    • Caso, J. R., J. M. Pradillo, O. Hurtado, P. Lorenzo, M. A. Moro, and I. Lizasoain. 2007. Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke. Circulation 115: 1599-1608. (Pubitemid 46648645)
    • (2007) Circulation , vol.115 , Issue.12 , pp. 1599-1608
    • Caso, J.R.1    Pradillo, J.M.2    Hurtado, O.3    Lorenzo, P.4    Moro, M.A.5    Lizasoain, I.6
  • 20
    • 38348999001 scopus 로고    scopus 로고
    • Toll-like receptor 2 contributes to glial cell activation and heme oxygenase-1 expression in traumatic brain injury
    • Park, C., I. H. Cho, D. Kim, E. K. Jo, S. Y. Choi, S. B. Oh, K. Park, J. S. Kim, and S. J. Lee. 2008. Toll-like receptor 2 contributes to glial cell activation and heme oxygenase-1 expression in traumatic brain injury. Neurosci. Lett. 431: 123-128.
    • (2008) Neurosci. Lett. , vol.431 , pp. 123-128
    • Park, C.1    Cho, I.H.2    Kim, D.3    Jo, E.K.4    Choi, S.Y.5    Oh, S.B.6    Park, K.7    Kim, J.S.8    Lee, S.J.9
  • 21
    • 34247566510 scopus 로고    scopus 로고
    • The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
    • O'Neill, L. A., and A. G. Bowie. 2007. The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat. Rev. Immunol. 7: 353-364.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 353-364
    • O'Neill, L.A.1    Bowie, A.G.2
  • 22
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira, S., and K. Takeda. 2004. Toll-like receptor signalling. Nat. Rev. Immunol. 4: 499-511.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 23
    • 0037066427 scopus 로고    scopus 로고
    • The danger model: A renewed sense of self
    • DOI 10.1126/science.1071059
    • Matzinger, P. 2002. The danger model: a renewed sense of self. Science 296: 301-305. (Pubitemid 34303674)
    • (2002) Science , vol.296 , Issue.5566 , pp. 301-305
    • Matzinger, P.1
  • 25
    • 33645322938 scopus 로고    scopus 로고
    • Toll-like receptors in central nervous system glial inflammation and homeostasis
    • Kielian, T. 2006. Toll-like receptors in central nervous system glial inflammation and homeostasis. J. Neurosci. Res. 83: 711-730.
    • (2006) J. Neurosci. Res. , vol.83 , pp. 711-730
    • Kielian, T.1
  • 26
    • 17644414137 scopus 로고    scopus 로고
    • The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy
    • Tanga, F. Y., N. Nutile-McMenemy, and J. A. DeLeo. 2005. The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy. Proc. Natl. Acad. Sci. USA 102: 5856-5861.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 5856-5861
    • Tanga, F.Y.1    Nutile-McMenemy, N.2    DeLeo, J.A.3
  • 28
    • 0034765498 scopus 로고    scopus 로고
    • Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: No requirement for proapoptotic interleukin-1β in neurodegeneration
    • Nguyen, M. D., J. P. Julien, and S. Rivest. 2001. Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1β in neurodegeneration. Ann. Neurol. 50: 630-639.
    • (2001) Ann. Neurol. , vol.50 , pp. 630-639
    • Nguyen, M.D.1    Julien, J.P.2    Rivest, S.3
  • 29
    • 2942555126 scopus 로고    scopus 로고
    • Innate immune reaction in response to seizures: Implications for the neuropathology associated with epilepsy
    • Turrin, N. P., and S. Rivest. 2004. Innate immune reaction in response to seizures: implications for the neuropathology associated with epilepsy. Neurobiol. Dis. 16: 321-334.
    • (2004) Neurobiol. Dis. , vol.16 , pp. 321-334
    • Turrin, N.P.1    Rivest, S.2
  • 30
    • 34250182782 scopus 로고    scopus 로고
    • Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury
    • Kigerl, K. A., W. Lai, S. Rivest, R. P. Hart, A. R. Satoskar, and P. G. Popovich. 2007. Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury. J. Neurochem. 102: 37-50.
    • (2007) J. Neurochem. , vol.102 , pp. 37-50
    • Kigerl, K.A.1    Lai, W.2    Rivest, S.3    Hart, R.P.4    Satoskar, A.R.5    Popovich, P.G.6
  • 31
    • 32344440522 scopus 로고    scopus 로고
    • Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease
    • Simard, A. R., D. Soulet, G. Gowing, J. P. Julien, and S. Rivest. 2006. Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease. Neuron 49: 489-502.
    • (2006) Neuron , vol.49 , pp. 489-502
    • Simard, A.R.1    Soulet, D.2    Gowing, G.3    Julien, J.P.4    Rivest, S.5
  • 32
    • 37049028157 scopus 로고    scopus 로고
    • Neuroprotective effects of resident microglia following acute brain injury
    • DOI 10.1002/cne.21469
    • Simard, A. R., and S. Rivest. 2007. Neuroprotective effects of resident microglia following acute brain injury. J. Comp. Neurol. 504: 716-729. (Pubitemid 350246584)
    • (2007) Journal of Comparative Neurology , vol.504 , Issue.6 , pp. 716-729
    • Simard, A.R.1    Rivest, S.2
  • 33
    • 37249011467 scopus 로고    scopus 로고
    • MyD88-deficient bone marrow cells accelerate onset and reduce survival in a mouse model of amyotrophic lateral sclerosis
    • DOI 10.1083/jcb.200705046
    • Kang, J., and S. Rivest. 2007. MyD88-deficient bone marrow cells accelerate onset and reduce survival in a mouse model of amyotrophic lateral sclerosis. J. Cell Biol. 179: 1219-1230. (Pubitemid 350277740)
    • (2007) Journal of Cell Biology , vol.179 , Issue.6 , pp. 1219-1230
    • Kang, J.1    Rivest, S.2
  • 35
    • 33750576993 scopus 로고    scopus 로고
    • Role of toll-like receptor signalling in Aβ uptake and clearance
    • DOI 10.1093/brain/awl249
    • Tahara, K., H. D. Kim, J. J. Jin, J. A. Maxwell, L. Li, and K. Fukuchi. 2006. Role of Toll-like receptor signalling in Aβ uptake and clearance. Brain 129: 3006-3019. (Pubitemid 44684521)
    • (2006) Brain , vol.129 , Issue.11 , pp. 3006-3019
    • Tahara, K.1    Kim, H.-D.2    Jin, J.-J.3    Maxwell, J.A.4    Li, L.5    Fukuchi, K.-I.6
  • 36
    • 45949106077 scopus 로고    scopus 로고
    • Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid β1-42 and delay the cognitive decline in a mouse model of Alzheimer's disease
    • Richard, K. L., M. Filali, P. Prefontaine, and S. Rivest. 2008. Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid β1-42 and delay the cognitive decline in a mouse model of Alzheimer's disease. J. Neurosci. 28: 5784-5793.
    • (2008) J. Neurosci. , vol.28 , pp. 5784-5793
    • Richard, K.L.1    Filali, M.2    Prefontaine, P.3    Rivest, S.4
  • 37
    • 36248934262 scopus 로고    scopus 로고
    • Toll-like receptor signaling is critical for Wallerian degeneration and functional recovery after peripheral nerve injury
    • DOI 10.1523/JNEUROSCI.3027-07.2007
    • Boivin, A., I. Pineau, B. Barrette, M. Filali, N. Vallieres, S. Rivest, and S. Lacroix. 2007. Toll-like receptor signaling is critical for Wallerian degeneration and functional recovery after peripheral nerve injury. J. Neurosci. 27: 12565-12576. (Pubitemid 350127805)
    • (2007) Journal of Neuroscience , vol.27 , Issue.46 , pp. 12565-12576
    • Boivin, A.1    Pineau, I.2    Barrette, B.3    Filali, M.4    Vallieres, N.5    Rivest, S.6    Lacroix, S.7
  • 40
    • 33751554878 scopus 로고    scopus 로고
    • A requirement for microglial TLR4 in leukocyte recruitment into brain in response to lipopolysaccharide
    • Zhou, H., B. M. Lapointe, S. R. Clark, L. Zbytnuik, and P. Kubes. 2006. A requirement for microglial TLR4 in leukocyte recruitment into brain in response to lipopolysaccharide. J. Immunol. 177: 8103-8110. (Pubitemid 44846329)
    • (2006) Journal of Immunology , vol.177 , Issue.11 , pp. 8103-8110
    • Zhou, H.1    Lapointe, B.M.2    Clark, S.R.3    Zbytnuik, L.4    Kubes, P.5
  • 42
    • 33947685006 scopus 로고    scopus 로고
    • MyD88-dependent signals are essential for the host immune response in experimental brain abscess
    • Kielian, T., N. K. Phulwani, N. Esen, M. M. Syed, A. C. Haney, K. McCastlain, and J. Johnson. 2007. MyD88-dependent signals are essential for the host immune response in experimental brain abscess. J. Immunol. 178: 4528-4537. (Pubitemid 46492405)
    • (2007) Journal of Immunology , vol.178 , Issue.7 , pp. 4528-4537
    • Kielian, T.1    Phulwani, N.K.2    Esen, N.3    Syed, M.M.4    Haney, A.C.5    McCastlain, K.6    Johnson, J.7
  • 43
    • 0041319041 scopus 로고    scopus 로고
    • Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS
    • Babcock, A. A., W. A. Kuziel, S. Rivest, and T. Owens. 2003. Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS. J. Neurosci. 23: 7922-7930.
    • (2003) J. Neurosci. , vol.23 , pp. 7922-7930
    • Babcock, A.A.1    Kuziel, W.A.2    Rivest, S.3    Owens, T.4
  • 45
    • 0034656415 scopus 로고    scopus 로고
    • IFN-γ enhances microglial reactions to hippocampal axonal degeneration
    • Jensen, M. B., I. V. Hegelund, N. D. Lomholt, B. Finsen, and T. Owens. 2000. IFN-γ enhances microglial reactions to hippocampal axonal degeneration. J. Neurosci. 20: 3612-3621.
    • (2000) J. Neurosci. , vol.20 , pp. 3612-3621
    • Jensen, M.B.1    Hegelund, I.V.2    Lomholt, N.D.3    Finsen, B.4    Owens, T.5
  • 46
    • 0031027062 scopus 로고    scopus 로고
    • Morphological and immunophenotypic microglial changes in the denervated fascia dentata of adult rats: Correlation with blood-brain barrier damage and astroglial reactions
    • Jensen, M. B., B. Finsen, and J. Zimmer. 1997. Morphological and immunophenotypic microglial changes in the denervated fascia dentata of adult rats: correlation with blood-brain barrier damage and astroglial reactions. Exp. Neurol. 143: 103-116.
    • (1997) Exp. Neurol. , vol.143 , pp. 103-116
    • Jensen, M.B.1    Finsen, B.2    Zimmer, J.3
  • 47
    • 0028203585 scopus 로고
    • Mechanisms of sprouting in the adult central nervous system: Cellular responses in areas of terminal degeneration and reinnervation in the rat hippocampus
    • Fagan, A. M., and F. H. Gage. 1994. Mechanisms of sprouting in the adult central nervous system: cellular responses in areas of terminal degeneration and reinnervation in the rat hippocampus. Neuroscience 58: 705-725.
    • (1994) Neuroscience , vol.58 , pp. 705-725
    • Fagan, A.M.1    Gage, F.H.2
  • 49
    • 0032127279 scopus 로고    scopus 로고
    • Targeted disruption of the MyD88 gene results in loss of IL-1- and IL- 18-mediated function
    • DOI 10.1016/S1074-7613(00)80596-8
    • Adachi, O., T. Kawai, K. Takeda, M. Matsumoto, H. Tsutsui, M. Sakagami, K. Nakanishi, and S. Akira. 1998. Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity 9: 143-150. (Pubitemid 28361303)
    • (1998) Immunity , vol.9 , Issue.1 , pp. 143-150
    • Adachi, O.1    Kawai, T.2    Takeda, K.3    Matsumoto, M.4    Tsutsui, H.5    Sakagami, M.6    Nakanishi, K.7    Akira, S.8
  • 50
    • 0027297663 scopus 로고
    • Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection
    • DOI 10.1016/0092-8674(93)90134-C
    • Pfeffer, K., T. Matsuyama, T. M. Kundig, A. Wakeham, K. Kishihara, A. Shahinian, K. Wiegmann, P. S. Ohashi, M. Kronke, and T. W. Mak. 1993. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 73: 457-467. (Pubitemid 23143346)
    • (1993) Cell , vol.73 , Issue.3 , pp. 457-467
    • Pfeffer, K.1    Matsuyama, T.2    Kundig, T.M.3    Wakeham, A.4    Kishihara, K.5    Shahinian, A.6    Wlegmann, K.7    Ohashi, P.S.8    Kronke, M.9    Mak, T.W.10
  • 53
    • 0033136775 scopus 로고    scopus 로고
    • Cutting edge: Generation of IL-18 receptor-deficient mice: Evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor
    • Hoshino, K., H. Tsutsui, T. Kawai, K. Takeda, K. Nakanishi, Y. Takeda, and S. Akira. 1999. Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor. J. Immunol. 162: 5041-5044. (Pubitemid 29307100)
    • (1999) Journal of Immunology , vol.162 , Issue.9 , pp. 5041-5044
    • Hoshino, K.1    Tsutsui, H.2    Kawai, T.3    Takeda, K.4    Nakanishi, K.5    Takeda, Y.6    Akira, S.7
  • 55
    • 0030691025 scopus 로고    scopus 로고
    • Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2
    • Kuziel, W. A., S. J. Morgan, T. C. Dawson, S. Griffin, O. Smithies, K. Ley, and N. Maeda. 1997. Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2. Proc. Natl. Acad. Sci. USA 94: 12053-12058.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12053-12058
    • Kuziel, W.A.1    Morgan, S.J.2    Dawson, T.C.3    Griffin, S.4    Smithies, O.5    Ley, K.6    Maeda, N.7
  • 56
    • 36148965872 scopus 로고    scopus 로고
    • Downregulation of membrane type-matrix metalloproteinases in the inflamed or injured central nervous system
    • DOI 10.1186/1742-2094-4-24
    • Toft-Hansen, H., A. A. Babcock, J. M. Millward, and T. Owens. 2007. Down-regulation of membrane type-matrix metalloproteinases in the inflamed or injured central nervous system J. Neuroinflammation 4: 24. (Pubitemid 350111695)
    • (2007) Journal of Neuroinflammation , vol.4 , pp. 24
    • Toft-Hansen, H.1    Babcock, A.A.2    Millward, J.M.3    Owens, T.4
  • 58
    • 0028983573 scopus 로고
    • TNF-α expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. Regulation by Th1 cytokines
    • Renno, T., M. Krakowski, C. Piccirillo, J. Y. Lin, and T. Owens. 1995. TNF-α expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. Regulation by Th1 cytokines. J. Immunol. 154: 944-953.
    • (1995) J. Immunol. , vol.154 , pp. 944-953
    • Renno, T.1    Krakowski, M.2    Piccirillo, C.3    Lin, J.Y.4    Owens, T.5
  • 59
    • 0025900245 scopus 로고
    • Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system
    • Sedgwick, J. D., S. Schwender, H. Imrich, R. Dorries, G. W. Butcher, and V. ter Meulen. 1991. Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system. Proc. Natl. Acad. Sci. USA 88: 7438-7442.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 7438-7442
    • Sedgwick, J.D.1    Schwender, S.2    Imrich, H.3    Dorries, R.4    Butcher, G.W.5    Ter Meulen, V.6
  • 60
    • 34250864496 scopus 로고    scopus 로고
    • Microglial recruitment, activation, and proliferation in response to primary demyelination
    • Remington, L. T., A. A. Babcock, S. P. Zehntner, and T. Owens. 2007. Microglial recruitment, activation, and proliferation in response to primary demyelination. Am. J. Pathol. 170: 1713-1724.
    • (2007) Am. J. Pathol. , vol.170 , pp. 1713-1724
    • Remington, L.T.1    Babcock, A.A.2    Zehntner, S.P.3    Owens, T.4
  • 61
    • 6344252618 scopus 로고    scopus 로고
    • Key metalloproteinases are expressed by specific cell types in experimental autoimmune encephalomyelitis
    • Toft-Hansen, H., R. K. Nuttall, D. R. Edwards, and T. Owens. 2004. Key metalloproteinases are expressed by specific cell types in experimental autoimmune encephalomyelitis. J. Immunol. 173: 5209-5218. (Pubitemid 39387804)
    • (2004) Journal of Immunology , vol.173 , Issue.8 , pp. 5209-5218
    • Toft-Hansen, H.1    Nuttall, R.K.2    Edwards, D.R.3    Owens, T.4
  • 62
    • 33746095375 scopus 로고    scopus 로고
    • Elevated interferon γ expression in the central nervous system of tumour necrosis factor receptor 1-deficient mice with experimental autoimmune encephalomyelitis
    • Wheeler, R. D., S. P. Zehntner, L. M. Kelly, L. Bourbonniere, and T. Owens. 2006. Elevated interferon γ expression in the central nervous system of tumour necrosis factor receptor 1-deficient mice with experimental autoimmune encephalomyelitis. Immunology 118: 527-538.
    • (2006) Immunology , vol.118 , pp. 527-538
    • Wheeler, R.D.1    Zehntner, S.P.2    Kelly, L.M.3    Bourbonniere, L.4    Owens, T.5
  • 66
    • 3042548183 scopus 로고    scopus 로고
    • Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes
    • Boule, M. W., C. Broughton, F. Mackay, S. Akira, A. Marshak-Rothstein, and I. R. Rifkin. 2004. Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes. J. Exp. Med. 199: 1631-1640.
    • (2004) J. Exp. Med. , vol.199 , pp. 1631-1640
    • Boule, M.W.1    Broughton, C.2    Mackay, F.3    Akira, S.4    Marshak-Rothstein, A.5    Rifkin, I.R.6
  • 69
    • 0037101634 scopus 로고    scopus 로고
    • The type 1 interleukin-1 receptor is essential for the efficient activation of microglia and the induction of multiple proinflammatory mediators in response to brain injury
    • Basu, A., J. K. Krady, M. O'Malley, S. D. Styren, S. T. DeKosky, and S. W. Levison. 2002. The type 1 interleukin-1 receptor is essential for the efficient activation of microglia and the induction of multiple proinflammatory mediators in response to brain injury. J. Neurosci. 22: 6071-6082. (Pubitemid 35387650)
    • (2002) Journal of Neuroscience , vol.22 , Issue.14 , pp. 6071-6082
    • Basu, A.1    Krady, J.K.2    O'Malley, M.3    Styren, S.D.4    Dekosky, S.T.5    Levison, S.W.6
  • 71
    • 0035882391 scopus 로고    scopus 로고
    • Induction of the proinflammatory cytokine interleukin-18 by axonal injury
    • DOI 10.1002/jnr.1158
    • Menge, T., S. Jander, and G. Stoll. 2001. Induction of the proinflammatory cytokine interleukin-18 by axonal injury. J. Neurosci. Res. 65: 332-339. (Pubitemid 32727035)
    • (2001) Journal of Neuroscience Research , vol.65 , Issue.4 , pp. 332-339
    • Menge, T.1    Jander, S.2    Stoll, G.3
  • 72
    • 0036137215 scopus 로고    scopus 로고
    • Interleukin-18 expression after focal ischemia of the rat brain: Association with the late-stage inflammatory response
    • Jander, S., M. Schroeter, and G. Stoll. 2002. Interleukin-18 expression after focal ischemia of the rat brain: association with the late-stage inflammatory response. J. Cereb. Blood Flow Metab. 22: 62-70. (Pubitemid 34038384)
    • (2002) Journal of Cerebral Blood Flow and Metabolism , vol.22 , Issue.1 , pp. 62-70
    • Jander, S.1    Schroeter, M.2    Stoll, G.3
  • 74
    • 33645101274 scopus 로고    scopus 로고
    • MyD88-mediated stabilization of interferon-γ-induced cytokine and chemokine mRNA
    • Sun, D., and A. Ding. 2006. MyD88-mediated stabilization of interferon-γ-induced cytokine and chemokine mRNA. Nat. Immunol. 7: 375-381.
    • (2006) Nat. Immunol. , vol.7 , pp. 375-381
    • Sun, D.1    Ding, A.2
  • 75
    • 33847175235 scopus 로고    scopus 로고
    • CCR5 expression on monocytes and T cells: Modulation by transmigration across the blood-brain barrier in vitro
    • Ubogu, E. E., M. K. Callahan, B. H. Tucky, and R. M. Ransohoff. 2006. CCR5 expression on monocytes and T cells: modulation by transmigration across the blood-brain barrier in vitro. Cell. Immunol. 243: 19-29.
    • (2006) Cell. Immunol. , vol.243 , pp. 19-29
    • Ubogu, E.E.1    Callahan, M.K.2    Tucky, B.H.3    Ransohoff, R.M.4
  • 76
    • 0030972777 scopus 로고    scopus 로고
    • Astrogliosis in the neonatal and adult murine brain post-trauma: Elevation of inflammatory cytokines and the lack of requirement for endogenous interferon-γ
    • Rostworowski, M., V. Balasingam, S. Chabot, T. Owens, and V. W. Yong. 1997. Astrogliosis in the neonatal and adult murine brain post-trauma: elevation of inflammatory cytokines and the lack of requirement for endogenous interferon-γ. J. Neurosci. 17: 3664-3674. (Pubitemid 27200593)
    • (1997) Journal of Neuroscience , vol.17 , Issue.10 , pp. 3664-3674
    • Rostworowski, M.1    Balasingam, V.2    Chabot, S.3    Owens, T.4    Yong, V.W.5
  • 77
    • 1942521774 scopus 로고    scopus 로고
    • Passive or active immunization with myelin basic protein impairs neurological function and exacerbates neuropathology after spinal cord injury in rats
    • Jones, T. B., D. P. Ankeny, Z. Guan, V. McGaughy, L. C. Fisher, D. M. Basso, and P. G. Popovich. 2004. Passive or active immunization with myelin basic protein impairs neurological function and exacerbates neuropathology after spinal cord injury in rats. J. Neurosci. 24: 3752-3761.
    • (2004) J. Neurosci. , vol.24 , pp. 3752-3761
    • Jones, T.B.1    Ankeny, D.P.2    Guan, Z.3    McGaughy, V.4    Fisher, L.C.5    Basso, D.M.6    Popovich, P.G.7
  • 79
    • 0242556891 scopus 로고    scopus 로고
    • Toll-like receptors: Balancing host resistance with immune tolerance
    • DOI 10.1016/j.coi.2003.09.002
    • Pasare, C., and R. Medzhitov. 2003. Toll-like receptors: balancing host resistance with immune tolerance. Curr. Opin. Immunol. 15: 677-682. (Pubitemid 37441304)
    • (2003) Current Opinion in Immunology , vol.15 , Issue.6 , pp. 677-682
    • Pasare, C.1    Medzhitov, R.2


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