The type 1 interleukin-1 receptor is essential for the efficient activation of microglia and the induction of multiple proinflammatory mediators in response to brain injury

Journal of Neuroscience

Volumn 22, Issue 14, 2002, Pages 6071-6082

  Basu, Anirban ^a,b   Krady, J Kyle ^a,b   O'Malley, Mark ^a,b   Styren, Scott D ^a,b   DeKosky, Steven T ^a,b   Levison, Steven W ^a,b  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Astrocytes; Cytokines; IL 1; IL 6; Null mutant mice; Prostaglandins; TNF ; Traumatic brain injury

Indexed keywords

CYCLOOXYGENASE 2; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 6; MESSENGER RNA; NERVE GROWTH FACTOR; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; BRAIN INJURY; BRAIN TISSUE; CELL ACTIVATION; CELL DEATH; CELL STRUCTURE; CONTROLLED STUDY; DISEASE ASSOCIATION; INFLAMMATION; MACROPHAGE; MALE; MICROGLIA; MOUSE; MULTIPLE SCLEROSIS; NERVE CELL; NERVE DEGENERATION; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STROKE; TISSUE INJURY;

EID: 0037101634     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-14-06071.2002     Document Type: Article

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