Phenotypic and Functional Characterization of Mice That Lack the Type I Receptor for IL-1

Journal of Immunology

Volumn 159, Issue 7, 1997, Pages 3364-3371

  Glaccum, Moira B ^a   Stocking, Kim L ^a   Charrier, Keith ^a   Smith, Jeffrey L ^a   Willis, Cindy R ^a   Maliszewski, Charles ^a   Livingston, David J ^b   Peschon, Jacques J ^a   Morrissey, Philip J ^a  

^a AMGEN INC   (United States)

^b VERTEX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE PHASE PROTEIN; CYSTEINE PROTEINASE; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; LIPOPOLYSACCHARIDE;

ANIMAL; ARTICLE; BIOSYNTHESIS; BLOOD; C57BL MOUSE; DISEASE PREDISPOSITION; FEMALE; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; LISTERIOSIS; MALE; MOUSE; MOUSE MUTANT; PHENOTYPE; PHYSIOLOGY;

ACUTE-PHASE PROTEINS; ANIMALS; CASPASE 1; CYSTEINE ENDOPEPTIDASES; DISEASE SUSCEPTIBILITY; FEMALE; IMMUNITY, NATURAL; INTERLEUKIN-1; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; LISTERIA INFECTIONS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHENOTYPE; RECEPTORS, INTERLEUKIN-1;

EID: 0031252311     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Dinarello, C. A. 1994. The biological properties of interleukin-1. Eur. Cytokine Netw. 5:533.
2. Sims, J. E., and S. K. Dower. 1994. Interleukin-1 receptors. Eur. Cytokine Netw. 5:539.
3. Kobayashi, Y., K. Yamamoto, T. Saido, H. Kawasaki, J. J. Openheim, and K. Matsushima. 1990. Identification of a calcium-activated neutral protease as a processing enzyme of human interleukin 1α. Proc. Natl. Acad. Sci. USA 87:5548.
4. Black, R. A., S. R. Kronheim, M. Cantrell, M. Deeley, C. J. March, K. S. Prickett, J. Wignall, P. J. Conlon, D. Cosman, T. P. Hopp, and D. Y. Mochizuki. 1988. Generation of biologically active interleukin-1β by proteolytic cleavage of the inactive precursor. J. Biol. Chem. 263:9437.
5. Cerretti, D. P., C. J. Kozlosky, B. Moseley, N. Nelson, N. K. Van, T. A. Greenstreet, C. J. March, S. R. Kronheim, T. Druck, L. A. Cannizzaro, K. Huebner, and R. A. Black. 1992. Molecular cloning of the IL-1β converting enzyme. Science 256:97.
6. Arend, W. P., M. Malyak, M. F. Smith, T. D. Whisenand, J. L. Slack, J. E. Sims, J. G. Giri, and S. K. Dower. 1994. Binding of IL-1α. IL-1β, and IL-1 receptor antagonist by soluble IL-1 receptors and levels of soluble IL-1 receptors in synovial fluids. J. Immunol. 153:4766.
7. Sims, J. E., M. A. Gayle, J. L. Slack, M. R. Alderson, T. A. Bird, J. G. Giri, F. Colotta, F. Re, A. Mantovani, K. Shanebeck, K. H. Grabstein, and S. K. Dower. 1993. Interleukin-1 signaling occurs exclusively via the type I receptor. Proc. Natl. Acad. Sci. USA 90:6155.
8. Cololta, F., S. K. Dower, J. E. Sims, and A. Mantovani. 1994. The type II "decoy" receptor: a novel regulatory pathway for interleukin 1. Immunol. Today 15:562.
9. Sims, J. E., J. G. Giri, and S. K. Dower. 1994. The two interleukin-1 receptors play different roles in IL-1 actions. Clin. Immunol. Immunopathol. 72:9.
10. Arend, W. P. 1993. Interleukin-1 receptor antagonist. Adv. Immunol. 54:167.
11. Slack, J., C. J. McMahan, S. Waugh, K. Schooley, M. K. Spriggs, J. E. Sims, and S. K. Dower. 1993. Independent binding of interleukin-1 alpha and interleukin-1 beta to type I and type II interleukin-1 receptors. J. Biol. Chem. 268:2513.
12. Dinarello, C. A. 1992. Role of interleukin-1 in infectious diseases. Immunol. Rev. 127:119.
13. Liu, Z., and C. Cheers. 1995. Interaction of interleukin-6, tumour necrosis factor and interleukin-1 during Listeria infection. Immunology 85:562.
14. van der Meer, J. W., M. T. Vogels, and B. J. Kullberg. 1994. Interleukin-1 and related pro-inflammatory cytokines in the treatment of bacterial infections in neutropenic and non-neutropenic animals. Biotherapy 7:161.
15. Sims, J. E., C. J. March, D. Cosman, M. B. Widmer, H. R. MacDonald, C. J. McMahan, C. E. Grubin, J. M. Wignall, J. L. Jackson, S. M. Call, D. Friend, A. R. Alpert, S. Gillis, D. L. Urdal, and S. K. Dower. 1988. cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily. Science 241:585.
16. McMahon, A. P., and A. Bradley. 1990. The Wnt-1 (inf-1) proto-oncogene is required for development of a large region of the mouse brain. Cell 62:1073.
17. Kuida, K., J. A. Lippke, G. Ku, M. W. Harding, D. J. Livingston, M. S.-S. Su, R. A. Flavell. 1995. Altered cytokine export and apoptosis in mice deficient in interleukin-1β converting enzyme. Science 267:2000.
18. Casano, F. J., A. M. Rolando, J. S. Mudgett, and S. M. Molineaux. 1994. the structure and complete nucleotide sequence of the murine gene encoding interleukin-1β converting enzyme (ICE). Genomics 20:474.
19. Maliszewski, C. R., P. J. Morrissey, W. C. Fanslow, T. A. Sato, C. Willis, and B. Davison. 1992. Delayed allograft rejection in mice transgenic for a soluble form of the IL-4 receptor. Cell. Immunol. 143:434.
20. + T cell-deficient mice survive inoculation with high doses of vaccinia virus and exhibit altered IgG responses. Proc. Natl. Acad. Sci. USA 89:6070.
21. Grabstein, K. H., J. Eisenman, D. Mochizuki, K. Shanebeck, P. Conlon, T. Hopp, C. March, and S. Gillis. 1986. Purification to homogeneity of B cell stimulating factor: a molecule that stimulates proliferation of multiple lymphokine-dependent cell lines. J. Exp. Med. 163:1405.
22. Howard, M., S. B. Mizel, L. Lachman, J. Ansel, B. Johnson, and W. E. Paul. 1983. Role of interleukin 1 in anti-immunoglobulin induced B cell proliferation. J. Exp. Med. 157:1529.
23. Li, P . H. Allen, S. Banerjee, S. Franklin, L. Herzog, C. Johnston, J. McDowell, M. Paskind, L. Rodman, J. Salfeld, E. Towne, D. Tracey, S. Wardwell, F.-Y. Wei, W. Wong, R. Kamen, and T. Seshadri. 1995. Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock. Cell 80:401.
24. Baumann, H., and J. Gauldie. 1994. The acute phase response. Immunol. Today 15:74.
25. Cheers, C., and I. F. C. McKenzie. 1980. A single gene (Lr) controlling resistance to murine listeriosis. In Genetic Control of Natural Resistance to Infection and Malignancy. E. Skamene, P. A. L. Kongshavn, and M. Landy, eds. Academic Press, New York, p. 141.
26. Durum, S. K., J. A. Schmidt, and J. J. Openheim. 1985. Interleukin 1: An immunological perspective. Annu. Rev. Immunol. 3:263.
27. Mizel, S. B. 1987. Interleukin 1 and T cell activation. Immunol. Today 8:330.
28. Staruck, M. J., and D. D. Wood. 1983. The adjuvanticity of interleukin 1 in vivo. J. Immunol. 130:2191.
29. Reed, S. G., D. L. Pihl, P. J. Conlon, and K. H. Grabstein. 1989. IL-1 as an adjuvant: role of T cells in the augmentation of specific antibody production by recombinant IL-1α. J. Immunol. 142:3129.
30. Leon, L. R., C. A. Conn, M. Glaccum, and M. J. Kluger. 1996. IL-1 type I receptor mediates acute phase reponse to turpentine, but not lipopolysaccharide, in mice. Am. J. Physiol. 271:R1668.
31. Klemenz, R., S. Hoffman, and A. K. Wereskiold. 1989. Serum and oncoprotein mediated induction of a gene with sequence similarity Io the gene encoding carcinoembryonic antigen. Proc. Natl. Acad. Sci. USA 86:5708.
32. Tominaga, S. 1989. A putative protein of a growth specific cDNA from BALB/c 3T3 cells is highly similar to the extracellular portion of mouse interleukin-1 receptor. FEBS Lett. 318:83.
33. Greenfeder, S. A., P. Nunes, L. Kwee, M. Labow, R. A. Chizzonite, and G. Ju. 1995. Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex. J. Biol. Chem. 270:13757.
34. Parnet, P., K. E. Garka, T. P. Bonnert, S. K. Dower, and J. E. Sims. 1996. IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor. J. Biol. Chem. 271:3967.
35. Gayle, M. A., J. E. Slack, T. P. Bonnert, B. R. Renshaw, G. Sonoda, T. Taguchi, J. R. Testa,. S. K. Dower, and J. E. Sims. 1996. Cloning of a putative receptor for the T1/ST2 receptor. J. Biol. Chem. 271:5784.
36. Zheng, H., D. Fletcher, W. Kozak, M. Jiang, K. J. Hofmann, C. A. Conn, D. Soszynski, C. Grabiec, M. E. Trumbauer, A. Shaw, M. J. Kostura, K. Stevens, H. Rosen, R. J. North, H. Y. Chen, M. J. Tocci, M. J. Kluger, and L. H. T. Van der Ploeg. 1995. Resistance to fever induction and impaired acute-phase response in interleukin-1β-deficient mice. Immunity 3:9.
37. Kopf, M.. H. Baumann, G. Freer, M. Freudenberg, M. Lamers, T. Kishimoto, R. Zinkernagel, H. Bluethmann, and G. Kohler. 1994. Impaired immune and acute phase responses in interleukin-6-deficient mice. Nature 368:339.
38. Fattori, E., M. Cappelleiti, P. Costa, C. Sellitto, L. Cantoni, M. Carelli, R. Faggioni, G. Fantuzzi, P. Ghezzi, and V. Poli. 1994. Defective inflammatory response in interleukin 6-dclicient mice. J. Exp. Med. 180:1243.
39. Car, B. D., V. M. Eng, B. Schynder, L. Ozmen, S. Huang, P. Gallay, D. Heumann, M. Aguet, and B. Ryffel. 1994. Interferon γ receptor deficient mice are resistant to endotoxic shock. J. Exp. Med. 179:1437.
40. Pfeffer, K., T. Matsuyama, T. M. Kundig, A. Wakeham, K. Kishihara, A. Shahinian, K. Wiegmann, P. S. Ohashi, M. Kronke, and T. W. Mak. 1993. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monacytogenes infection. Cell 73:457.
41. Rothe, J., W. Lesslauer, H. Lotscher, Y. Lang, P. Koebel, F. Kontgen, A. Althage, R. Zinkernagel, M. Steinmetz, and H. Bluethmann. 1993. Mice lacking the tumor necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes. Nature 364:798.
42. Gu, Y., K. Kuida, H. Tsutsui, G. Ku, K. Hsiao, M. A. Fleming, N. Hayashi, K. Higashino, H. Okamura, K. Nakanishi, M. Kurimoto, T. Tanimoto, R. A. Flavell, V. Sato, M. W. Harding, D. J. Livingston, and M. S.-S. Su. 1996. Activation of imerferon-γ inducing factor mediated by interleukin-1β converting enzyme. Science 275:206.
43. Hirsch, E., V. M. Irikura, S. M. Paul, and D. Hirsh. 1996. Functions of interleukin 1 receptor antagonist in gene knockout and overproducing mice. Proc. Natl. Acad. Sci. USA 93:11008.