-
1
-
-
0033966411
-
Toll signaling pathways in the innate immune response
-
Anderson, K. V. Toll signaling pathways in the innate immune response. Curr. Opin. Immunol. 12, 13-19 (2000).
-
(2000)
Curr. Opin. Immunol.
, vol.12
, pp. 13-19
-
-
Anderson, K.V.1
-
2
-
-
0033557176
-
Toll, a new piece in the puzzle of innate immunity
-
Wright, S. D. Toll, a new piece in the puzzle of innate immunity. J. Exp. Med. 189, 605-609 (1999).
-
(1999)
J. Exp. Med
, vol.189
, pp. 605-609
-
-
Wright, S.D.1
-
3
-
-
0034886143
-
Toll-like receptors: Critical proteins linking innate and acquired immunity
-
Akira, S., Takeda, K. & Kaisho, T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nature Immunol. 2, 675-680 (2001).
-
(2001)
Nature Immunol
, vol.2
, pp. 675-680
-
-
Akira, S.1
Takeda, K.2
Kaisho, T.3
-
4
-
-
0033844166
-
Toll-like receptors: A growing family of immune receptors that are differentially expressed and regulated by different leukocytes
-
Muzio, M., Polentarutti, N., Bosisio, D., Prahladan, M. K. & Mantovani, A. Toll-like receptors: a growing family of immune receptors that are differentially expressed and regulated by different leukocytes. J. Leukoc. Biol. 67, 450-456 (2000).
-
(2000)
J. Leukoc. Biol
, vol.67
, pp. 450-456
-
-
Muzio, M.1
Polentarutti, N.2
Bosisio, D.3
Prahladan, M.K.4
Mantovani, A.5
-
5
-
-
0033952703
-
Tlr4: Central component of the sole mammalian LPS sensor
-
Beutler, B. Tlr4: central component of the sole mammalian LPS sensor. Curr. Opin. Immunol. 12, 20-26 (2000).
-
(2000)
Curr. Opin. Immunol
, vol.12
, pp. 20-26
-
-
Beutler, B.1
-
6
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak, A. et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282, 2085-2088 (1998).
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
-
7
-
-
0033213590
-
Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components
-
Takeuchi, O. et al. Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components. Immunity 11, 443-451 (1999).
-
(1999)
Immunity
, vol.11
, pp. 443-451
-
-
Takeuchi, O.1
-
8
-
-
0035953543
-
The innate immune response to bacterial flagellin is mediated by Toll-like receptor
-
Hayashi, F. et al. The innate immune response to bacterial flagellin is mediated by Toll-like receptor. Nature 410, 1099-1103 (2001).
-
(2001)
Nature
, vol.410
, pp. 1099-1103
-
-
Hayashi, F.1
-
9
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi, H. et al. A Toll-like receptor recognizes bacterial DNA. Nature 408, 740-745 (2000).
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
-
10
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF- κB by Toll-like receptor
-
Alexopoulou, L., Holt, A. C., Medzhitov, R. & Flavell, R. A. Recognition of double-stranded RNA and activation of NF- κB by Toll-like receptor. Nature 413, 732-738 (2001).
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
11
-
-
0034610291
-
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors
-
Ozinsky, A. et al. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors. Proc. Natl Acad. Sci. USA 97, 13766-13771 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 13766-13771
-
-
Ozinsky, A.1
-
12
-
-
0033257795
-
JNK2 and IKKβ are required for activating the innate response to viral infection
-
Chu, W. M. et al. JNK2 and IKKβ are required for activating the innate response to viral infection. Immunity 11, 721-731 (1999).
-
(1999)
Immunity
, vol.11
, pp. 721-731
-
-
Chu, W.M.1
-
13
-
-
0033537719
-
Positive and negative regulation of I κB kinase activity through IKKβ subunit phosphorylation
-
Delhase, M., Hayakawa, M., Chen, Y & Karin, M. Positive and negative regulation of I κB kinase activity through IKKβ subunit phosphorylation. Science 284, 309-313 (1999).
-
(1999)
Science
, vol.284
, pp. 309-313
-
-
Delhase, M.1
Hayakawa, M.2
Chen, Y.3
Karin, M.4
-
14
-
-
0033537767
-
Abnormal morphogenesis but intact IKK activation in mice lacking the IKKα subunit of IκB kinase
-
Hu, Y. et al. Abnormal morphogenesis but intact IKK activation in mice lacking the IKKα subunit of IκB kinase. Science 284, 316-320 (1999).
-
(1999)
Science
, vol.284
, pp. 316-320
-
-
Hu, Y.1
-
15
-
-
0031683603
-
The bacterial endotoxin lipopolysaccharide has the ability to target the brain in upregulating its membrane CD14 receptor within specific cellular populations
-
Lacroix, S., Feinstein, D. & Rivest, S. The bacterial endotoxin lipopolysaccharide has the ability to target the brain in upregulating its membrane CD14 receptor within specific cellular populations. Brain Pathol. 8, 625-640 (1998).
-
(1998)
Brain Pathol
, vol.8
, pp. 625-640
-
-
Lacroix, S.1
Feinstein, D.2
Rivest, S.3
-
16
-
-
0035170282
-
Toll-like receptor 4: The missing link of the cerebral innate immune response triggered by circulating Gram-negative bacterial cell wall components
-
Laflamme, N. & Rivest, S. Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating Gram-negative bacterial cell wall components. FASEB J. 15, 155-163 (2001).
-
(2001)
FASEB J
, vol.15
, pp. 155-163
-
-
Laflamme, N.1
Rivest, S.2
-
17
-
-
0034765855
-
Circulating cell wall components derived from Gram-negative and not Gram- positive bacteria cause a profound transcriptional activation of the gene encoding toll-like receptor 2 in the CNS
-
Laflamme, N., Souci, G. & Rivest, S. Circulating cell wall components derived from Gram-negative and not Gram- positive bacteria cause a profound transcriptional activation of the gene encoding toll-like receptor 2 in the CNS. J. Neurochem. 70, 648-657 (2001).
-
(2001)
J. Neurochem.
, vol.70
, pp. 648-657
-
-
Laflamme, N.1
Souci, G.2
Rivest, S.3
-
18
-
-
0033568068
-
Neuronal activity and transcription of proinflammatory cytokines, IκBα, and iNOS in the mouse brain during acute endotoxemia and chronic infection with Trypanosoma brucei brucei
-
Brochu, S., Olivier, M. & Rivest, S. Neuronal activity and transcription of proinflammatory cytokines, IκBα, and iNOS in the mouse brain during acute endotoxemia and chronic infection with Trypanosoma brucei brucei. J. Neurosci. Res. 57, 801-816 (1999).
-
(1999)
J. Neurosci. Res
, vol.57
, pp. 801-816
-
-
Brochu, S.1
Olivier, M.2
Rivest, S.3
-
19
-
-
0032952972
-
Regulation of the gene encoding tumor necrosis factor α in the rat brain and pituitary in response to different models of systemic immune challenge
-
Nadeau, S. & Rivest, S. Regulation of the gene encoding tumor necrosis factor α in the rat brain and pituitary in response to different models of systemic immune challenge. J. Neuropathol. Exp. Neurol. 58, 61-77 (1999).
-
(1999)
J. Neuropathol. Exp. Neurol.
, vol.58
, pp. 61-77
-
-
Nadeau, S.1
Rivest, S.2
-
20
-
-
0034193376
-
Role of microglial-derived tumor necrosis factor in mediating CD14 transcription and NF-kB activity in the brain during endotoxemia
-
Nadeau, S. & Rivest, S. Role of microglial-derived tumor necrosis factor in mediating CD14 transcription and NF-kB activity in the brain during endotoxemia. J. Neurosci. 20, 3456-3468 (2000).
-
(2000)
J. Neurosci.
, vol.20
, pp. 3456-3468
-
-
Nadeau, S.1
Rivest, S.2
-
21
-
-
0035377576
-
The complement system is an integrated part of the natural innate immune response in the brain
-
Nadeau, S. & Rivest, S. The complement system is an integrated part of the natural innate immune response in the brain. FASEB J. 15, 1410-1412 (2001).
-
(2001)
FASEB J
, vol.15
, pp. 1410-1412
-
-
Nadeau, S.1
Rivest, S.2
-
22
-
-
0032031630
-
Time course and localization patterns of interleukin-1 β mRNA expression in the brain and pituitary after peripheral administration of lipopolysaccharide
-
Quan, N., Whiteside, M. & Herkenham, M. Time course and localization patterns of interleukin-1 β mRNA expression in the brain and pituitary after peripheral administration of lipopolysaccharide. Neuroscience 83, 281-293 (1997).
-
(1997)
Neuroscience
, vol.83
, pp. 281-293
-
-
Quan, N.1
Whiteside, M.2
Herkenham, M.3
-
23
-
-
0035844702
-
Regulation of the gene encoding the monocyte chemoattractant protein 1 (MCP-1) in the mouse and rat brain in response to circulating LPS and proinflammatory cytokines
-
Thibeault, I., Laflamme, N. & Rivest, S. Regulation of the gene encoding the monocyte chemoattractant protein 1 (MCP-1) in the mouse and rat brain in response to circulating LPS and proinflammatory cytokines. J. Comp. Neurol. 434, 461-477 (2001).
-
(2001)
J. Comp. Neurol
, vol.434
, pp. 461-477
-
-
Thibeault, I.1
Laflamme, N.2
Rivest, S.3
-
24
-
-
0030829208
-
Role of tumor necrosis factor a in induction of murine CD14 gene expression by lipopolysaccharide
-
Fearns, C. & Loskutoff, D. J. Role of tumor necrosis factor a in induction of murine CD14 gene expression by lipopolysaccharide. Infect. Immun. 65, 4822-4831 (1997).
-
(1997)
Infect. Immun
, vol.65
, pp. 4822-4831
-
-
Fearns, C.1
Loskutoff, D.J.2
-
25
-
-
0032015110
-
Effect of recombinant interleukin-1 β on murine CD14 gene expression in vivo
-
Fearns, C. & Ulevitch, R. J. Effect of recombinant interleukin-1 β on murine CD14 gene expression in vivo. Shock 9, 157-163 (1998).
-
(1998)
Shock
, vol.9
, pp. 157-163
-
-
Fearns, C.1
Ulevitch, R.J.2
-
26
-
-
84984752567
-
-
Zekki, H., Feinstein, D. L. & Rivest, S. The clinical course of experimental autoimmune encephalomyelitis is associated with a profound and sustained transcriptional activation of the genes encoding toll-like receptor 2 and CD14 in the mouse CNS. Brain Pathol. (in the press).
-
-
-
Zekki, H.1
Feinstein, D.L.2
Rivest, S.3
-
27
-
-
0034765498
-
Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: No requirement for proapoptotic interleukin-1 β in neurodegeneration
-
Nguyen, M. D., Julien, J.-P & Rivest, S. Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1 β in neurodegeneration. Ann. Neurol. 50, 630-639 (2001).
-
(2001)
Ann. Neurol
, vol.50
, pp. 630-639
-
-
Nguyen, M.D.1
Julien, J.-P.2
Rivest, S.3
-
28
-
-
0031881687
-
Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system
-
Castano, A., Herrera, A. J., Cano, J. & Machado, A. Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system. J. Neurochem. 70, 1584-1592 (1998).
-
(1998)
J. Neurochem.
, vol.70
, pp. 1584-1592
-
-
Castano, A.1
Herrera, A.J.2
Cano, J.3
Machado, A.4
-
29
-
-
0034663061
-
Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: Role of microglia
-
Kim, W. G. et al. Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia. J. Neurosci. 20, 6309-6316 (2000).
-
(2000)
J. Neurosci
, vol.20
, pp. 6309-6316
-
-
Kim, W.G.1
-
30
-
-
0035064940
-
Bacterial endotoxin sensitizes the immature brain to hypoxic-ischaemic injury
-
Eklind, S. et al. Bacterial endotoxin sensitizes the immature brain to hypoxic-ischaemic injury. Eur. J. Neurosci. 13, 1101-1106 (2001).
-
(2001)
Eur. J. Neurosci
, vol.13
, pp. 1101-1106
-
-
Eklind, S.1
-
31
-
-
0034663946
-
Central neivous system-initiated inflammation and neurotropism in trauma: IL-1 β is required for the production of ciliary neurotrophic factor
-
Herx, L. M., Rivest, S. & Yong, V. W. Central neivous system-initiated inflammation and neurotropism in trauma: IL-1 β is required for the production of ciliary neurotrophic factor. J. Immunol. 165, 2232-2239 (2000).
-
(2000)
J. Immunol
, vol.165
, pp. 2232-2239
-
-
Herx, L.M.1
Rivest, S.2
Yong, V.W.3
-
32
-
-
0028326548
-
Secondary cell death and the inflammatory reaction after dorsal hemisection of the rat spinal cord
-
Dusart, I. & Schwab, M. E. Secondary cell death and the inflammatory reaction after dorsal hemisection of the rat spinal cord. Eur. J. Neurosci. 6, 712-724 (1994).
-
(1994)
Eur. J. Neurosci.
, vol.6
, pp. 712-724
-
-
Dusart, I.1
Schwab, M.E.2
-
33
-
-
0030106250
-
Cellular reactions at the lesion site after crushing of the rat optic nee
-
Frank, M. & Wolburg, H. Cellular reactions at the lesion site after crushing of the rat optic nee. Glia 16, 227-240 (1996).
-
(1996)
Glia
, vol.16
, pp. 227-240
-
-
Frank, M.1
Wolburg, H.2
-
34
-
-
0025173499
-
Regional and cellular codistribution of interleukin-1 β and nerve growth factor mRNA in the adult rat brain
-
Bandtlow, C. E. et al. Regional and cellular codistribution of interleukin-1 β and nerve growth factor mRNA in the adult rat brain. J. Cell Biol. 111, 1701-1711 (1990).
-
(1990)
J. Cell Biol
, vol.111
, pp. 1701-1711
-
-
Bandtlow, C.E.1
-
35
-
-
0030032033
-
Interleukin-1 receptor antagonist suppresses neurotrophin response in injured rat brain
-
DeKosky, S. T. et al. Interleukin-1 receptor antagonist suppresses neurotrophin response in injured rat brain. Ann. Neurol. 39, 123-127 (1996).
-
(1996)
Ann. Neurol
, vol.39
, pp. 123-127
-
-
Dekosky, S.T.1
-
36
-
-
0035883161
-
Interleukin-1 β promotes repair of the CNS
-
Mason, J. L., Suzuki, K., Chaplin, D. D. & Matsushima, G. K. Interleukin-1 β promotes repair of the CNS. J. Neurosci. 21, 7046-7052 (2001).
-
(2001)
J. Neurosci
, vol.21
, pp. 7046-7052
-
-
Mason, J.L.1
Suzuki, K.2
Chaplin, D.D.3
Matsushima, G.K.4
-
37
-
-
0033578426
-
A new mechanism of neurodegeneration: A proinflammatory cytokine inhibits receptor signaling by a survival peptide
-
Venters, H. D. et al. A new mechanism of neurodegeneration: a proinflammatory cytokine inhibits receptor signaling by a survival peptide. Proc. Natl Acad. Sci. USA 96, 9879-9884 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 9879-9884
-
-
Venters, H.D.1
-
38
-
-
0035705454
-
TNFα promotes proliferation of oligodendrocyte progenitors and remyelination
-
Arnett, H. A. et al. TNFα promotes proliferation of oligodendrocyte progenitors and remyelination. Nature Neurosci. 4, 1116-1122 (2001).
-
(2001)
Nature Neurosci
, vol.4
, pp. 1116-1122
-
-
Arnett, H.A.1
-
39
-
-
0034656415
-
IFNγ enhances microglial reactions to hippocampal axonal degeneration
-
Jensen, M. B., Hegelund, I. V., Lomholt, N. D., Finsen, B. & Owens, T. IFNγ enhances microglial reactions to hippocampal axonal degeneration. J. Neurosci. 20, 3612-3621 (2000).
-
(2000)
J. Neurosci
, vol.20
, pp. 3612-3621
-
-
Jensen, M.B.1
Hegelund, I.V.2
Lomholt, N.D.3
Finsen, B.4
Owens, T.5
-
40
-
-
0034069944
-
Interferon-γ modulates human oligodendrocyte susceptibility to Fas-mediated apoptosis
-
Pouly, S., Becher, B., Blain, M. & Antel, J. P Interferon-γ modulates human oligodendrocyte susceptibility to Fas-mediated apoptosis. J. Neuropathol. Exp. Neurol. 59, 280-286 (2000).
-
(2000)
J. Neuropathol. Exp. Neurol
, vol.59
, pp. 280-286
-
-
Pouly, S.1
Becher, B.2
Blain, M.3
Antel, J.P.4
-
41
-
-
0032190264
-
Cyclooxygenase and inflammation in Alzheimer's disease: Experimental approaches and clinical interventions
-
Pasinetti, G. M. Cyclooxygenase and inflammation in Alzheimer's disease: experimental approaches and clinical interventions. J. Neurosci. Res. 54, 1-6 (1998).
-
(1998)
J. Neurosci. Res
, vol.54
, pp. 1-6
-
-
Pasinetti, G.M.1
-
42
-
-
0032942060
-
Microglia as mediators of inflammatory and degenerative diseases
-
Gonzalez-Scarano, F. & Baltuch, G. Microglia as mediators of inflammatory and degenerative diseases. Annu. Rev. Neurosci. 22, 219-240 (1999).
-
(1999)
Annu. Rev. Neurosci.
, vol.22
, pp. 219-240
-
-
Gonzalez-Scarano, F.1
Baltuch, G.2
-
43
-
-
0035936804
-
Amyotrophic lateral sclerosis: Unfolding the toxicity of the misfolded
-
Julien, J.-P. Amyotrophic lateral sclerosis: unfolding the toxicity of the misfolded. Cell 104, 581-591 (2001)
-
(2001)
Cell
, vol.104
, pp. 581-591
-
-
Julien, J.-P.1
-
44
-
-
0027160921
-
Tumor necrosis factor-α in immune-mediated demyelination and Wallerian degeneration of the rat peripheral nervous system
-
Stoll, G., Jung, S., Jander, S., van der Meide, P. & Hartung, H. P. Tumor necrosis factor-α in immune-mediated demyelination and Wallerian degeneration of the rat peripheral nervous system. J. Neuroimmunol. 45, 175-182 (1993).
-
(1993)
J. Neuroimmunol.
, vol.45
, pp. 175-182
-
-
Stoll, G.1
Jung, S.2
Jander, S.3
Van Der Meide, P.4
Hartung, H.P.5
-
45
-
-
0034915133
-
Therapeutic neutralization of CD95- ligand and TNF attenuates brain damage in stroke
-
Martin-Villalba, A. et al. Therapeutic neutralization of CD95- ligand and TNF attenuates brain damage in stroke. Cell Death Differ. 8, 679-686 (2001).
-
(2001)
Cell Death Differ
, vol.8
, pp. 679-686
-
-
Martin-Villalba, A.1
-
46
-
-
0035889079
-
Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-α
-
Robertson, J. et al. Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-α. J. Cell Biol. 155, 217-226 (2001).
-
(2001)
J. Cell Biol
, vol.155
, pp. 217-226
-
-
Robertson, J.1
-
48
-
-
0023949553
-
Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo
-
Hickey, W. F. & Kimura, H. Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo. Science 239, 290-292 (1988).
-
(1988)
Science
, vol.239
, pp. 290-292
-
-
Hickey, W.F.1
Kimura, H.2
-
49
-
-
0033396991
-
Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases
-
Mattson, M. P, Pedersen, W. A., Duan, W., Culmsee, C. & Camandola, S. Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases. Ann. NY Acad. Sci. 893, 154-175 (1999).
-
(1999)
Ann. NY Acad. Sci
, vol.893
, pp. 154-175
-
-
Mattson, M.P.1
Pedersen, W.A.2
Duan, W.3
Culmsee, C.4
Camandola, S.5
-
50
-
-
0033624419
-
Mitochondrial dysfunction and oxidative stress in aging and neurodegenerative disease
-
Albers, D. S. & Beal, M. F. Mitochondrial dysfunction and oxidative stress in aging and neurodegenerative disease. J. Neural Transm. 59, 133-154 (2000).
-
(2000)
J. Neural Transm
, vol.59
, pp. 133-154
-
-
Albers, D.S.1
Beal, M.F.2
-
51
-
-
0029079852
-
Induction of MHC class I genes in neurons
-
Neumann, H., Cavalie, A., Jenne, D. E. & Wekerle, H. Induction of MHC class I genes in neurons. Science 269, 549-552 (1995).
-
(1995)
Science
, vol.269
, pp. 549-552
-
-
Neumann, H.1
Cavalie, A.2
Jenne, D.E.3
Wekerle, H.4
-
52
-
-
0031054508
-
Major histocompatibility complex (MHC) class I gene expression in single neurons of the central nervous system: Differential regulation by interferon (IFN)-γ and tumor necrosis factor (TNF)-α
-
Neumann, H., Schmidt, H., Cavalie, A., Jenne, D. & Wekerle, H. Major histocompatibility complex (MHC) class I gene expression in single neurons of the central nervous system: differential regulation by interferon (IFN)-γ and tumor necrosis factor (TNF)-α. J. Exp. Med. 185, 305-316 (1997).
-
(1997)
J. Exp. Med
, vol.185
, pp. 305-316
-
-
Neumann, H.1
Schmidt, H.2
Cavalie, A.3
Jenne, D.4
Wekerle, H.5
-
53
-
-
0032168898
-
Regulation of class I MHC gene expression in the developing and mature CNS by neural activity
-
Corriveau, R. A., Huh, G. S. & Shatz, C. J. Regulation of class I MHC gene expression in the developing and mature CNS by neural activity. Neuron 21, 505-520 (1998).
-
(1998)
Neuron
, vol.21
, pp. 505-520
-
-
Corriveau, R.A.1
Huh, G.S.2
Shatz, C.J.3
-
54
-
-
0032215712
-
Immunologic complexity in neurons
-
Darnell, R. B. Immunologic complexity in neurons. Neuron 21, 947-950 (1998).
-
(1998)
Neuron
, vol.21
, pp. 947-950
-
-
Darnell, R.B.1
-
55
-
-
0034922092
-
Paraneoplastic neurologic disease antigens: RNA-binding proteins and signaling proteins in neuronal degeneration
-
Musunuru, K. & Darnell, R. B. Paraneoplastic neurologic disease antigens: RNA-binding proteins and signaling proteins in neuronal degeneration. Annu. Rev. Neurosci. 24, 239-262 (2001).
-
(2001)
Annu. Rev. Neurosci
, vol.24
, pp. 239-262
-
-
Musunuru, K.1
Darnell, R.B.2
-
56
-
-
0033635740
-
P Synaptic autoimmunity and the Salk factor
-
Solimena, M. & De Camilli, P Synaptic autoimmunity and the Salk factor. Neuron 28, 309-310 (2000).
-
(2000)
Neuron
, vol.28
, pp. 309-310
-
-
Solimena, M.1
De, C.2
-
57
-
-
0032964881
-
Autoimmunity and neurological disease: Antibody modulation of synaptic transmission
-
Whitney, K. D. & McNamara, J. O. Autoimmunity and neurological disease: antibody modulation of synaptic transmission. Annu. Rev. Neurosci. 22, 175-195 (1999).
-
(1999)
Annu. Rev. Neurosci
, vol.22
, pp. 175-195
-
-
Whitney, K.D.1
McNamara, J.O.2
-
58
-
-
0031868110
-
Experimental destruction of substantia nigra initiated by Parkinson disease immunoglobulins
-
Chen, S. et al. Experimental destruction of substantia nigra initiated by Parkinson disease immunoglobulins. Arch. Neurol. 55, 1075-1080 (1998).
-
(1998)
Arch. Neurol
, vol.55
, pp. 1075-1080
-
-
Chen, S.1
-
59
-
-
0031886287
-
Glutamate receptor GluR3 antibodies and death of cortical cells
-
He, X. P. et al. Glutamate receptor GluR3 antibodies and death of cortical cells. Neuron 20, 153-163 (1998).
-
(1998)
Neuron
, vol.20
, pp. 153-163
-
-
He, X.P.1
-
60
-
-
0029007095
-
Antibodies to calcium channels from ALS patients passively transferred to mice selectively increase intracellular calcium and induce ultrastructural changes in motoneurons
-
Engelhardt, J. I., Siklos, L., Komuves, L., Smith, R. G. & Appel, S. H. Antibodies to calcium channels from ALS patients passively transferred to mice selectively increase intracellular calcium and induce ultrastructural changes in motoneurons. Synapse 20, 185-199 (1995).
-
(1995)
Synapse
, vol.20
, pp. 185-199
-
-
Engelhardt, J.I.1
Siklos, L.2
Komuves, L.3
Smith, R.G.4
Appel, S.H.5
-
61
-
-
0034065273
-
Stereotaxic injection of IgG from patients with Alzheimer disease initiates injury of cholinergic neurons of the basal forebrain
-
Engelhardt, J. I. et al. Stereotaxic injection of IgG from patients with Alzheimer disease initiates injury of cholinergic neurons of the basal forebrain. Arch. Neurol. 57, 681-686 (2000).
-
(2000)
Arch. Neurol.
, vol.57
, pp. 681-686
-
-
Engelhardt, J.I.1
-
62
-
-
0030992812
-
The neuronal RNA binding protein Nova-1 recognizes specific RNA targets in vitro and in vivo
-
Buckanovich, R. J. & Darnell, R. B. The neuronal RNA binding protein Nova-1 recognizes specific RNA targets in vitro and in vivo. Mol. Cell. Biol. 17, 3194-3201 (1997).
-
(1997)
Mol. Cell. Biol
, vol.17
, pp. 3194-3201
-
-
Buckanovich, R.J.1
Darnell, R.B.2
-
63
-
-
0029875911
-
The onconeural antigen Nova-1 is a neuron-specific RNA-binding protein, the activity of which is inhibited by paraneoplastic antibodies
-
Buckanovich, R. J., Yang, Y. Y & Darnell, R. B. The onconeural antigen Nova-1 is a neuron-specific RNA-binding protein, the activity of which is inhibited by paraneoplastic antibodies. J. Neurosci. 16, 1114-1122 (1996).
-
(1996)
J. Neurosci
, vol.16
, pp. 1114-1122
-
-
Buckanovich, R.J.1
Yang, Y.Y.2
Darnell, R.B.3
-
64
-
-
0027374048
-
Nova, the paraneoplastic Ri antigen, is homologous to an RNA- binding protein and is specifically expressed in the developing motor system
-
Buckanovich, R. J., Posner, J. B. & Darnell, R. B. Nova, the paraneoplastic Ri antigen, is homologous to an RNA- binding protein and is specifically expressed in the developing motor system. Neuron 11, 657-672 (1993).
-
(1993)
Neuron
, vol.11
, pp. 657-672
-
-
Buckanovich, R.J.1
Posner, J.B.2
Darnell, R.B.3
-
65
-
-
0033757702
-
Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability
-
Jensen, K. B. et al. Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability. Neuron 25, 359-371 (2000).
-
(2000)
Neuron
, vol.25
, pp. 359-371
-
-
Jensen, K.B.1
-
66
-
-
0028153174
-
Apoptotic cell death of a hybrid motoneuron cell line induced by immunoglobulins from patients with amyotrophic lateral sclerosis
-
Alexianu, M. E., Mohamed, A. H., Smith, R. G., Colom, L. V. & Appel, S. H. Apoptotic cell death of a hybrid motoneuron cell line induced by immunoglobulins from patients with amyotrophic lateral sclerosis. J. Neurochem. 63, 2365-2368 (1994).
-
(1994)
J. Neurochem
, vol.63
, pp. 2365-2368
-
-
Alexianu, M.E.1
Mohamed, A.H.2
Smith, R.G.3
Colom, L.V.4
Appel, S.H.5
-
67
-
-
0030638138
-
Altered calcium homeostasis and ultrastructure in motoneurons of mice caused by passively transferred anti-motoneuronal IgG
-
Engelhardt, J. I., Siklos, L. & Appel, S. H. Altered calcium homeostasis and ultrastructure in motoneurons of mice caused by passively transferred anti-motoneuronal IgG. J. Neuropathol. Exp. Neurol. 56, 21-39 (1997).
-
(1997)
J. Neuropathol. Exp. Neurol.
, vol.56
, pp. 21-39
-
-
Engelhardt, J.I.1
Siklos, L.2
Appel, S.H.3
-
68
-
-
0034327381
-
Ultrastructural analysis of spinal motoneurones from mice treated with IgG from ALS patients, healthy individuals, or disease controls
-
Pullen, A. H. & Humphreys, P. Ultrastructural analysis of spinal motoneurones from mice treated with IgG from ALS patients, healthy individuals, or disease controls. J. Neurol. Sci. 180, 35-45 (2000).
-
(2000)
J. Neurol. Sci
, vol.180
, pp. 35-45
-
-
Pullen, A.H.1
Humphreys, P.2
-
69
-
-
0035828147
-
Recruitment of activated microglia cells in the spinal cord of mice by ALS IgG
-
Obal, I., Jakab, J. S., Siklos, L. & Engelhardt, J. I. Recruitment of activated microglia cells in the spinal cord of mice by ALS IgG. Neuroreport 12, 2449-2452 (2001).
-
(2001)
Neuroreport
, vol.12
, pp. 2449-2452
-
-
Obal, I.1
Jakab, J.S.2
Siklos, L.3
Engelhardt, J.I.4
-
70
-
-
0028095257
-
Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis
-
Rogers, S. W. et al. Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis. Science 265, 648-651 (1994).
-
(1994)
Science
, vol.265
, pp. 648-651
-
-
Rogers, S.W.1
-
71
-
-
0033638708
-
Autoimmunity to munc-18 in Rasmussen's encephalitis
-
Yang, R. et al. Autoimmunity to munc-18 in Rasmussen's encephalitis. Neuron 28, 375-383 (2000).
-
(2000)
Neuron
, vol.28
, pp. 375-383
-
-
Yang, R.1
-
72
-
-
0027517423
-
The synaptic vesicle-associated protein amphiphysin is the 128-kD autoantigen of Stiff-Man syndrome with breast cancer
-
De Camilli, P. et al. The synaptic vesicle-associated protein amphiphysin is the 128-kD autoantigen of Stiff-Man syndrome with breast cancer. J. Exp. Med. 178, 2219-2223 (1993).
-
(1993)
J. Exp. Med
, vol.178
, pp. 2219-2223
-
-
De Camilli, P.1
-
73
-
-
0028267951
-
Identification of autoantibody epitopes of glutamic acid decarboxylase in stiff-man syndrome patients
-
Li, L., Hagopian, W. A., Brashear, H. R., Daniels, T. & Lernmark, A. Identification of autoantibody epitopes of glutamic acid decarboxylase in stiff-man syndrome patients. J. Immunol. 152, 930-934 (1994).
-
(1994)
J. Immunol
, vol.152
, pp. 930-934
-
-
Li, L.1
Hagopian, W.A.2
Brashear, H.R.3
Daniels, T.4
Lernmark, A.5
-
74
-
-
0033681271
-
Autoimmunity to gephyrin in Stiff-Man syndrome
-
Butler, M. H. et al. Autoimmunity to gephyrin in Stiff-Man syndrome. Neuron 26, 307-312 (2000).
-
(2000)
Neuron
, vol.26
, pp. 307-312
-
-
Butler, M.H.1
-
75
-
-
0031066631
-
Local-clonal expansion of infiltrating T lymphocytes in chronic encephalitis of Rasmussen
-
Li, Y. et al. Local-clonal expansion of infiltrating T lymphocytes in chronic encephalitis of Rasmussen. J. Immunol. 158, 1428-1437 (1997).
-
(1997)
J. Immunol
, vol.158
, pp. 1428-1437
-
-
Li, Y.1
-
76
-
-
0031786356
-
Tumor-specific killer cells in paraneoplastic cerebellar degeneration
-
Albert, M. L. et al. Tumor-specific killer cells in paraneoplastic cerebellar degeneration. Nature Med. 4, 1321-1324 (1998).
-
(1998)
Nature Med
, vol.4
, pp. 1321-1324
-
-
Albert, M.L.1
-
77
-
-
0033546888
-
Immunoglobulin G and complement immunoreactivity in the cerebral cortex of patients with Rasmussen's encephalitis
-
Whitney, K. D., Andrews, P. I. & McNamara, J. O. Immunoglobulin G and complement immunoreactivity in the cerebral cortex of patients with Rasmussen's encephalitis. Neurology 53, 699-708 (1999).
-
(1999)
Neurology
, vol.53
, pp. 699-708
-
-
Whitney, K.D.1
Rews, P.I.2
McNamara, J.O.3
-
78
-
-
0033962379
-
Detection and treatment of activated T cells in the cerebrospinal fluid of patients with paraneoplastic cerebellar degeneration
-
Albert, M. L., Austin, L. M. & Darnell, R. B. Detection and treatment of activated T cells in the cerebrospinal fluid of patients with paraneoplastic cerebellar degeneration. Ann. Neurol. 47, 9-17 (2000).
-
(2000)
Ann. Neurol
, vol.47
, pp. 9-17
-
-
Albert, M.L.1
Austin, L.M.2
Darnell, R.B.3
-
79
-
-
0024231045
-
Immunity assessment in the early stages of amyotrophic lateral sclerosis: A study of virus antibodies and lymphocyte subsets
-
Provinciali, L. et al. Immunity assessment in the early stages of amyotrophic lateral sclerosis: a study of virus antibodies and lymphocyte subsets. Acta Neurol. Scand. 78, 449-454 (1988)
-
(1988)
Acta Neurol. Scand.
, vol.78
, pp. 449-454
-
-
Provinciali, L.1
-
80
-
-
0024997449
-
Major histocompatibility complex antigen expression in the affected tissues in amyotrophic lateral sclerosis
-
Lampson, L. A., Kushner, P D. & Sobel, R. A. Major histocompatibility complex antigen expression in the affected tissues in amyotrophic lateral sclerosis. Ann. Neurol. 28, 365-372 (1990).
-
(1990)
Ann. Neurol
, vol.28
, pp. 365-372
-
-
Lampson, L.A.1
Kushner, P.D.2
Sobel, R.A.3
-
81
-
-
0025185079
-
Immunohistochemical characterization of the inflammatory infiltrate in amyotrophic lateral sclerosis. Neuropathol
-
Troost, D., van den Oord, J. J. & Vianney de Jong, J. M. Immunohistochemical characterization of the inflammatory infiltrate in amyotrophic lateral sclerosis. Neuropathol. Appl. Neurobiol. 16, 401-410 (1990).
-
(1990)
Appl. Neurobiol
, vol.16
, pp. 401-410
-
-
Troost, D.1
Van Den Oord, J.J.2
Vianney De Jong, J.M.3
-
82
-
-
0032700036
-
T cell receptor BV gene rearrangements in the spinal cords and cerebrospinal fluid of patients with amyotrophic lateral sclerosis
-
Panzara, M. A. et al. T cell receptor BV gene rearrangements in the spinal cords and cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Neurobiol. Dis. 6, 392-405 (1999).
-
(1999)
Neurobiol. Dis
, vol.6
, pp. 392-405
-
-
Panzara, M.A.1
-
83
-
-
0035576934
-
Molecular physiology and pathophysiology of tightjunctions in the blood-brain barrier
-
Huber, J. D., Egleton, R. D. & Davis, T. P. Molecular physiology and pathophysiology of tightjunctions in the blood-brain barrier. Trends Neurosci. 24, 719-725 (2001).
-
(2001)
Trends Neurosci
, vol.24
, pp. 719-725
-
-
Huber, J.D.1
Egleton, R.D.2
Davis, T.P.3
-
84
-
-
0033528254
-
Intravascular infusions of soluble β-amyloid compromise the blood-brain barrier, activate CNS glial cells and induce peripheral hemorrhage
-
Su, G. C., Arendash, G. W., Kalaria, R. N., Bjugstad, K. B. & Mullan, M. Intravascular infusions of soluble β-amyloid compromise the blood-brain barrier, activate CNS glial cells and induce peripheral hemorrhage. Brain Res. 818, 105-117 (1999).
-
(1999)
Brain Res
, vol.818
, pp. 105-117
-
-
Su, G.C.1
Arendash, G.W.2
Kalaria, R.N.3
Bjugstad, K.B.4
Mullan, M.5
-
85
-
-
0031779653
-
Increased blood-brain barrier permeability and endothelial abnormalities induced by vascular endothelial growth factor
-
Dobrogowska, D. H., Lossinsky, A. S., Tarnawski, M. & Vorbrodt, A. W. Increased blood-brain barrier permeability and endothelial abnormalities induced by vascular endothelial growth factor. J. Neurocytol. 27, 163-173 (1998).
-
(1998)
J. Neurocytol.
, vol.27
, pp. 163-173
-
-
Dobrogowska, D.H.1
Lossinsky, A.S.2
Tarnawski, M.3
Vorbrodt, A.W.4
-
86
-
-
0033797255
-
VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain
-
Zhang, Z. G. et al. VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain. J. Clin. Invest. 106, 829-838 (2000).
-
(2000)
J. Clin. Invest
, vol.106
, pp. 829-838
-
-
Zhang, Z.G.1
-
87
-
-
0032991449
-
Vascular endothelial growth factor (VEGF) modulates vascular permeability and inflammation in rat brain
-
Proescholdt, M. A. et al. Vascular endothelial growth factor (VEGF) modulates vascular permeability and inflammation in rat brain. J. Neuropathol. Exp. Neurol. 58, 613-627 (1999).
-
(1999)
J. Neuropathol. Exp. Neurol
, vol.58
, pp. 613-627
-
-
Proescholdt, M.A.1
-
88
-
-
0034978562
-
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
-
Oosthuyse, B. et al. Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration. Nature Genet. 28, 131-138 (2001).
-
(2001)
Nature Genet
, vol.28
, pp. 131-138
-
-
Oosthuyse, B.1
-
89
-
-
0035949791
-
An ALS-like syndrome with new HIV infection and complete response to antiretroviral therapy
-
MacGowan, D. J., Scelsa, S. N. & Waldron, M. An ALS-like syndrome with new HIV infection and complete response to antiretroviral therapy. Neurology 57, 1094-1097 (2001).
-
(2001)
Neurology
, vol.57
, pp. 1094-1097
-
-
Macgowan, D.J.1
Scelsa, S.N.2
Waldron, M.3
-
90
-
-
0035949742
-
Reversible ALS-like disorder in HIV infection
-
Moulignier, A., Moulonguet, A., Pialoux, G. & Rozenbaum, W. Reversible ALS-like disorder in HIV infection. Neurology 57, 995-1001 (2001).
-
(2001)
Neurology
, vol.57
, pp. 995-1001
-
-
Moulignier, A.1
Moulonguet, A.2
Pialoux, G.3
Rozenbaum, W.4
-
91
-
-
0026706840
-
Motor neuron diseases and viruses: Poliovirus, retroviruses, and lymphomas
-
Jubelt, B. Motor neuron diseases and viruses: poliovirus, retroviruses, and lymphomas. Curr. Opin. Neurol. Neurosurg. 5, 655-658 (1992).
-
(1992)
Curr. Opin. Neurol. Neurosurg
, vol.5
, pp. 655-658
-
-
Jubelt, B.1
-
92
-
-
0024439527
-
Enteroviral-related antigen in circulating immune complexes of amyotrophic lateral sclerosis patients
-
Bartfeld, H. et al. Enteroviral-related antigen in circulating immune complexes of amyotrophic lateral sclerosis patients. Intervirology 30, 202-212 (1989).
-
(1989)
Intervirology
, vol.30
, pp. 202-212
-
-
Bartfeld, H.1
-
93
-
-
0027280621
-
Amyotrophic lateral sclerosis an enigmatic disease with B-cellular and anti-retroviral immune responses
-
Westarp, M. E. et al. Amyotrophic lateral sclerosis an enigmatic disease with B-cellular and anti-retroviral immune responses. Eur. J. Med. 2, 327-332 (1993).
-
(1993)
Eur. J. Med
, vol.2
, pp. 327-332
-
-
Westarp, M.E.1
-
94
-
-
0029043835
-
HTLV tax-rex DNA and antibodies in idiopathic amyotrophic lateral sclerosis
-
Ferrante, P. et al. HTLV tax-rex DNA and antibodies in idiopathic amyotrophic lateral sclerosis. J. Neurol. Sci. 129, 140-144 (1995).
-
(1995)
J. Neurol. Sci
, vol.129
, pp. 140-144
-
-
Ferrante, P.1
-
95
-
-
0033981056
-
Detection and cellular localization of enterovirus RNA sequences in spinal cord of patients with ALS
-
Berger, M. M. et al. Detection and cellular localization of enterovirus RNA sequences in spinal cord of patients with ALS. Neurology 54, 20-25 (2000).
-
(2000)
Neurology
, vol.54
, pp. 20-25
-
-
Berger, M.M.1
-
96
-
-
0030442033
-
AIDS dementia complex: A complex, slow virus 'model' of acquired genetic neurodegenerative disease
-
Price, R. W. AIDS dementia complex: a complex, slow virus 'model' of acquired genetic neurodegenerative disease. Cold Spring Harb. Symp. Quant. Biol. 61, 759-770 (1996).
-
(1996)
Cold Spring Harb. Symp. Quant. Biol
, vol.61
, pp. 759-770
-
-
Price, R.W.1
-
98
-
-
0031929574
-
Degeneration of the cerebellar granule cell layer in transgenic mice expressing genes of human foamy virus
-
Lampe, J., Marino, S., Rethwilm, A. & Aguzzi, A. Degeneration of the cerebellar granule cell layer in transgenic mice expressing genes of human foamy virus. Neuropathol. Appl. Neurobiol. 24, 36-43 (1998).
-
(1998)
Neuropathol. Appl. Neurobiol
, vol.24
, pp. 36-43
-
-
Lampe, J.1
Marino, S.2
Rethwilm, A.3
Aguzzi, A.4
-
99
-
-
0034704377
-
Spatial memory and learning deficits after experimental pneumococcal meningitis in mice
-
Wellmer, A., Noeske, C., Gerber, J., Munzel, U. & Nau, R. Spatial memory and learning deficits after experimental pneumococcal meningitis in mice. Neurosci. Lett. 296, 137-140 (2000).
-
(2000)
Neurosci. Lett.
, vol.296
, pp. 137-140
-
-
Wellmer, A.1
Noeske, C.2
Gerber, J.3
Munzel, U.4
Nau, R.5
-
100
-
-
0035103936
-
LP-BM5 virus-infected mice produce activating autoantibodies to the AMPA receptor
-
Koustova, E. et al. LP-BM5 virus-infected mice produce activating autoantibodies to the AMPA receptor. J. Clin. Invest. 107, 737-744 (2001).
-
(2001)
J. Clin. Invest
, vol.107
, pp. 737-744
-
-
Koustova, E.1
-
101
-
-
0034927789
-
Age-dependent poliomyelitis in mice is associated with respiratory failure and viral replication in the central nervous system and lung
-
Schlenker, E. H., Jones, Q. A., Rowland, R. R., Steffen-Bien, M. & Cafruny, W. A. Age-dependent poliomyelitis in mice is associated with respiratory failure and viral replication in the central nervous system and lung. J. Neurovirol. 7, 265-271 (2001).
-
(2001)
J. Neurovirol
, vol.7
, pp. 265-271
-
-
Schlenker, E.H.1
Jones, Q.A.2
Rowland, R.R.3
Steffen-Bien, M.4
Cafruny, W.A.5
|