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Volumn 24, Issue 15, 2004, Pages 3752-3761

Passive or Active Immunization with Myelin Basic Protein Impairs Neurological Function and Exacerbates Neuropathology after Spinal Cord Injury in Rats

Author keywords

Autoimmunity; EAE; Inflammation; Myelin basic protein; Neuroprotection; Vaccine

Indexed keywords

MYELIN BASIC PROTEIN;

EID: 1942521774     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0406-04.2004     Document Type: Article
Times cited : (119)

References (74)
  • 1
    • 0037967530 scopus 로고    scopus 로고
    • Interleukin-12 induces mild experimental allergic encephalomyelitis following local central nervous system injury in the Lewis rat
    • Ahmed Z, Baker D, Cuzner ML (2003) Interleukin-12 induces mild experimental allergic encephalomyelitis following local central nervous system injury in the Lewis rat. J Neuroimmunol 140:109-117.
    • (2003) J Neuroimmunol , vol.140 , pp. 109-117
    • Ahmed, Z.1    Baker, D.2    Cuzner, M.L.3
  • 2
    • 0031659763 scopus 로고    scopus 로고
    • Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice
    • Akassoglou K, Bauer J, Kassiotis G, Pasparakis M, Lassman H, Kollias G, Probert L (1998) Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice. Am J Pathol 153:801-813.
    • (1998) Am J Pathol , vol.153 , pp. 801-813
    • Akassoglou, K.1    Bauer, J.2    Kassiotis, G.3    Pasparakis, M.4    Lassman, H.5    Kollias, G.6    Probert, L.7
  • 5
    • 0028270477 scopus 로고
    • Oligodendrocyte lysis by CD4+ T cells independent of tumor necrosis factor
    • Antel JP, Williams K, Blain M, McRea E, McLaurin J (1994) Oligodendrocyte lysis by CD4+ T cells independent of tumor necrosis factor. Ann Neurol 35:341-348.
    • (1994) Ann Neurol , vol.35 , pp. 341-348
    • Antel, J.P.1    Williams, K.2    Blain, M.3    McRea, E.4    McLaurin, J.5
  • 6
    • 0031027581 scopus 로고    scopus 로고
    • Increased interleukin 12 production in progressive multiple sclerosis: Induction by activated CD4+ T cells via CD40 ligand
    • Balashov KE, Smith DR, Khoury SJ, Hafler DA, Weiner HL (1997) Increased interleukin 12 production in progressive multiple sclerosis: induction by activated CD4+ T cells via CD40 ligand. Proc Natl Acad Sci USA 94:599-603.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 599-603
    • Balashov, K.E.1    Smith, D.R.2    Khoury, S.J.3    Hafler, D.A.4    Weiner, H.L.5
  • 7
    • 0028919411 scopus 로고
    • A sensitive and reliable locomotor rating scale for open field testing in rats
    • Basso DM, Beattie MS, Bresnahan JC (1995) A sensitive and reliable locomotor rating scale for open field testing in rats. J Neurotrauma 12:1-21.
    • (1995) J Neurotrauma , vol.12 , pp. 1-21
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 8
    • 0030157694 scopus 로고    scopus 로고
    • Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection
    • Basso DM, Beattie MS, Bresnahan JC (1996) Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection. Exp Neurol 139:244-256.
    • (1996) Exp Neurol , vol.139 , pp. 244-256
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 9
    • 0036957199 scopus 로고    scopus 로고
    • Descending systems contributing to locomotor recovery after mild or moderate spinal cord injury in rats: Experimental evidence and a review of literature
    • Basso DM, Beattie MS, Bresnahan JC (2002) Descending systems contributing to locomotor recovery after mild or moderate spinal cord injury in rats: experimental evidence and a review of literature. Restor Neurol Neurosci 20:189-218.
    • (2002) Restor Neurol Neurosci , vol.20 , pp. 189-218
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 10
    • 0033747044 scopus 로고    scopus 로고
    • Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway
    • Basu S, Binder RJ, Suto R, Anderson KM, Srivastava PK (2000) Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway. Int Immunol 12:1539-1546.
    • (2000) Int Immunol , vol.12 , pp. 1539-1546
    • Basu, S.1    Binder, R.J.2    Suto, R.3    Anderson, K.M.4    Srivastava, P.K.5
  • 11
    • 0033104019 scopus 로고    scopus 로고
    • Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor
    • Batchelor PE, Liberatore GT, Wong JYF, Porritt MJ, Frerichs F, Donnan GA, Howells DW (1999) Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor. J Neurosci 19:1708-1716.
    • (1999) J Neurosci , vol.19 , pp. 1708-1716
    • Batchelor, P.E.1    Liberatore, G.T.2    Wong, J.Y.F.3    Porritt, M.J.4    Frerichs, F.5    Donnan, G.A.6    Howells, D.W.7
  • 13
    • 0026472710 scopus 로고
    • Spinal cord injury produced by consistent displacement of the cord in rats: Behavioral and histologic analysis
    • Behrmann DL, Bresnahan JC, Beattie MS, Shah BR (1992) Spinal cord injury produced by consistent displacement of the cord in rats: behavioral and histologic analysis. J Neurotrauma 9:197-217.
    • (1992) J Neurotrauma , vol.9 , pp. 197-217
    • Behrmann, D.L.1    Bresnahan, J.C.2    Beattie, M.S.3    Shah, B.R.4
  • 14
    • 0038077547 scopus 로고    scopus 로고
    • Efficient central nervous system remyelination requires T cells
    • Bieber AJ, Kerr S, Rodriguez M (2003) Efficient central nervous system remyelination requires T cells. Ann Neurol 53:680-684.
    • (2003) Ann Neurol , vol.53 , pp. 680-684
    • Bieber, A.J.1    Kerr, S.2    Rodriguez, M.3
  • 16
    • 0032191586 scopus 로고    scopus 로고
    • Heat shock proteins and experimental autoimmune encephalomyelitis. II: Environmental infection and extra-neuraxial inflammation alter the course of chronic relapsing encephalomyelitis
    • Birnbaum G, Kotilinek L, Miller SD, Raine CS, Gao YL, Lehmann PV, Gupta RS (1998) Heat shock proteins and experimental autoimmune encephalomyelitis. II: environmental infection and extra-neuraxial inflammation alter the course of chronic relapsing encephalomyelitis. J Neuroimmunol 90:149-161.
    • (1998) J Neuroimmunol , vol.90 , pp. 149-161
    • Birnbaum, G.1    Kotilinek, L.2    Miller, S.D.3    Raine, C.S.4    Gao, Y.L.5    Lehmann, P.V.6    Gupta, R.S.7
  • 17
    • 0034652558 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha mRNA expression in early multiple sclerosis lesions: Correlation with demyelinating activity and oligodendrocyte pathology
    • Bitsch A, Kuhlmann T, Da Costa C, Bunkowski S, Polak T, Bruck W (2000) Tumour necrosis factor alpha mRNA expression in early multiple sclerosis lesions: correlation with demyelinating activity and oligodendrocyte pathology. Glia 29:366-375.
    • (2000) Glia , vol.29 , pp. 366-375
    • Bitsch, A.1    Kuhlmann, T.2    Da Costa, C.3    Bunkowski, S.4    Polak, T.5    Bruck, W.6
  • 18
    • 0032866662 scopus 로고    scopus 로고
    • Sympathetic ophthalmia: An autoimmune ocular inflammatory disease
    • Chan CC, Mochizuki M (1999) Sympathetic ophthalmia: an autoimmune ocular inflammatory disease. Springer Semin Immunopathol 21:125-134.
    • (1999) Springer Semin Immunopathol , vol.21 , pp. 125-134
    • Chan, C.C.1    Mochizuki, M.2
  • 19
    • 0033560023 scopus 로고    scopus 로고
    • Regulation of interleukin (IL)-12 receptor beta2 subunit expression by endogenous IL-12: A critical step in the differentiation of pathogenic autoreactive T cells
    • Chang JT, Shevach EM, Segal BM (1999) Regulation of interleukin (IL)-12 receptor beta2 subunit expression by endogenous IL-12: a critical step in the differentiation of pathogenic autoreactive T cells. J Exp Med 189:969-978.
    • (1999) J Exp Med , vol.189 , pp. 969-978
    • Chang, J.T.1    Shevach, E.M.2    Segal, B.M.3
  • 20
    • 0037203825 scopus 로고    scopus 로고
    • Nerve inflammation halts trial for Alzheimer's drug
    • Check E (2002) Nerve inflammation halts trial for Alzheimer's drug. Nature 415:462.
    • (2002) Nature , vol.415 , pp. 462
    • Check, E.1
  • 21
    • 0346101750 scopus 로고    scopus 로고
    • Reduced susceptibility to kainic acid-induced excitoxicity in T-cell deficient CD4/ CD8(-/-) and middle-aged C57BL/6 mice
    • Chen Z, Ljunggren HG, Zhu SW, Winblad B, Zhu J (2004) Reduced susceptibility to kainic acid-induced excitoxicity in T-cell deficient CD4/ CD8(-/-) and middle-aged C57BL/6 mice. J Neuroimmunol 146:33-38.
    • (2004) J Neuroimmunol , vol.146 , pp. 33-38
    • Chen, Z.1    Ljunggren, H.G.2    Zhu, S.W.3    Winblad, B.4    Zhu, J.5
  • 22
    • 0032994147 scopus 로고    scopus 로고
    • The immunobiology of multiple sclerosis: An autoimmune disease of the central nervous system
    • Conlon P, Oksenberg JR, Zhang J, Steinman L (1999) The immunobiology of multiple sclerosis: an autoimmune disease of the central nervous system. Neurobiol Dis 6:149-166.
    • (1999) Neurobiol Dis , vol.6 , pp. 149-166
    • Conlon, P.1    Oksenberg, J.R.2    Zhang, J.3    Steinman, L.4
  • 24
    • 0029012783 scopus 로고
    • The relationships among the severity of spinal cord injury, residual neurological function, axon counts, and counts of retrogradely labeled neurons after experimental spinal cord injury
    • Fehlings MG, Tator CH (1995) The relationships among the severity of spinal cord injury, residual neurological function, axon counts, and counts of retrogradely labeled neurons after experimental spinal cord injury. Exp Neurol 132:220-228.
    • (1995) Exp Neurol , vol.132 , pp. 220-228
    • Fehlings, M.G.1    Tator, C.H.2
  • 26
    • 0033917384 scopus 로고    scopus 로고
    • Axonal damage induced by invading T cells in organotypic central nervous system tissue in vitro: Involvement of microglial cells
    • Gimsa U, Peter SV, Lehmann K, Bechmann I, Nitsch R (2000) Axonal damage induced by invading T cells in organotypic central nervous system tissue in vitro: involvement of microglial cells. Brain Pathol 10:365-377.
    • (2000) Brain Pathol , vol.10 , pp. 365-377
    • Gimsa, U.1    Peter, S.V.2    Lehmann, K.3    Bechmann, I.4    Nitsch, R.5
  • 27
    • 0037530542 scopus 로고    scopus 로고
    • Vulnerability of human neurons to T cell-mediated cytotoxicity
    • Giuliani F, Goodyer CG, Antel JP, Yong VW (2003) Vulnerability of human neurons to T cell-mediated cytotoxicity. J Immunol 171:368-379.
    • (2003) J Immunol , vol.171 , pp. 368-379
    • Giuliani, F.1    Goodyer, C.G.2    Antel, J.P.3    Yong, V.W.4
  • 28
    • 0345688977 scopus 로고    scopus 로고
    • Reducing inflammation decreases secondary degeneration and functional deficit after spinal cord injury
    • Gonzalez R, Glaser J, Liu MT, Lane TE, Keirstead HS (2003) Reducing inflammation decreases secondary degeneration and functional deficit after spinal cord injury. Exp Neurol 184:456-463.
    • (2003) Exp Neurol , vol.184 , pp. 456-463
    • Gonzalez, R.1    Glaser, J.2    Liu, M.T.3    Lane, T.E.4    Keirstead, H.S.5
  • 33
    • 0034893791 scopus 로고    scopus 로고
    • Posttraumatic therapeutic vaccination with modified myelin self-antigen prevents complete paralysis while avoiding autoimmune disease
    • Hauben E, Agranov E, Gothilf A, Nevo U, Cohen A, Smirnov I, Steinman L, Schwartz M (2001a) Posttraumatic therapeutic vaccination with modified myelin self-antigen prevents complete paralysis while avoiding autoimmune disease. J Clin Invest 108:591-599.
    • (2001) J Clin Invest , vol.108 , pp. 591-599
    • Hauben, E.1    Agranov, E.2    Gothilf, A.3    Nevo, U.4    Cohen, A.5    Smirnov, I.6    Steinman, L.7    Schwartz, M.8
  • 34
    • 0035910038 scopus 로고    scopus 로고
    • Vaccination with a Nogo-A-derived peptide after incomplete spinal-cord injury promotes recovery via a T-cell-mediated neuroprotective response: Comparison with other myelin antigens
    • Hauben E, Ibarra A, Mizrahi T, Barouch R, Agranov E, Schwartz M (2001b) Vaccination with a Nogo-A-derived peptide after incomplete spinal-cord injury promotes recovery via a T-cell-mediated neuroprotective response: comparison with other myelin antigens. Proc Natl Acad Sci USA 98:15173-15178.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 15173-15178
    • Hauben, E.1    Ibarra, A.2    Mizrahi, T.3    Barouch, R.4    Agranov, E.5    Schwartz, M.6
  • 35
    • 0036311119 scopus 로고    scopus 로고
    • Elevated serum titers of proinflammatory cytokines and CNS autoantibodies in patients with chronic spinal cord injury
    • Hayes KC, Hull TC, Delaney GA, Potter PJ, Sequeira KA, Campbell K, Popovich PG (2002) Elevated serum titers of proinflammatory cytokines and CNS autoantibodies in patients with chronic spinal cord injury. J Neurotrauma 19:753-761.
    • (2002) J Neurotrauma , vol.19 , pp. 753-761
    • Hayes, K.C.1    Hull, T.C.2    Delaney, G.A.3    Potter, P.J.4    Sequeira, K.A.5    Campbell, K.6    Popovich, P.G.7
  • 36
    • 0027199238 scopus 로고
    • Perforin and tumor necrosis factor alpha in the pathogenesis of experimental allergic encephalomyelitis: Comparison of autoantigen induced and transferred disease in Lewis rats
    • Held W, Meyermann R, Qin Y, Mueller C (1993) Perforin and tumor necrosis factor alpha in the pathogenesis of experimental allergic encephalomyelitis: comparison of autoantigen induced and transferred disease in Lewis rats. J Autoimmun 6:311-322.
    • (1993) J Autoimmun , vol.6 , pp. 311-322
    • Held, W.1    Meyermann, R.2    Qin, Y.3    Mueller, C.4
  • 37
    • 0023265037 scopus 로고
    • A quantitative immunohistochemical comparison of actively versus adoptively induced experimental allergic encephalomyelitis in the Lewis rat
    • Hickey WF, Cohen JA, Burns JB (1987) A quantitative immunohistochemical comparison of actively versus adoptively induced experimental allergic encephalomyelitis in the Lewis rat. Cell Immunol 109:272-281.
    • (1987) Cell Immunol , vol.109 , pp. 272-281
    • Hickey, W.F.1    Cohen, J.A.2    Burns, J.B.3
  • 39
    • 0025015655 scopus 로고
    • Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages
    • Huitinga I, van Rooijen N, de Groot CJ, Uitdehaag BM, Dijkstra CD (1990) Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages. J Exp Med 172:1025-1033.
    • (1990) J Exp Med , vol.172 , pp. 1025-1033
    • Huitinga, I.1    Van Rooijen, N.2    De Groot, C.J.3    Uitdehaag, B.M.4    Dijkstra, C.D.5
  • 40
    • 0038722051 scopus 로고    scopus 로고
    • Effects of cyclosporin-A on immune response, tissue protection and motor function of rats subjected to spinal cord injury
    • Ibarra A, Correa D, Willms K, Merchant MT, Gui, zar-Sahagun G, Grijalva I, Madrazo I (2003) Effects of cyclosporin-A on immune response, tissue protection and motor function of rats subjected to spinal cord injury. Brain Res 979:165-178.
    • (2003) Brain Res , vol.979 , pp. 165-178
    • Ibarra, A.1    Correa, D.2    Willms, K.3    Merchant, M.T.4    Gui5    Zar-Sahagun, G.6    Grijalva, I.7    Madrazo, I.8
  • 42
    • 0033791462 scopus 로고    scopus 로고
    • Induction of a non-encephalitogenic type 2 T helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebo-controlled, randomized phase II trial
    • The Altered Peptide Ligand in Relapsing MS Study Group
    • Kappos L, Comi G, Panitch H, Oger J, Antel J, Conlon P, Steinman L (2000) Induction of a non-encephalitogenic type 2 T helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebo-controlled, randomized phase II trial. The Altered Peptide Ligand in Relapsing MS Study Group. Nat Med 6:1176-1182.
    • (2000) Nat Med , vol.6 , pp. 1176-1182
    • Kappos, L.1    Comi, G.2    Panitch, H.3    Oger, J.4    Antel, J.5    Conlon, P.6    Steinman, L.7
  • 44
    • 0037180556 scopus 로고    scopus 로고
    • Neuroprotective autoimmunity: Naturally occurring CD4+CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous system
    • Kipnis J, Mizrahi T, Hauben E, Shaked I, Shevach E, Schwartz M (2002) Neuroprotective autoimmunity: naturally occurring CD4+CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous system. Proc Natl Acad Sci USA 99:15620-15625.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 15620-15625
    • Kipnis, J.1    Mizrahi, T.2    Hauben, E.3    Shaked, I.4    Shevach, E.5    Schwartz, M.6
  • 45
    • 0343417081 scopus 로고    scopus 로고
    • Immunologically induced electrophysiological dysfunction: Implications for inflammatory diseases of the CNS and PNS
    • Koller H, Siebler M, Hartung H-P (1997) Immunologically induced electrophysiological dysfunction: implications for inflammatory diseases of the CNS and PNS. Prog Neurobiol 52:1-26.
    • (1997) Prog Neurobiol , vol.52 , pp. 1-26
    • Koller, H.1    Siebler, M.2    Hartung, H.-P.3
  • 47
    • 0034680965 scopus 로고    scopus 로고
    • Co-induction of HSP70 and heme oxygenase-1 in macrophages and glia after spinal cord contusion in the rat
    • Mautes AE, Noble LJ (2000) Co-induction of HSP70 and heme oxygenase-1 in macrophages and glia after spinal cord contusion in the rat. Brain Res 883:233-237.
    • (2000) Brain Res , vol.883 , pp. 233-237
    • Mautes, A.E.1    Noble, L.J.2
  • 48
    • 0034842960 scopus 로고    scopus 로고
    • Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes
    • Medana I, Martinic MA, Wekerle H, Neumann H (2001) Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes. Am J Pathol 159:809-815.
    • (2001) Am J Pathol , vol.159 , pp. 809-815
    • Medana, I.1    Martinic, M.A.2    Wekerle, H.3    Neumann, H.4
  • 49
    • 0023189689 scopus 로고
    • Assessment of spinal cord injury by counting corticospinal and rubrospinal neurons
    • Midha R, Fehlings MG, Tator CH, Saint-Cyr JA, Guha A (1987) Assessment of spinal cord injury by counting corticospinal and rubrospinal neurons. Brain Res 410:299-308.
    • (1987) Brain Res , vol.410 , pp. 299-308
    • Midha, R.1    Fehlings, M.G.2    Tator, C.H.3    Saint-Cyr, J.A.4    Guha, A.5
  • 50
    • 0033049143 scopus 로고    scopus 로고
    • Autoimmune T-cells protect neurons from secondary degeneration after central nervous system axotomy
    • Moalem G, Leibowitz-Amit R, Yoles E, Mor F, Cohen IR, Schwartz M (1999) Autoimmune T-cells protect neurons from secondary degeneration after central nervous system axotomy. Nat Med 5:49-55.
    • (1999) Nat Med , vol.5 , pp. 49-55
    • Moalem, G.1    Leibowitz-Amit, R.2    Yoles, E.3    Mor, F.4    Cohen, I.R.5    Schwartz, M.6
  • 52
    • 0026742832 scopus 로고
    • Facial nerve transection causes expansion of myelin autoreactive T cells in regional lymph nodes and T cell homing to the facial nucleus
    • Olsson T, Diener P, Ljungdahl A, Hojeberg B, van der Meide PH, Kristensson K (1992) Facial nerve transection causes expansion of myelin autoreactive T cells in regional lymph nodes and T cell homing to the facial nucleus. Autoimmun 13:117-126.
    • (1992) Autoimmun , vol.13 , pp. 117-126
    • Olsson, T.1    Diener, P.2    Ljungdahl, A.3    Hojeberg, B.4    Van Der Meide, P.H.5    Kristensson, K.6
  • 53
    • 0027265568 scopus 로고
    • Autoreactive T and B cell responses to myelin antigens after diagnostic sural nerve biopsy
    • Olsson T, Sun JB, Solders G, Xiao BG, Hojeberg B, Ekre HP, Link H (1993) Autoreactive T and B cell responses to myelin antigens after diagnostic sural nerve biopsy. J Neurol Sci 117:130-139.
    • (1993) J Neurol Sci , vol.117 , pp. 130-139
    • Olsson, T.1    Sun, J.B.2    Solders, G.3    Xiao, B.G.4    Hojeberg, B.5    Ekre, H.P.6    Link, H.7
  • 54
    • 0025188659 scopus 로고
    • Myelin basic protein-specific T lymphocyte fines from MS patients and healthy individuals
    • Pette M, Fujita K, Kitze B, Whitaker JN, Albert E, Kappos L, Wekerle H (1990) Myelin basic protein-specific T lymphocyte fines from MS patients and healthy individuals. Neurology 40:1770-1776.
    • (1990) Neurology , vol.40 , pp. 1770-1776
    • Pette, M.1    Fujita, K.2    Kitze, B.3    Whitaker, J.N.4    Albert, E.5    Kappos, L.6    Wekerle, H.7
  • 55
    • 0029739941 scopus 로고    scopus 로고
    • Concept of autoimmunity following spinal cord injury: Possible roles for T lymphocytes in the traumatized central nervous system
    • Popovich PG, Stokes BT, Whitacre CC (1996) Concept of autoimmunity following spinal cord injury: possible roles for T lymphocytes in the traumatized central nervous system. J Neurosci Res 45:349-363.
    • (1996) J Neurosci Res , vol.45 , pp. 349-363
    • Popovich, P.G.1    Stokes, B.T.2    Whitacre, C.C.3
  • 56
    • 0031013236 scopus 로고    scopus 로고
    • The cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats
    • Popovich PG, Wei P, Stokes BT (1997) The cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats. J Comp Neurol 377:443-464.
    • (1997) J Comp Neurol , vol.377 , pp. 443-464
    • Popovich, P.G.1    Wei, P.2    Stokes, B.T.3
  • 57
    • 0015065642 scopus 로고
    • Studies of immunological reactions after brain injury. II. Antibodies against brain tissue lipids after blunt head injury in man
    • Prochazka M, Voltnerova M, Stefan J (1971) Studies of immunological reactions after brain injury. II. Antibodies against brain tissue lipids after blunt head injury in man. Int Surg 55:322-326.
    • (1971) Int Surg , vol.55 , pp. 322-326
    • Prochazka, M.1    Voltnerova, M.2    Stefan, J.3
  • 58
    • 0344084249 scopus 로고    scopus 로고
    • Heat shock proteins (HSP) for immunotherapy of rheumatoid arthritis (RA)
    • Puga Yung GL, Le TD, Roord S, Prakken B, Albani S (2003) Heat shock proteins (HSP) for immunotherapy of rheumatoid arthritis (RA). Inflamm Res 52:443-451.
    • (2003) Inflamm Res , vol.52 , pp. 443-451
    • Puga Yung, G.L.1    Le, T.D.2    Roord, S.3    Prakken, B.4    Albani, S.5
  • 59
    • 34547907306 scopus 로고
    • Observations on attempts to produce disseminated encephalomyelitis in monkeys
    • Rivers TM, Sprunt DH, Berry GP (1933) Observations on attempts to produce disseminated encephalomyelitis in monkeys. J Exp Med 58:39-53.
    • (1933) J Exp Med , vol.58 , pp. 39-53
    • Rivers, T.M.1    Sprunt, D.H.2    Berry, G.P.3
  • 60
    • 0017650830 scopus 로고
    • Objective clinical assessment of motor function after experimental spinal cord injury in the rat
    • Rivlin AS, Tator CH (1977) Objective clinical assessment of motor function after experimental spinal cord injury in the rat. J Neurosurg 47:577-581.
    • (1977) J Neurosurg , vol.47 , pp. 577-581
    • Rivlin, A.S.1    Tator, C.H.2
  • 61
    • 0034966787 scopus 로고    scopus 로고
    • Protective autoimmunity: Regulation and prospects for vaccination after brain and spinal cord injuries
    • Schwartz M, Kipnis J (2001) Protective autoimmunity: regulation and prospects for vaccination after brain and spinal cord injuries. Trends Mol Med 7:252-258.
    • (2001) Trends Mol Med , vol.7 , pp. 252-258
    • Schwartz, M.1    Kipnis, J.2
  • 62
    • 0035866039 scopus 로고    scopus 로고
    • Beneficial immune activity after CNS injury: Prospects for vaccination
    • Schwartz M, Moalem G (2001) Beneficial immune activity after CNS injury: prospects for vaccination. J Neuroimmunol 113:185-192.
    • (2001) J Neuroimmunol , vol.113 , pp. 185-192
    • Schwartz, M.1    Moalem, G.2
  • 63
    • 0032706594 scopus 로고    scopus 로고
    • The remedy may lie in ourselves: Prospects for immune cell therapy in central nervous system protection and repair
    • Schwartz M, Cohen I, Lazarov-Spiegler O, Moalem G, Yoles E (1999) The remedy may lie in ourselves: prospects for immune cell therapy in central nervous system protection and repair. J Mol Med 77:713-717.
    • (1999) J Mol Med , vol.77 , pp. 713-717
    • Schwartz, M.1    Cohen, I.2    Lazarov-Spiegler, O.3    Moalem, G.4    Yoles, E.5
  • 64
    • 4243562216 scopus 로고    scopus 로고
    • Exacerbation of facial motoneuron loss after facial nerve transection in severe combined immunodefiecient (scid) mice
    • Serpe CJ, Kohm AP, Huppenbauer CB, Sanders VM, Jones KJ (1999) Exacerbation of facial motoneuron loss after facial nerve transection in severe combined immunodefiecient (scid) mice. J Neurosci 19:1-5.
    • (1999) J Neurosci , vol.19 , pp. 1-5
    • Serpe, C.J.1    Kohm, A.P.2    Huppenbauer, C.B.3    Sanders, V.M.4    Jones, K.J.5
  • 65
    • 0020663787 scopus 로고
    • Origin of the rubrospinal tract in neonatal, developing, and mature rats
    • Shieh JY, Leong SK, Wong WC (1983) Origin of the rubrospinal tract in neonatal, developing, and mature rats. J Comp Neurol 214:79-86.
    • (1983) J Comp Neurol , vol.214 , pp. 79-86
    • Shieh, J.Y.1    Leong, S.K.2    Wong, W.C.3
  • 66
    • 0029939467 scopus 로고    scopus 로고
    • Multiple sclerosis: A coordinated immunological attack against myelin in the central nervous system
    • Steinman L (1996) Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system. Cell 85:299-302.
    • (1996) Cell , vol.85 , pp. 299-302
    • Steinman, L.1
  • 67
    • 0037882036 scopus 로고    scopus 로고
    • Optic neuritis, a new variant of experimental encephalomyelitis, a durable model for all seasons, now in its seventieth year
    • Steinman L (2003) Optic neuritis, a new variant of experimental encephalomyelitis, a durable model for all seasons, now in its seventieth year. J Exp Med 197:1065-1071.
    • (2003) J Exp Med , vol.197 , pp. 1065-1071
    • Steinman, L.1
  • 68
    • 0021234096 scopus 로고
    • The unbiased estimation of number and sizes of arbitrary particles using the disector
    • Sterio DC (1984) The unbiased estimation of number and sizes of arbitrary particles using the disector. J Microsc 134:127-136.
    • (1984) J Microsc , vol.134 , pp. 127-136
    • Sterio, D.C.1
  • 69
    • 0023579149 scopus 로고
    • Morphometric and experimental studies of the red nucleus in the albino rat
    • Strominger RN, McGiffen JE, Strominger NL (1987) Morphometric and experimental studies of the red nucleus in the albino rat. Anat Rec 219:420-428.
    • (1987) Anat Rec , vol.219 , pp. 420-428
    • Strominger, R.N.1    McGiffen, J.E.2    Strominger, N.L.3
  • 70
    • 0014813514 scopus 로고
    • Purification of an organ-specific thermo-stable antigen found in bovine brain
    • Swanborg RH, Shulman S (1970) Purification of an organ-specific thermo-stable antigen found in bovine brain. Immunology 19:31-40.
    • (1970) Immunology , vol.19 , pp. 31-40
    • Swanborg, R.H.1    Shulman, S.2
  • 72
    • 0344305587 scopus 로고    scopus 로고
    • Interferon-gamma induces characteristics of central sensitization in spinal dorsal horn neurons in vitro
    • Vikman KS, Hill RH, Backstrom E, Robertson B, Kristensson K (2003) Interferon-gamma induces characteristics of central sensitization in spinal dorsal horn neurons in vitro. Pain 106:241-251.
    • (2003) Pain , vol.106 , pp. 241-251
    • Vikman, K.S.1    Hill, R.H.2    Backstrom, E.3    Robertson, B.4    Kristensson, K.5
  • 73
    • 0028238201 scopus 로고
    • Clonal expansion and persistence of human T cells specific for an immunodominant myelin basic protein peptide
    • Wucherpfennig KW, Zhang J, Witek C, Matsui M, Modabber Y, Ota K, Hafler DA (1994) Clonal expansion and persistence of human T cells specific for an immunodominant myelin basic protein peptide. J Immunol 152:5581-5592.
    • (1994) J Immunol , vol.152 , pp. 5581-5592
    • Wucherpfennig, K.W.1    Zhang, J.2    Witek, C.3    Matsui, M.4    Modabber, Y.5    Ota, K.6    Hafler, D.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.