-
2
-
-
0025308617
-
Migration of fetal intestinal intervillous cells in neonatal mice
-
Calvert R, Pother P. Migration of fetal intestinal intervillous cells in neonatal mice. Anat Rec 1990;227:199-206.
-
(1990)
Anat Rec
, vol.227
, pp. 199-206
-
-
Calvert, R.1
Pother, P.2
-
3
-
-
0023780022
-
Development of the pattern of cell renewal in the crypt-villus unit of chimaeric mouse small intestine
-
Schmidt GH, Winton DJ, Ponder BA. Development of the pattern of cell renewal in the crypt-villus unit of chimaeric mouse small intestine. Development 1988;103:785-790.
-
(1988)
Development
, vol.103
, pp. 785-790
-
-
Schmidt, G.H.1
Winton, D.J.2
Ponder, B.A.3
-
5
-
-
0036066584
-
Gastrointestinal stem cells
-
Brittan M, Wright NA. Gastrointestinal stem cells. J Pathol 2002;197:492-509.
-
(2002)
J Pathol
, vol.197
, pp. 492-509
-
-
Brittan, M.1
Wright, N.A.2
-
6
-
-
0032897996
-
Clonal analysis of mouse intestinal epithelial progenitors
-
Bjerknes M, Cheng H. Clonal analysis of mouse intestinal epithelial progenitors. Gastroenterology 1999;116:7-14.
-
(1999)
Gastroenterology
, vol.116
, pp. 7-14
-
-
Bjerknes, M.1
Cheng, H.2
-
7
-
-
0027424646
-
Chimeric-transgenic mice represent a powerful tool for studying how the proliferation and differentiation programs of intestinal epithelial cell lineages are regulated
-
Hermiston ML, Green RP, Gordon JI. Chimeric-transgenic mice represent a powerful tool for studying how the proliferation and differentiation programs of intestinal epithelial cell lineages are regulated. Proc Natl Acad Sci USA 1993;90:8866-8870.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 8866-8870
-
-
Hermiston, M.L.1
Green, R.P.2
Gordon, J.I.3
-
8
-
-
0037453008
-
X-inactivation patch size in human female tissue confounds the assessment of tumor clonality
-
Novelli M, Cossu A, Oukrif D, Quaglia A, Lakhani S, Poul- som R, et al. X-inactivation patch size in human female tissue confounds the assessment of tumor clonality. Proc Natl Acad Sci USA 2003;100:3311-3314.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3311-3314
-
-
Novelli, M.1
Cossu, A.2
Oukrif, D.3
Quaglia, A.4
Lakhani, S.5
Poul- som, R.6
-
9
-
-
0026001002
-
Use of transgenic mice to infer the biological properties of small intestinal stem cells and to examine the lineage relationships of their descendants
-
Roth KA, Hermiston ML, Gordon JI. Use of transgenic mice to infer the biological properties of small intestinal stem cells and to examine the lineage relationships of their descendants. Proc NatlAcadSci USA 1991;88:9407-9411.
-
(1991)
Proc NatlAcadSci USA
, vol.88
, pp. 9407-9411
-
-
Roth, K.A.1
Hermiston, M.L.2
Gordon, J.I.3
-
11
-
-
0012872309
-
Identification of a putative intestinal stem cell and early lineage marker; musashi-1
-
Potten CS, Booth C, Tudor GL, Booth D, Brady G, Hurley P, et al. Identification of a putative intestinal stem cell and early lineage marker; musashi-1. Differentiation 2003;71:28-41.
-
(2003)
Differentiation
, vol.71
, pp. 28-41
-
-
Potten, C.S.1
Booth, C.2
Tudor, G.L.3
Booth, D.4
Brady, G.5
Hurley, P.6
-
12
-
-
0036591968
-
Intestinal stem cells protect their genome by selective segregation oftemplate DNA strands
-
Potten CS, Owen G, Booth D. Intestinal stem cells protect their genome by selective segregation oftemplate DNA strands. JCell Sci 2002;115:2381-2388.
-
(2002)
JCell Sci
, vol.115
, pp. 2381-2388
-
-
Potten, C.S.1
Owen, G.2
Booth, D.3
-
13
-
-
35548974423
-
Identification of stem cells in small intestine and colon by marker gene Lgr5
-
Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, et al. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 2007;449:1003-1007.
-
(2007)
Nature
, vol.449
, pp. 1003-1007
-
-
Barker, N.1
van Es, J.H.2
Kuipers, J.3
Kujala, P.4
van den Born, M.5
Cozijnsen, M.6
-
14
-
-
0016358918
-
Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. I. Columnar cell
-
Cheng H, Leblond CP. Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. I. Columnar cell. Am J Anat 1974;141:461-479.
-
(1974)
Am J Anat
, vol.141
, pp. 461-479
-
-
Cheng, H.1
Leblond, C.P.2
-
15
-
-
0019509229
-
The stem-cell zone of the small intestinal epithelium. IV. Effects of resecting 30% of the small intestine
-
Bjerknes M, Cheng H. The stem-cell zone of the small intestinal epithelium. IV. Effects of resecting 30% of the small intestine. Am J Anat 1981;160:93-103.
-
(1981)
Am J Anat
, vol.160
, pp. 93-103
-
-
Bjerknes, M.1
Cheng, H.2
-
16
-
-
0037472805
-
Candidate markers for stem and early progenitor cells, Musashi-1 and Hes1, are expressed in crypt base columnar cells of mouse small intestine
-
Kayahara T, Sawada M, Takaishi S, Fukui H, Seno H, Fukuzawa H, et al. Candidate markers for stem and early progenitor cells, Musashi-1 and Hes1, are expressed in crypt base columnar cells of mouse small intestine. FEBS Lett 2003;535:131-135.
-
(2003)
FEBS Lett
, vol.535
, pp. 131-135
-
-
Kayahara, T.1
Sawada, M.2
Takaishi, S.3
Fukui, H.4
Seno, H.5
Fukuzawa, H.6
-
17
-
-
85120096775
-
-
Sureban SM, May R, George RJ, Dieckgraefe BK, McLeod HL, Ramalingam S, et al. Knockdown of RNA binding protein Musashi-1 leads to tumor regression in vivo. Gastroenterology 2008;134:1448-1458.e1442.
-
Sureban SM, May R, George RJ, Dieckgraefe BK, McLeod HL, Ramalingam S, et al. Knockdown of RNA binding protein Musashi-1 leads to tumor regression in vivo. Gastroenterology 2008;134:1448-1458.e1442.
-
-
-
-
18
-
-
0036537894
-
Musashi: A translational regulator of cell fate
-
Okano H, Imai T, Okabe M. Musashi: a translational regulator of cell fate. J Cell Sci 2002;115:1355-1359.
-
(2002)
J Cell Sci
, vol.115
, pp. 1355-1359
-
-
Okano, H.1
Imai, T.2
Okabe, M.3
-
19
-
-
46249128798
-
Bmi1 is expressed in vivo in intestinal stem cells
-
Sangiorgi E, Capecchi MR. Bmi1 is expressed in vivo in intestinal stem cells. Nat Genet 2008;40:915-920.
-
(2008)
Nat Genet
, vol.40
, pp. 915-920
-
-
Sangiorgi, E.1
Capecchi, M.R.2
-
20
-
-
36549004644
-
Tracking down the stem cells of the intestine: Strategies to identify adult stem cells
-
Barker N, Clevers H. Tracking down the stem cells of the intestine: strategies to identify adult stem cells. Gastroenterology 2007;133:1755-1760.
-
(2007)
Gastroenterology
, vol.133
, pp. 1755-1760
-
-
Barker, N.1
Clevers, H.2
-
21
-
-
0029781509
-
Functional interaction of ß -catenin with the transcription factor LEF-1
-
Behrens J, von Kries JP, Kuhl M, Bruhn L, Wedlich D, Grosschedl R, et al. Functional interaction of ß -catenin with the transcription factor LEF-1. Nature 1996;382:638-642.
-
(1996)
Nature
, vol.382
, pp. 638-642
-
-
Behrens, J.1
von Kries, J.P.2
Kuhl, M.3
Bruhn, L.4
Wedlich, D.5
Grosschedl, R.6
-
22
-
-
0025938038
-
Identification and characterization of the familial adenomatous polyposis coli gene
-
Groden J, Thliveris A, Samowitz W, Carlson M, Gelbert L, Albertsen H, et al. Identification and characterization of the familial adenomatous polyposis coli gene. Cell 1991;66:589-600.
-
(1991)
Cell
, vol.66
, pp. 589-600
-
-
Groden, J.1
Thliveris, A.2
Samowitz, W.3
Carlson, M.4
Gelbert, L.5
Albertsen, H.6
-
23
-
-
0025817880
-
Identification of FAP locus genes from chromosome 5q21
-
Kinzler KW, Nilbert MC, Su LK, Vogelstein B, Bryan TM, Levy DB, et al. Identification of FAP locus genes from chromosome 5q21. Science 1991;253:661-665.
-
(1991)
Science
, vol.253
, pp. 661-665
-
-
Kinzler, K.W.1
Nilbert, M.C.2
Su, L.K.3
Vogelstein, B.4
Bryan, T.M.5
Levy, D.B.6
-
25
-
-
0030949463
-
Activation of ß-catenin-Tcf signaling in colon cancer by mutations in ß-catenin or APC [see comments]
-
Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogel- stein B, et al. Activation of ß-catenin-Tcf signaling in colon cancer by mutations in ß-catenin or APC [see comments]. Science 1997;275:1787-1790.
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
Barker, N.4
Clevers, H.5
Vogel- stein, B.6
-
26
-
-
0028987249
-
Regulation of intracellular ß-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
-
Munemitsu S, Albert I, Souza B, Rubinfeld B, Polakis P. Regulation of intracellular ß-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. Proc Natl Acad Sci USA 1995;92:3046- 3050.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3046-3050
-
-
Munemitsu, S.1
Albert, I.2
Souza, B.3
Rubinfeld, B.4
Polakis, P.5
-
27
-
-
0029664368
-
Binding of GSK3ß to the APC-ß-catenin complex and regulation of complex assembly
-
Rubinfeld B, Albert I, Porfiri E, Fiol C, Munemitsu S, Polakis P. Binding of GSK3ß to the APC-ß-catenin complex and regulation of complex assembly. Science 1996;272:1023-1026.
-
(1996)
Science
, vol.272
, pp. 1023-1026
-
-
Rubinfeld, B.1
Albert, I.2
Porfiri, E.3
Fiol, C.4
Munemitsu, S.5
Polakis, P.6
-
28
-
-
0027738023
-
Association of the APC gene product withß-catenin
-
Rubinfeld B, Souza B, Albert I, Muller O, Chamberlain SH, Masiarz FR, et al. Association of the APC gene product withß-catenin. Science 1993;262:1731-1734.
-
(1993)
Science
, vol.262
, pp. 1731-1734
-
-
Rubinfeld, B.1
Souza, B.2
Albert, I.3
Muller, O.4
Chamberlain, S.H.5
Masiarz, F.R.6
-
29
-
-
33847740988
-
Wnt/ß-catenin signaling in cancer stemness and malignant behavior
-
Fodde R, Brabletz T. Wnt/ß-catenin signaling in cancer stemness and malignant behavior. Curr Opin Cell Biol 2007;19:1-9.
-
(2007)
Curr Opin Cell Biol
, vol.19
, pp. 1-9
-
-
Fodde, R.1
Brabletz, T.2
-
30
-
-
17444423289
-
Wnt signaling in the intestinal epithelium: From endoderm to cancer
-
Gregorieff A, Clevers H. Wnt signaling in the intestinal epithelium: from endoderm to cancer. Genes Dev 2005;19:877-890.
-
(2005)
Genes Dev
, vol.19
, pp. 877-890
-
-
Gregorieff, A.1
Clevers, H.2
-
31
-
-
0033731110
-
The Wnt signalling pathway
-
Huelsken J, Behrens J. The Wnt signalling pathway. J Cell Sci 2000;113(20):3545.
-
(2000)
J Cell Sci
, vol.113
, Issue.20
, pp. 3545
-
-
Huelsken, J.1
Behrens, J.2
-
32
-
-
33746808398
-
Wnt/ß-catenin signaling in development and disease
-
Clevers H. Wnt/ß-catenin signaling in development and disease. Cell 2006;127:469-480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
33
-
-
0028567875
-
A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors
-
Fodde R, Edelmann W, Yang K, van Leeuwen C, Carlson C, Renault B, et al. A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors. Proc Natl Acad Sci USA 1994;91:8969-8973.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8969-8973
-
-
Fodde, R.1
Edelmann, W.2
Yang, K.3
van Leeuwen, C.4
Carlson, C.5
Renault, B.6
-
34
-
-
0033230616
-
Intestinal polyposis in mice with a dominant stable mutation of the ß-catenin gene
-
Harada N, Tamai Y, Ishikawa T, Sauer B, Takaku K, Oshima M, et al. Intestinal polyposis in mice with a dominant stable mutation of the ß-catenin gene. EMBO J 1999;18:5931-5942.
-
(1999)
EMBO J
, vol.18
, pp. 5931-5942
-
-
Harada, N.1
Tamai, Y.2
Ishikawa, T.3
Sauer, B.4
Takaku, K.5
Oshima, M.6
-
36
-
-
0029047954
-
Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene
-
Oshima M, Oshima H, Kitagawa K, Kobayashi M, Itakura C, Taketo M. Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene. Proc Natl Acad Sci USA 1995;92:4482-4486.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4482-4486
-
-
Oshima, M.1
Oshima, H.2
Kitagawa, K.3
Kobayashi, M.4
Itakura, C.5
Taketo, M.6
-
37
-
-
0033563226
-
Apc1638T: A mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development
-
Smits R, Kielman MF, Breukel C, Zurcher C, Neufeld K, Jagmohan-Changur S, et al. Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development. Genes Dev 1999;13:1309-1321.
-
(1999)
Genes Dev
, vol.13
, pp. 1309-1321
-
-
Smits, R.1
Kielman, M.F.2
Breukel, C.3
Zurcher, C.4
Neufeld, K.5
Jagmohan-Changur, S.6
-
38
-
-
0035907041
-
ß-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin
-
Huelsken J, Vogel R, Erdmann B, Cotsarelis G, Birchmeier W. ß-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell 2001;105:533-545.
-
(2001)
Cell
, vol.105
, pp. 533-545
-
-
Huelsken, J.1
Vogel, R.2
Erdmann, B.3
Cotsarelis, G.4
Birchmeier, W.5
-
39
-
-
33749065765
-
Tcf3 governs stem cell features and represses cell fate determination in skin
-
Nguyen H, Rendl M, Fuchs E. Tcf3 governs stem cell features and represses cell fate determination in skin. Cell 2006;127:171-183.
-
(2006)
Cell
, vol.127
, pp. 171-183
-
-
Nguyen, H.1
Rendl, M.2
Fuchs, E.3
-
40
-
-
0037737728
-
A role for Wnt signalling in self-renewal of haematopoietic stem cells
-
Reya T, Duncan AW, Ailles L, Domen J, Scherer DC, Willert K, et al. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 2003;423:409-414.
-
(2003)
Nature
, vol.423
, pp. 409-414
-
-
Reya, T.1
Duncan, A.W.2
Ailles, L.3
Domen, J.4
Scherer, D.C.5
Willert, K.6
-
41
-
-
0038517899
-
ß-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system
-
Zechner D, Fujita Y, Hulsken J, Muller T, Walther I, Taketo MM, et al. ß-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system. Dev Biol 2003;258:406-418.
-
(2003)
Dev Biol
, vol.258
, pp. 406-418
-
-
Zechner, D.1
Fujita, Y.2
Hulsken, J.3
Muller, T.4
Walther, I.5
Taketo, M.M.6
-
42
-
-
0036696415
-
Formation of multiple hearts in mice following deletion of ß-catenin in the embryonic endoderm
-
Lickert H, Kutsch S, Kanzler B, Tamai Y, Taketo MM, Kem-ler R. Formation of multiple hearts in mice following deletion of ß-catenin in the embryonic endoderm. Dev Cell 2002;3:171-181.
-
(2002)
Dev Cell
, vol.3
, pp. 171-181
-
-
Lickert, H.1
Kutsch, S.2
Kanzler, B.3
Tamai, Y.4
Taketo, M.M.5
Kem-ler, R.6
-
43
-
-
0031848068
-
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
-
Korinek V, Barker N, Moerer P, van Donselaar E, Huls G, Peters PJ, et al. Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat Genet 1998;19:379-383.
-
(1998)
Nat Genet
, vol.19
, pp. 379-383
-
-
Korinek, V.1
Barker, N.2
Moerer, P.3
van Donselaar, E.4
Huls, G.5
Peters, P.J.6
-
44
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway [see comments]
-
He TC, Sparks AB, Rago C, Hermeking H, Zawel L, da Costa LT, et al. Identification of c-MYC as a target of the APC pathway [see comments]. Science 1998;281:1509-1512.
-
(1998)
Science
, vol.281
, pp. 1509-1512
-
-
He, T.C.1
Sparks, A.B.2
Rago, C.3
Hermeking, H.4
Zawel, L.5
da Costa, L.T.6
-
45
-
-
0033545845
-
Thecyclin D1 gene is a target of the ß-catenin/LEF-1 pathway
-
Shtutman M, Zhurinsky J, Simcha I, Albanese C, D'Amico M, Pestell R, et al.Thecyclin D1 gene is a target of the ß-catenin/LEF-1 pathway. Proc Natl Acad Sci USA 1999;96:5522-5527.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 5522-5527
-
-
Shtutman, M.1
Zhurinsky, J.2
Simcha, I.3
Albanese, C.4
D'Amico, M.5
Pestell, R.6
-
46
-
-
0033119801
-
ß-Catenin regulates expression of cyclin D1 in colon carcinoma cells
-
Tetsu O, McCormick F. ß-Catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999;398:422-426.
-
(1999)
Nature
, vol.398
, pp. 422-426
-
-
Tetsu, O.1
McCormick, F.2
-
47
-
-
18644376279
-
ß-Catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB
-
Batlle E, Henderson JT, Beghtel H, van den Born MM, Sancho E, Huls G, et al. ß-Catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB. Cell 2002;111:251-263.
-
(2002)
Cell
, vol.111
, pp. 251-263
-
-
Batlle, E.1
Henderson, J.T.2
Beghtel, H.3
van den Born, M.M.4
Sancho, E.5
Huls, G.6
-
48
-
-
0032884884
-
ß-Catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer
-
Brabletz T, Jung A, Dag S, Hlubek F, Kirchner T. ß-Catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer. Am JPathol 1999;155:1033-1038.
-
(1999)
Am JPathol
, vol.155
, pp. 1033-1038
-
-
Brabletz, T.1
Jung, A.2
Dag, S.3
Hlubek, F.4
Kirchner, T.5
-
49
-
-
0033529126
-
The metalloproteinase Matrilysin is a target of ß-catenin transactivation in intestinaltumors
-
Crawford HC, Fingleton BM, Rudolph-Owen LA, Heppner Goss KJ, Rubinfeld B, Polakis P, et al. The metalloproteinase Matrilysin is a target of ß-catenin transactivation in intestinaltumors. Oncogene 1999;18:2883-2891.
-
(1999)
Oncogene
, vol.18
, pp. 2883-2891
-
-
Crawford, H.C.1
Fingleton, B.M.2
Rudolph-Owen, L.A.3
Heppner Goss, K.J.4
Rubinfeld, B.5
Polakis, P.6
-
50
-
-
20244364236
-
Wnt signalling induces maturation of Paneth cells in intestinal crypts
-
van Es JH, Jay P, Gregorieff A, van Gijn ME, Jonkheer S, Hatzis P, et al. Wnt signalling induces maturation of Paneth cells in intestinal crypts. Nat Cell Biol 2005;7:381-386.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 381-386
-
-
van Es, J.H.1
Jay, P.2
Gregorieff, A.3
van Gijn, M.E.4
Jonkheer, S.5
Hatzis, P.6
-
51
-
-
0035890760
-
Expression of the invasion factor laminin γ 2 in colorectal carcinomas is regulated by ß-catenin
-
Hlubek F, Jung A, Kotzor N, Kirchner T, Brabletz T. Expression of the invasion factor laminin γ 2 in colorectal carcinomas is regulated by ß-catenin. Cancer Res 2001;61:8089-8093.
-
(2001)
Cancer Res
, vol.61
, pp. 8089-8093
-
-
Hlubek, F.1
Jung, A.2
Kotzor, N.3
Kirchner, T.4
Brabletz, T.5
-
52
-
-
0345599013
-
Autoregulation of E-cadherin expression by cadherin-cadherin interactions: The roles of ß-catenin signaling, Slug, and MAPK
-
Conacci-Sorrell M, Simcha I, Ben-Yedidia T, Blechman J, Savagner P, Ben-Ze'ev A. Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of ß-catenin signaling, Slug, and MAPK. J Cell Biol 2003;163:847-857.
-
(2003)
J Cell Biol
, vol.163
, pp. 847-857
-
-
Conacci-Sorrell, M.1
Simcha, I.2
Ben-Yedidia, T.3
Blechman, J.4
Savagner, P.5
Ben-Ze'ev, A.6
-
53
-
-
33644513730
-
Beyond PTEN mutations: The PI3K pathway as an integrator of multiple inputs during tumorigenesis
-
Cully M, You H, Levine AJ, Mak TW. Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis. Nat Rev Cancer 2006;6:184-192.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 184-192
-
-
Cully, M.1
You, H.2
Levine, A.J.3
Mak, T.W.4
-
54
-
-
23844445836
-
Colorectal cancer: Mutations in a signalling pathway
-
Parsons DW, Wang TL, Samuels Y, Bardelli A, Cummins JM, DeLong L, et al. Colorectal cancer: mutations in a signalling pathway. Nature 2005;436:792.
-
(2005)
Nature
, vol.436
, pp. 792
-
-
Parsons, D.W.1
Wang, T.L.2
Samuels, Y.3
Bardelli, A.4
Cummins, J.M.5
DeLong, L.6
-
55
-
-
6944224156
-
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-ß-catenin signaling
-
He XC, Zhang J, Tong WG, Tawfik O, Ross J, Scoville DH, et al. BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-ß-catenin signaling. Nat Genet 2004;36:1117-1121.
-
(2004)
Nat Genet
, vol.36
, pp. 1117-1121
-
-
He, X.C.1
Zhang, J.2
Tong, W.G.3
Tawfik, O.4
Ross, J.5
Scoville, D.H.6
-
56
-
-
33846600427
-
PTEN-deficient intestinal stem cells initiate intestinal polyposis
-
He XC, Yin T, Grindley JC, Tian Q, Sato T, Tao WA, et al. PTEN-deficient intestinal stem cells initiate intestinal polyposis. Nat Genet 2007;39:189-198.
-
(2007)
Nat Genet
, vol.39
, pp. 189-198
-
-
He, X.C.1
Yin, T.2
Grindley, J.C.3
Tian, Q.4
Sato, T.5
Tao, W.A.6
-
57
-
-
0035844886
-
Tumor suppressor PTEN inhibits nuclear accumulation of ß-catenin and T ceMymphoid enhancer factor 1-mediated transcriptional activation
-
Persad S, Troussard AA, McPhee TR, Mulholland DJ, Dedhar S. Tumor suppressor PTEN inhibits nuclear accumulation of ß-catenin and T ceMymphoid enhancer factor 1-mediated transcriptional activation. J Cell Biol 2001;153:1161-1174.
-
(2001)
J Cell Biol
, vol.153
, pp. 1161-1174
-
-
Persad, S.1
Troussard, A.A.2
McPhee, T.R.3
Mulholland, D.J.4
Dedhar, S.5
-
58
-
-
0036789215
-
PTEN and TNFα regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kB-dependent pathway
-
Kim S, Domon-Dell C, Wang Q, Chung DH, Di Cristofano A, Pandolfi PP, et al. PTEN and TNFα regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kB-dependent pathway. Gastroenterology 2002;123:1163-1178.
-
(2002)
Gastroenterology
, vol.123
, pp. 1163-1178
-
-
Kim, S.1
Domon-Dell, C.2
Wang, Q.3
Chung, D.H.4
Di Cristofano, A.5
Pandolfi, P.P.6
-
59
-
-
0035504887
-
Intracellular BMP signaling regulation in vertebrates: Pathway or network?
-
von Bubnoff A, Cho KW. Intracellular BMP signaling regulation in vertebrates: pathway or network? Dev Biol 2001;239:1-14.
-
(2001)
Dev Biol
, vol.239
, pp. 1-14
-
-
von Bubnoff, A.1
Cho, K.W.2
-
60
-
-
1542618115
-
De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine
-
Haramis AP, Begthel H, van den Born M, van Es J, Jonkheer S, Offerhaus GJ, et al. De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine. Science 2004;303:1684-1686.
-
(2004)
Science
, vol.303
, pp. 1684-1686
-
-
Haramis, A.P.1
Begthel, H.2
van den Born, M.3
van Es, J.4
Jonkheer, S.5
Offerhaus, G.J.6
-
61
-
-
34548478312
-
Bone morphogenetic protein signaling is essential for terminal differentiation of the intestinal secretory cell lineage
-
Auclair BA, Benoit YD, Rivard N, Mishina Y, Perreault N. Bone morphogenetic protein signaling is essential for terminal differentiation of the intestinal secretory cell lineage. Gastroen- terology 2007;133:887-896.
-
(2007)
Gastroen- terology
, vol.133
, pp. 887-896
-
-
Auclair, B.A.1
Benoit, Y.D.2
Rivard, N.3
Mishina, Y.4
Perreault, N.5
-
62
-
-
0034972978
-
Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis
-
Howe JR, Bair JL, Sayed MG, Anderson ME, Mitros FA, Petersen GM, et al. Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis. Nat Genet 2001;28:184-187.
-
(2001)
Nat Genet
, vol.28
, pp. 184-187
-
-
Howe, J.R.1
Bair, J.L.2
Sayed, M.G.3
Anderson, M.E.4
Mitros, F.A.5
Petersen, G.M.6
-
63
-
-
0032524069
-
Mutations in the SMAD4/DPC4 gene in juvenile polyposis
-
Howe JR, Roth S, Ringold JC, Summers RW, Jarvinen HJ, Sistonen P, et al. Mutations in the SMAD4/DPC4 gene in juvenile polyposis. Science 1998;280:1086-1088.
-
(1998)
Science
, vol.280
, pp. 1086-1088
-
-
Howe, J.R.1
Roth, S.2
Ringold, J.C.3
Summers, R.W.4
Jarvinen, H.J.5
Sistonen, P.6
-
64
-
-
0032039482
-
The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities
-
Hsu DR, Economides AN, Wang X, Eimon PM, Harland RM. The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities. Mol Cell 1998;1:673-683.
-
(1998)
Mol Cell
, vol.1
, pp. 673-683
-
-
Hsu, D.R.1
Economides, A.N.2
Wang, X.3
Eimon, P.M.4
Harland, R.M.5
-
65
-
-
0030598829
-
The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4
-
Zimmerman LB, De Jesus-Escobar JM, Harland RM. The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell 1996;86:599-606.
-
(1996)
Cell
, vol.86
, pp. 599-606
-
-
Zimmerman, L.B.1
De Jesus-Escobar, J.M.2
Harland, R.M.3
-
66
-
-
34848868159
-
Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors
-
Kosinksi C, Vivian SWL, Annie SYC, Ji Z, Coral H, Wai YT, et al. Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors. Proc Natl Acad Sci 2007;104:15418-15423.
-
(2007)
Proc Natl Acad Sci
, vol.104
, pp. 15418-15423
-
-
Kosinksi, C.1
Vivian, S.W.L.2
Annie, S.Y.C.3
Ji, Z.4
Coral, H.5
Wai, Y.T.6
-
67
-
-
0037444213
-
BMP2 exposure results in decreased PTEN protein degradation and increased PTEN levels
-
Waite KA, Eng C. BMP2 exposure results in decreased PTEN protein degradation and increased PTEN levels. Hum Mol Genet 2003;12:679- 684.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 679-684
-
-
Waite, K.A.1
Eng, C.2
-
68
-
-
0141594935
-
From developmental disorder to heritable cancer: It's all in the BMP/TGFß family
-
Waite KA, Eng C. From developmental disorder to heritable cancer: it's all in the BMP/TGFß family. Nat Rev Genet 2003;4:763-773.
-
(2003)
Nat Rev Genet
, vol.4
, pp. 763-773
-
-
Waite, K.A.1
Eng, C.2
-
69
-
-
33747623018
-
Notch signalling: A simple pathway becomes complex
-
Bray SJ. Notch signalling: a simple pathway becomes complex. Nat Rev Mol Cell Biol 2006;7:678-689.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 678-689
-
-
Bray, S.J.1
-
70
-
-
18544404101
-
Control of endodermal endocrine development by Hes-1
-
Jensen J, Pedersen EE, Galante P, Hald J, Heller RS, Ishibashi M, et al. Control of endodermal endocrine development by Hes-1. Nat Genet 2000;24:36-44.
-
(2000)
Nat Genet
, vol.24
, pp. 36-44
-
-
Jensen, J.1
Pedersen, E.E.2
Galante, P.3
Hald, J.4
Heller, R.S.5
Ishibashi, M.6
-
71
-
-
27844485675
-
Notch and Wnt inhibitors as potential new drugs for intestinal neoplastic disease
-
van Es JH, Clevers H. Notch and Wnt inhibitors as potential new drugs for intestinal neoplastic disease. Trends Mol Med 2005;11:496-502.
-
(2005)
Trends Mol Med
, vol.11
, pp. 496-502
-
-
van Es, J.H.1
Clevers, H.2
-
72
-
-
20544460148
-
Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
-
van Es JH, van Gijn ME, Riccio O, van den Born M, Vooijs M, Begthel H, et al.Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 2005;435:959-963.
-
(2005)
Nature
, vol.435
, pp. 959-963
-
-
van Es, J.H.1
van Gijn, M.E.2
Riccio, O.3
van den Born, M.4
Vooijs, M.5
Begthel, H.6
-
73
-
-
0035824487
-
Requirement of Math1 for secretory cell lineage commitment in the mouse intestine
-
Yang Q, Bermingham NA, Finegold MJ, Zoghbi HY. Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science 2001;294:2155-2158.
-
(2001)
Science
, vol.294
, pp. 2155-2158
-
-
Yang, Q.1
Bermingham, N.A.2
Finegold, M.J.3
Zoghbi, H.Y.4
-
74
-
-
48749089743
-
Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2
-
Riccio O, van Gijn ME, Bezdek AC, Pellegrinet L, van Es JH, Zimber-Strobl U, et al. Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2. EMBO Rep 2008;9:377-383.
-
(2008)
EMBO Rep
, vol.9
, pp. 377-383
-
-
Riccio, O.1
van Gijn, M.E.2
Bezdek, A.C.3
Pellegrinet, L.4
van Es, J.H.5
Zimber-Strobl, U.6
-
75
-
-
0030886674
-
Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in β 2/neuroD-deficient mice
-
Naya FJ, Huang HP, Qiu Y, Mutoh H, DeMayo FJ, Leiter AB, et al. Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in β 2/neuroD-deficient mice. Genes Dev 1997;11:2323-2334.
-
(1997)
Genes Dev
, vol.11
, pp. 2323-2334
-
-
Naya, F.J.1
Huang, H.P.2
Qiu, Y.3
Mutoh, H.4
DeMayo, F.J.5
Leiter, A.B.6
-
76
-
-
13944259054
-
Epithelial hedgehog signals pattern the intestinal crypt-villus axis
-
Madison BB, Braunstein K, Kuizon E, Portman K, Qiao XT, Gumucio DL. Epithelial hedgehog signals pattern the intestinal crypt-villus axis. Development 2005;132:279-289.
-
(2005)
Development
, vol.132
, pp. 279-289
-
-
Madison, B.B.1
Braunstein, K.2
Kuizon, E.3
Portman, K.4
Qiao, X.T.5
Gumucio, D.L.6
-
77
-
-
35648977027
-
Hedgehog signaling in development and homeostasis of the gastrointestinal tract
-
van den Brink GR. Hedgehog signaling in development and homeostasis of the gastrointestinal tract. Physiol Rev 2007;87:1343-1375.
-
(2007)
Physiol Rev
, vol.87
, pp. 1343-1375
-
-
van den Brink, G.R.1
-
78
-
-
10744233571
-
Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation
-
van den Brink GR, Bleuming SA, Hardwick JC, Schepman BL, Offerhaus GJ, Keller JJ, et al. Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation. Nat Genet 2004;36:277- 282.
-
(2004)
Nat Genet
, vol.36
, pp. 277-282
-
-
van den Brink, G.R.1
Bleuming, S.A.2
Hardwick, J.C.3
Schepman, B.L.4
Offerhaus, G.J.5
Keller, J.J.6
-
79
-
-
0001003110
-
XTcf-3 transcription factor mediates ß-catenin-induced axis formation in Xenopus embryos
-
Molenaar M, van de Wetering M, Oosterwegel M, Peterson- Maduro J, Godsave S, Korinek V, et al. XTcf-3 transcription factor mediates ß-catenin-induced axis formation in Xenopus embryos. Cell 1996;86:391-399.
-
(1996)
Cell
, vol.86
, pp. 391-399
-
-
Molenaar, M.1
van de Wetering, M.2
Oosterwegel, M.3
Peterson- Maduro, J.4
Godsave, S.5
Korinek, V.6
-
80
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis P. Wnt signaling and cancer. Genes Dev 2000; 1837-1851.
-
(2000)
Genes Dev
, pp. 1837-1851
-
-
Polakis, P.1
-
81
-
-
0026613003
-
Proliferation in human gastrointestinal epithelium using bromodeoxyuridine in vivo: Data for different sites, proximity to a tumour, and polyposis coli [see comments]
-
Potten CS, Kellett M, Rew DA, Roberts SA. Proliferation in human gastrointestinal epithelium using bromodeoxyuridine in vivo: data for different sites, proximity to a tumour, and polyposis coli [see comments]. Gut 1992;33:524-529.
-
(1992)
Gut
, vol.33
, pp. 524-529
-
-
Potten, C.S.1
Kellett, M.2
Rew, D.A.3
Roberts, S.A.4
-
82
-
-
0035577284
-
Computer modeling implicates stem cell overproduction in colon cancer initiation
-
Boman BM, Fields JZ, Bonham-Carter O, Runquist OA. Computer modeling implicates stem cell overproduction in colon cancer initiation. Cancer Res 2001;61:8408-8411.
-
(2001)
Cancer Res
, vol.61
, pp. 8408-8411
-
-
Boman, B.M.1
Fields, J.Z.2
Bonham-Carter, O.3
Runquist, O.A.4
-
83
-
-
7244242266
-
Colonic crypt changes during adenoma development in familial adenomatous polyposis: Immunohistochemical evidence for expansion of the crypt base cell population
-
Boman BM, Walters R, Fields JZ, Kovatich AJ, Zhang T, Isenberg GA, et al. Colonic crypt changes during adenoma development in familial adenomatous polyposis: immunohistochemical evidence for expansion of the crypt base cell population. Am J Pathol 2004;165:1489-1498.
-
(2004)
Am J Pathol
, vol.165
, pp. 1489-1498
-
-
Boman, B.M.1
Walters, R.2
Fields, J.Z.3
Kovatich, A.J.4
Zhang, T.5
Isenberg, G.A.6
-
84
-
-
0035893568
-
Evidence that APC regulates survivin expression: A possible mechanism contributing to the stem cell origin of colon cancer
-
Zhang T, Otevrel T, Gao Z, Ehrlich SM, Fields JZ, Boman BM. Evidence that APC regulates survivin expression: a possible mechanism contributing to the stem cell origin of colon cancer. Cancer Res 2001;61:8664-8667.
-
(2001)
Cancer Res
, vol.61
, pp. 8664-8667
-
-
Zhang, T.1
Otevrel, T.2
Gao, Z.3
Ehrlich, S.M.4
Fields, J.Z.5
Boman, B.M.6
-
85
-
-
31444433936
-
Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission
-
Greaves LC, Preston SL, Tadrous PJ, Taylor RW, Barron MJ, Oukrif D, et al. Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission. Proc Natl Acad Sci USA 2006;103:714-719.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 714-719
-
-
Greaves, L.C.1
Preston, S.L.2
Tadrous, P.J.3
Taylor, R.W.4
Barron, M.J.5
Oukrif, D.6
-
86
-
-
0038079684
-
Bottom-up histogenesis of colorectal adenomas: Origin in the monocryptal adenoma and initial expansion by crypt fission
-
Preston SL, Wong W-M, Chan AO-O, Poulsom R, Jeffery R, Goodlad RA, et al. Bottom-up histogenesis of colorectal adenomas: origin in the monocryptal adenoma and initial expansion by crypt fission. Cancer Res 2003;63:3819-3825.
-
(2003)
Cancer Res
, vol.63
, pp. 3819-3825
-
-
Preston, S.L.1
Wong, W.-M.2
Chan, A.O.-O.3
Poulsom, R.4
Jeffery, R.5
Goodlad, R.A.6
-
87
-
-
0031059349
-
APC mutation and the crypt cycle in murine and human intestine
-
Bjerknes M, Cheng H, Hay K, Gallinger S. APC mutation and the crypt cycle in murine and human intestine. Am J Pathol 1997;150:833-839.
-
(1997)
Am J Pathol
, vol.150
, pp. 833-839
-
-
Bjerknes, M.1
Cheng, H.2
Hay, K.3
Gallinger, S.4
-
88
-
-
0031877446
-
APC in the regulation of intestinal crypt fission
-
Wasan HS, Park HS, Liu KC, Mandir NK, Winnett A, Sasieni P, et al. APC in the regulation of intestinal crypt fission. J Pathol 1998;185:246- 255.
-
(1998)
J Pathol
, vol.185
, pp. 246-255
-
-
Wasan, H.S.1
Park, H.S.2
Liu, K.C.3
Mandir, N.K.4
Winnett, A.5
Sasieni, P.6
-
89
-
-
45549085634
-
Human colon cancer stem cells: A new paradigm in gastrointestinal oncology
-
Boman BM, Huang E. Human colon cancer stem cells: a new paradigm in gastrointestinal oncology. J Clin Oncol 2008;26:2828-2838.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2828-2838
-
-
Boman, B.M.1
Huang, E.2
-
90
-
-
0038498213
-
Survivin and molecular pathogenesis of colorectal cancer
-
Kim PJ, Plescia J, Clevers H, Fearon ER, Altieri DC. Survivin and molecular pathogenesis of colorectal cancer. Lancet 2003;362:205- 209.
-
(2003)
Lancet
, vol.362
, pp. 205-209
-
-
Kim, P.J.1
Plescia, J.2
Clevers, H.3
Fearon, E.R.4
Altieri, D.C.5
-
91
-
-
0000099546
-
Observations on the origin of adenomatous epithelium of the colon. Serial section of minute polyps in familial polyposis
-
Lane N, Lev R. Observations on the origin of adenomatous epithelium of the colon. Serial section of minute polyps in familial polyposis. Cancer 1963;16:751 -764.
-
(1963)
Cancer
, vol.16
, pp. 751-764
-
-
Lane, N.1
Lev, R.2
-
92
-
-
0020357902
-
In vivo measurements in familial polyposis: Kinetics and location of proliferating cells in colonic adenomas
-
Lightdale C, Lipkin M, Deschner E. In vivo measurements in familial polyposis: kinetics and location of proliferating cells in colonic adenomas. Cancer Res 1982;42:4280-4283.
-
(1982)
Cancer Res
, vol.42
, pp. 4280-4283
-
-
Lightdale, C.1
Lipkin, M.2
Deschner, E.3
-
93
-
-
0033870244
-
Expression of nuclear ß-catenin and c-myc is correlated with tumor size but not with proliferative activity of colorectal adenomas
-
Brabletz T, Herrmann K, Jung A, Faller G, Kirchner T. Expression of nuclear ß-catenin and c-myc is correlated with tumor size but not with proliferative activity of colorectal adenomas. Am J Pathol 2000;156:865-870.
-
(2000)
Am J Pathol
, vol.156
, pp. 865-870
-
-
Brabletz, T.1
Herrmann, K.2
Jung, A.3
Faller, G.4
Kirchner, T.5
-
94
-
-
0031727409
-
Nuclear overexpression of the oncoprotein ß -catenin in colorectal cancer is localized predominantly at the invasion front
-
Brabletz T, Jung A, Hermann K, Gunther K, Hohenberger W, Kirchner T. Nuclear overexpression of the oncoprotein ß -catenin in colorectal cancer is localized predominantly at the invasion front. Pathol Res Pract 1998;194:701-704.
-
(1998)
Pathol Res Pract
, vol.194
, pp. 701-704
-
-
Brabletz, T.1
Jung, A.2
Hermann, K.3
Gunther, K.4
Hohenberger, W.5
Kirchner, T.6
-
95
-
-
0033810123
-
Patterning and nuclear ß-catenin expression in the colonic adenoma-carcinoma sequence: Analogies with embryonic gastrulation
-
Kirchner T, Brabletz T. Patterning and nuclear ß-catenin expression in the colonic adenoma-carcinoma sequence: analogies with embryonic gastrulation. Am J Pathol 2000;157:1113-1121.
-
(2000)
Am J Pathol
, vol.157
, pp. 1113-1121
-
-
Kirchner, T.1
Brabletz, T.2
-
96
-
-
22144497081
-
Invasion and metastasis in colorectal cancer: Epithelial- mesenchymal transition, mesenchymal-epithelial transition, stem cells and ß-catenin
-
Brabletz T, Hlubek F, Spaderna S, Schmalhofer O, Hiendlmeyer E, Jung A, et al. Invasion and metastasis in colorectal cancer: epithelial- mesenchymal transition, mesenchymal-epithelial transition, stem cells and ß-catenin. Cells Tissues Organs 2005;179:56-65.
-
(2005)
Cells Tissues Organs
, vol.179
, pp. 56-65
-
-
Brabletz, T.1
Hlubek, F.2
Spaderna, S.3
Schmalhofer, O.4
Hiendlmeyer, E.5
Jung, A.6
-
97
-
-
0036301919
-
ß-catenin and the morphogenesis of colorectal cancer
-
Brabletz T, Jung A, Kirchner T. ß-catenin and the morphogenesis of colorectal cancer. Virchows Arch 2002;441:1 -11.
-
(2002)
Virchows Arch
, vol.441
, pp. 1-11
-
-
Brabletz, T.1
Jung, A.2
Kirchner, T.3
-
98
-
-
0035964349
-
Variable ß-catenin expression in col-orectal cancer indicates a tumor progression driven by the tumor environment
-
Brabletz T, Jung A, Reu S, Porzner M, Hlubek F, Kunz- Schughart L, et al.Variable ß-catenin expression in col-orectal cancer indicates a tumor progression driven by the tumor environment. Proc Natl Acad Sci USA 2001;98:10356-10361.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10356-10361
-
-
Brabletz, T.1
Jung, A.2
Reu, S.3
Porzner, M.4
Hlubek, F.5
Kunz- Schughart, L.6
-
99
-
-
0033145059
-
Regulative development of the sea urchin embryo: Signalling cascades and morphogen gradients
-
Angerer L, Angerer R. Regulative development of the sea urchin embryo: signalling cascades and morphogen gradients. Semin Cell Dev Biol 1999;10:327-334.
-
(1999)
Semin Cell Dev Biol
, vol.10
, pp. 327-334
-
-
Angerer, L.1
Angerer, R.2
-
100
-
-
33750027350
-
Gastrulation: Wnts signal constriction
-
Chisholm AD. Gastrulation: Wnts signal constriction. Curr Biol 2006;16:R874-876.
-
(2006)
Curr Biol
, vol.16
-
-
Chisholm, A.D.1
-
101
-
-
5444233462
-
APC dosage effects in tumorigenesis and stem cell differentiation
-
Gaspar C, Fodde R. APC dosage effects in tumorigenesis and stem cell differentiation. Int J Dev Biol 2004;48:377-386.
-
(2004)
Int J Dev Biol
, vol.48
, pp. 377-386
-
-
Gaspar, C.1
Fodde, R.2
-
102
-
-
33749320834
-
APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression
-
Janssen KP, Alberici P, Fsihi H, Gaspar C, Breukel C, Franken P, et al. APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression. Gastroenterology 2006;131:1096-1109.
-
(2006)
Gastroenterology
, vol.131
, pp. 1096-1109
-
-
Janssen, K.P.1
Alberici, P.2
Fsihi, H.3
Gaspar, C.4
Breukel, C.5
Franken, P.6
-
103
-
-
25444495269
-
Opinion: Migrating cancer stem cells - an integrated concept of malignant tumour progression
-
Brabletz T, Jung A, Spaderna S, Hlubek F, Kirchner T. Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression. Nat Rev Cancer 2005;5:744-749.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 744-749
-
-
Brabletz, T.1
Jung, A.2
Spaderna, S.3
Hlubek, F.4
Kirchner, T.5
-
104
-
-
0035149139
-
The invasion front of human colorectal adenocarcinomas shows co-localization of nuclear ß-catenin, cyclin D(1), and p16(INK4A) and is a region of low proliferation
-
Jung A, Schrauder M, Oswald U, Knoll C, Sellberg P, Palmqvist R, et al. The invasion front of human colorectal adenocarcinomas shows co-localization of nuclear ß-catenin, cyclin D(1), and p16(INK4A) and is a region of low proliferation. Am J Pathol 2001;159:1613-1617.
-
(2001)
Am J Pathol
, vol.159
, pp. 1613-1617
-
-
Jung, A.1
Schrauder, M.2
Oswald, U.3
Knoll, C.4
Sellberg, P.5
Palmqvist, R.6
-
105
-
-
34547141894
-
Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers
-
Mani SA, Yang J, Brooks M, Schwaninger G, Zhou A, Miura N, et al. Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers. Proc Natl Acad Sci USA 2007;104:10069-10074.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 10069-10074
-
-
Mani, S.A.1
Yang, J.2
Brooks, M.3
Schwaninger, G.4
Zhou, A.5
Miura, N.6
-
107
-
-
33644826473
-
Roots and stems: Stem cells in cancer
-
Polyak K, Hahn WC. Roots and stems: stem cells in cancer. Nat Med 2006;12:296-300.
-
(2006)
Nat Med
, vol.12
, pp. 296-300
-
-
Polyak, K.1
Hahn, W.C.2
-
108
-
-
33750339604
-
Cancer stem cells and metastasis: Lethal seeds
-
Wicha MS. Cancer stem cells and metastasis: lethal seeds. Clin Cancer Res 2006;12:5606-5607.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5606-5607
-
-
Wicha, M.S.1
-
109
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997;3:730-737.
-
(1997)
Nat Med
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
110
-
-
30644471961
-
Stem cells in the etiology and treatment of cancer
-
Zhang M, Rosen JM. Stem cells in the etiology and treatment of cancer. Curr Opin Genet Dev 2006;16:60-64.
-
(2006)
Curr Opin Genet Dev
, vol.16
, pp. 60-64
-
-
Zhang, M.1
Rosen, J.M.2
-
111
-
-
33750313208
-
Cancer stem cells - perspectives on current status and future directions: AACR workshop on cancer stem cells
-
Clarke MF, Dick JE, Dirks PB, Eaves CJ, Jamieson CH, Jones DL, et al. Cancer stem cells - perspectives on current status and future directions: AACR workshop on cancer stem cells. Cancer Res 2006;66:9339-9344.
-
(2006)
Cancer Res
, vol.66
, pp. 9339-9344
-
-
Clarke, M.F.1
Dick, J.E.2
Dirks, P.B.3
Eaves, C.J.4
Jamieson, C.H.5
Jones, D.L.6
-
112
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunode-ficient mice
-
O'Brien CA, Pollett A, Gallinger S, Dick JE. A human colon cancer cell capable of initiating tumour growth in immunode-ficient mice. Nature 2007;445:106-110.
-
(2007)
Nature
, vol.445
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
113
-
-
33846095137
-
Identification and expansion of human colon cancer-initiating cells
-
Ricci-Vitiani L, Lombardi DG, Pilozzi E, Biffoni M, Todaro M, Peschle C, et al. Identification and expansion of human colon cancer-initiating cells. Nature 2007;445:111-115.
-
(2007)
Nature
, vol.445
, pp. 111-115
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
Biffoni, M.4
Todaro, M.5
Peschle, C.6
-
114
-
-
0030817282
-
-
Weigmann A, Corbeil D, Hellwig A, Huttner WB. Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells. Proc Natl Acad Sci USA 1997;94:12425-12430.
-
Weigmann A, Corbeil D, Hellwig A, Huttner WB. Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells. Proc Natl Acad Sci USA 1997;94:12425-12430.
-
-
-
-
115
-
-
38049004813
-
CD133: Molecule of the moment
-
Mizrak MBMRA. CD133: molecule of the moment. J Pathol 2008;214:3-9.
-
(2008)
J Pathol
, vol.214
, pp. 3-9
-
-
Mizrak, M.B.M.R.A.1
-
116
-
-
45749102020
-
CD133 expression is not restricted to stem cells, and both CD133 and CD133 metastatic colon cancer cells initiate tumors
-
Shmelkov SV, Butler JM, Hooper AT, Hormigo A, Kushner J, Milde T, et al. CD133 expression is not restricted to stem cells, and both CD133 and CD133 metastatic colon cancer cells initiate tumors. J Clin Invest 2008;118:2111-2120.
-
(2008)
J Clin Invest
, vol.118
, pp. 2111-2120
-
-
Shmelkov, S.V.1
Butler, J.M.2
Hooper, A.T.3
Hormigo, A.4
Kushner, J.5
Milde, T.6
-
117
-
-
34547193404
-
Phenotypic characterization of human colorectal cancer stem cells
-
Dalerba P, Dylla SJ, Park IK, Liu R, Wang X, Cho RW, et al. Phenotypic characterization of human colorectal cancer stem cells. Proc Natl Acad Sci USA 2007;104:10158-10163.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 10158-10163
-
-
Dalerba, P.1
Dylla, S.J.2
Park, I.K.3
Liu, R.4
Wang, X.5
Cho, R.W.6
-
119
-
-
33847686753
-
CD133-positive hepatocellular carcinoma cells possess high capacity for tumorigenicity
-
Yin S, Li J, Hu C, Chen X, Yao M, Yan M, et al. CD133-positive hepatocellular carcinoma cells possess high capacity for tumorigenicity. Int JCancer 2007;120:1444-1450.
-
(2007)
Int JCancer
, vol.120
, pp. 1444-1450
-
-
Yin, S.1
Li, J.2
Hu, C.3
Chen, X.4
Yao, M.5
Yan, M.6
-
120
-
-
34548455927
-
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
-
Hermann PC, Huber SL, Herrler T, Aicher A, Ellwart JW, Guba M, et al. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 2007;1:313-323.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 313-323
-
-
Hermann, P.C.1
Huber, S.L.2
Herrler, T.3
Aicher, A.4
Ellwart, J.W.5
Guba, M.6
-
122
-
-
33847052127
-
Identification of pancreatic cancer stem cells
-
Li C, Heidt DG, Dalerba P, Burant CF, Zhang L, Adsay V, et al. Identification of pancreatic cancer stem cells. Cancer Res 2007;67:1030-1037.
-
(2007)
Cancer Res
, vol.67
, pp. 1030-1037
-
-
Li, C.1
Heidt, D.G.2
Dalerba, P.3
Burant, C.F.4
Zhang, L.5
Adsay, V.6
-
123
-
-
9444265320
-
Gastric cancer originating from bone marrow-derived cells
-
Houghton J, Stoicov C, Nomura S, Rogers AB, Carlson J, Li H, et al. Gastric cancer originating from bone marrow-derived cells. Science 2004;306:1568-1571.
-
(2004)
Science
, vol.306
, pp. 1568-1571
-
-
Houghton, J.1
Stoicov, C.2
Nomura, S.3
Rogers, A.B.4
Carlson, J.5
Li, H.6
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