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Volumn 13, Issue 10, 1999, Pages 1309-1321

Apc1638T: A mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development

Author keywords

Apc; Development; SAMP; Tumorigenesis; catenin

Indexed keywords

BETA CATENIN;

EID: 0033563226     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.13.10.1309     Document Type: Article
Times cited : (193)

References (64)
  • 2
    • 0030614352 scopus 로고    scopus 로고
    • 2-terminal deletion of β-catenin results in stable colocalization of mutant β-catenin with adenomatous polyposis coli protein and altered MDCK cell adhesion
    • 2-terminal deletion of β-catenin results in stable colocalization of mutant β-catenin with adenomatous polyposis coli protein and altered MDCK cell adhesion. J. Cell Biol. 136: 693-706.
    • (1997) J. Cell Biol. , vol.136 , pp. 693-706
    • Barth, A.I.M.1    Pollack, A.L.2    Altschuler, Y.3    Mostov, K.E.4    Nelson, W.J.5
  • 5
    • 0030611667 scopus 로고    scopus 로고
    • Mal3, the fission yeast homologue of the human APC-interacting protein EB-1 is required for microtubule integrity and the maintenance of cell form
    • Beinhauer, J.D., I.M. Hagan, J.H. Hegemann, and U. Fleig. 1997. Mal3, the fission yeast homologue of the human APC-interacting protein EB-1 is required for microtubule integrity and the maintenance of cell form. J. Cell Biol. 139: 717-728.
    • (1997) J. Cell Biol. , vol.139 , pp. 717-728
    • Beinhauer, J.D.1    Hagan, I.M.2    Hegemann, J.H.3    Fleig, U.4
  • 7
    • 0028331667 scopus 로고
    • High levels of expression of the tumor suppressor gene APC during development of the rat central nervous system
    • Bhat R.V., J.M. Baraban, R.C. Johnson, B.A. Eipper, and R.E. Mains. 1994. High levels of expression of the tumor suppressor gene APC during development of the rat central nervous system. J. Neurosci. 14:3059-3071.
    • (1994) J. Neurosci. , vol.14 , pp. 3059-3071
    • Bhat, R.V.1    Baraban, J.M.2    Johnson, R.C.3    Eipper, B.A.4    Mains, R.E.5
  • 8
    • 0016429264 scopus 로고
    • Hormonal influences on the morphogenesis of the preputial gland of embryonic mice
    • Cunha, G.R. 1975. Hormonal influences on the morphogenesis of the preputial gland of embryonic mice. Anat. Rec. 181: 35-54.
    • (1975) Anat. Rec. , vol.181 , pp. 35-54
    • Cunha, G.R.1
  • 9
    • 0016854570 scopus 로고
    • Direct and mediated effects of testosterone: The development of intersexes in sex reversed mosaic mice, heterozygous for testicular feminization
    • Drews, U. 1975. Direct and mediated effects of testosterone: The development of intersexes in sex reversed mosaic mice, heterozygous for testicular feminization. Anat. Embryol. 146: 325-340.
    • (1975) Anat. Embryol. , vol.146 , pp. 325-340
    • Drews, U.1
  • 11
    • 13144266741 scopus 로고    scopus 로고
    • Intestinal trefoil factor controls the expression of the adenomatous polyposis coli-catenin and the E-cadherin-catenin complexes in human colon carcinoma cells
    • Efstathiou, J.A., M. Noda, A. Rowan, C. Dixon, R. Chinery, A. Jawhari, T. Hattori, N.A. Wright, W.F. Bodmer, and M. Pignatelli. 1998. Intestinal trefoil factor controls the expression of the adenomatous polyposis coli-catenin and the E-cadherin-catenin complexes in human colon carcinoma cells. Proc. Natl. Acad. Sci. 95: 3122-3127.
    • (1998) Proc. Natl. Acad. Sci. , vol.95 , pp. 3122-3127
    • Efstathiou, J.A.1    Noda, M.2    Rowan, A.3    Dixon, C.4    Chinery, R.5    Jawhari, A.6    Hattori, T.7    Wright, N.A.8    Bodmer, W.F.9    Pignatelli, M.10
  • 17
    • 0032492954 scopus 로고    scopus 로고
    • Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β
    • Hart, M.J., R. de los Santos, I.N. Albert, B. Rubinfeld, and P. Polakis. 1998. Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β. Curr. Biol. 8: 573-581.
    • (1998) Curr. Biol. , vol.8 , pp. 573-581
    • Hart, M.J.1    De Los Santos, R.2    Albert, I.N.3    Rubinfeld, B.4    Polakis, P.5
  • 20
    • 0031833055 scopus 로고    scopus 로고
    • A new spontaneous mouse mutation of Hoxd13 with a polyalanine expansion and phenotype similar to human synpolydactyly
    • Johnson, K.R., H.O. Sweet, L.R. Donahue, P. Ward-Bailey, R.T. Bronson, and M.T. Davisson. 1998. A new spontaneous mouse mutation of Hoxd13 with a polyalanine expansion and phenotype similar to human synpolydactyly. Hum. Mol. Genet. 7: 1033-1038.
    • (1998) Hum. Mol. Genet. , vol.7 , pp. 1033-1038
    • Johnson, K.R.1    Sweet, H.O.2    Donahue, L.R.3    Ward-Bailey, P.4    Bronson, R.T.5    Davisson, M.T.6
  • 21
    • 0027361020 scopus 로고
    • Dimer formation by an N-terminal coiled coil in the APC protein
    • Joslyn, G., D.S. Richardson, R. White, and T. Alber. 1993. Dimer formation by an N-terminal coiled coil in the APC protein. Proc. Natl. Acad. Sci. 90: 11109-11113.
    • (1993) Proc. Natl. Acad. Sci. , vol.90 , pp. 11109-11113
    • Joslyn, G.1    Richardson, D.S.2    White, R.3    Alber, T.4
  • 24
    • 8544258802 scopus 로고    scopus 로고
    • Cloning and characterization of NE-dlg: A novel human homolog of the Drosophila discs large (dlg) tumor suppressor protein interacts with the APC protein
    • Makino, K., H. Kuwahara, N. Masuko, Y. Nishiyama, T. Morisaki, J.-I. Sasaki, M. Nakao, A. Kuwano, M. Nakata, Y. Ushio, and H. Saya. 1997. Cloning and characterization of NE-dlg: A novel human homolog of the Drosophila discs large (dlg) tumor suppressor protein interacts with the APC protein. Oncogene 14: 2425-2433.
    • (1997) Oncogene , vol.14 , pp. 2425-2433
    • Makino, K.1    Kuwahara, H.2    Masuko, N.3    Nishiyama, Y.4    Morisaki, T.5    Sasaki, J.-I.6    Nakao, M.7    Kuwano, A.8    Nakata, M.9    Ushio, Y.10    Saya, H.11
  • 29
  • 30
    • 0031559910 scopus 로고    scopus 로고
    • The cellular distribution of the adenomatous poliposis coli tumour suppressor protein in neuroblastoma cells is regulated by microtubule dynamics
    • Morrison, E.E., J.M. Askham, P. Clissold, A.F. Markham, and D.M. Meredith. 1997. The cellular distribution of the adenomatous poliposis coli tumour suppressor protein in neuroblastoma cells is regulated by microtubule dynamics. Neuroscience 81: 553-563.
    • (1997) Neuroscience , vol.81 , pp. 553-563
    • Morrison, E.E.1    Askham, J.M.2    Clissold, P.3    Markham, A.F.4    Meredith, D.M.5
  • 31
    • 0025015168 scopus 로고
    • A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
    • Moser, A.R., H.C. Pilot, and W.F. Dove. 1990. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 247: 322-324.
    • (1990) Science , vol.247 , pp. 322-324
    • Moser, A.R.1    Pilot, H.C.2    Dove, W.F.3
  • 33
    • 0032482399 scopus 로고    scopus 로고
    • A cytokinesis checkpoint requiring the yeast homologue of an APC-binding protein
    • Muhua, L., N.R. Adames, M.D. Murphy, C.R. Shields, and J.A. Cooper. 1998. A cytokinesis checkpoint requiring the yeast homologue of an APC-binding protein. Nature 393: 487-491.
    • (1998) Nature , vol.393 , pp. 487-491
    • Muhua, L.1    Adames, N.R.2    Murphy, M.D.3    Shields, C.R.4    Cooper, J.A.5
  • 34
    • 0027930066 scopus 로고
    • The APC gene product associates with microtubules in vivo and promotes their assembly in vitro
    • Munemitsu, S., B. Souza, O. Müller, I. Albert, B. Rubinfeld, and P. Polakis. 1994. The APC gene product associates with microtubules in vivo and promotes their assembly in vitro. Cancer Res. 54: 3676-3681.
    • (1994) Cancer Res. , vol.54 , pp. 3676-3681
    • Munemitsu, S.1    Souza, B.2    Müller, O.3    Albert, I.4    Rubinfeld, B.5    Polakis, P.6
  • 35
    • 0028987249 scopus 로고
    • Regulation of intracellular β-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
    • Munemitsu, S., I. Albert, B. Souza, B. Rubinfeld, and P. Polakis. 1995. Regulation of intracellular β-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. Proc. Natl. Acad. Sci. 92: 3046-3050.
    • (1995) Proc. Natl. Acad. Sci. , vol.92 , pp. 3046-3050
    • Munemitsu, S.1    Albert, I.2    Souza, B.3    Rubinfeld, B.4    Polakis, P.5
  • 36
    • 0027146559 scopus 로고
    • Mutations of the APC (adenomatous polyposis coli) gene
    • Nagase, H., and Y. Nakamura. 1993. Mutations of the APC (adenomatous polyposis coli) gene. Hum. Mutat. 2: 425-434.
    • (1993) Hum. Mutat. , vol.2 , pp. 425-434
    • Nagase, H.1    Nakamura, Y.2
  • 37
    • 0031813650 scopus 로고    scopus 로고
    • Axin, an inhibitor of the Wnt signalling pathway, interacts with β-catenin, GSK-3β and APC and reduces the β-catenin level
    • Nakamura T., F. Hamada, T. Ishidate, K. Anai, K. Kawahara, K. Toyoshima, and T. Akiyama. 1998. Axin, an inhibitor of the Wnt signalling pathway, interacts with β-catenin, GSK-3β and APC and reduces the β-catenin level. Genes Cells 3: 395-402.
    • (1998) Genes Cells , vol.3 , pp. 395-402
    • Nakamura, T.1    Hamada, F.2    Ishidate, T.3    Anai, K.4    Kawahara, K.5    Toyoshima, K.6    Akiyama, T.7
  • 38
    • 0029982877 scopus 로고    scopus 로고
    • The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration
    • Näthke, I.S., C.L. Adams, P. Polakis, J.H. Sellin, and W.J. Nelson. 1996. The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration. J. Cell Biol. 134: 165-179.
    • (1996) J. Cell Biol. , vol.134 , pp. 165-179
    • Näthke, I.S.1    Adams, C.L.2    Polakis, P.3    Sellin, J.H.4    Nelson, W.J.5
  • 39
    • 0030987826 scopus 로고    scopus 로고
    • Nuclear and cytoplasmic localizations of the adenomatous polyposis coli protein
    • Neufeld, K.L. and R.L. White. 1997. Nuclear and cytoplasmic localizations of the adenomatous polyposis coli protein. Proc. Nact. Acad. Sci. 94: 3034-3039.
    • (1997) Proc. Nact. Acad. Sci. , vol.94 , pp. 3034-3039
    • Neufeld, K.L.1    White, R.L.2
  • 41
    • 0029047954 scopus 로고
    • Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene
    • Oshima, M., H. Oshima, K. Kitagawa, M. Kobayashi, C. Itakura, and M. Taketo. 1995. Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene. Proc. Natl. Acad. Sci. 92: 4482-4486.
    • (1995) Proc. Natl. Acad. Sci. , vol.92 , pp. 4482-4486
    • Oshima, M.1    Oshima, H.2    Kitagawa, K.3    Kobayashi, M.4    Itakura, C.5    Taketo, M.6
  • 42
    • 0030923749 scopus 로고    scopus 로고
    • Dynamics of β-catenin interactions with APC protein regulate epithelial tubulogenesis
    • Pollack, A.L., A.I.M. Barth, Y. Altschuler, W.J. Nelson, and K.E. Mostov. 1997. Dynamics of β-catenin interactions with APC protein regulate epithelial tubulogenesis. J. Cell Biol. 137: 1651-1662.
    • (1997) J. Cell Biol. , vol.137 , pp. 1651-1662
    • Pollack, A.L.1    Barth, A.I.M.2    Altschuler, Y.3    Nelson, W.J.4    Mostov, K.E.5
  • 43
    • 0031557898 scopus 로고    scopus 로고
    • The adenomatous polyposis coli (APC) tumor suppressor
    • Polakis, P. 1997. The adenomatous polyposis coli (APC) tumor suppressor. Biochim. Biophys. Acta 1332: F127-F147.
    • (1997) Biochim. Biophys. Acta , vol.1332
    • Polakis, P.1
  • 45
    • 0031201473 scopus 로고    scopus 로고
    • RP1, a new member of the adenomatous polyposis coli-binding EB1-like gene family, is differentially expressed in activated T cells
    • Renner, C., J.-P. Pfitzenmeier, K. Gerlach, G. Held, S. Ohnesorge, U. Sahin, S. Bauer, and M. Pfreundschuh. 1997. RP1, a new member of the adenomatous polyposis coli-binding EB1-like gene family, is differentially expressed in activated T cells. J. Immunol. 159: 1276-1283.
    • (1997) J. Immunol. , vol.159 , pp. 1276-1283
    • Renner, C.1    Pfitzenmeier, J.-P.2    Gerlach, K.3    Held, G.4    Ohnesorge, S.5    Sahin, U.6    Bauer, S.7    Pfreundschuh, M.8
  • 47
    • 0028953279 scopus 로고
    • The APC protein and E-cadherin form similar but independent complexes with α-catenin, β-catenin, and plako-globin
    • Rubinfeld, B., B. Souza, I. Albert, S. Munemitsu, and P. Polakis. 1995. The APC protein and E-cadherin form similar but independent complexes with α-catenin, β-catenin, and plako-globin. J. Biol. Chem. 270: 5549-5555.
    • (1995) J. Biol. Chem. , vol.270 , pp. 5549-5555
    • Rubinfeld, B.1    Souza, B.2    Albert, I.3    Munemitsu, S.4    Polakis, P.5
  • 48
    • 0029664368 scopus 로고    scopus 로고
    • Binding of GSK3β to the APC-β-Catenin complex and regulation of complex assembly
    • Rubinfeld, B., I. Albert, E. Porfiri, C. Fiol, S. Munemitsu, and P. Polakis. 1996. Binding of GSK3β to the APC-β-Catenin complex and regulation of complex assembly. Science 272: 1023-1026.
    • (1996) Science , vol.272 , pp. 1023-1026
    • Rubinfeld, B.1    Albert, I.2    Porfiri, E.3    Fiol, C.4    Munemitsu, S.5    Polakis, P.6
  • 51
    • 0032484519 scopus 로고    scopus 로고
    • Localization of the adenomatous polyposis coli tumour suppressor protein in the mouse central nervous system
    • Senda, T., S. Lino, K. Matsushita, A. Matsumine, S. Kobayashi, and T. Akiyama. 1998. Localization of the adenomatous polyposis coli tumour suppressor protein in the mouse central nervous system. Neuroscience 83: 857-866.
    • (1998) Neuroscience , vol.83 , pp. 857-866
    • Senda, T.1    Lino, S.2    Matsushita, K.3    Matsumine, A.4    Kobayashi, S.5    Akiyama, T.6
  • 57
    • 0027756014 scopus 로고
    • Association of the APC tumor suppressor protein with catenins
    • Su, L.-K., B. Vogelstein, and K.W. Kinzler. 1993a. Association of the APC tumor suppressor protein with catenins. Science 262: 1734-1737.
    • (1993) Science , vol.262 , pp. 1734-1737
    • Su, L.-K.1    Vogelstein, B.2    Kinzler, K.W.3
  • 60
    • 0003975212 scopus 로고
    • Pathology
    • ed. R.K.S. Phillips, A.D. Spigelman, and J.P.S. Thomson Edward Arnold, London, UK
    • Talbot, I.C. 1994. Pathology. In Familial adenomatous polyposis and other polyposis syndromes (ed. R.K.S. Phillips, A.D. Spigelman, and J.P.S. Thomson), pp. 15-25. Edward Arnold, London, UK.
    • (1994) Familial Adenomatous Polyposis and Other Polyposis Syndromes , pp. 15-25
    • Talbot, I.C.1
  • 62
    • 6844252957 scopus 로고    scopus 로고
    • Germline mutations in the 3′ part of APC exon 15 do not result in truncated proteins and are associated with Attenuated Adenomatous Polyposis Coli
    • van der Luijt, R.B., P. Meera Khan, C. Breukel, C.M.J. Tops, H.F.A. Vasen, R.J. Scott, and R.F. Fodde. 1996. Germline mutations in the 3′ part of APC exon 15 do not result in truncated proteins and are associated with Attenuated Adenomatous Polyposis Coli. Hum. Genet. 98: 727-734.
    • (1996) Hum. Genet. , vol.98 , pp. 727-734
    • Van Der Luijt, R.B.1    Khan, P.M.2    Breukel, C.3    Tops, C.M.J.4    Vasen, H.F.A.5    Scott, R.J.6    Fodde, R.F.7
  • 63
    • 0031888098 scopus 로고    scopus 로고
    • β-catenin: A key mediator of Wnt signaling
    • Willert, K. and R. Nusse. 1998. β-catenin: A key mediator of Wnt signaling. Curr. Opin. Genet. Dev. 8: 95-102.
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 95-102
    • Willert, K.1    Nusse, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.