Identification of an alternative mechanism of degradation of the hypoxia-inducible factor-1α

Journal of Biological Chemistry

Volumn 283, Issue 43, 2008, Pages 29375-29384

  André, Helder ^a   Pereira, Teresa S ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Dept of Cell and Molecular Biology ^*  (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; NUCLEIC ACIDS; OXYGEN; PROTEINS; RNA; TRANSCRIPTION FACTORS;

ALTERNATIVE MECHANISMS; CELLULAR RESPONSES; DEGRADATION PATHWAYS; HIGH AFFINITY BINDINGS; HYDROXYLASES; MASTER REGULATORS; MUTANT PROTEINS; NORMOXIA; OXYGEN CONCENTRATIONS; OXYGEN LEVELS; PROLINE RESIDUES; PROTEASOME; RNA INTERFERENCES; SHORT PERIODS; UBIQUITIN LIGASE; UBIQUITINATION;

DEGRADATION;

CELL EXTRACT; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLINE DERIVATIVE; VON HIPPEL LINDAU PROTEIN;

ARTICLE; CELL CULTURE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; RNA INTERFERENCE; UBIQUITINATION;

ANOXIA; CELL LINE; COBALT; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MODELS, BIOLOGICAL; MUTATION; OXYGEN; PROCOLLAGEN-PROLINE DIOXYGENASE; PROTEASOME ENDOPEPTIDASE COMPLEX; RNA INTERFERENCE; RNA, SMALL INTERFERING; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 57649178183     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M805919200     Document Type: Article

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