Pneumolysin: A double-edged sword during the host-pathogen interaction

Current Molecular Medicine

Volumn 8, Issue 6, 2008, Pages 497-509

  Marriott, Helen M ^a   Mitchell, Timothy J ^b   Dockrell, David H ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Disease pathogenesis; Immune response; Pneumolysin; Pore formation; Streptoccus pneumoniae

Indexed keywords

AUTOLYSIN; BRAIN DERIVED NEUROTROPHIC FACTOR; C REACTIVE PROTEIN; CASPASE 4; CASPASE 6; CATHEPSIN E; CHOLESTEROL; HISTONE H3; IMMUNOGLOBULIN FC FRAGMENT; INTERCELLULAR ADHESION MOLECULE 1; INTERFERON; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 8; LYSOZYME; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MANNOSE BINDING LECTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MONOCYTE CHEMOTACTIC PROTEIN 3; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITRIC OXIDE SYNTHASE; PNEUMOLYSIN; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; RHO KINASE; STREPTOLYSIN O; TOLL LIKE RECEPTOR 4; TRYPTOPHAN; TUMOR NECROSIS FACTOR ALPHA; BACTERIAL PROTEIN; PLY PROTEIN, STREPTOCOCCUS PNEUMONIAE; STREPTOLYSIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; APOPTOSIS; BACTERIAL COLONIZATION; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM CULTURE; CELL DEATH; CELL FUNCTION; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM; DISEASE PREDISPOSITION; DNA MICROARRAY; ENZYME ACTIVATION; EPIGENETICS; EUKARYOTIC CELL; GENE IDENTIFICATION; GENE INSERTION; GENETIC TRANSFORMATION; GENETIC VARIABILITY; HEMOLYSIS; HOST PATHOGEN INTERACTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IMMUNE RESPONSE; LIVER CIRRHOSIS; LUNG INJURY; MACROPHAGE; MEMBRANE FORMATION; MENINGITIS; MUTATIONAL ANALYSIS; NATURAL KILLER CELL; NERVE INJURY; NONHUMAN; OLIGOMERIZATION; PERITONITIS; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; RESPIRATORY SYSTEM; REVIEW; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; STREPTOCOCCUS PNEUMONIAE; TISSUE INJURY; ANIMAL; BIOLOGICAL MODEL; CELL MEMBRANE; CHEMISTRY; COMPLEMENT ACTIVATION; GENETICS; IMMUNE SYSTEM; METABOLISM; MICROBIOLOGY; NERVOUS SYSTEM; PATHOGENICITY;

ANIMALIA; BACTERIA (MICROORGANISMS); EUKARYOTA; STREPTOCOCCUS PNEUMONIAE;

ANIMALS; BACTERIAL PROTEINS; CELL DEATH; CELL MEMBRANE; CHOLESTEROL; COMPLEMENT ACTIVATION; EUKARYOTIC CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNE SYSTEM; MODELS, BIOLOGICAL; NERVOUS SYSTEM; PROTEIN BINDING; RESPIRATORY SYSTEM; STREPTOCOCCUS PNEUMONIAE; STREPTOLYSINS;

EID: 53149104367     PISSN: 15665240     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652408785747924     Document Type: Review

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