Brain-derived neurotrophic factor protects against multiple forms of brain injury in bacterial meningitis

Journal of Infectious Diseases

Volumn 191, Issue 1, 2005, Pages 40-45

  Bifrare, Yoeng Delphine ^a   Kummer, Jürg ^a   Joss, Philipp ^a   Täuber, Martin G ^a   Leib, Stephen L ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; APOPTOSIS INDUCING FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; CASPASE 3; ENZYME; GLUTAMIC ACID; SODIUM CHLORIDE;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BACTERIAL MENINGITIS; BRAIN CELL; BRAIN CORTEX; BRAIN DISEASE; CELL DEATH; HIPPOCAMPUS; HISTOPATHOLOGY; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOCOCCUS AGALACTIAE; STREPTOCOCCUS PNEUMONIAE; TREATMENT OUTCOME;

ANIMALS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DEATH; CELL NUCLEUS; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; FLAVOPROTEINS; HIPPOCAMPUS; MEMBRANE PROTEINS; MENINGITIS, BACTERIAL; MENINGITIS, PNEUMOCOCCAL; NECROSIS; RATS; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS AGALACTIAE; STREPTOCOCCUS PNEUMONIAE;

EID: 11144321597     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/426399     Document Type: Article

References (37)

1. Schuchat A, Robinson K, Wenger JD, et al. Bacterial meningitis in the United States in 1995. Active Surveillance Team. N Engl J Med 1997; 337:970-6.
2. Harvey D, Holt DE, Bedford H. Bacterial meningitis in the newborn: a prospective study of mortality and morbidity. Semin Perinatol 1999; 23:218-25.
3. Bedford H, de Louvois J, Halket S, Peckham C, Hurley R, Harvey D. Meningitis in infancy in England and Wales: follow up at age 5 years. BMJ 2001; 323:533-6.
4. Grimwood K, Anderson VA, Bond L, et al. Adverse outcomes of bacterial meningitis in school-age survivors. Pediatrics 1995; 95:646-56.
5. Grimwood K, Anderson P, Anderson V, Tan L, Nolan T. Twelve year outcomes following bacterial meningitis: further evidence for persisting effects. Arch Dis Child 2000; 83:111-6.
6. van de Beek D, Schmand B, de Gans J, et al. Cognitive impairment in adults with good recovery after bacterial meningitis. J Infect Dis 2002; 186:1047-52.
7. Merkelbach S, Sittinger H, Schweizer I, Muller M. Cognitive outcome after bacterial meningitis. Acta Neurol Scand 2000; 102:118-23.
8. Free SL, Li LM, Fish DR, Shorvon SD, Stevens JM. Bilateral hippocampal volume loss in patients with a history of encephalitis or meningitis. Epilepsia 1996; 37:400-5.
9. Nau R, Soto A, Bruck W. Apoptosis of neurons in the dentate gyms in humans suffering from bacterial meningitis. J Neuropathol Exp Neurol 1999; 58:265-74.
10. Leib SL, Kim YS, Chow LL, Sheldon RA, Täuber MG. Reactive oxygen intermediates contribute to necrotic and apoptotic neuronal injury in an infant rat model of bacterial meningitis due to group B streptococci. J Clin Invest 1996; 98:2632-9.
11. Zysk G, Bruck W, Gerber J, Bruck Y, Prange HW, Nau R. Anti-inflammatory treatment influences neuronal apoptotic cell death in the dentate gyrus in experimental pneumococcal meningitis. J Neuropathol Exp Neurol 1996; 55:722-8.
12. Horch HW, Kruttgen A, Portbury SD, Katz LC. Destabilization of cortical dendrites and spines by BDNF. Neuron 1999; 23:353-64.
13. Huang EJ, Reichardt LF. Neurotrophins: roles in neuronal development and function. Annu Rev Neurosci 2001; 24:677-736.
14. Bibel M, Barde YA. Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system. Genes Dev 2000; 14:2919-37.
15. Gianinazzi C, Grandgirard D, Imboden H, et al. Caspase-3 mediates hippocampal apoptosis in pneumococcal meningitis. Acta Neuropathol (Berl) 2003; 105:499-507.
16. Bifrare YD, Gianinazzi C, Imboden H, Leib SL, Täuber MG. Bacterial meningitis causes two distinct forms of cellular damage in the hippocampal dentate gyrus in infant rats. Hippocampus 2003; 13:481-8.
17. Han BH, D'Costa A, Back SA, et al. BDNF blocks caspase-3 activation in neonatal hypoxia-ischemia. Neurobiol Dis 2000; 7:38-53.
18. Han BH, Holtzman DM. BDNF protects the neonatal brain from hypoxic-ischemic injury in vivo via the ERK pathway. J Neurosci 2000; 20:5775-81.
19. Hisatomi T, Sakamoto T, Murata T, et al. Relocalization of apoptosis-inducing factor in photoreceptor apoptosis induced by retinal detachment in vivo. Am J Pathol 2001; 158:1271-8.
20. Leib SL, Heimgartner C, Bifrare YD, Loeffler JM, Täuber MG. Dexamethasone aggravates hippocampal apoptosis and learning deficiency in pneumococcal meningitis in infant rats. Pediatr Res 2003; 54:353-7.
21. Leib SL, Kim YS, Chow LL, Sheldon RA, Täuber MG. Reactive oxygen intermediates contribute to necrotic and apoptotic neuronal injury in an infant rat model of bacterial meningitis due to group B streptococci. J Clin Invest 1996; 98:2632-9.
22. Leib SL, Kim YS, Ferriero DM, Täuber MG. Neuroprotective effect of excitatory amino acid antagonist kynurenic acid in experimental bacterial meningitis. J Infect Dis 1996; 173:166-71.
23. Leib SL, Kim YS, Black SM, Tureen JH, Täuber MG. Inducible nitric oxide synthase and the effect of aminoguanidine in experimental neonatal meningitis. J Infect Dis 1998; 177:692-700.
24. Leib SL, Clements JM, Lindberg RL, et al. Inhibition of matrix metalloproteinases and tumour necrosis factor α converting enzyme as adjuvant therapy in pneumococcal meningitis. Brain 2001; 124:1734-42.
25. Pfister L-A, Tureen JH, Shaw S, et al. Endothelin inhibition improves cerebral blood flow and is neuroprotective in pneumococcal meningitis. Ann Neurol 2000; 47:329-35.
26. Pelleymounter MA, Cullen MJ, Wellman CL. Characteristics of BDNF-induced weight loss. Exp Neurol 1995; 131:229-38.
27. Braun JS, Novak R, Murray PJ, et al. Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus. J Infect Dis 2001; 184:1300-9.
28. Yan Q, Rosenfeld RD, Matheson CR, et al. Expression of brain-derived neurotrophic factor protein in the adult rat central nervous system. Neuroscience 1997; 78:431-48.
29. Zou J, Bretlau P, Pyykko I, et al. Comparison of the protective efficacy of neurotrophins and antioxidants for vibration-induced trauma. ORL J Otorhinolaryngol Relat Spec 2003; 65:155-61.
30. Galvin KA, Oorschot DE. Continuous low-dose treatment with brain-derived neurotrophic factor or neurotrophin-3 protects striatal medium spiny neurons from mild neonatal hypoxia/ischemia: a stereological study. Neuroscience 2003; 118:1023-32.
31. Leib SL, Kim YS, Black SM, Tureen JH, Täuber MG. Inducible nitric oxide synthase and the effect of aminoguanidine in experimental neonatal meningitis. J Infect Dis 1998; 177:692-700.
32. Leib SL, Kim YS, Ferriero DM, Täuber MG. Neuroprotective effect of excitatory amino acid antagonist kynurenic acid in experimental bacterial meningitis. J Infect Dis 1996; 173:166-71.
33. Ventimiglia R, Mather PE, Jones BE, Lindsay RM. The neurotrophins BDNF, NT-3 and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro. Eur J Neurosci 1995; 7:213-22.
34. Guerra-Romero L, Tureen JH, Fournier MA, Makrides V, Täuber MG. Amino acids in cerebrospinal and brain interstitial fluid in experimental pneumococcal meningitis. Pediatr Res 1993; 33:510-3.
35. Auer M, Pfister LA, Leppert D, Täuber MG, Leib SL. Effects of clinically used antioxidants in experimental pneumococcal meningitis. J Infect Dis 2000; 182:347-50.
36. Cao G, Clark RS, Pei W, et al. Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation. J Cereb Blood Flow Metab 2003; 23:1137-50.
37. Li L, Shui QX, Zhao ZY. Regulation of brain-derived neurotrophic factor (BDNF) expression following antibiotic treatment of experimental bacterial meningitis. J Child Neurol 2003; 18:828-34.