The role of interferon-γ in murine pneumococcal pneumonia

Journal of Infectious Diseases

Volumn 185, Issue 1, 2002, Pages 91-97

  Rijneveld, Anita W ^a   Lauw, Fanny N ^a   Schultz, Marc J ^a   Florquin, Sandrine ^a   Te Velde, Anje A ^a   Speelman, Peter ^a   van Deventer, Sander J H ^a   Van Der Poll, Tom ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTEREMIA; CONTROLLED STUDY; HISTOPATHOLOGY; HOST RESISTANCE; INOCULATION; LOBAR PNEUMONIA; MALE; MORTALITY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIAE;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; GRANULOCYTES; IMMUNITY, NATURAL; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-6; LUNG; MACROPHAGE-1 ANTIGEN; MALE; MICE; MICE, MUTANT STRAINS; NITRIC OXIDE; PNEUMONIA, PNEUMOCOCCAL; RECEPTORS, INTERFERON; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036138508     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/338122     Document Type: Article

References (51)

1. Severe community-acquired pneumonia: Epidemiology and prognostic factors
2. Guidelines for the initial management of adults with community-acquired pneumonia: Diagnosis, assessment of severity, and initial antimicrobial therapy
3. Epidemiology of emerging pneumococcal drug resistance: Implications for treatment and prevention
4. Role of cytokines in pulmonary antimicrobial host defense
5. Cellular responses to interferon-gamma
6. Interferon-gamma, the activated macrophage, and host defense against microbial challenge
7. In vivo and in vitro activation of alveolar macrophages by recombinant interferon-gamma
8. Activation of mouse peritoneal macrophages in vitro and in vivo by interferon-gamma
9. Activation of human macrophages: Comparison of other cytokines with interferon-gamma
10. In vitro activation of the antibacterial activity of human pulmonary macrophages by recombinant gamma interferon
11. In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection
12. Impaired macrophage listericidal and cytokine activities are responsible for the rapid death of Listeria monocytogenes-infected IFN-gamma receptor-deficient mice
13. Disseminated tuberculosis in interferon gamma gene-disrupted mice
14. An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection
15. Effector mechanisms responsible for gamma interferon-mediated host resistance to Legionella pneumophila lung infection: The role of endogenous nitric oxide differs in susceptible and resistant murine hosts
16. Effect of murine interferon gamma on murine toxoplasmosis
17. Protection of mice against the intracellular bacterium Listeria monocytogenes by recombinant immune interferon
18. Recombinant interferon-gamma and chemotherapy with isoniazid and rifampicin in experimental murine tuberculosis
19. Intratracheal interferon-gamma augments pulmonary defenses in experimental legionellosis
20. Interferon-gamma (IFN-gamma) treatment decreases the inflammatory response in chronic Pseudomonas aeruginosa pneumonia in rats
21. Role of gamma interferon in the pathogenesis of bacteremic pneumococcal pneumonia
22. Immune response in mice that lack the interferon-gamma receptor
23. Purification and further characterization of an anti-murine interferon-gamma monoclonal neutralizing antibody
24. Systemic release and protective role of IL-10 in staphylococcal enterotoxin B-induced shock in mice
25. The role of IFN-gamma in the pathology of experimental endotoxemia
26. Interleukin-10 impairs host defense in murine pneumococcal pneumonia
27. Interleukin-6 gene-deficient mice show impaired defense against pneumococcal pneumonia
28. Passive immunization against tumor necrosis factor-alpha impairs host defense during pneumococcal pneumonia in mice
29. Neutrophil Mac-1 and MEL-14 adhesion proteins inversely regulated by chemotactic factors
30. Functional role of type I and type II interferons in antiviral defense
31. Response to influenza infection in mice with a targeted disruption in the interferon gamma gene
32. Tumor necrosis factor mediates lung antibacterial host defense in murine Klebsiella pneumonia
33. Neutralization of macrophage inflammatory protein-2 attenuates neutrophil recruitment and bacterial clearance in murine Klebsiella pneumonia
34. IL-12 gene therapy protects mice in lethal Klebsiella pneumonia
35. Neutralization of IL-10 increases survival in a murine model of Klebsiella pneumonia
36. Effects of gamma-interferon on human neutrophils: Protection from deterioration on storage
37. Recombinant interferon gamma for treatment of chronic granulomatous disease and other disorders
38. Impact of interferon-gamma receptor deficiency on experimental Staphylococcus aureus septicemia and arthritis
39. Role of interferon-gamma in experimental gram-negative sepsis
40. IFN-gamma involvement in the severity of gram-negative infections in mice
41. Evidence for IFN-gamma as a mediator of the lethality of endotoxin and tumor necrosis factor-alpha
42. Leukocyte activation in the peripheral blood of patients with cirrhosis of the liver and SIRS: Correlation with serum interleukin-6 levels and organ dysfunction
43. The systemic administration of gamma interferon inhibits collagen synthesis and acute inflammation in a murine skin wounding model
44. Functional characterization of the rat chemokine KC and its importance in neutrophil recruitment in a rat model of pulmonary inflammation
45. Genetic approaches to study chemokine function
46. A pivotal role for interferon-gamma in protection against group A streptococcal skin infection
47. IFN-gamma-independent production of IL-12 during murine endotoxemia
48. IL-4 neutralization or TNF-alpha treatment ameliorate disease by an intracellular pathogen in IFN-gamma receptor-deficient mice
49. Multiple defects of immune cell function in mice with disrupted interferon-gamma genes
50. Interferon gamma receptor deficient mice are resistant to endotoxic shock
51. Interferon-gamma is essential for the development of cerebral malaria