The apoptotic response to pneumolysin is toll-like receptor 4 dependent and protects against pneumococcal disease

Infection and Immunity

Volumn 73, Issue 10, 2005, Pages 6479-6487

  Srivastava, Amit ^a   Henneke, Philipp ^b   Visintin, Alberto ^c   Morse, Sarah C ^a   Martin, Victoria ^a   Watkins, Claire ^a   Paton, James C ^d   Wessels, Michael R ^a   Golenbock, Douglas T ^c   Malley, Richard ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CASPASE INHIBITOR; CYTOLYSIN; PNEUMOLYSIN; RECEPTOR BLOCKING AGENT; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 4 ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CELL ASSAY; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVITY; EPITHELIUM CELL; EXPERIMENTAL MODEL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INFECTION RESISTANCE; INFLAMMATION; LIGAND BINDING; MALE; MORTALITY; MOUSE; MOUSE STRAIN; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE; WILD TYPE;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; APOPTOSIS; BACTERIAL PROTEINS; CASPASES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED STRAINS; NASOPHARYNX; PNEUMOCOCCAL INFECTIONS; STREPTOCOCCUS PNEUMONIAE; STREPTOLYSINS;

EID: 25444523483     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.73.10.6479-6487.2005     Document Type: Article

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